Hub : Genes

BICD2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0610 0.0230 3.0e-05 0.040 0.042 0.021 0.040 0.032 1.2e-05 6.9e-06 1.2e-03 1.2e-05 7.8e-05
2 GTEx Artery Tibial 0.0646 0.0406 9.9e-03 0.007 NA 0.001 NA -0.001 8.1e-02 NA 2.7e-01 NA 4.0e-01
3 GTEx Brain Cerebellar Hemisphere 0.2700 0.1090 3.6e-03 0.055 NA -0.001 NA 0.038 1.6e-02 NA 3.4e-01 NA 3.9e-02
4 GTEx Brain Cerebellum 0.2280 0.1200 8.3e-03 0.065 NA 0.172 NA 0.134 5.6e-03 NA 8.5e-06 NA 9.1e-05
5 GTEx Brain Nucleus accumbens basal ganglia 0.1340 0.0650 8.7e-03 0.195 NA 0.008 NA 0.163 6.2e-06 NA 2.0e-01 NA 3.8e-05
6 GTEx Colon Sigmoid 0.2070 0.0810 2.6e-03 0.001 NA 0.033 NA 0.057 2.8e-01 NA 2.5e-02 NA 4.6e-03
7 GTEx Esophagus Muscularis 0.0950 0.0430 3.8e-03 0.015 NA 0.069 NA 0.060 3.9e-02 NA 5.0e-05 NA 1.6e-04
8 GTEx Skin Sun Exposed Lower leg 0.1030 0.0450 7.1e-03 0.053 NA 0.028 NA 0.040 3.1e-05 NA 2.0e-03 NA 2.7e-04
9 GTEx Spleen 0.2590 0.0910 2.9e-04 0.252 NA 0.064 NA 0.243 3.8e-07 NA 1.0e-02 NA 6.4e-07
10 GTEx Whole Blood 0.0640 0.0290 2.2e-03 0.022 NA 0.013 NA 0.014 3.4e-03 NA 2.1e-02 NA 1.8e-02
11 METSIM Adipose 0.1015 0.0350 1.5e-06 0.013 0.034 0.028 0.039 0.024 4.1e-03 6.4e-06 4.6e-05 1.3e-06 1.2e-04
12 TCGA Head and Neck Squamous Cell Carcinoma 0.1375 0.0550 1.1e-08 0.059 0.067 0.060 NA 0.060 2.9e-07 5.2e-08 2.4e-07 NA 2.4e-07
13 TCGA Kidney Renal Papillary Cell Carcinoma 0.1010 0.0770 5.8e-03 0.030 0.026 0.020 NA 0.025 7.1e-03 1.3e-02 2.5e-02 NA 1.4e-02
14 TCGA Brain Lower Grade Glioma 0.0642 0.0370 1.9e-06 0.023 0.049 0.042 NA 0.044 1.0e-03 2.9e-06 1.3e-05 NA 8.3e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 1.1 1.8 4.8 -1.6 -1.3 -2.1 -0.6 -1.1 0.0 -0.7 0.0 -1.3 -1.3 -1.3 -0.8 -2.0 -2.2
Bipolar Disorder or Schizophrenia 0.3 0.8 2.3 -0.6 -1.1 -1.3 1.5 -1.1 -0.4 -0.2 0.4 -0.4 -0.5 -0.7 -0.1 -1.4 -0.9
Depressed Affect (Nagel 2018) 0.1 0.2 0.5 -0.3 0.6 0.1 0.3 -0.1 -0.7 -0.4 -0.5 -0.2 -0.3 0.2 -0.2 -0.6 0.5
Depression (Nagel 2018) 0.1 0.2 1.3 0.3 0.6 0.3 1.1 0.3 0.0 0.5 -0.1 0.3 0.3 -0.3 0.1 0.2 0.4
Intelligence (Savage-Jansen 2018) 0.2 0.6 2.2 -0.9 -0.5 0.1 -1.5 -0.8 -0.5 -0.8 1.2 -0.2 -0.3 -0.8 0.3 -0.1 -1.0
Neuroticism (Nagel 2018) 0.1 0.2 1.3 -0.5 -0.2 0.2 0.1 0.2 -1.1 0.3 0.2 -0.1 -0.1 0.4 0.5 -0.7 0.1
Schizophrenia (2018) 0.3 0.6 5.8 0.5 -0.4 0.0 2.4 -0.6 -0.2 0.2 0.5 0.5 0.5 0.1 0.5 -0.1 0.7
Schizophrenia vs Biploar Disorder 1.5 2.0 5.1 1.5 -1.3 2.0 2.1 -0.3 1.0 -0.2 -0.5 1.8 1.8 0.1 0.4 2.3 1.6
Worry (Nagel 2018) 0.2 0.5 1.4 0.0 -0.8 0.8 0.1 1.0 -0.4 1.2 0.4 0.5 0.4 1.0 1.1 -0.3 -0.1
Alzheimer’s Disease (in mother) 0.3 0.4 1.2 0.0 0.5 -0.2 -0.9 -0.6 -0.6 -1.1 -0.9 -0.1 -0.1 -0.7 -1.1 0.4 0.4
Alzheimer’s Disease (in father) 1.5 1.6 3.8 -1.0 -0.9 -1.1 0.9 -0.1 0.1 -1.1 -1.1 -1.5 -1.5 -1.8 -1.9 -1.4 -1.6
Alzheimer’s Disease (including proxy) 0.5 0.7 2.6 0.2 -0.8 -0.2 0.6 0.2 -0.2 -1.5 -1.5 -0.2 -0.2 -1.2 -1.6 0.2 -0.0
Crohns Disease (2017) 1.8 3.9 14.7 3.8 -2.3 1.5 1.6 0.0 2.5 0.5 -0.8 2.0 2.0 0.9 1.1 2.2 2.6
Irritable Bowel Disease (IBD) 2.3 5.4 17.1 4.1 -2.1 2.5 1.6 0.9 2.9 0.5 -0.4 2.6 2.6 1.4 2.0 2.5 3.2
Ulcerative Colitis (UC) 2.5 4.7 9.9 3.1 -0.9 2.8 1.4 1.8 2.3 1.1 0.2 2.5 2.5 1.5 2.4 2.2 3.1
Major Depression (MDD) 0.9 1.1 2.3 -1.4 -0.6 -1.5 1.2 0.3 -1.1 -0.2 0.3 -1.0 -1.1 -1.5 -0.6 -1.4 -1.3
Reaction Time 1.0 2.0 3.4 1.6 -0.7 1.8 1.8 1.1 1.7 1.8 -1.3 1.3 1.3 -0.6 0.3 1.7 1.5
Verbal and Numeric Reasoning (VNR) 0.3 0.7 2.7 -1.3 -1.6 -0.0 -0.8 -0.3 -1.1 0.0 1.2 0.3 0.3 -0.2 0.5 0.7 -1.1
Breast Cancer 0.7 1.6 6.1 -1.1 0.1 -1.4 -1.8 -2.5 0.1 -1.6 -0.2 -1.2 -1.2 -1.3 -0.6 -1.0 -1.1
Ovarian Cancer 1.2 1.6 10.0 0.6 1.9 -0.8 -3.2 -1.1 1.0 -0.9 0.9 -0.8 -0.7 0.6 0.1 -1.0 -0.9
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.5 0.7 2.7 -0.6 1.0 -0.2 -1.6 -0.2 -0.3 -0.7 1.6 -0.0 0.0 1.3 0.7 -0.5 -0.4
Bipolar Disorder (2011) 1.0 1.0 2.9 -1.2 -0.1 -0.9 0.9 -0.2 0.2 -0.6 -1.2 -0.6 -1.1 -1.1 -1.2 -1.1 -1.7
Body Mass Index (BMI) (2010) 0.9 1.3 2.7 -1.1 1.3 -1.6 -0.9 0.5 -1.6 -1.5 0.1 -1.3 -1.2 0.8 -0.9 -0.9 -0.9
Coronary Artery Disease (CAD) 0.2 0.3 2.4 0.2 -1.5 0.6 0.3 -0.3 0.3 0.4 -0.2 0.4 0.4 0.3 0.1 0.7 0.2
Crohns Disease (2012) 1.4 2.3 5.9 2.3 -2.4 1.2 1.9 -0.6 1.8 -0.2 0.3 1.7 1.7 0.7 1.1 1.4 1.4
Mean Putamen Volume 0.3 0.4 1.4 0.5 -1.2 0.5 0.9 0.5 0.8 -0.4 0.3 0.5 0.5 0.3 0.4 0.4 -0.7
Fasting Glucose 0.3 0.4 1.7 0.7 -0.8 0.4 1.0 1.0 0.2 1.3 -0.3 0.5 0.5 0.3 0.2 -0.1 -0.2
HbA1C 0.3 0.4 2.5 -0.7 0.2 0.1 0.3 0.3 -1.6 0.9 0.5 -0.1 -0.0 0.9 0.2 0.2 0.1
HDL Cholesterol 0.5 0.9 3.0 -1.2 -1.6 -0.7 0.8 0.6 0.1 -1.0 0.1 -0.7 -0.7 -1.0 -0.8 -0.8 -1.7
LDL Cholesterol 0.6 1.0 4.1 0.7 -0.4 0.4 2.0 -0.7 1.0 0.8 -1.6 0.7 0.8 -0.9 -0.8 1.2 0.6
Lupus 0.3 0.4 1.5 -0.9 -0.1 -0.3 -0.2 1.2 -1.2 0.1 0.1 -0.6 -0.6 0.0 -0.2 -0.8 -0.2
