Hub : Genes

NDUFAF1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1380 0.0380 0.0e+00 0.156 0.192 0.187 0.192 0.185 1.7e-18 6.8e-23 2.9e-22 6.6e-23 4.7e-22
2 GTEx Adipose Visceral Omentum 0.2390 0.0920 2.2e-03 0.016 NA 0.102 NA 0.057 4.5e-02 NA 5.9e-06 NA 6.2e-04
3 GTEx Adrenal Gland 0.1326 0.0783 6.8e-03 0.026 NA -0.008 NA -0.004 4.0e-02 NA 8.6e-01 NA 4.8e-01
4 GTEx Artery Aorta 0.1970 0.0770 1.0e-03 0.009 NA 0.037 NA 0.049 9.6e-02 NA 4.0e-03 NA 1.1e-03
5 GTEx Brain Cerebellar Hemisphere 0.2040 0.0730 6.5e-05 0.227 NA 0.203 NA 0.221 1.6e-06 NA 6.3e-06 NA 2.2e-06
6 GTEx Brain Cerebellum 0.2430 0.0760 1.7e-07 0.261 NA 0.180 NA 0.204 2.4e-08 NA 5.3e-06 NA 1.1e-06
7 GTEx Brain Cortex 0.4020 0.0890 3.8e-12 0.369 NA 0.362 NA 0.359 3.9e-11 NA 7.0e-11 NA 8.3e-11
8 GTEx Brain Frontal Cortex BA9 0.5478 0.1023 2.6e-10 0.369 NA 0.309 NA 0.395 1.1e-10 NA 6.2e-09 NA 1.6e-11
9 GTEx Brain Hypothalamus 0.2400 0.0940 4.2e-04 0.115 NA 0.096 NA 0.130 1.2e-03 NA 3.0e-03 NA 5.9e-04
10 GTEx Brain Nucleus accumbens basal ganglia 0.1170 0.0500 1.2e-03 0.111 NA 0.092 NA 0.105 6.9e-04 NA 2.0e-03 NA 9.7e-04
11 GTEx Cells EBV-transformed lymphocytes 0.3490 0.0810 1.6e-13 0.465 NA 0.512 NA 0.503 5.5e-17 NA 3.1e-19 NA 8.7e-19
12 GTEx Cells Transformed fibroblasts 0.2580 0.0790 1.8e-12 0.151 NA 0.199 NA 0.205 1.9e-11 NA 6.6e-15 NA 2.8e-15
13 GTEx Colon Sigmoid 0.1540 0.0670 2.2e-04 0.056 NA 0.040 NA 0.055 5.0e-03 NA 1.5e-02 NA 5.2e-03
14 GTEx Esophagus Gastroesophageal Junction 0.1890 0.0690 6.1e-07 0.131 NA 0.158 NA 0.162 1.9e-05 NA 2.5e-06 NA 1.8e-06
15 GTEx Esophagus Mucosa 0.2460 0.0610 1.0e-14 0.185 NA 0.240 NA 0.238 2.0e-12 NA 4.3e-16 NA 5.8e-16
16 GTEx Esophagus Muscularis 0.2390 0.0560 1.7e-16 0.226 NA 0.272 NA 0.280 7.8e-14 NA 8.8e-17 NA 2.8e-17
17 GTEx Heart Atrial Appendage 0.3570 0.0900 5.1e-13 0.282 NA 0.335 NA 0.302 4.4e-13 NA 9.5e-16 NA 4.8e-14
18 GTEx Heart Left Ventricle 0.4928 0.0647 0.0e+00 0.618 NA 0.618 NA 0.621 3.5e-41 NA 3.9e-41 NA 2.0e-41
19 GTEx Lung 0.3416 0.0742 1.4e-14 0.183 NA 0.195 NA 0.176 5.7e-14 NA 7.1e-15 NA 1.7e-13
20 GTEx Muscle Skeletal 0.4388 0.0554 0.0e+00 0.563 NA 0.599 NA 0.595 1.7e-66 NA 2.9e-73 NA 2.1e-72
21 GTEx Nerve Tibial 0.3638 0.0680 0.0e+00 0.428 NA 0.414 NA 0.429 9.4e-33 NA 2.2e-31 NA 8.0e-33
22 GTEx Pancreas 0.4130 0.0730 2.2e-16 0.386 NA 0.421 NA 0.416 2.3e-17 NA 2.7e-19 NA 5.4e-19
23 GTEx Prostate 0.3020 0.1230 5.3e-04 0.119 NA 0.099 NA 0.137 6.7e-04 NA 1.9e-03 NA 2.7e-04
24 GTEx Skin Not Sun Exposed Suprapubic 0.1620 0.0850 6.5e-03 0.061 NA 0.033 NA 0.066 2.9e-04 NA 6.1e-03 NA 1.7e-04
25 GTEx Thyroid 0.2470 0.0680 5.7e-14 0.214 NA 0.193 NA 0.220 2.5e-16 NA 9.5e-15 NA 9.3e-17
26 GTEx Whole Blood 0.2520 0.0700 3.8e-08 0.073 NA 0.113 NA 0.117 2.7e-07 NA 1.4e-10 NA 6.4e-11
27 METSIM Adipose 0.0814 0.0281 1.8e-11 0.095 0.087 0.076 0.090 0.089 4.8e-14 5.1e-13 1.6e-11 2.4e-13 2.7e-13
28 TCGA Breast Invasive Carcinoma 0.0435 0.0230 2.8e-06 0.024 0.026 0.032 NA 0.035 9.8e-06 3.4e-06 2.6e-07 NA 8.9e-08
