[Hub]/) : Traits : Sitting height : ← →

chr15:50,147,368-52,392,509

Best TWAS P=1.12e-14 · Best GWAS P=2.21e-17 conditioned to 1.92e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TNFAIP8L3 0.12 0.07 blup 462 0.09 1.2e-10 -6.0 -7.7 1.1e-14 -0.61 0.98 0.02 TRUE
2 CommonMind Brain Pre-frontal Cortex TRPM7 0.06 0.03 bslmm 416 0.06 2.8e-08 2.6 5.8 9.0e-09 0.31 0.94 0.01 FALSE
3 GTEx Artery Aorta SPPL2A 0.22 0.03 enet 39 0.11 1.2e-06 3.3 5.3 1.1e-07 0.32 0.69 0.14 FALSE
4 GTEx Artery Coronary GLDN 0.14 0.00 lasso 6 0.00 2.7e-01 6.7 6.7 2.2e-11 0.48 0.09 0.11 FALSE
5 GTEx Lung SPPL2A 0.08 0.08 lasso 4 0.07 6.0e-06 5.4 5.5 3.7e-08 0.30 0.77 0.01 FALSE
6 GTEx Nerve Tibial GLDN 0.10 0.06 lasso 4 0.04 4.7e-04 -6.1 5.9 3.9e-09 0.39 0.55 0.11 FALSE
7 METSIM Adipose TRPM7 0.05 0.00 blup 414 0.03 7.1e-05 6.4 5.7 1.3e-08 0.37 0.04 0.72 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma AP4E1 0.02 0.02 lasso 3 0.01 9.5e-04 5.4 5.9 3.8e-09 0.35 0.01 0.98 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma LOC100132724 0.02 0.01 lasso 3 0.01 1.6e-03 5.9 5.7 9.9e-09 0.40 0.01 0.93 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TNFAIP8L3 0.03 0.00 blup 41 0.01 8.3e-03 6.4 7.6 2.7e-14 0.61 0.01 0.18 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma AP4E1 0.09 0.01 enet 8 0.03 6.5e-04 -6.1 6.7 3.0e-11 0.49 0.01 0.94 FALSE