Neuroticism (2016) 0.3 0.4 2.6 -0.1 1.6 -0.1 -0.1 0.9 -0.3 0.9 -0.1 -0.0 -0.5 0.0 0.1 0.3 1.1
Primary Biliary Cirrhosis 0.7 1.0 3.2 1.4 0.0 1.1 -0.2 0.2 0.4 -0.5 0.8 1.2 1.2 0.5 1.3 1.2 1.8
Rheumatoid Arthritis 0.2 0.3 1.8 0.1 -0.1 0.7 1.3 0.6 0.2 0.3 0.4 0.3 0.4 0.4 0.0 0.5 -0.1
Schizophrenia (2014) 0.2 0.4 3.9 0.3 -0.9 0.4 2.0 -0.3 0.1 0.1 0.0 0.5 0.5 -0.3 0.3 0.0 0.3
Triglycerides 0.5 0.8 4.3 1.5 -0.2 0.4 0.0 0.5 -0.9 -0.6 -2.1 0.5 0.4 -0.5 -1.1 0.5 1.1
Type 2 Diabetes (T2D) (2012) 1.6 1.9 8.5 1.0 2.1 -0.6 -1.3 1.0 -0.7 0.6 -2.9 -0.7 -0.7 -1.4 -1.8 0.3 1.5
Ulcerative Colitis 1.5 2.2 4.7 2.1 -0.7 2.0 1.6 1.8 0.8 1.4 -0.9 1.5 1.5 0.0 0.7 1.5 2.2
Blood Eosinophil Count 0.4 2.7 9.1 2.1 2.0 1.1 -0.4 3.0 0.2 2.6 -0.8 0.8 0.8 -0.3 1.2 0.9 2.8
Blood Platelet Count 3.8 44.0 96.8 5.9 -0.1 6.9 8.7 2.6 5.6 8.4 -2.0 7.9 7.9 2.0 5.9 9.2 9.8
Blood Red Count 0.3 2.7 16.7 1.4 0.2 0.7 2.1 2.9 0.8 4.1 -0.7 0.6 0.6 0.2 1.1 0.6 1.4
Blood White Count 1.6 11.5 46.6 4.0 2.0 2.8 0.7 1.7 1.3 4.2 -3.2 3.4 3.5 0.8 2.3 4.8 6.8
Heel T-Score 2.8 22.0 55.2 7.2 -1.9 5.2 7.4 6.8 3.4 4.6 -1.1 4.5 4.6 1.6 3.1 3.9 4.5
BMI 0.7 4.2 9.2 -1.3 2.7 -2.9 -1.9 -1.2 -2.1 -2.1 1.4 -2.7 -2.6 0.6 -0.6 -3.0 -1.5
Height 1.8 33.8 139.2 -5.2 -8.4 -3.8 -2.4 -2.7 0.3 -8.5 4.1 -3.9 -4.1 -1.7 -3.7 -8.4 -11.8
Waist Hip Ratio (WHR) 5.3 23.7 49.3 7.0 -2.8 5.8 4.8 3.8 4.7 4.9 -1.5 6.1 6.1 1.6 3.9 5.1 6.1
Systolic Blood Pressure 0.3 1.4 6.2 0.5 -0.4 -0.9 -0.5 0.4 -0.3 -1.2 -2.2 -0.6 -0.7 -2.5 -1.6 -1.4 -1.0
Smoking Status 0.4 1.0 2.7 1.4 0.5 1.4 0.3 1.0 0.7 -0.5 0.6 0.9 0.8 0.3 1.7 1.1 1.5
Allergy or Eczema 0.6 1.6 8.5 0.7 0.8 -0.3 0.3 0.7 0.0 0.8 -2.9 -0.5 -0.4 -2.2 -2.0 0.3 1.4
Cardiovascular Disease 0.3 0.9 3.2 1.8 -0.9 0.4 -0.2 1.0 0.4 -1.5 1.6 0.5 0.6 0.4 1.0 -0.5 -0.1
Hypothyroidism (self reported) 0.6 1.4 3.6 0.3 -0.8 0.9 1.5 1.1 -0.9 0.7 -1.9 1.1 1.1 -0.4 -0.4 1.8 1.9
Respiratory disease 0.6 1.3 4.3 2.1 0.8 0.5 -0.6 1.6 1.2 0.5 -0.4 0.9 1.0 0.7 0.6 1.3 1.8
Type 2 Diabetes (T2D) (2018) 0.9 1.6 4.9 2.2 1.2 1.5 0.7 2.2 0.8 0.7 -0.5 0.9 0.9 0.8 0.5 0.8 2.2
Lung FEV1/FVC ratio 0.3 1.3 5.9 -0.7 2.4 -1.1 0.6 -1.2 -0.3 0.5 -1.3 -1.1 -1.0 -1.6 -0.8 -0.7 0.8
Lung FVC 1.3 6.6 17.6 -4.2 3.3 -2.9 -2.7 -1.0 -2.6 0.1 -0.6 -3.5 -3.6 -0.8 -2.4 -1.9 -2.0
Neuroticism 0.4 1.0 4.1 0.7 -1.0 1.2 0.7 2.0 -0.6 0.5 0.9 0.9 0.8 1.1 1.3 0.2 0.7
Chronotype (morning person) 0.3 0.7 4.0 0.8 -1.0 0.6 2.0 0.5 1.1 0.6 -1.0 0.0 0.1 -0.7 -0.5 0.1 -0.0
Hair Pigment 0.0 0.3 1.8 -0.2 0.4 0.2 -0.0 -0.2 1.3 -0.3 1.1 0.3 0.3 0.9 0.6 0.3 0.1
Tanning 0.3 3.1 7.5 -2.7 -0.8 -1.3 -0.4 -1.2 -2.7 -1.2 1.1 -2.2 -2.3 -0.8 -0.9 -2.0 -2.5
Hand grip strength (left) 0.5 1.4 4.8 -0.3 -1.2 -1.5 -1.4 -0.7 -0.8 -1.4 0.5 -0.9 -0.9 -0.2 -0.5 -1.8 -2.2
Number of treatments/medications taken 0.5 1.0 2.8 1.7 -0.4 1.1 1.0 1.3 -0.2 -0.4 1.2 0.7 0.7 1.1 1.3 -0.6 0.7
Average weekly spirits intake 0.2 0.3 1.0 -0.3 0.5 -0.1 -0.3 0.5 -1.0 -1.0 0.5 -0.4 -0.4 0.5 -0.3 -0.5 -0.4
Sensitivity / hurt feelings 0.3 0.5 2.5 -0.2 -1.6 -0.2 -0.2 0.9 -1.1 -0.1 0.0 -0.5 -0.5 -0.8 -0.5 -0.4 -0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 2.0 0.5 1.0 0.4 1.4 1.4 0.3 0.9 -0.8 0.0 0.1 -0.8 -0.0 -0.1 0.4
Hearing difficulty/problems: Yes 0.9 1.3 4.8 1.6 -0.9 1.0 1.0 -0.3 2.2 0.0 0.7 1.1 1.2 1.7 1.2 0.1 0.6
Relative age of first facial hair 0.3 0.6 1.5 -1.1 -1.1 -0.4 1.0 -0.2 -1.1 1.2 0.3 -0.4 -0.4 -0.7 -0.2 -0.5 -0.6
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.7 -0.2 -1.6 0.2 1.5 0.4 -0.3 -0.3 -1.0 -0.1 -0.0 0.6 -0.8 -0.3 -0.3
Ever used hormone-replacement therapy (HRT) 0.5 0.6 3.7 -0.2 0.1 -0.1 0.5 -1.6 1.9 -1.3 0.1 0.4 0.3 -0.2 0.2 0.1 -0.2
Ever had hysterectomy (womb removed) 0.6 0.6 1.9 0.5 -0.6 0.7 0.1 -0.5 1.0 0.3 -0.6 1.2 1.2 -0.6 0.2 1.4 1.0
Systolic blood pressure, automated reading 0.5 1.4 3.8 -0.2 1.5 -1.6 -1.0 -0.9 -0.5 -1.9 -1.2 -0.9 -0.9 -1.2 -1.5 -1.3 -0.5
Eye problems/disorders: Diabetes related eye disease 3.2 3.6 6.5 2.4 0.2 1.9 2.1 1.1 1.7 1.8 0.8 2.5 2.5 2.2 1.9 1.6 2.1
Angina 0.5 0.7 2.2 -0.6 0.1 -0.5 0.4 -0.1 -1.5 -0.3 0.8 -0.9 -1.0 -0.1 0.1 -1.5 -1.4
Medication for hormone replacement therapy 0.3 0.4 3.1 -0.6 0.0 0.3 0.3 -0.1 1.8 -0.2 0.4 0.6 0.6 0.5 0.4 0.6 -0.2
Vitamin and mineral supplements 1.6 2.2 6.9 -1.8 0.3 -1.5 -0.7 -1.9 -1.3 -0.8 -2.6 -1.2 -1.2 -1.6 -2.6 0.2 -0.7
Supplements: Zinc 0.3 0.4 4.2 -0.0 0.3 -0.5 2.0 0.0 -0.4 0.0 0.6 -0.2 -0.1 -0.5 0.1 -0.2 -0.0
Medication: Co-codamol 2.6 3.0 9.7 2.3 1.1 1.9 -0.2 2.3 1.1 0.5 0.8 1.6 1.6 1.9 1.7 1.9 3.1
Medication: Metformin 1.5 2.1 5.8 1.9 1.8 1.8 0.7 1.6 1.7 0.6 -0.0 1.4 1.4 0.9 1.2 1.1 2.4
Diabetes (father) 1.5 1.8 5.5 0.0 -0.6 0.9 1.6 2.0 0.2 2.1 -2.3 0.6 0.6 -1.5 -0.6 1.6 1.4