29 TCGA Cervical Squamous Cell Carcinoma 0.1600 0.0790 1.7e-03 0.024 0.048 0.021 NA 0.033 2.4e-02 2.1e-03 3.0e-02 NA 9.8e-03
30 TCGA Head and Neck Squamous Cell Carcinoma 0.0805 0.0535 1.8e-03 0.000 0.018 0.004 NA 0.006 3.5e-01 3.8e-03 9.9e-02 NA 5.6e-02
31 TCGA Kidney Renal Clear Cell Carcinoma 0.1443 0.0661 1.5e-10 0.067 0.094 0.100 NA 0.084 5.5e-08 1.0e-10 2.5e-11 NA 9.9e-10
32 TCGA Brain Lower Grade Glioma 0.0345 0.0204 4.9e-06 0.041 0.037 0.029 NA 0.038 1.6e-05 4.1e-05 2.4e-04 NA 3.2e-05
33 TCGA Lung Adenocarcinoma 0.1441 0.0586 0.0e+00 0.167 0.175 0.174 NA 0.182 4.6e-19 5.9e-20 8.0e-20 NA 9.6e-21
34 TCGA Pancreatic Adenocarcinoma 0.2270 0.1170 7.0e-07 0.149 0.079 0.100 NA 0.132 8.5e-07 3.4e-04 5.7e-05 NA 3.7e-06
35 TCGA Pheochromocytoma and Paraganglioma 0.1770 0.0800 7.7e-08 0.208 0.215 0.208 NA 0.205 9.9e-09 5.4e-09 1.0e-08 NA 1.3e-08
36 TCGA Prostate Adenocarcinoma 0.1333 0.0551 5.6e-17 0.162 0.164 0.169 NA 0.162 1.2e-16 7.7e-17 2.2e-17 NA 1.3e-16
37 TCGA Stomach Adenocarcinoma 0.1060 0.0610 1.2e-03 0.021 0.045 0.021 NA 0.030 1.2e-02 3.4e-04 1.1e-02 NA 2.9e-03
38 TCGA Thyroid Carcinoma 0.3210 0.0940 0.0e+00 0.375 0.383 0.386 NA 0.385 2.3e-38 2.2e-39 1.2e-39 NA 1.4e-39

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38
Bipolar Disorder (2018) 5.1 8.0 13.5 2.8 1.9 2.5 -1.9 2.9 3.4 3.0 2.8 3.2 3.1 3.4 3.5 3.2 3.7 3.1 3.2 3.3 3.1 -2.1 3.2 -3.1 -3.0 -3.0 2.3 -3.4 -3.1 2.9 -2.4 0.9 1.4 -3.1 2.5 -2.9 0.0 -2.8 -2.6 -2.5 -2.8
Bipolar Disorder or Schizophrenia 0.9 2.2 4.0 1.4 0.6 1.5 -1.2 1.5 2.0 1.9 1.5 1.4 1.8 1.8 1.8 1.3 1.1 1.7 1.3 1.9 1.7 -1.3 1.9 -1.8 -1.4 -1.3 0.9 -2.0 -1.9 1.0 -1.4 0.6 1.0 -1.6 1.2 -1.6 0.0 -1.5 -1.4 -1.2 -1.5
Depressed Affect (Nagel 2018) 0.4 0.9 2.0 -0.7 0.6 0.8 0.3 -1.0 -1.1 -0.4 -1.0 -1.1 -1.0 -1.2 -1.0 -0.9 -0.2 -1.4 -1.0 -1.1 -0.9 0.4 -1.4 1.0 1.4 1.4 0.1 1.1 1.2 -0.4 1.2 -0.0 0.2 0.6 -0.9 1.1 1.1 1.1 0.8 1.0 1.1
Depression (Nagel 2018) 0.3 0.4 1.3 0.1 0.9 0.6 0.3 -0.8 -0.6 -0.2 -0.2 -0.3 -0.8 -0.6 -0.2 0.4 0.2 0.1 -0.2 -0.7 -0.6 0.9 -0.7 0.6 0.8 0.7 1.1 0.7 0.6 -0.2 1.1 0.5 0.8 0.5 -0.4 0.8 0.6 0.8 0.5 1.1 0.8
Intelligence (Savage-Jansen 2018) 0.2 0.7 1.7 0.9 0.6 0.4 0.3 -1.2 -0.8 -0.7 -1.2 -1.1 -1.1 -1.1 -1.0 -1.0 -0.6 -0.8 -1.0 -1.2 -0.9 -0.5 -1.1 0.8 1.1 0.5 -0.5 0.9 0.7 -0.4 0.5 -1.0 -1.3 0.3 -0.8 0.7 1.1 0.8 0.5 0.1 0.8
Neuroticism (Nagel 2018) 0.3 0.6 1.8 -0.8 0.3 0.5 0.2 -0.8 -1.0 -0.4 -0.8 -1.1 -0.7 -1.0 -0.9 -1.0 -0.3 -1.1 -0.9 -0.7 -0.6 0.2 -1.2 0.8 1.0 1.4 -0.1 0.8 1.0 -0.8 0.9 -0.1 0.6 0.4 -0.8 0.8 1.1 0.9 0.7 0.8 0.9
Schizophrenia (2018) 0.1 0.3 2.3 -0.4 -0.8 -0.1 -0.3 -0.4 -0.3 -0.0 -0.3 -0.8 -0.1 -0.4 -0.5 -1.0 -1.5 -0.5 -1.0 -0.3 -0.3 -0.0 -0.3 0.2 0.5 0.7 -0.7 0.2 0.0 -1.1 0.2 -0.0 -0.0 0.4 -0.5 0.3 0.0 0.4 0.3 0.4 0.3
Schizophrenia vs Biploar Disorder 2.0 2.7 5.5 -2.0 -0.2 -0.8 0.4 -1.9 -1.8 -1.6 -2.1 -1.5 -1.7 -1.7 -1.8 -1.1 -2.4 -1.5 -2.0 -2.0 -1.8 0.9 -1.8 1.9 1.9 1.8 -0.9 1.6 1.2 -2.3 1.6 -1.1 -1.4 1.9 -1.8 1.8 0.0 1.9 1.5 1.4 1.8
