[Hub]/) : Traits : Sitting height : ← →

chr12:14,220,891-15,807,367

Best TWAS P=6.35e-10 · Best GWAS P=3.32e-09 conditioned to 2.17e-08

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C12orf60	0.28	0.25	lasso	4	0.24	2.0e-29	5.3	5.7	1.5e-08	-0.04	0.26	0.74	FALSE
2	GTEx	Artery Tibial	WBP11	0.09	0.06	lasso	2	0.06	3.8e-05	-4.8	5.2	1.7e-07	-0.03	0.34	0.64	FALSE
3	GTEx	Brain Caudate basal ganglia	C12orf60	0.39	0.34	lasso	3	0.32	5.4e-10	5.3	5.1	2.9e-07	-0.04	0.36	0.63	FALSE
4	GTEx	Brain Cerebellum	C12orf60	0.19	0.17	lasso	3	0.13	1.2e-04	5.3	5.5	4.1e-08	-0.06	0.13	0.32	FALSE
5	GTEx	Brain Cortex	C12orf60	0.44	0.28	lasso	3	0.29	1.2e-08	5.3	5.7	1.1e-08	-0.05	0.28	0.65	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	RP11-174G6.5	0.23	0.13	lasso	4	0.11	8.9e-04	-5.5	5.5	3.4e-08	-0.07	0.14	0.39	FALSE
7	GTEx	Brain Putamen basal ganglia	C12orf60	0.33	0.32	lasso	3	0.29	1.5e-07	5.3	5.3	9.8e-08	-0.05	0.21	0.50	FALSE
8	GTEx	Breast Mammary Tissue (Female)	C12orf60	0.19	0.17	lasso	3	0.12	2.6e-04	5.3	5.3	1.0e-07	-0.04	0.13	0.26	FALSE
9	GTEx	Cells Transformed fibroblasts	C12orf60	0.10	0.10	lasso	2	0.09	1.8e-07	5.7	5.8	7.7e-09	-0.06	0.10	0.90	FALSE
10	GTEx	Heart Left Ventricle	C12orf60	0.24	0.23	lasso	5	0.26	7.1e-14	5.3	5.2	1.7e-07	-0.03	0.37	0.63	FALSE
11	GTEx	Muscle Skeletal	C12orf60	0.23	0.10	lasso	4	0.12	1.1e-11	5.3	5.7	1.5e-08	-0.04	0.19	0.80	FALSE
12	GTEx	Nerve Tibial	C12orf60	0.39	0.27	enet	11	0.30	9.6e-22	5.3	5.5	5.1e-08	-0.05	0.31	0.69	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	C12orf60	0.15	0.16	lasso	2	0.13	1.6e-07	5.3	5.6	1.9e-08	-0.05	0.20	0.80	FALSE
14	GTEx	Skin Sun Exposed Lower leg	C12orf60	0.09	0.06	enet	11	0.05	4.0e-05	5.3	5.5	4.5e-08	-0.08	0.21	0.78	FALSE
15	GTEx	Thyroid	C12orf60	0.16	0.10	enet	9	0.12	8.1e-10	5.7	6.1	1.3e-09	-0.08	0.09	0.91	FALSE
16	METSIM	Adipose	C12orf60	0.14	0.10	lasso	4	0.08	1.2e-12	5.3	5.4	7.9e-08	-0.05	0.33	0.67	FALSE
17	METSIM	Adipose	MGP	0.04	0.04	bslmm	359	0.04	6.2e-07	-3.5	5.4	7.2e-08	-0.14	0.99	0.00	FALSE
18	NTR	Blood	ARHGDIB	0.01	0.00	blup	377	0.00	5.6e-02	-3.6	5.2	1.6e-07	-0.34	0.26	0.03	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	WBP11	0.10	0.05	lasso	4	0.06	1.2e-08	-4.8	5.8	8.8e-09	-0.06	0.46	0.54	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	C12orf60	0.26	0.29	lasso	5	0.29	1.9e-37	5.3	5.3	1.4e-07	-0.04	0.32	0.68	FALSE
21	YFS	Blood	H2AFJ	0.05	0.02	bslmm	360	0.03	2.9e-10	-4.8	-6.0	2.2e-09	0.09	0.27	0.73	FALSE
22	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C12orf60	0.17	0.03	blup	56	0.07	2.9e-06	5.7	5.5	3.9e-08	-0.01	0.00	0.99	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C12orf60	0.12	0.07	enet	8	0.07	5.4e-05	5.3	6.0	2.4e-09	-0.03	0.02	0.95	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	C12orf60	0.14	0.14	lasso	4	0.13	2.2e-14	5.3	5.7	1.5e-08	-0.05	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	WBP11	0.03	0.03	blup	57	0.02	2.3e-03	-4.8	5.2	1.7e-07	-0.05	0.09	0.36	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	C12orf60	0.07	0.05	enet	7	0.05	1.5e-06	5.3	5.7	9.4e-09	-0.04	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C12orf60	0.05	0.05	lasso	3	0.04	1.1e-05	5.3	5.5	4.1e-08	-0.04	0.01	0.98	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C12orf60	0.10	0.01	blup	56	0.07	1.6e-05	5.7	5.3	9.2e-08	-0.10	0.01	0.88	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	C12orf60	0.05	0.03	lasso	1	0.01	1.2e-02	5.3	5.3	1.0e-07	-0.04	0.02	0.84	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	C12orf60	0.16	0.16	enet	10	0.18	1.3e-17	5.3	6.2	6.3e-10	-0.05	0.01	0.98	TRUE