Diabetes (mother) 0.6 0.8 2.4 0.3 -0.6 0.9 1.1 1.5 1.6 0.6 0.8 0.9 0.9 0.8 0.7 0.5 0.2
Severe depression (siblings) 0.4 0.4 1.4 -0.3 0.9 -0.1 -1.2 0.1 -1.0 0.8 -1.2 -0.1 -0.1 -0.2 -0.4 0.3 0.3
Pack years adult smoking proportion 0.7 1.0 3.5 0.6 1.2 0.5 1.7 0.9 -0.4 0.5 -1.9 -0.5 -0.6 -1.3 -0.9 -0.4 1.1
Impedance of leg (right) 2.9 14.2 30.6 3.8 -2.9 3.8 5.5 2.9 3.7 5.5 -3.4 4.1 4.0 -0.9 1.5 4.3 3.6
Leg fat-free mass (left) 3.0 16.0 32.1 -4.2 0.6 -4.4 -4.9 -2.7 -2.6 -5.7 2.3 -4.6 -4.6 -0.1 -2.9 -5.5 -5.5
Trunk fat percentage 0.1 0.6 2.3 1.3 0.0 -0.7 0.1 0.1 0.5 -1.3 0.7 -0.4 -0.4 0.2 0.2 -1.5 -0.9
Hand grip strength (right) 0.9 2.4 7.3 -0.9 -0.9 -2.0 -2.3 -0.9 -0.7 -1.4 0.2 -1.7 -1.7 -0.4 -1.0 -2.2 -2.7
Townsend deprivation index at recruitment 0.2 0.3 0.8 0.2 0.5 0.9 -0.5 0.9 0.1 0.4 0.0 0.1 0.0 0.9 0.5 0.3 0.6
Current tobacco smoking 0.6 1.0 3.9 1.3 2.0 0.9 -0.1 -0.4 1.0 0.2 -0.7 0.4 0.4 -0.0 0.5 1.5 1.8
Average weekly fortified wine intake 1.3 1.5 4.3 -1.3 0.4 -1.3 -1.3 -2.1 -1.8 -1.7 0.8 -1.1 -1.1 -0.1 -0.3 -1.5 -1.0
Maternal smoking around birth 0.5 0.8 4.3 1.4 -0.5 0.6 0.5 1.0 0.3 0.1 -2.1 0.2 0.2 -1.0 -1.1 0.2 0.5
Fed-up feelings 0.3 0.6 2.3 -0.6 1.5 -0.4 -0.6 0.3 -1.2 0.7 -0.1 -1.0 -1.0 -0.1 -0.2 -1.1 -0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 2.1 0.2 1.4 -0.6 0.1 0.1 -0.1 -0.5 -0.2 -0.4 -0.4 -0.5 -0.0 -0.1 0.2
Relative age voice broke 0.4 0.6 2.4 -0.6 -1.5 -0.2 1.5 -0.2 -0.5 1.2 0.5 0.5 0.5 0.1 0.6 0.2 -0.0
Taking other prescription medications 0.7 1.1 2.9 1.6 -1.7 1.3 1.2 1.1 0.1 -0.8 0.3 1.0 1.0 1.1 0.7 0.4 1.1
Age when periods started (menarche) 0.3 0.6 2.1 0.3 0.9 0.5 -0.5 1.2 0.4 1.2 -0.8 0.4 0.4 -0.4 0.2 1.2 1.4
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.3 -0.0 0.1 0.4 1.1 0.7 -0.4 -0.7 -0.9 -0.7 -0.7 -0.8 -1.0 -0.2 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 5.0 1.6 0.0 1.1 2.2 2.2 0.5 1.4 -0.4 0.5 0.5 0.8 0.5 0.6 0.8
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.7 -0.2 1.3 -0.4 0.4 0.1 -0.5 0.9 0.2 0.5 0.5 0.5 0.2 0.5 1.3
Qualifications: CSEs or equivalent 0.9 1.2 4.2 -0.8 0.0 -1.3 0.6 0.1 0.4 -0.1 -2.0 -1.2 -1.2 -1.4 -2.0 -0.9 -0.7
Serious illness, injury or assault to yourself 0.3 0.4 2.3 -0.1 0.6 -0.3 0.0 0.4 -1.5 -0.3 -0.5 -0.7 -0.6 -0.2 -1.0 -0.0 0.2
High blood pressure 0.3 0.8 5.5 1.5 -0.8 -0.4 -0.6 -0.3 0.2 -2.3 1.1 0.3 0.3 0.3 0.4 -0.8 -0.2
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.9 0.1 0.1 -0.3 0.5 1.0 -0.2 1.2 -1.7 -0.7 -0.7 -1.6 -1.5 0.0 0.5
Multivitamins +/- minerals 0.9 1.1 4.7 0.6 -0.3 0.5 0.9 1.9 0.3 0.4 2.2 0.1 0.2 1.1 1.4 -1.4 -0.4
Stomach or abdominal pain in last month 0.4 0.5 3.1 -0.1 0.8 -0.9 0.4 0.2 -1.8 0.3 -0.6 -0.4 -0.4 -0.9 0.0 -0.4 0.9
Supplements: Glucosamine 0.4 0.6 2.4 -1.0 0.8 -0.1 -1.2 -1.2 -1.5 -0.4 0.7 -0.2 -0.2 0.5 0.1 0.0 0.1
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 2.0 -0.2 0.5 -0.9 -0.1 -0.6 -1.1 -0.2 -0.6 -0.6 -0.6 -1.0 -0.6 -1.4 0.4
Medication: Atenolol 1.1 1.4 2.8 -0.9 -0.8 -1.5 0.1 -0.1 -1.1 -1.3 -0.6 -1.4 -1.4 -1.7 -1.2 -1.6 -1.3
Medication: Levothyroxine sodium 1.7 2.8 7.4 1.6 -1.2 2.0 1.6 1.3 -0.1 0.8 -0.6 2.3 2.3 1.3 1.4 2.0 2.7
Sitting height 2.1 15.2 43.8 -3.7 -3.3 -4.1 -1.7 -1.3 -0.5 -4.7 -1.6 -4.3 -4.3 -2.5 -5.3 -5.2 -6.6
Chronic bronchitis/emphysema (father) 1.8 2.1 4.8 1.3 0.7 1.6 -1.1 0.7 1.9 0.8 1.0 1.6 1.6 2.2 1.6 1.6 1.7
High blood pressure (mother) 0.2 0.3 1.0 -0.8 -1.0 -0.6 0.5 -0.1 -0.9 0.4 -0.5 0.2 0.2 -0.3 -0.5 0.2 0.1
Body mass index (BMI) 0.8 3.2 9.7 -0.9 3.1 -2.2 -1.9 -1.0 -1.6 -2.2 1.4 -2.1 -2.1 0.9 -0.3 -2.3 -0.8
Impedance of leg (left) 3.2 15.6 30.0 4.3 -3.2 4.1 5.5 3.1 3.7 5.4 -3.6 4.4 4.4 -0.8 1.6 4.6 3.9
Leg predicted mass (left) 2.9 15.4 31.0 -4.1 0.6 -4.3 -4.9 -2.7 -2.5 -5.6 2.3 -4.5 -4.5 0.0 -2.8 -5.4 -5.4
Trunk fat mass 0.5 2.2 7.6 -0.2 -0.1 -1.7 -1.0 -0.5 -0.2 -2.6 1.4 -1.6 -1.5 0.3 -0.6 -2.8 -2.4
Waist circumference 0.2 0.7 1.8 0.5 1.4 -0.8 -1.0 -0.6 0.2 -1.0 1.1 -0.6 -0.5 1.2 0.4 -1.2 -0.3
Number of incorrect matches in round 0.5 0.9 5.0 -1.4 2.2 -0.8 0.0 -0.1 -1.2 0.5 -0.4 -0.9 -0.9 -0.3 -0.5 -0.5 0.4
Past tobacco smoking 0.6 1.0 4.4 -0.7 -0.2 -0.8 1.2 -1.1 -0.7 1.3 -2.1 -0.4 -0.5 -1.1 -1.5 0.5 0.5
Alcohol usually taken with meals 0.3 0.5 2.1 -1.2 -1.3 -0.7 0.7 -0.3 -1.4 -0.3 0.4 -0.0 -0.0 -0.5 -0.1 0.0 -0.1
Nervous feelings 0.3 0.5 1.5 0.1 -1.1 1.0 0.0 1.2 -0.3 0.4 1.0 0.6 0.6 0.9 0.9 0.2 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.7 3.1 0.5 1.8 0.2 1.1 -0.1 0.5 1.4 -0.5 0.6 0.6 0.2 0.3 0.5 1.3
Hearing difficulty/problems with background noise 0.5 0.8 1.6 1.3 -0.7 0.8 -0.2 -1.2 1.0 -0.9 1.2 0.7 0.7 1.2 1.2 -0.7 -0.4
Hair/balding pattern: Pattern 2 0.3 0.4 1.7 0.9 -0.2 1.3 0.6 1.0 -0.1 0.4 -0.7 0.7 0.7 0.1 -0.0 0.5 0.6