Worry (Nagel 2018) 0.2 0.4 2.6 -0.3 0.3 0.4 0.5 -0.4 -0.7 0.2 -0.3 -1.0 -0.1 -0.6 -0.6 -0.7 -0.8 -0.7 -0.8 -0.1 -0.2 0.2 -0.8 0.4 0.6 1.0 0.2 0.6 0.8 -0.8 0.8 0.5 1.6 0.2 -0.4 0.5 1.0 0.7 0.4 1.1 0.6
Alzheimer’s Disease (in mother) 0.2 0.2 1.1 1.0 1.0 -0.1 -0.6 0.4 0.3 0.2 0.4 0.1 0.4 0.3 0.2 0.2 -0.1 0.4 0.1 0.2 0.4 -0.6 0.3 -0.2 -0.5 -0.5 0.2 -0.4 -0.1 -0.1 -0.3 -0.0 -0.9 -0.7 0.4 -0.4 -0.3 -0.4 -0.6 -0.8 -0.4
Alzheimer’s Disease (in father) 4.4 4.8 11.7 1.5 0.4 3.4 -0.9 2.4 2.5 2.0 2.0 3.2 2.0 2.6 2.9 2.3 2.8 2.3 2.8 2.1 2.2 -1.2 2.4 -2.2 -1.9 -2.5 1.1 -2.3 -2.7 2.5 -2.2 -0.3 1.4 -2.1 2.0 -2.2 -1.8 -2.2 -1.8 -1.7 -2.2
Alzheimer’s Disease (including proxy) 1.6 2.3 4.0 2.0 1.1 1.1 -0.9 1.8 1.6 1.3 1.7 1.8 1.6 1.8 1.8 1.8 1.7 2.0 1.8 1.5 1.6 -0.8 1.7 -1.5 -1.7 -1.6 1.1 -1.7 -1.5 1.4 -1.3 0.1 0.5 -1.8 1.5 -1.6 -1.3 -1.6 -1.6 -1.4 -1.6
Crohns Disease (2017) 0.2 0.4 3.4 -0.2 -0.1 -0.0 -0.4 -0.7 -0.4 -0.5 -0.9 -0.4 -0.6 -0.6 -0.5 -0.5 0.1 -0.7 -0.7 -0.8 -0.7 -0.5 -0.8 0.5 0.7 0.7 -0.3 0.4 -0.3 -0.5 0.5 0.3 -1.8 0.7 -0.8 0.6 0.6 0.7 0.6 0.0 0.7
Irritable Bowel Disease (IBD) 2.1 5.1 12.0 2.7 0.0 2.2 -1.9 2.4 2.7 2.6 2.3 2.2 2.4 2.5 2.5 2.5 2.4 2.2 2.6 2.3 2.3 -2.2 2.5 -2.3 -2.3 -2.6 1.9 -2.7 -3.5 2.3 -1.5 1.6 0.1 -1.7 2.2 -2.1 -2.1 -2.1 -2.1 -1.3 -2.1
Ulcerative Colitis (UC) 7.5 14.0 24.9 4.1 0.1 3.5 -3.0 4.1 4.4 4.2 4.1 3.7 4.1 4.2 4.3 4.0 3.6 3.6 4.4 4.1 4.0 -3.0 4.3 -3.9 -4.1 -4.5 3.0 -4.4 -5.0 4.0 -2.8 1.8 1.3 -3.2 4.0 -3.7 -3.7 -3.7 -3.8 -2.1 -3.7
Major Depression (MDD) 3.0 3.6 9.8 -2.0 1.0 -1.9 1.2 -2.1 -2.2 -1.5 -1.8 -2.1 -1.5 -1.8 -1.7 -0.9 -1.5 -1.0 -1.9 -1.6 -2.1 1.4 -1.9 2.2 1.7 1.9 0.3 1.9 1.0 -2.7 2.9 1.9 0.4 3.0 -2.1 2.3 0.0 2.5 2.2 3.1 2.4
Reaction Time 0.5 0.9 4.2 -2.0 0.1 -1.3 0.1 -0.9 -0.9 -0.5 -0.6 -0.6 -0.5 -0.5 -0.5 -0.0 -1.1 -0.7 -0.9 -0.4 -0.8 0.9 -0.7 0.8 0.4 0.4 0.3 0.4 -0.2 -1.9 1.4 1.5 -0.2 1.6 -0.9 1.0 0.7 1.1 0.9 1.5 1.0
Verbal and Numeric Reasoning (VNR) 0.1 0.2 2.3 1.5 0.2 0.3 0.1 -0.2 -0.0 -0.2 -0.3 0.1 -0.3 -0.3 -0.1 -0.5 0.2 -0.4 -0.2 -0.4 -0.2 -0.5 -0.3 0.2 0.3 -0.3 -0.0 0.3 0.7 0.3 -0.1 -1.0 -0.6 -0.5 0.0 -0.1 0.3 0.0 -0.3 -0.3 0.1
Breast Cancer 0.1 0.3 1.9 1.0 -0.5 -1.1 -0.4 -0.1 -0.3 -0.1 -0.3 -0.8 0.1 -0.3 -0.6 -0.7 -1.1 -0.4 -0.6 -0.1 -0.2 -1.4 -0.1 0.2 -0.0 -0.4 -0.5 -0.5 -1.3 -0.5 0.6 -0.0 0.2 0.3 -0.4 0.1 0.4 0.4 0.1 0.6 0.3
Ovarian Cancer 6.0 7.9 12.9 -3.6 -0.3 -1.8 1.9 -3.1 -3.2 -3.3 -3.3 -2.1 -3.1 -2.9 -2.7 -2.8 -2.8 -2.9 -3.2 -3.3 -3.1 2.7 -3.2 3.0 3.1 3.3 -2.3 3.3 3.3 -3.2 2.2 -1.2 -1.6 2.4 -3.2 2.8 3.0 3.0 2.8 1.7 3.0
Prostate Cancer 0.7 1.0 4.6 0.0 -2.2 0.1 -0.7 1.0 0.9 0.5 1.1 0.3 0.6 0.5 0.3 -0.1 0.3 -0.3 0.8 0.7 1.0 -1.4 0.9 -0.9 -1.2 -1.0 -1.0 -1.1 -1.3 1.0 -1.8 -0.5 -0.3 -1.7 1.2 -1.1 -0.7 -1.4 -0.8 -2.0 -1.2
Age at First Birth 0.2 0.2 2.6 1.0 -0.4 0.9 0.4 0.2 0.3 0.2 0.0 0.5 0.2 0.3 0.5 -0.0 0.8 0.2 0.5 0.3 0.4 0.3 0.3 -0.3 -0.1 -0.5 0.4 -0.2 -0.4 1.6 -0.4 -0.2 0.4 -0.4 0.0 -0.5 0.0 -0.3 -0.2 -0.4 -0.3
