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chr15:39,530,508-42,393,169

Best TWAS P=2.47e-11 · Best GWAS P=3.08e-08 conditioned to 0.416

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	EXD1	0.04	0.04	lasso	3	0.04	8.1e-06	-5.2	5.2	2.0e-07	-0.94	0.03	0.97	FALSE
2	GTEx	Adipose Visceral Omentum	OIP5-AS1	0.23	0.16	lasso	10	0.11	2.8e-06	-5.3	-6.0	2.8e-09	0.66	0.04	0.95	FALSE
3	GTEx	Artery Aorta	EIF2AK4	0.31	0.08	enet	29	0.17	1.8e-09	-2.9	6.2	6.9e-10	0.05	0.39	0.52	TRUE
4	GTEx	Artery Aorta	OIP5-AS1	0.16	0.21	enet	26	0.23	5.2e-13	-4.7	-5.8	6.4e-09	0.68	0.32	0.67	FALSE
5	GTEx	Artery Coronary	OIP5-AS1	0.12	0.13	lasso	2	0.14	2.3e-05	-5.3	-5.3	9.2e-08	0.60	0.05	0.92	FALSE
6	GTEx	Brain Cerebellar Hemisphere	NUSAP1	0.24	0.31	lasso	6	0.22	2.0e-06	-5.1	-5.4	6.7e-08	0.64	0.09	0.90	FALSE
7	GTEx	Brain Cerebellum	OIP5	0.16	0.09	lasso	4	0.16	1.8e-05	-5.1	-5.3	1.2e-07	0.68	0.09	0.70	FALSE
8	GTEx	Brain Frontal Cortex BA9	NDUFAF1	0.55	0.37	lasso	8	0.40	1.6e-11	-5.2	5.2	1.9e-07	-0.61	0.06	0.94	FALSE
9	GTEx	Cells Transformed fibroblasts	OIP5-AS1	0.28	0.32	lasso	2	0.32	3.5e-24	-5.2	-5.3	1.4e-07	0.61	0.02	0.98	FALSE
10	GTEx	Colon Sigmoid	OIP5-AS1	0.21	0.27	lasso	3	0.25	3.3e-09	-5.2	-5.2	2.3e-07	0.61	0.06	0.94	FALSE
11	GTEx	Colon Transverse	OIP5-AS1	0.13	0.14	lasso	5	0.15	1.8e-07	-5.2	-5.2	2.3e-07	0.59	0.07	0.92	FALSE
12	GTEx	Esophagus Mucosa	NDUFAF1	0.25	0.18	enet	26	0.24	4.3e-16	-3.9	5.2	2.2e-07	-0.54	0.77	0.20	FALSE
13	GTEx	Esophagus Mucosa	CHP1	0.19	0.10	lasso	7	0.09	1.4e-06	-5.3	5.8	5.5e-09	-0.83	0.04	0.96	FALSE
14	GTEx	Lung	OIP5-AS1	0.09	0.08	enet	14	0.12	2.8e-09	-4.9	-5.6	2.5e-08	0.82	0.09	0.91	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	OIP5-AS1	0.17	0.19	enet	17	0.22	4.3e-12	-5.2	-5.3	1.3e-07	0.65	0.06	0.93	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	CHP	0.01	0.01	blup	54	0.01	1.4e-02	-5.0	5.2	2.5e-07	-0.70	0.02	0.78	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC729082	0.02	0.01	blup	44	0.02	2.9e-04	-4.6	5.8	5.3e-09	-0.69	0.03	0.94	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CHP	0.06	0.01	blup	54	0.03	4.7e-04	-5.3	6.7	2.5e-11	-0.80	0.01	0.90	TRUE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NDUFAF1	0.23	0.15	lasso	3	0.13	3.7e-06	-4.9	-5.2	2.5e-07	0.61	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC729082	0.04	0.07	lasso	1	0.06	5.5e-07	-5.2	5.2	2.5e-07	-0.58	0.01	0.98	FALSE