Had menopause 0.3 0.4 2.2 -0.4 0.6 -0.2 -0.1 -1.5 0.2 -0.2 1.4 -0.4 -0.4 -0.2 0.4 -0.5 -0.6
Had other major operations 1.4 1.7 8.8 0.9 0.2 1.4 1.5 3.0 0.2 2.3 0.0 0.7 0.6 -0.4 1.0 0.9 1.5
Forced vital capacity (FVC) 1.2 4.6 10.9 -3.2 -0.3 -2.8 -2.5 -1.1 -0.1 -1.6 -0.3 -2.5 -2.5 -0.7 -2.6 -2.4 -3.3
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 6.8 0.9 -0.1 0.7 2.3 2.6 -0.1 1.1 -0.9 0.1 0.0 -0.2 -0.1 0.4 0.5
Ever unenthusiastic/disinterested for a whole week 2.6 3.2 10.8 1.2 0.9 1.9 0.5 1.2 1.2 3.3 0.8 1.9 1.8 1.5 2.3 2.3 2.1
Qualifications: None of the above 0.2 0.4 2.5 0.5 1.6 0.1 0.3 -0.1 -0.1 0.3 -0.0 -0.5 -0.5 0.7 0.2 -1.1 0.1
Financial difficulties in last 2 years 1.2 1.6 4.2 2.1 0.7 1.2 -0.1 0.7 1.4 1.1 -0.4 1.2 1.2 2.0 1.1 1.3 1.8
Mouth/teeth dental problems 4.3 6.6 12.2 1.7 -3.3 3.5 2.8 1.4 2.1 3.0 -0.1 3.4 3.4 0.1 2.3 3.2 2.3
Heart attack 0.3 0.4 2.5 0.0 -0.0 0.2 1.0 1.6 0.1 -0.0 0.1 -0.7 -0.7 -0.2 -0.3 -0.4 -0.4
Allergy 0.5 1.2 3.3 -1.5 0.9 -0.9 -0.4 -1.8 -0.6 -1.3 0.9 -0.9 -1.0 -0.6 0.3 -1.6 -1.4
Pain all over the body in last month 0.2 0.2 0.9 -0.1 -0.7 -0.3 -0.1 -0.5 0.5 -0.4 0.7 -0.2 -0.1 0.9 -0.1 -0.1 -0.8
Diabetes (self-reported) 1.6 2.4 6.6 2.6 0.7 1.6 1.1 2.4 0.9 1.3 -0.1 1.3 1.3 1.6 1.3 1.1 2.5
Hayfever/allergic rhinitis (self-reported) 3.7 4.9 18.5 1.8 1.6 2.5 -0.1 2.2 0.7 4.3 -0.1 2.0 2.0 2.1 1.9 2.9 2.9
Medication: Ramipril 0.4 0.5 1.8 0.9 -0.3 0.5 0.3 1.3 -0.5 -0.6 0.6 0.7 0.7 0.9 0.5 0.3 0.5
Medication: Simvastatin 0.3 0.5 2.0 0.4 -0.7 0.0 0.1 0.3 -0.7 -0.9 0.5 -0.8 -0.8 -0.5 -0.0 -1.4 -1.1
Fluid intelligence score 0.3 0.7 4.9 -0.6 -2.2 -0.2 -0.5 -0.0 -1.1 -0.7 1.2 0.3 0.3 -0.3 0.4 0.5 -0.7
Illnesses of siblings 0.5 0.7 5.0 -1.0 -2.2 -0.1 0.3 -0.5 -1.2 0.8 -0.3 -0.1 -0.2 -0.7 -0.5 0.3 -0.2
Neuroticism score 0.4 0.9 3.0 0.2 -0.5 0.8 1.0 1.7 -0.4 0.6 1.4 0.5 0.5 1.3 1.6 -0.7 0.2
Weight 1.6 7.7 17.6 -2.3 0.9 -3.3 -3.0 -1.8 -1.5 -4.0 1.7 -3.2 -3.2 0.3 -1.8 -4.2 -3.8
Impedance of arm (right) 1.5 7.0 17.5 3.7 -4.2 2.9 2.9 1.6 3.5 2.1 -0.7 3.4 3.3 -0.7 1.8 1.7 0.9
Arm fat percentage (right) 0.2 0.8 2.6 1.0 1.2 -0.9 -0.2 -0.1 0.0 -1.4 1.1 -0.6 -0.5 0.6 0.6 -1.6 -0.5
Trunk fat-free mass 2.8 15.9 33.2 -5.0 0.1 -4.2 -4.3 -2.7 -2.8 -5.5 1.9 -4.6 -4.6 -0.0 -3.4 -5.1 -5.8
Hip circumference 2.3 10.1 16.7 -3.5 2.1 -4.1 -3.3 -2.3 -2.8 -3.6 1.2 -4.1 -4.0 -0.3 -2.3 -4.1 -3.8
Time employed in main current job 2.1 2.5 5.2 2.3 0.8 1.4 -0.1 0.1 1.6 1.9 0.1 1.8 1.8 1.4 2.0 1.7 2.3
Alcohol intake versus 10 years previously 0.2 0.3 0.9 0.6 0.8 0.3 0.6 0.2 0.9 0.9 0.7 -0.1 -0.1 -0.7 0.7 -0.2 -0.0
Father’s age at death 0.7 1.0 3.1 0.3 1.0 0.6 -0.1 -0.3 -0.5 0.6 1.0 1.3 1.3 0.9 1.2 1.1 1.8
Worrier / anxious feelings 0.6 1.2 4.1 1.0 -0.6 1.1 -0.6 2.0 1.1 0.8 0.9 0.9 0.9 1.4 1.7 0.3 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 2.8 -0.2 1.7 -0.6 -0.9 0.1 -1.4 0.0 -0.5 -0.7 -0.7 0.3 -0.2 -0.6 0.6
Falls in the last year 0.3 0.4 1.4 0.9 0.9 0.3 1.2 -0.3 0.1 -0.8 -0.4 0.1 0.1 0.7 -0.4 -0.4 0.9
Hair/balding pattern: Pattern 3 0.2 0.3 1.0 0.2 -0.7 -0.3 -1.0 -0.9 -0.0 -0.8 0.7 0.3 0.3 0.1 0.5 0.6 -0.0
Number of live births 1.4 2.0 6.0 -1.0 -0.8 -1.0 0.4 -1.2 0.3 -2.1 0.2 -1.7 -1.7 -1.4 -1.3 -2.1 -2.4
Forced expiratory volume in 1-second (FEV1) 1.3 4.5 10.2 -3.2 -0.3 -2.9 -1.7 -1.3 -0.5 -1.3 -1.1 -2.6 -2.6 -1.2 -2.9 -2.1 -2.9
Pulse rate 1.7 2.8 7.8 2.0 0.3 1.7 1.8 1.9 2.3 0.9 -2.2 1.3 1.3 0.4 -0.1 2.8 1.9
Happiness 0.7 0.9 3.0 -0.0 1.5 -0.7 -0.1 0.0 -1.3 1.1 -1.7 -0.7 -0.7 -1.2 -0.6 0.2 1.1
Noisy workplace 0.8 1.0 2.3 0.4 -0.9 1.3 1.3 1.1 0.0 1.5 0.3 1.1 1.1 -0.8 1.1 0.9 1.1
Qualifications: A levels/AS levels or equivalent 0.5 1.2 3.4 -0.6 -0.2 -1.0 -1.3 -0.7 -1.0 -1.8 -0.6 -1.1 -1.1 -1.6 -1.4 -0.7 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.9 -0.6 -0.2 0.6 -0.3 -0.3 0.9 -1.0 -0.1 0.3 0.2 -0.4 -0.4 0.5 -0.0
Mouth/teeth dental problems: Dentures 1.7 2.8 9.1 -0.5 0.3 -1.5 -1.6 -0.3 -1.5 -1.9 1.5 -2.1 -2.1 -0.2 -0.5 -3.0 -2.8
Asthma 1.3 2.6 5.7 2.4 -1.0 1.7 0.3 2.3 1.5 1.1 0.8 1.8 1.9 2.0 1.7 1.4 1.5
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.6 5.4 0.4 1.1 1.5 2.0 0.9 -0.5 2.3 -1.1 0.9 0.9 0.3 0.5 0.9 2.1
Medication: Cholesterol lowering 0.5 0.8 2.4 1.5 -0.7 1.0 1.5 1.2 -1.1 -0.3 -0.0 0.7 0.6 0.1 0.7 0.0 0.7
Depression (self-reported) 0.7 0.8 2.2 0.8 1.4 -0.9 -0.7 0.7 -0.2 -0.8 -1.5 -0.9 -0.8 -0.6 -1.1 -0.7 0.4
Medication: Lansoprazole 1.6 1.8 5.3 1.2 -1.3 1.0 -0.2 -1.2 1.9 -1.6 1.3 1.1 1.1 2.3 1.4 0.9 0.9
Prospective memory result 1.0 1.2 2.6 -1.3 1.6 -0.8 -0.2 0.6 -1.4 -0.9 -0.9 -1.4 -1.4 -0.9 -1.3 -0.9 -1.0
Lung cancer (father) 0.5 0.6 1.8 -0.3 -0.9 1.2 0.6 0.2 -0.2 -0.4 1.4 0.6 0.6 1.2 0.8 0.9 -0.7