Bipolar Disorder (2011) 0.6 0.6 2.9 -0.2 -0.9 -0.4 -1.2 0.6 0.6 -0.2 0.3 0.3 0.3 0.5 0.2 -0.4 0.1 0.1 0.3 0.5 0.6 -0.6 0.5 -0.7 -0.9 -0.4 -1.2 -0.8 -0.9 0.2 -1.7 -1.7 -0.6 -1.4 0.7 -0.6 0.0 -1.0 -0.6 -1.6 -0.9
Body Mass Index (BMI) (2010) 2.6 3.6 6.1 -1.2 0.6 -1.3 1.2 -2.2 -2.1 -1.9 -2.2 -2.2 -2.1 -2.3 -2.2 -1.4 -1.9 -1.3 -2.2 -2.3 -2.1 1.4 -2.2 2.2 2.5 2.2 -0.6 2.4 2.3 -1.9 1.8 -0.5 -1.0 2.3 -2.1 2.1 0.0 2.1 2.0 1.9 2.0
Coronary Artery Disease (CAD) 0.1 0.1 0.8 -0.4 -0.9 0.9 0.4 0.2 0.2 0.1 -0.0 0.2 0.0 -0.2 0.0 -0.5 0.1 -0.4 0.1 -0.1 0.2 -0.1 -0.1 -0.1 0.4 0.3 -0.3 0.5 0.8 0.5 -0.4 -0.4 -0.0 -0.4 0.1 -0.1 0.0 -0.2 0.0 -0.3 -0.2
Crohns Disease (2012) 0.2 0.3 1.5 0.8 1.2 1.2 -0.9 0.0 0.6 0.5 -0.2 0.5 0.3 0.4 0.6 0.6 0.8 0.5 0.2 0.2 0.3 -1.2 0.3 -0.3 0.0 -0.4 0.5 -0.6 -1.1 0.4 -0.2 -0.2 -0.3 -0.1 -0.2 -0.2 0.0 -0.0 -0.3 0.0 -0.1
Mean Putamen Volume 0.5 0.5 3.1 -0.3 -0.6 -0.1 -0.4 -0.7 -0.6 -0.6 -0.9 -1.1 -0.9 -1.1 -0.9 -1.8 -0.5 -1.0 -1.0 -0.9 -0.5 0.2 -0.9 0.8 1.0 0.8 -1.1 0.8 0.4 -0.5 0.2 -0.7 -0.7 0.5 -0.6 0.4 0.0 0.6 0.4 0.4 0.4
Fasting Glucose 0.1 0.1 1.2 0.2 -0.1 -1.1 -0.5 0.3 -0.2 -0.4 0.4 0.1 0.1 0.0 0.1 -0.2 -0.9 -0.1 -0.0 -0.0 0.2 0.3 0.1 -0.1 -0.6 0.0 -0.1 -0.1 0.3 -0.1 -0.0 0.1 -0.4 -0.1 0.4 -0.3 0.0 -0.2 -0.3 -0.1 -0.3
HbA1C 0.1 0.1 0.7 0.1 -0.7 -0.2 0.7 0.2 -0.0 -0.1 0.2 -0.1 0.0 0.2 -0.2 -0.0 0.9 0.3 0.5 0.4 0.1 -0.5 0.3 -0.1 -0.5 -0.3 -0.2 -0.2 -0.5 0.1 0.1 0.7 0.7 0.1 0.1 -0.1 0.0 -0.1 0.1 0.1 -0.1
HDL Cholesterol 1.1 1.9 7.9 2.2 0.5 2.8 -0.3 1.3 1.3 2.1 1.6 1.6 1.4 1.5 1.6 1.6 1.1 1.4 1.7 1.4 1.3 -1.5 1.3 -1.1 -1.0 -1.1 1.3 -1.4 -2.0 1.6 -0.4 1.4 1.1 -0.8 1.2 -0.9 0.0 -1.0 -0.8 -0.5 -0.9
LDL Cholesterol 0.1 0.1 1.0 -0.0 0.8 -0.6 0.2 0.3 0.2 0.4 0.5 0.2 0.4 0.3 0.2 0.5 -0.0 0.3 0.3 0.5 0.3 0.2 0.3 -0.2 -0.4 0.2 0.6 0.1 0.3 -0.2 0.3 1.0 0.6 -0.0 0.3 -0.2 0.0 -0.1 -0.1 0.3 -0.1
Lupus 1.3 2.0 7.5 -1.6 -1.9 -1.1 -0.4 -1.1 -1.4 -1.6 -1.5 -2.2 -1.4 -1.7 -2.0 -2.7 -1.8 -2.4 -1.8 -1.4 -1.0 0.3 -1.5 0.9 1.0 1.0 -2.6 0.9 1.1 -1.1 -0.3 -2.2 -1.2 0.0 -0.9 0.6 0.8 0.6 0.6 -0.4 0.6
Neuroticism (2016) 2.1 3.0 4.6 -1.9 -0.8 -1.7 0.8 -1.8 -2.1 -2.0 -1.8 -2.0 -2.0 -2.1 -2.0 -1.9 -1.3 -2.1 -1.9 -1.9 -1.9 1.5 -2.1 2.1 1.6 1.7 -1.0 1.9 1.6 -1.9 1.5 -0.3 0.2 1.3 -1.6 1.9 1.8 1.8 1.8 1.3 1.8
Primary Biliary Cirrhosis 0.4 0.6 3.6 -0.6 -1.1 -0.7 -0.8 -0.5 -0.5 -0.9 -0.8 -0.6 -0.6 -0.7 -0.7 -1.1 -0.8 -1.5 -0.9 -0.8 -0.5 -0.2 -0.7 0.5 0.3 0.4 -1.4 0.2 0.4 -0.5 -0.2 -1.0 -1.9 0.1 -0.3 0.3 0.0 0.2 0.2 -0.6 0.2
Rheumatoid Arthritis 2.1 2.9 4.8 1.9 -0.0 1.8 -1.9 1.8 2.2 2.2 1.7 1.4 2.0 1.9 1.9 1.4 1.6 1.2 1.7 1.9 2.0 -1.3 1.8 -1.9 -1.7 -1.9 1.3 -2.1 -2.0 2.1 -1.4 0.5 0.3 -2.0 1.9 -1.8 0.0 -1.8 -1.9 -1.6 -1.8
Schizophrenia (2014) 0.1 0.1 1.0 -0.4 0.1 0.1 -0.4 -0.4 0.0 0.1 -0.5 -0.5 -0.0 -0.1 -0.2 -0.5 -1.0 -0.1 -0.8 -0.2 -0.1 0.3 -0.1 0.2 0.5 0.8 -0.3 0.2 0.3 -0.7 0.0 -0.3 -0.1 0.2 -0.5 0.1 0.0 0.4 0.2 0.2 0.3
Triglycerides 2.1 3.5 11.6 -3.1 -0.8 -3.4 0.6 -1.8 -2.1 -2.8 -2.0 -1.9 -2.1 -2.2 -2.0 -2.1 -1.7 -2.3 -2.1 -1.9 -2.0 1.7 -1.9 1.8 1.2 1.9 -2.0 1.8 2.4 -2.0 0.8 -1.6 -1.0 1.4 -1.7 1.5 0.0 1.5 1.6 0.9 1.5
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.2 0.3 0.3 -0.2 -0.6 0.4 0.6 0.4 0.5 0.3 0.6 0.6 0.6 1.1 0.3 0.6 0.4 0.6 0.5 0.4 0.7 -0.6 -0.4 -0.6 0.6 -0.5 -0.2 0.5 -0.4 0.1 0.1 -0.5 0.5 -0.7 0.0 -0.6 -0.7 -0.5 -0.6
Ulcerative Colitis 7.5 10.9 17.7 3.8 0.6 3.4 -3.1 3.4 3.9 4.0 3.4 3.3 3.8 3.8 3.9 3.7 3.3 3.2 3.6 3.6 3.6 -2.9 3.7 -3.5 -3.4 -4.0 3.0 -3.9 -4.2 3.7 -2.4 1.6 0.9 -3.4 3.4 -3.2 0.0 -3.2 -3.4 -2.3 -3.1
Blood Eosinophil Count 3.2 25.0 40.1 -4.4 -1.1 -4.5 3.8 -5.5 -5.9 -5.7 -5.2 -5.1 -5.8 -5.7 -5.5 -5.2 -6.3 -4.4 -5.3 -5.6 -5.9 5.6 -5.6 5.5 5.4 5.3 -3.6 5.7 5.2 -4.3 4.3 -0.5 -2.0 4.4 -5.3 5.3 5.4 5.3 5.4 3.0 5.4
Blood Platelet Count 0.2 2.6 4.8 -2.1 -0.6 0.2 0.7 -2.0 -1.7 -0.9 -1.7 -1.7 -1.8 -2.0 -1.8 -1.7 -0.7 -2.2 -1.9 -1.7 -1.7 0.3 -2.2 1.8 2.2 1.7 -0.7 1.7 1.2 -1.8 1.6 0.4 -0.5 1.5 -1.5 1.9 2.0 1.9 1.7 1.4 1.9
Blood Red Count 0.6 5.7 25.5 0.0 4.1 -0.3 -0.4 2.5 2.6 1.4 2.8 3.3 2.1 3.1 2.5 5.0 1.9 4.4 3.0 2.5 1.9 1.1 3.3 -2.2 -2.6 -2.2 2.7 -1.9 -0.6 -0.1 -1.5 0.9 0.8 -0.6 2.2 -2.1 -3.4 -2.1 -2.0 -0.3 -2.3
Blood White Count 1.2 8.8 17.4 0.7 0.2 1.6 -3.6 3.1 3.4 3.4 3.3 2.6 3.5 3.4 2.8 3.5 2.5 1.9 2.6 3.3 3.3 -3.7 3.4 -3.4 -3.6 -4.1 1.6 -4.0 -4.2 1.1 -2.6 0.0 0.4 -2.3 3.4 -3.2 -3.7 -3.1 -3.6 -1.5 -3.3
Heel T-Score 0.4 3.4 8.1 -0.6 1.9 1.2 1.7 -2.5 -1.6 -1.6 -2.5 -0.6 -2.1 -1.6 -1.1 -0.3 -0.2 -0.1 -1.3 -2.5 -2.2 2.3 -2.2 2.2 2.8 1.9 0.5 2.6 2.3 -0.2 2.0 -0.1 -1.0 1.8 -2.2 2.4 2.5 2.3 2.2 1.3 2.4
BMI 2.9 17.0 27.9 -2.6 2.3 -3.0 3.3 -5.0 -4.5 -4.5 -4.7 -2.9 -4.9 -4.3 -3.7 -2.7 -3.0 -1.9 -4.3 -5.0 -4.9 4.7 -4.5 4.8 5.2 5.3 -1.1 5.1 4.9 -4.0 4.3 0.1 -2.2 4.4 -4.6 4.8 4.6 4.8 4.6 3.4 4.8
Height 4.3 82.1 136.9 9.4 1.4 2.0 -3.4 11.2 10.2 7.8 11.4 10.6 9.7 10.3 9.6 9.4 6.7 9.8 11.0 10.6 10.0 -3.6 11.7 -10.2 -11.4 -10.0 4.3 -9.4 -7.0 9.3 -9.1 1.3 4.3 -8.7 10.7 -10.3 -11.4 -10.8 -9.4 -7.1 -10.7
Waist Hip Ratio (WHR) 0.5 2.2 14.2 -1.6 -2.7 -3.8 -2.1 1.4 0.7 -0.2 1.3 0.3 1.1 1.0 0.4 0.4 -0.8 0.2 0.4 1.3 1.0 -0.9 1.6 -1.3 -2.5 -2.2 -1.3 -2.0 -2.6 -1.2 -1.2 -0.4 0.2 -0.6 1.2 -1.4 -2.1 -1.4 -1.2 -0.7 -1.5
Systolic Blood Pressure 2.6 12.9 52.7 -5.0 -5.0 -3.8 -1.1 -2.5 -3.4 -5.0 -4.0 -3.6 -3.8 -3.9 -3.9 -7.1 -2.4 -5.5 -3.8 -3.7 -2.7 -0.3 -3.7 2.5 1.9 2.8 -7.3 2.3 2.5 -3.0 -1.1 -5.7 -4.5 -0.3 -2.5 1.4 2.3 1.3 1.9 -2.3 1.5
Smoking Status 0.2 0.6 3.3 -0.7 -1.8 -1.6 -1.1 0.3 0.0 -0.4 0.3 -0.5 0.1 0.1 -0.6 -0.1 -1.6 -0.4 -0.3 0.1 0.2 -0.3 0.2 -0.2 -0.6 -0.7 -1.4 -0.5 -0.9 -0.6 -0.8 -0.6 -1.4 -0.3 0.4 -0.4 -0.9 -0.5 -0.3 -0.9 -0.5
Allergy or Eczema 13.0 34.2 73.5 -5.2 -4.1 -3.7 4.5 -6.0 -7.1 -6.7 -6.3 -6.2 -7.1 -7.2 -6.9 -8.6 -6.1 -6.9 -6.4 -6.6 -6.1 4.4 -6.8 6.1 6.2 6.9 -6.8 6.6 6.1 -4.7 3.5 -2.6 -2.6 3.8 -5.9 5.6 5.9 5.3 6.1 1.9 5.5
Cardiovascular Disease 5.1 17.0 51.6 -5.2 -5.1 -4.5 -0.7 -3.9 -4.6 -5.0 -4.7 -4.8 -4.7 -4.9 -4.8 -7.2 -3.9 -6.3 -5.0 -4.5 -3.8 1.2 -4.6 3.7 3.2 3.8 -6.2 3.1 2.7 -3.7 1.1 -3.9 -3.7 1.5 -3.7 3.0 3.8 2.9 3.1 -0.1 3.1