Illnesses of mother 0.4 0.5 1.0 -0.5 -0.0 -0.6 -0.3 -1.0 -0.5 -0.5 -0.9 -0.8 -0.8 -0.8 -1.0 -0.5 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.7 16.2 -4.0 -0.2 -3.5 -1.4 -1.4 -1.4 -0.5 -0.9 -3.1 -3.1 -0.9 -2.9 -2.5 -3.1
Pulse wave Arterial Stiffness index 2.2 2.5 7.7 1.3 -0.7 2.1 0.1 -0.1 2.8 0.3 2.3 1.7 1.6 1.2 2.0 1.9 1.1
Impedance of arm (left) 1.4 6.6 17.2 3.7 -4.1 2.8 3.0 1.4 3.2 2.0 -0.9 3.2 3.1 -0.9 1.6 1.7 1.0
Arm fat mass (right) 0.7 2.7 7.9 -0.5 1.6 -2.1 -1.5 -0.8 -0.7 -2.6 1.4 -1.9 -1.8 0.5 -0.5 -2.8 -1.8
Trunk predicted mass 2.7 15.6 32.7 -4.9 -0.0 -4.2 -4.2 -2.6 -2.7 -5.5 1.9 -4.5 -4.5 -0.1 -3.3 -5.1 -5.7
Standing height 1.3 13.2 50.1 -3.6 -4.8 -2.9 -2.7 -2.1 -0.0 -4.6 0.9 -2.9 -3.1 -1.6 -3.4 -4.9 -7.1
Length of working week for main job 0.7 0.8 2.3 1.1 1.5 0.2 -0.6 0.4 0.4 1.2 0.7 0.5 0.6 1.1 1.4 0.5 1.0
Exposure to tobacco smoke at home 0.9 1.0 2.2 -0.8 1.1 -1.0 -0.8 -0.0 -0.8 -0.1 -1.3 -1.5 -1.4 -0.8 -1.4 -1.0 -0.8
Breastfed as a baby 0.6 0.8 3.1 -1.1 -1.2 0.1 -0.8 -0.2 -1.8 -0.7 1.5 -0.2 -0.2 0.2 0.5 -0.5 -1.0
Tense / ‘highly strung’ 0.6 1.0 3.6 -0.4 0.8 -0.4 1.7 1.9 -1.6 1.4 -0.2 -0.6 -0.6 -0.2 0.3 -0.9 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.4 0.6 -0.2 0.3 0.9 0.0 -0.1 0.7 -1.2 0.7 0.7 0.4 0.1 0.8 0.7
Hair/balding pattern: Pattern 4 0.4 0.9 2.0 -1.4 1.2 -0.7 1.1 -0.4 -0.3 0.8 0.9 -0.7 -0.8 1.1 0.5 -1.4 -1.2
Birth weight of first child 0.7 1.3 6.0 -0.7 -1.0 -1.1 -2.4 -0.1 -0.6 -1.7 0.6 -0.7 -0.7 -0.2 -0.9 -1.1 -1.5
Peak expiratory flow (PEF) 0.8 1.8 5.2 -1.3 -1.0 -1.1 -0.1 -0.1 -0.4 0.6 -2.1 -1.4 -1.4 -2.2 -2.3 -0.7 -1.4
Pulse wave reflection index 1.7 2.1 7.0 1.5 0.2 1.6 -0.3 0.6 2.1 0.9 2.6 1.3 1.3 1.1 2.2 0.6 1.4
Ever highly irritable/argumentative for 2 days 0.2 0.2 1.4 -0.2 -0.1 0.6 0.3 0.9 -0.3 1.2 0.1 0.1 0.0 0.1 0.6 0.0 -0.1
Loud music exposure frequency 1.4 1.5 4.4 0.6 0.5 1.0 1.2 1.3 0.5 1.1 1.7 1.3 1.3 2.1 1.7 0.6 1.1
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.8 -1.3 0.0 -1.0 -2.0 -0.7 -1.9 -0.9 -0.2 -1.1 -1.1 -0.5 -0.7 -0.5 -1.0
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 13.2 -0.9 3.6 -2.2 -0.8 -0.2 -1.5 -0.4 -1.4 -2.2 -2.1 -0.7 -2.1 -1.9 -0.4
Blood clot in the leg (DVT) 0.4 0.5 1.8 -0.1 0.3 -1.1 -0.9 -0.1 -0.4 -0.7 -0.6 -0.9 -0.8 0.1 -1.3 -0.9 -0.6
Medication: Paracetamol 0.4 0.7 3.1 -0.7 1.7 -0.8 -0.6 -0.1 -1.2 0.3 -1.4 -0.6 -0.6 -0.2 -0.7 -0.3 1.0
Headache pain in last month 0.9 1.5 7.6 0.5 0.1 0.0 1.8 1.5 0.3 0.6 -2.8 -0.3 -0.3 -1.8 -1.7 0.6 1.0
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.9 -1.7 0.2 -0.6 -0.6 -1.1 0.8 0.6 0.1 -0.3 -0.3 -0.4 -0.2 0.4 -0.8
Glaucoma (self-reported) 0.7 0.9 2.0 1.3 -1.1 0.7 1.4 -0.5 0.3 1.2 -0.9 1.2 1.2 -0.5 0.4 0.8 0.8
Gout (self-reported) 0.4 0.5 3.0 0.1 -0.3 0.1 -0.4 -1.0 -0.2 -0.4 1.7 0.4 0.5 0.8 1.3 0.1 0.1
Hypothyroidism/myxoedema (self-reported) 0.7 1.3 3.7 0.7 -0.8 0.9 1.8 0.4 -0.3 -0.0 -1.2 1.6 1.5 0.4 0.1 1.7 1.9
Medication: Amlodipine 0.6 0.8 3.4 1.1 -1.8 1.0 0.5 0.1 -0.3 -0.8 1.1 1.0 1.0 0.7 0.6 0.2 0.2
Medication: Ventolin 100micrograms inhaler 0.3 0.4 2.3 1.5 -0.8 0.5 -0.5 0.7 1.0 0.4 -0.1 0.1 0.2 0.8 0.0 0.0 -0.2
Birth weight 1.0 2.2 9.9 0.7 -3.1 1.3 0.7 -0.8 1.4 0.1 1.7 1.7 1.7 1.8 1.3 1.2 -0.3
Chronic bronchitis/emphysema (mother) 0.6 0.8 2.9 -0.4 -0.7 -0.5 0.1 -0.5 0.3 -1.1 0.4 -1.0 -1.1 -1.0 -0.5 -1.2 -1.7
High blood pressure (siblings) 0.4 0.6 5.6 0.6 2.4 -0.3 -1.0 -0.3 0.5 -0.7 0.2 0.1 0.1 0.4 0.5 -0.1 0.7
Forced vital capacity (FVC), Best measure 1.4 5.3 14.2 -3.8 -0.7 -3.1 -2.2 -1.4 -0.8 -1.1 -0.3 -2.8 -2.8 -0.3 -2.7 -2.5 -3.4
Body fat percentage 0.1 0.4 1.8 1.4 0.5 -0.6 0.3 0.3 0.2 -0.9 0.5 -0.4 -0.3 0.4 0.4 -1.2 -0.3
Leg fat percentage (right) 0.1 0.5 2.3 1.1 1.5 -0.2 0.8 0.5 -0.1 0.7 -0.0 -0.0 0.1 0.7 0.7 -0.1 1.0
Arm fat-free mass (right) 2.6 13.3 24.0 -4.3 0.8 -4.1 -4.1 -2.3 -2.7 -4.8 1.5 -4.5 -4.5 -0.0 -3.2 -4.7 -4.9
Exposure to tobacco smoke outside home 1.1 1.5 6.7 -1.3 0.9 -1.1 -0.2 0.0 -0.4 -0.4 -0.3 -1.7 -1.7 -0.7 -1.1 -2.6 -1.4
Comparative body size at age 10 0.5 1.3 5.3 -0.1 1.6 -0.9 -1.7 -1.2 0.6 -2.3 0.7 -0.7 -0.7 1.9 -0.5 0.1 -0.0
Number of full brothers 0.8 1.0 3.3 1.2 -0.2 1.1 -0.2 1.3 -0.7 1.1 0.7 0.7 0.7 1.8 1.8 0.1 0.3
Worry too long after embarrassment 0.3 0.5 2.9 -0.1 -1.7 -0.1 0.8 -0.1 -0.2 -0.5 1.3 -0.1 -0.1 0.1 0.5 -1.1 -0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.2 0.2 1.2 -0.6 -1.5 -0.1 -1.0 -0.7 -0.1 -0.3 -0.3 1.0 0.2 -0.3 -0.0
Wheeze or whistling in the chest in last year 0.3 0.5 2.4 1.6 1.3 0.4 -0.6 1.3 0.0 0.2 0.2 -0.2 -0.1 0.6 0.4 -0.4 0.6
Number of children fathered 1.8 2.1 5.4 -1.8 -0.7 -1.6 -0.8 -0.1 -1.6 -0.7 0.3 -1.8 -1.8 -0.6 -1.3 -2.3 -2.3