Hypothyroidism (self reported) 1.2 2.8 8.9 -2.4 -1.1 -3.0 0.8 -1.6 -2.1 -2.4 -1.5 -1.6 -1.9 -1.9 -1.8 -2.0 -1.8 -1.8 -1.9 -1.8 -1.8 1.5 -1.8 1.6 1.2 1.5 -1.9 1.6 1.8 -1.9 0.7 -0.7 -1.8 1.3 -1.5 1.4 1.2 1.3 1.6 0.4 1.4
Respiratory disease 6.5 14.4 24.4 -3.5 -3.1 -3.1 2.0 -4.1 -4.5 -4.2 -4.3 -4.9 -4.4 -4.8 -4.8 -4.8 -4.2 -4.5 -4.4 -4.3 -4.0 2.4 -4.6 4.0 4.0 3.8 -3.3 4.0 2.8 -3.3 2.8 -1.2 -1.6 2.9 -4.0 3.9 4.1 3.7 4.0 1.8 3.9
Type 2 Diabetes (T2D) (2018) 2.8 5.2 14.1 -3.1 -1.1 -3.7 -0.2 -2.3 -2.8 -2.8 -2.5 -2.7 -2.1 -2.3 -2.5 -2.3 -2.8 -2.5 -2.6 -2.2 -2.5 1.4 -2.3 2.3 1.4 2.4 -1.8 1.6 0.7 -3.8 2.3 -0.3 -1.2 2.4 -2.4 2.2 1.8 2.4 2.0 1.8 2.3
Lung FEV1/FVC ratio 3.0 15.4 87.0 -4.8 0.1 -9.3 2.8 -3.6 -4.2 -5.5 -3.0 -2.7 -3.7 -3.5 -3.6 -2.0 -4.5 -1.4 -4.0 -3.6 -4.3 6.1 -2.9 4.0 2.3 3.6 -1.9 3.9 5.0 -6.4 3.5 0.6 -1.2 4.1 -3.4 3.7 2.7 3.7 3.6 3.2 3.6
Lung FVC 0.7 3.3 13.3 -0.9 -0.8 2.1 1.0 -1.8 -1.6 -1.5 -2.6 -1.8 -2.1 -2.2 -1.8 -3.6 -0.0 -2.1 -1.9 -2.2 -1.4 0.5 -2.3 1.6 2.7 2.4 -2.5 2.1 2.4 0.1 -0.2 -2.6 -1.1 0.0 -1.8 1.2 2.5 1.2 1.5 -0.6 1.4
Neuroticism 0.3 0.6 1.6 -0.2 0.6 1.0 0.5 -0.8 -0.9 -0.3 -0.7 -1.0 -0.9 -1.1 -0.9 -0.7 -0.6 -0.8 -0.9 -0.9 -0.6 0.4 -1.1 1.0 1.3 0.9 0.1 0.9 1.0 -0.6 0.9 -0.0 0.4 0.2 -0.6 0.9 1.1 0.9 0.7 0.6 0.9
Chronotype (morning person) 0.3 0.7 3.9 0.7 0.7 2.0 -0.8 0.7 1.0 0.9 0.8 0.9 0.8 0.9 0.8 0.9 1.3 0.9 1.0 0.5 0.8 -1.5 0.7 -0.6 -0.5 -0.2 0.1 -0.7 -0.7 0.2 -1.2 -0.7 0.1 -0.9 0.9 -0.7 -0.7 -0.9 -0.7 -0.6 -0.8
Hair Pigment 0.2 4.4 9.2 2.8 0.2 1.9 -1.7 2.2 2.3 2.4 2.6 2.0 2.4 2.4 2.2 3.0 1.1 2.8 2.5 2.3 2.2 -1.4 2.5 -1.9 -2.3 -2.1 2.1 -2.3 -2.8 1.5 -1.3 1.8 0.1 -1.6 2.4 -1.9 -2.1 -2.0 -2.0 -1.3 -2.0
Tanning 0.0 0.3 2.3 -0.1 1.0 1.5 -0.1 0.2 0.5 0.7 0.2 0.7 0.6 0.7 0.9 0.8 1.1 0.4 0.3 0.4 0.5 -0.1 0.4 -0.5 0.0 -0.4 0.9 0.0 0.1 0.5 -0.1 -0.1 0.9 -0.3 -0.2 -0.4 -0.3 -0.2 -0.4 0.4 -0.3
Hand grip strength (left) 1.4 3.6 8.3 1.3 0.6 1.4 -1.1 2.1 2.5 1.2 2.1 2.2 1.7 2.0 1.8 2.0 1.4 2.0 2.3 1.7 2.1 -0.5 2.3 -2.0 -2.0 -1.5 0.2 -1.4 -0.2 2.1 -2.9 -1.2 -0.4 -2.5 2.4 -2.2 -2.2 -2.5 -2.1 -2.6 -2.4
Number of treatments/medications taken 4.6 8.3 19.0 -3.5 -3.0 -4.3 -0.6 -2.7 -3.4 -3.7 -3.2 -4.0 -2.8 -3.4 -3.7 -4.4 -3.0 -4.2 -3.6 -3.0 -2.9 -0.1 -3.2 2.6 1.7 2.8 -3.7 2.0 0.7 -3.5 1.4 -2.1 -2.1 1.7 -2.8 2.3 2.6 2.3 2.4 0.6 2.4
Average weekly spirits intake 0.3 0.4 2.6 0.1 -0.2 -0.0 -1.6 0.4 0.8 0.6 0.6 0.3 0.6 0.8 0.5 1.3 -0.3 0.5 0.3 0.4 0.5 -0.3 0.7 -0.5 -0.5 -0.6 0.7 -0.9 -1.3 -0.3 -0.3 0.3 -0.9 -0.3 0.6 -0.4 -0.5 -0.4 -0.7 -0.4 -0.4
Sensitivity / hurt feelings 1.2 2.0 4.4 -1.5 -0.3 -1.2 -0.2 -1.5 -1.6 -1.4 -1.4 -1.9 -1.4 -1.7 -1.7 -2.0 -1.2 -1.4 -1.7 -1.6 -1.4 0.5 -1.8 1.4 1.4 2.1 -1.3 1.4 1.2 -2.1 0.9 -0.8 -0.1 0.7 -1.3 1.4 1.7 1.4 1.2 1.0 1.4
Frequency of depressed mood in last 2 weeks 0.7 1.0 2.4 -0.8 -0.1 -1.0 0.4 -1.2 -1.2 -1.1 -0.7 -1.2 -1.4 -1.3 -1.2 -0.5 -1.3 -0.7 -1.0 -1.1 -1.1 1.5 -1.1 1.2 1.0 1.1 -0.2 1.0 0.8 -1.4 1.1 0.2 0.2 0.7 -0.8 1.2 1.0 1.1 1.0 1.0 1.1
Hearing difficulty/problems: Yes 0.8 1.2 5.6 2.3 0.7 2.4 -1.2 1.0 1.0 1.5 0.9 0.5 1.3 0.8 0.9 1.1 1.5 1.0 1.1 0.7 1.0 -1.2 0.7 -0.9 -0.4 -0.8 1.8 -0.8 -0.5 1.7 -0.3 0.1 0.4 -1.2 1.0 -0.8 -0.6 -0.8 -1.2 -0.6 -0.8
Relative age of first facial hair 0.6 1.2 3.1 0.9 0.4 0.4 -0.2 1.2 1.1 0.5 1.1 1.4 0.9 1.0 1.1 0.8 0.8 1.1 1.3 1.0 1.2 0.2 1.2 -1.2 -1.3 -0.6 0.2 -0.7 0.4 1.7 -1.8 -0.6 -0.4 -1.3 1.4 -1.3 -1.6 -1.5 -1.1 -1.6 -1.5
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 2.6 0.3 -0.8 0.3 -1.4 0.9 0.7 0.9 0.8 0.1 0.9 0.7 0.4 0.6 0.3 0.4 0.6 0.8 0.8 -1.0 0.7 -0.9 -0.9 -1.2 0.4 -1.2 -1.6 0.2 -0.5 0.1 0.4 -0.7 0.9 -0.8 -0.8 -0.8 -0.9 -0.5 -0.8
Ever used hormone-replacement therapy (HRT) 4.7 6.0 9.0 -2.9 -0.9 -2.4 0.6 -2.9 -2.8 -2.8 -3.0 -3.0 -2.7 -2.8 -2.8 -2.5 -2.2 -3.0 -2.9 -2.9 -2.8 1.1 -2.9 2.7 2.4 2.3 -1.6 2.4 2.0 -2.6 2.0 -1.4 -0.9 2.2 -2.7 2.5 2.6 2.6 2.3 1.8 2.6
Ever had hysterectomy (womb removed) 0.3 0.4 2.3 -0.8 -0.9 -0.7 -1.5 -0.4 -0.4 -0.3 -0.4 -1.0 -0.4 -0.4 -0.6 -0.7 -0.7 -1.4 -0.6 -0.4 -0.1 -0.8 -0.5 0.1 -0.2 0.5 -0.6 -0.1 -0.3 -0.7 -0.2 -1.0 -0.4 -0.4 0.0 0.1 0.2 0.1 -0.2 -0.2 0.1
Systolic blood pressure, automated reading 3.5 10.1 26.9 -4.2 -2.6 -2.9 1.0 -3.0 -3.4 -4.8 -4.4 -2.7 -3.7 -3.4 -3.3 -5.2 -1.8 -3.9 -3.5 -3.8 -3.2 1.0 -3.6 3.1 2.7 3.2 -5.0 2.9 3.1 -2.8 0.3 -4.3 -2.9 1.2 -3.3 2.2 2.9 2.2 2.7 -0.5 2.3
Eye problems/disorders: Diabetes related eye disease 0.7 0.7 3.3 -0.7 -1.8 -1.8 -1.1 0.3 -0.2 -0.8 -0.1 -0.9 -0.2 -0.4 -0.8 -1.2 -0.5 -1.5 -0.3 -0.0 0.2 -0.8 -0.0 -0.2 -0.7 -0.0 -1.7 -0.3 -0.1 -0.3 -0.9 -1.2 -1.5 -1.0 0.3 -0.6 -0.4 -0.6 -0.5 -1.6 -0.5
Angina 3.8 5.0 8.0 -1.8 0.2 -1.2 0.9 -2.6 -2.7 -2.5 -2.8 -2.0 -2.5 -2.4 -2.2 -2.7 -2.0 -2.7 -2.6 -2.6 -2.5 2.2 -2.7 2.4 2.5 2.6 -1.9 2.6 2.4 -1.6 2.1 -1.2 -0.8 1.7 -2.6 2.3 2.6 2.4 2.2 1.3 2.5
Medication for hormone replacement therapy 0.4 0.4 4.8 0.5 -0.5 0.3 1.5 0.1 -0.2 0.3 0.2 0.6 0.1 -0.0 0.3 -0.1 -0.1 0.2 0.1 0.1 -0.0 1.6 -0.1 0.3 0.4 0.3 0.7 0.5 1.0 0.6 0.6 0.7 2.2 0.0 -0.2 0.3 0.6 0.3 0.5 0.7 0.3
Vitamin and mineral supplements 2.1 2.8 7.3 -1.3 1.4 0.7 2.0 -1.9 -1.6 -0.9 -1.6 -1.5 -1.8 -1.7 -1.4 -1.1 -0.9 -0.9 -1.5 -1.8 -1.7 1.5 -1.8 2.0 2.5 2.1 0.2 2.2 2.7 -1.3 1.9 0.3 0.4 1.8 -1.7 1.8 1.9 2.1 1.7 2.1 2.0
Supplements: Zinc 0.5 0.6 2.9 -0.6 -1.1 -1.7 -1.7 0.2 0.3 -0.4 0.1 0.1 0.2 0.2 0.1 -0.4 -0.8 -0.5 -0.4 0.2 0.2 -0.6 0.2 -0.4 -0.8 -0.3 -1.3 -0.7 -0.9 -0.6 -1.2 -0.9 -1.7 -0.5 0.4 -0.5 -0.6 -0.7 -0.6 -1.1 -0.6
Medication: Co-codamol 1.6 1.8 4.6 -1.7 -1.0 -1.0 -0.5 -1.2 -1.5 -1.5 -1.5 -1.8 -1.5 -1.5 -1.8 -1.8 -1.7 -2.1 -1.8 -1.5 -1.3 0.1 -1.3 1.3 1.1 1.1 -2.0 0.9 1.0 -1.7 0.7 -1.3 -2.0 0.7 -1.2 1.0 0.7 0.9 0.8 -0.2 1.0
Medication: Metformin 3.5 5.0 11.0 -3.3 -1.6 -3.1 -1.3 -2.2 -2.4 -2.9 -2.6 -3.0 -2.2 -2.4 -2.7 -2.5 -2.9 -2.9 -2.8 -2.5 -2.2 0.3 -2.2 2.1 1.5 2.1 -2.7 1.5 0.7 -3.2 1.0 -2.2 -2.6 1.4 -2.2 1.7 1.6 1.8 1.5 0.4 1.8
Diabetes (father) 0.7 0.9 4.6 -1.2 0.1 -2.1 -0.2 -0.9 -0.8 -1.6 -1.1 -0.8 -0.9 -0.8 -0.7 -0.4 -1.0 -0.5 -1.0 -0.8 -1.1 1.5 -0.7 0.8 0.4 0.6 -0.3 0.8 1.1 -0.8 0.5 -0.5 -1.7 0.9 -1.1 0.6 0.7 0.7 0.7 -0.0 0.7