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.7 -1.0 -0.6 -0.9 1.3 -0.1 0.1 -0.2 0.6 -0.4 -0.4 -0.4 0.1 -0.9 -0.9
Age at first live birth 0.2 0.3 0.9 -0.3 -0.9 0.2 -0.9 -0.3 0.1 0.3 0.6 0.6 0.7 0.6 0.4 0.8 0.3
Pulse wave peak to peak time 2.6 3.0 7.8 -1.5 0.2 -2.4 -0.2 -0.0 -2.8 -0.4 -2.3 -1.9 -1.8 -1.4 -2.2 -2.2 -1.7
Health satisfaction 0.5 0.6 2.8 0.6 1.7 -0.0 -0.5 0.0 -0.3 -0.7 -1.0 -0.1 -0.0 0.1 -0.3 1.0 1.4
Shortness of breath walking on level ground 0.6 0.7 1.7 -0.9 0.4 -1.1 -0.3 -0.4 -0.1 -0.6 -0.8 -1.1 -1.2 -0.3 -1.3 -0.6 -1.0
Qualifications: College or University degree 0.2 0.7 3.1 0.2 -1.8 1.1 0.2 -0.1 0.5 -0.6 0.6 1.1 1.1 0.2 0.6 1.3 -0.1
Eye problems/disorders: None of the above 0.3 0.4 2.1 -0.6 1.4 -0.2 -0.8 -0.8 -0.2 -0.3 0.9 0.1 0.1 0.3 0.3 0.4 0.4
Mouth/teeth dental problems: Loose teeth 1.3 1.6 4.1 -0.7 0.6 -1.8 -1.8 -1.3 -0.1 -2.0 0.1 -1.3 -1.3 -0.4 -1.4 -1.1 -1.5
Emphysema/chronic bronchitis 0.7 0.8 2.4 1.6 -0.5 0.7 -0.2 0.9 1.2 0.2 1.0 1.0 1.0 0.6 0.9 1.1 0.4
Medication for pain relief, constipation, heartburn 0.5 0.8 2.9 -0.6 -1.1 -1.2 -0.2 -1.7 0.9 -0.9 -0.1 -0.1 -0.1 -1.1 -0.6 0.4 -1.4
Neck or shoulder pain in last month 0.2 0.3 1.4 1.2 0.2 0.9 0.0 1.0 0.4 -0.0 -0.5 0.1 0.1 0.1 -0.1 0.4 0.3
Medication: Blood pressure 0.3 0.5 2.5 1.6 -0.1 0.2 0.2 0.9 -0.6 -1.5 -0.3 -0.2 -0.3 -0.2 -0.3 -1.1 0.5
Angina (self-reported) 0.4 0.5 1.6 -0.1 -0.0 -0.2 0.5 0.2 -1.3 -0.1 1.0 -0.6 -0.7 0.2 0.4 -1.3 -1.1
Migraine (self-reported) 0.1 0.1 0.4 0.4 -0.6 -0.1 -0.1 0.2 -0.4 -0.3 0.1 0.4 0.4 0.0 0.4 0.5 0.7
Medication: Ibuprofen 1.3 1.5 5.0 0.6 1.2 1.8 1.0 0.6 0.1 2.2 -0.2 1.3 1.3 0.9 1.4 0.9 1.8
Medication: Allopurinol 0.6 0.7 2.9 0.2 -1.1 0.5 -0.9 -1.7 0.3 -1.3 1.2 0.7 0.7 -0.3 0.7 0.6 0.3
Medication: Omeprazole 1.3 1.6 6.1 1.4 0.2 1.2 -0.6 0.7 0.9 -0.5 2.1 0.9 0.9 2.5 1.9 -0.2 0.6
Medication: Seretide 50 evohaler 0.8 0.9 2.8 1.4 -0.9 1.6 0.3 1.7 -0.0 -0.0 1.1 0.7 0.7 1.2 1.0 0.1 0.5
Mean time to correctly identify matches 0.1 0.3 1.0 0.5 0.3 0.8 1.0 0.2 0.6 0.8 -0.2 0.1 0.1 -0.5 0.1 -0.0 0.4
Heart disease (mother) 0.7 0.8 3.2 1.1 -0.6 1.1 1.8 0.1 0.7 0.8 0.4 1.1 1.1 0.5 0.8 0.9 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.6 0.5 0.5 -0.7 -0.4 -0.9 1.6 -1.4 -0.7 -0.4 -0.5 -0.4 -0.7 -0.8 -0.8
Whole body fat mass 0.5 2.0 6.3 -0.3 0.6 -1.8 -1.1 -0.6 -0.3 -2.4 1.1 -1.6 -1.6 0.2 -0.6 -2.5 -2.0
Leg fat mass (right) 0.3 1.0 2.8 -0.3 1.4 -1.3 -0.8 -0.2 -0.5 -1.3 0.6 -1.3 -1.3 0.6 -0.4 -1.7 -0.8
Arm predicted mass (right) 2.6 13.2 26.2 -4.2 0.5 -4.0 -4.0 -2.1 -2.6 -5.1 1.5 -4.4 -4.4 0.2 -3.3 -4.7 -4.9
Pulse rate, automated reading 0.7 2.1 6.9 1.7 1.6 1.6 0.2 0.6 1.2 1.3 -1.3 1.2 1.2 0.8 0.3 2.5 2.6
Alcohol intake frequency. 0.5 1.3 5.2 0.6 0.6 -0.6 2.3 0.6 -1.5 0.9 -2.0 -0.8 -0.8 0.3 -1.2 -0.3 1.0
Comparative height size at age 10 1.4 8.0 28.5 -1.9 -2.4 -1.8 -3.1 -2.1 -0.9 -4.1 0.7 -2.5 -2.6 -0.9 -2.7 -4.1 -5.3
Number of full sisters 0.7 0.8 3.2 1.3 -1.5 1.1 0.3 1.8 0.8 0.8 0.3 0.2 0.3 0.6 0.6 -0.4 -0.8
Suffer from ‘nerves’ 0.1 0.1 0.6 0.2 -0.3 0.4 -0.7 0.8 0.1 -0.1 0.1 0.2 0.2 0.5 0.5 0.1 0.1
Overall health rating 0.2 0.4 1.2 1.1 0.9 -0.4 -0.3 0.5 0.1 -0.9 -0.7 -0.3 -0.3 1.1 -0.4 0.0 0.8
Chest pain or discomfort 0.4 0.6 2.4 0.9 0.5 -0.7 0.4 0.5 0.0 -1.0 -0.1 -0.8 -0.8 0.9 -0.6 -1.6 -0.4
Had major operations 0.2 0.3 1.4 0.4 0.3 -0.1 0.9 -0.4 0.1 -0.1 -0.7 0.3 0.3 0.2 -0.2 0.4 1.2
Age at last live birth 0.2 0.3 3.2 -0.4 -0.4 -0.0 -1.8 -0.4 -0.6 -0.2 0.1 -0.2 -0.2 0.3 -0.3 -0.1 -0.5
Family relationship satisfaction 0.2 0.3 1.5 -0.1 -0.0 -0.1 0.1 0.7 -0.3 0.4 -1.2 0.0 0.0 -0.6 -0.2 0.6 0.8
Leg pain on walking 0.7 0.9 4.4 -1.1 -0.3 -0.6 -0.7 0.3 -2.1 0.5 0.3 -1.2 -1.2 -0.3 -0.6 -0.9 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 4.0 0.0 -2.0 -0.2 -0.1 1.6 -1.1 -1.3 0.5 -0.8 -0.8 -0.2 -0.5 -1.1 -1.0
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.8 0.6 -0.6 0.7 -0.3 0.3 0.6 0.9 0.8 0.3 0.3 1.3 0.8 -0.3 -0.2
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.4 -0.4 0.3 -1.1 -0.0 -0.2 -0.1 -0.3 0.2 -0.7 -0.7 -1.2 -0.1 -0.6 -0.6
Medication: Aspirin 0.4 0.5 3.8 -0.2 0.1 -0.1 -0.1 0.3 -1.9 0.0 0.6 -0.8 -0.8 -0.1 -0.1 -1.1 -0.4
Supplements: Vitamin C 0.3 0.4 1.5 0.6 -0.3 0.9 0.6 0.3 -0.4 1.2 0.2 0.4 0.4 0.0 1.1 0.3 0.4
Knee pain experienced in last month 0.3 0.4 1.6 0.1 1.2 -0.2 0.6 0.0 0.0 1.0 -1.1 0.0 0.1 -0.1 -0.2 0.4 1.3
Hypertension (Self-reported) 0.4 1.1 7.0 1.8 -0.6 -0.4 -0.7 -0.1 0.2 -2.6 1.4 0.3 0.3 0.7 0.4 -1.0 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.5 -0.6 -0.2 0.1 -0.2 0.5 -0.3 -0.2 -0.7 -0.5 -0.5 0.3 0.0 -0.1 0.1
Illnesses of father: Heart disease 1.6 2.2 7.1 -0.2 -0.4 -1.5 -0.3 0.1 -0.8 -0.6 -2.5 -2.0 -2.0 -2.1 -2.7 -1.1 -1.0
Illnesses of siblings: Diabetes 1.0 1.2 3.2 0.9 1.4 1.2 -0.3 1.1 1.8 -0.9 1.8 0.3 0.3 1.7 1.0 -0.3 0.3
Smoking status: Previous 0.6 0.9 4.0 0.2 0.1 0.2 -0.7 1.1 0.3 -1.3 2.0 0.2 0.3 1.3 1.4 -1.2 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 5.2 -1.6 -1.6 -1.5 -1.0 -0.8 0.6 -1.3 -0.4 -1.5 -1.5 -1.2 -1.9 -1.4 -2.3
Whole body fat-free mass 2.9 16.8 33.4 -4.7 0.3 -4.4 -4.8 -2.6 -2.8 -5.8 2.1 -4.7 -4.7 -0.0 -3.3 -5.4 -5.8
Leg fat-free mass (right) 3.1 16.4 36.2 -4.0 0.5 -4.3 -5.4 -2.6 -2.6 -6.0 2.4 -4.5 -4.5 0.0 -3.0 -5.5 -5.5
Arm fat percentage (left) 0.2 0.8 2.7 1.1 1.2 -1.0 -0.3 0.1 -0.0 -1.4 1.2 -0.7 -0.6 0.7 0.6 -1.6 -0.5
Average weekly red wine intake 0.4 0.5 1.2 -0.7 -0.1 -0.5 -0.6 -0.9 1.0 -1.1 0.0 -0.6 -0.7 -0.9 -0.6 -0.8 -0.8
Handedness (chirality/laterality): Left-handed 0.4 0.5 3.5 -0.6 -1.9 -0.4 -0.1 -0.7 -0.6 0.2 0.7 0.1 0.0 -0.4 0.7 -0.5 -0.8
Mood swings 0.2 0.4 1.8 0.3 1.2 0.2 0.4 0.8 -0.2 0.4 -0.0 0.3 0.3 1.3 0.5 0.1 1.0
Loneliness, isolation 0.2 0.2 1.4 -0.2 1.2 0.3 -0.5 0.1 0.7 -0.5 -0.1 -0.2 -0.3 -0.4 -0.1 -0.5 0.3
Long-standing illness, disability or infirmity 0.3 0.4 2.0 1.3 -0.8 0.5 0.6 1.4 -0.1 -0.1 -0.8 -0.2 -0.1 0.1 -0.2 -0.5 0.4
Ever had bowel cancer screening 1.0 1.1 4.5 -1.1 -0.6 -0.4 -0.8 -0.8 -0.8 -2.1 1.3 -0.8 -0.7 0.7 -0.3 -1.4 -1.6
Diabetes diagnosed by doctor 2.2 3.7 9.0 2.6 0.1 2.2 2.8 3.0 1.0 1.5 -0.4 1.8 1.8 1.1 1.1 1.6 2.7
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.3 4.3 1.6 2.1 1.0 -0.9 1.0 1.3 -0.2 -0.9 1.0 1.0 0.1 0.2 1.1 1.7
Friendships satisfaction 1.9 2.3 5.9 -0.7 2.4 -1.4 -1.8 -0.9 -0.3 -1.6 -1.9 -1.9 -1.9 -1.0 -1.8 -1.4 -0.4
Qualifications: nursing, teaching 1.0 1.5 4.2 -1.4 0.5 -1.1 -0.9 -1.0 -1.0 -1.2 -1.1 -1.2 -1.3 -2.1 -1.9 -0.5 -1.0
Commuting to job workplace: Walk 0.4 0.5 2.2 1.1 0.6 0.4 0.7 -0.1 1.5 -0.8 -0.1 0.5 0.5 -0.6 -0.2 0.7 0.5
Eye problems/disorders: Cataract 0.8 0.9 3.9 -0.7 -2.0 -0.2 0.6 0.7 -1.1 -0.4 0.1 -1.0 -1.0 -0.2 -0.4 -1.3 -1.5
Mouth/teeth dental problems: Mouth ulcers 1.7 2.7 5.2 -2.2 1.3 -2.2 -2.3 -1.9 -0.7 -2.2 0.7 -1.6 -1.6 0.2 -1.1 -1.7 -1.4
Medication for cholesterol 0.7 1.0 4.3 -0.9 -0.5 -0.5 -0.6 -0.1 -2.1 0.6 -1.2 -1.2 -1.2 -0.8 -1.4 -0.6 -0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 3.3 -1.3 -0.8 -0.7 0.4 -0.1 -0.2 -0.4 -0.9 -1.4 -1.5 -1.8 -1.3 -1.5 -1.6
Back pain experienced in last month 0.5 0.7 2.3 -0.4 -0.1 -0.3 0.0 1.3 -1.5 1.3 -1.1 -0.7 -0.7 -0.6 -1.1 -0.4 0.1
Mineral and other dietary supplements 0.5 0.7 1.4 -1.0 0.3 -0.9 -0.2 -0.6 0.2 0.1 -0.4 -1.1 -1.1 -1.1 -0.8 -1.2 -1.2
Breast cancer (self-reported) 0.4 0.5 2.6 0.5 0.6 0.4 1.4 1.6 0.5 0.4 -0.2 0.5 0.5 -0.1 -0.0 0.3 0.8
Asthma (self-reported) 1.3 2.5 5.6 2.4 -0.9 1.6 0.1 2.3 1.4 1.0 1.0 1.7 1.8 2.0 1.7 1.3 1.4
Osteoporosis (self-reported) 0.3 0.3 1.7 0.2 -0.1 -0.2 -0.6 -1.2 0.1 -0.2 -1.3 0.1 0.1 -0.9 -0.4 0.1 0.0
Osteoarthritis (self-reported) 0.6 0.8 4.4 -1.1 2.1 -0.5 -0.2 0.2 -0.4 -0.4 1.5 -0.8 -0.8 0.1 0.4 -0.9 -0.4
Medication: Aspirin 0.3 0.4 3.7 0.0 0.1 0.3 0.3 0.8 -1.9 0.4 0.8 -0.3 -0.3 0.0 0.4 -0.6 -0.1
Medication: Gliclazide 0.8 0.9 3.2 1.1 0.1 1.5 1.8 1.3 -0.2 1.3 -0.6 0.3 0.3 -0.3 -0.0 0.7 1.1
Illnesses of father: None of the above (group 1) 0.8 1.0 4.1 -0.0 -2.0 0.5 1.0 -0.6 -0.2 0.1 1.5 1.2 1.2 1.1 1.5 0.3 0.1
Smoking status: Current 1.1 1.8 5.0 1.7 1.9 1.6 0.3 0.0 1.6 0.5 -0.5 1.0 1.0 0.3 1.0 2.2 2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.3 10.4 -3.2 1.5 -2.8 -1.2 -1.7 -2.2 0.3 -1.1 -2.1 -2.1 -0.5 -2.0 -1.0 -0.9
Whole body water mass 3.0 17.1 34.1 -4.7 0.4 -4.4 -4.9 -2.7 -2.8 -5.8 2.1 -4.8 -4.8 0.0 -3.3 -5.4 -5.8
Leg predicted mass (right) 3.1 16.6 37.3 -4.1 0.5 -4.3 -5.4 -2.6 -2.6 -6.1 2.4 -4.5 -4.5 0.1 -2.9 -5.5 -5.6
Arm fat mass (left) 0.7 2.9 8.3 -0.6 1.4 -2.2 -1.6 -0.9 -0.9 -2.6 1.3 -2.1 -2.0 0.4 -0.7 -2.9 -2.0
Number of self-reported non-cancer illnesses 0.2 0.3 1.1 1.1 0.5 -0.3 0.1 0.7 -0.9 -0.7 -0.3 -0.1 -0.0 0.7 0.3 -0.6 0.7
Average weekly champagne plus white wine intake 1.1 1.6 4.3 -0.6 -0.1 -1.5 -0.2 0.8 -0.4 -2.1 -1.0 -1.3 -1.3 -1.8 -1.9 -0.6 -1.6
Miserableness 0.7 1.1 3.1 -1.4 1.3 -1.0 0.7 -0.6 -1.6 -0.3 -0.6 -1.3 -1.4 -0.5 -0.6 -1.8 -0.1
Guilty feelings 0.5 0.8 1.7 -1.3 1.0 -0.1 -0.4 1.1 -1.1 1.1 1.2 -0.8 -0.7 0.4 0.8 -1.2 -0.5
Wears glasses or contact lenses 0.3 0.4 1.0 -0.4 -0.2 -0.4 0.6 0.5 -0.2 0.6 -0.7 -0.7 -0.7 -1.0 -0.7 -0.7 -0.4
Ever taken oral contraceptive pill 2.2 2.4 6.7 1.6 -0.6 1.6 1.7 1.6 2.6 1.9 -0.3 1.5 1.5 0.8 1.0 1.9 1.6
Hearing aid user 0.9 1.1 3.9 -0.3 -0.1 -0.3 0.9 -0.3 -0.4 -1.6 -1.6 -1.0 -1.0 -1.4 -2.0 -0.7 -0.5
Mother’s age at death 1.3 1.6 6.4 -1.4 1.5 -1.4 -1.2 -1.6 -2.5 -1.2 -0.2 -1.1 -1.2 -0.4 -0.9 -0.9 -0.1
Financial situation satisfaction 2.9 3.6 7.8 1.2 2.6 1.6 0.5 1.8 0.8 1.9 0.4 2.1 2.1 2.6 1.9 2.1 2.8
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.6 -0.5 -1.2 0.0 1.5 0.6 0.6 -0.2 -0.6 -0.7 -0.7 -1.6 -1.0 -0.9 -1.5
Commuting to job workplace: Public transport 0.7 0.8 2.6 -1.0 -0.6 -0.7 -0.9 -0.7 -1.2 -0.9 -1.2 -0.5 -0.5 -1.6 -1.0 0.4 0.0
Eye problems/disorders: Glaucoma 0.7 0.8 3.1 1.6 -0.9 0.5 1.8 0.1 0.2 0.7 -1.3 0.6 0.6 -1.0 -0.2 0.2 1.0
Medication: Blood pressure 0.5 1.0 3.8 -0.1 -0.1 -1.0 -1.0 -0.8 0.7 -1.9 1.9 0.2 0.2 0.5 0.9 -1.0 -0.9
Pain type(s) experienced in last month: Hip pain 0.5 0.6 4.2 -0.1 -0.7 0.4 2.1 0.8 -0.9 0.8 0.6 0.5 0.4 0.7 0.3 -0.2 0.3
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.5 -0.0 -0.9 -0.4 -0.7 -0.4 -1.2 -0.7 0.0 0.0 0.0 -0.0 -0.2 0.1 -0.3
High cholesterol (Self-reported) 0.2 0.4 2.2 0.6 -0.3 0.6 -0.5 -0.2 0.1 -0.5 0.7 0.8 0.8 0.1 1.5 0.1 0.5
Medication: Bendroflumethiazide 0.9 1.4 5.1 -0.4 0.5 -1.4 -1.7 -0.3 0.3 -2.3 0.0 -1.1 -1.1 -1.0 -1.0 -1.5 -1.5
Medication: Paracetamol 0.6 0.9 5.0 -0.7 2.2 -0.5 -0.7 -0.4 -1.5 0.8 -1.2 -0.4 -0.4 0.2 -0.2 -0.1 1.0
Medication: Lisinopril 2.6 3.4 6.3 1.8 -0.8 1.6 1.5 -0.6 2.3 0.7 1.4 2.5 2.5 2.1 2.3 2.2 1.6
Medication: Atorvastatin 0.3 0.4 1.8 0.5 0.3 -0.4 0.2 0.5 -1.4 -1.1 0.2 -0.2 -0.1 0.1 0.6 -0.8 0.1
Illnesses of father: High blood pressure 0.2 0.3 2.0 0.4 1.4 0.6 -0.2 -0.5 0.3 0.3 -0.3 0.2 0.1 -0.4 0.8 0.0 0.5
Alcohol drinker status: Never 0.1 0.1 0.6 0.1 -0.3 0.3 0.8 0.2 -0.5 -0.3 0.1 0.0 0.0 0.5 0.4 0.2 0.4
Ever smoked 0.4 0.7 2.5 1.0 0.1 0.6 -0.7 1.2 0.2 -1.3 1.6 0.3 0.3 0.6 1.1 -0.3 -0.1
Basal metabolic rate 2.7 15.0 29.4 -4.2 0.7 -4.3 -4.4 -2.5 -2.5 -5.4 1.9 -4.5 -4.5 -0.0 -3.1 -5.2 -5.4
Leg fat percentage (left) 0.1 0.5 1.9 1.3 1.4 -0.2 0.5 0.5 -0.2 0.4 0.0 0.0 0.1 0.8 0.7 -0.0 1.1
Arm fat-free mass (left) 2.6 13.3 23.1 -4.3 0.9 -4.3 -4.0 -2.7 -2.7 -4.7 1.3 -4.4 -4.4 -0.2 -3.2 -4.8 -4.8
Number of operations (self-reported) 0.6 0.8 2.9 0.3 1.5 0.5 1.7 0.6 0.1 1.1 -1.1 0.1 0.1 -0.6 -0.1 0.6 1.6
Average weekly beer plus cider intake 0.7 1.1 1.8 1.4 0.1 1.3 0.9 1.2 0.7 -0.2 0.9 1.2 1.2 1.2 1.2 0.8 1.1
Irritability 0.3 0.6 2.3 -0.7 0.3 -0.5 -0.0 0.8 -1.5 -0.6 -0.3 -1.0 -1.0 -0.0 -0.4 -1.0 -0.6
Risk taking 1.0 1.4 3.7 -0.2 1.9 -1.9 0.4 0.3 -1.3 -0.7 -0.7 -1.7 -1.6 -0.3 -1.4 -1.5 -0.3
Ever had prostate specific antigen (PSA) test 1.1 1.2 2.2 1.1 -1.2 1.4 1.5 1.3 0.6 0.2 0.2 1.3 1.3 1.4 1.0 0.8 1.0
Fractured/broken bones in last 5 years 0.7 0.8 3.2 0.3 0.7 0.6 -0.2 -1.4 1.8 0.6 -0.7 0.8 0.8 -0.4 0.1 1.3 1.3
Age started oral contraceptive pill 0.4 0.5 3.9 -0.9 -0.2 -1.2 -0.6 -2.0 0.1 -0.4 0.2 -0.3 -0.3 -0.4 -0.4 0.2 -0.5
Diastolic blood pressure, automated reading 0.7 2.2 9.7 -0.1 3.1 -2.3 -1.7 -0.8 -0.7 -1.4 -1.6 -1.4 -1.4 -0.7 -1.5 -1.1 0.1
Ever depressed for a whole week 2.8 3.4 8.9 1.4 1.0 2.2 1.0 1.3 0.9 2.6 -1.0 2.2 2.1 0.4 1.3 3.0 3.0
Unable to work because of sickness or disability 0.7 0.9 4.7 1.3 -0.0 0.8 2.2 -0.3 0.1 1.4 -0.6 0.7 0.7 0.3 0.5 0.8 1.1
Commuting to job workplace: Cycle 0.6 0.7 2.6 -0.2 -1.6 -1.0 0.8 0.9 -1.1 -0.1 -0.2 -0.7 -0.7 -1.1 -0.7 -0.8 -0.8
Myopia 0.7 1.0 4.6 -2.2 -1.1 -0.6 -0.2 -0.6 0.0 -0.3 -0.7 -1.0 -1.0 -0.6 -1.2 -0.4 -1.6
Vascular/heart problems diagnosed by doctor 0.3 0.7 4.5 -1.1 1.2 0.5 0.7 0.1 0.4 2.1 -0.9 0.0 0.0 -0.1 -0.1 1.0 0.6
Cholesterol lowering medication 0.2 0.3 0.7 0.7 0.4 -0.1 -0.6 -0.2 0.7 -0.8 0.6 -0.2 -0.2 0.2 0.6 -0.7 -0.3
Medication: Omeprazole (e.g. Zanprol) 1.9 2.3 7.1 1.5 0.1 1.6 -0.9 0.5 1.3 -0.5 2.6 1.2 1.2 2.7 2.5 0.1 0.7
Pain experienced in last month 0.3 0.5 1.5 -0.5 1.2 -0.9 -1.2 -0.5 0.6 -1.1 0.7 -0.5 -0.5 0.2 -0.1 -0.6 -0.8
Supplements: Calcium 0.3 0.4 0.9 0.0 -0.7 -0.0 0.7 -0.3 -0.4 -0.4 -0.9 0.7 0.7 -0.8 -0.3 0.9 0.6
Basal cell carcinoma (self-reported) 1.9 2.2 7.7 1.5 -0.6 1.6 2.8 0.4 1.9 0.4 -1.3 1.8 1.7 -0.1 -0.1 2.2 1.5
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.4 -0.1 0.3 0.1 0.8 1.6 -0.1 0.2 -0.1 -0.9 -0.8 -0.3 -0.4 -0.5 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.5 -0.3 0.3 -1.1 -1.0 -0.2 -0.4 -0.9 -0.5 -0.8 -0.8 0.0 -1.2 -0.8 -0.6
Heart disease (siblings) 0.4 0.5 2.0 0.6 0.7 0.9 0.6 -0.4 1.4 -0.3 1.0 0.4 0.4 0.9 0.9 -0.3 -0.1
Alcohol drinker status: Previous 1.8 2.0 4.4 -1.4 -1.4 -1.3 1.8 -1.2 -2.1 -1.8 -0.4 -1.2 -1.2 0.1 -1.9 -1.3 -1.5
Pack years of smoking 0.5 0.7 2.5 0.6 0.5 0.6 1.6 1.0 -0.7 0.2 -1.3 -0.4 -0.4 -1.2 -0.7 -0.4 0.8
Impedance of whole body 2.3 11.6 20.5 4.3 -4.1 3.7 4.5 2.6 3.8 4.0 -2.3 4.0 3.9 -1.0 1.7 3.1 2.4
Leg fat mass (left) 0.3 1.3 3.3 -0.2 1.4 -1.6 -1.1 -0.3 -0.5 -1.6 0.5 -1.5 -1.4 0.5 -0.6 -1.8 -1.0
Arm predicted mass (left) 2.6 13.3 23.6 -4.2 0.9 -4.2 -4.0 -2.5 -2.6 -4.8 1.3 -4.4 -4.4 -0.3 -3.2 -4.8 -4.9