Diabetes (mother) 0.2 0.3 3.9 -0.7 -1.0 -2.0 0.5 0.2 -0.2 -0.2 0.4 -0.1 0.2 -0.1 -0.1 -0.1 -0.4 0.1 -0.0 0.4 -0.0 1.2 0.1 -0.0 -0.3 -0.1 -0.2 -0.1 -0.1 -0.7 0.2 1.0 1.2 0.2 0.0 0.1 0.0 0.0 0.3 0.7 0.0
Severe depression (siblings) 1.3 1.5 4.5 1.5 0.2 2.1 -0.2 1.3 1.3 1.7 1.7 1.4 1.1 1.3 1.4 1.7 1.2 1.7 1.6 1.3 1.2 -0.2 1.2 -1.2 -0.6 -0.6 1.7 -0.9 -0.9 1.4 -0.6 1.3 1.5 -0.7 1.3 -0.9 -1.1 -1.0 -0.8 -0.1 -1.0
Pack years adult smoking proportion 2.6 3.9 9.2 -2.6 0.1 -2.3 2.1 -2.1 -2.0 -2.5 -1.8 -1.6 -2.3 -2.0 -1.9 -1.4 -2.0 -1.1 -1.9 -2.2 -2.2 2.9 -2.0 2.2 2.0 2.3 -1.3 2.5 3.0 -1.8 1.1 -0.7 -0.1 2.0 -1.8 1.9 1.6 1.9 2.1 1.8 1.9
Impedance of leg (right) 0.8 3.7 13.8 -3.7 -2.2 -3.0 0.5 -1.9 -2.3 -2.1 -1.8 -2.1 -1.8 -2.0 -2.0 -2.6 -2.2 -3.4 -2.2 -1.5 -1.8 0.9 -2.1 1.6 0.9 1.3 -2.1 1.4 0.8 -2.5 1.6 -0.2 -0.3 1.5 -1.9 1.7 1.8 1.7 1.7 1.1 1.7
Leg fat-free mass (left) 0.6 3.2 13.4 2.5 2.4 1.0 0.7 1.9 2.0 1.1 2.2 3.1 1.3 2.0 2.1 2.7 1.4 3.7 2.3 1.4 1.5 0.9 2.3 -1.5 -1.3 -0.8 1.2 -0.8 0.4 1.7 -1.8 0.2 0.7 -1.5 2.1 -1.5 -2.1 -1.9 -1.3 -1.3 -1.8
Trunk fat percentage 4.4 17.5 25.2 -4.2 0.5 -3.4 3.0 -4.8 -4.8 -5.0 -4.8 -3.1 -4.9 -4.4 -3.9 -3.6 -3.9 -3.1 -4.6 -5.0 -5.0 4.6 -4.6 4.8 4.8 5.0 -2.5 4.9 4.5 -4.4 3.8 -0.8 -2.2 4.1 -4.7 4.6 4.4 4.6 4.6 2.8 4.6
Hand grip strength (right) 2.6 7.0 11.4 2.4 0.5 0.7 -2.2 3.2 3.2 2.1 3.3 2.6 2.8 2.8 2.6 2.7 2.1 2.7 3.1 2.7 3.0 -1.4 3.2 -2.9 -3.1 -2.7 0.8 -2.6 -1.7 2.4 -3.4 -0.6 0.2 -3.0 3.4 -3.1 -3.3 -3.3 -3.0 -2.7 -3.3
Townsend deprivation index at recruitment 3.5 4.9 9.9 -2.5 -2.0 -2.1 0.1 -2.3 -2.4 -2.2 -2.2 -3.1 -2.3 -2.7 -2.9 -2.9 -3.1 -2.3 -2.9 -2.5 -2.1 1.3 -2.5 2.3 2.3 2.3 -2.5 1.9 1.1 -2.8 1.3 -0.6 -1.7 1.8 -1.9 2.2 2.0 2.0 2.1 1.0 2.1
Current tobacco smoking 0.4 0.7 4.0 -0.4 -1.8 -2.0 -1.3 0.5 0.2 -0.2 0.6 -0.8 0.4 0.1 -0.5 -0.6 -1.4 -0.5 -0.3 0.3 0.5 -0.3 0.4 -0.4 -0.9 -0.7 -1.4 -0.6 -0.6 -0.2 -1.1 -0.9 -0.0 -0.9 0.7 -0.8 -0.7 -0.7 -0.6 -0.8 -0.8
Average weekly fortified wine intake 0.3 0.4 1.1 -0.5 -1.1 -0.0 0.6 -0.6 -0.5 -0.3 -0.2 -0.5 -0.5 -0.7 -0.6 -0.6 -0.8 -0.8 -0.5 -0.6 -0.6 -0.4 -0.6 0.8 0.6 0.3 -0.6 0.5 -0.7 -0.7 0.3 0.6 -0.1 0.4 -0.4 0.9 0.8 0.6 0.9 0.5 0.7
Maternal smoking around birth 0.4 0.5 3.3 0.6 -0.1 -0.1 0.1 0.5 0.5 1.0 0.9 0.1 0.5 0.5 0.6 0.9 0.2 0.8 0.7 0.9 0.6 -0.1 0.6 -0.3 -0.5 -0.4 1.4 -0.5 -1.1 0.4 0.5 1.8 1.8 0.2 0.5 -0.2 -0.3 -0.1 -0.2 0.9 -0.2
Fed-up feelings 1.9 3.5 5.8 -1.9 -0.1 -0.9 1.4 -2.0 -2.2 -1.6 -1.8 -2.1 -2.1 -2.3 -2.0 -1.7 -1.3 -1.8 -1.9 -2.0 -1.9 1.6 -2.4 2.2 2.2 2.4 -0.5 2.2 1.9 -1.8 2.1 0.3 0.8 1.5 -1.9 2.1 2.3 2.2 2.1 1.8 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.2 1.1 -0.0 0.9 -0.5 -0.0 -0.6 -0.3 -0.3 -0.1 -0.3 -0.5 -0.5 -0.2 0.5 -0.0 0.2 -0.1 -0.5 -0.5 0.8 -0.4 0.5 0.5 0.3 1.0 0.5 0.5 -0.4 0.8 0.3 0.6 0.4 -0.2 0.7 0.3 0.6 0.3 1.1 0.6
Relative age voice broke 0.5 0.8 2.9 0.3 -0.9 -0.8 -1.0 0.9 0.7 -0.0 0.6 -0.2 0.5 0.3 -0.2 -0.3 -0.8 0.4 0.3 0.5 0.8 -0.6 0.9 -1.0 -1.0 -0.9 -1.2 -0.9 -0.6 0.6 -1.6 -1.6 -1.0 -0.9 1.1 -1.2 -1.7 -1.2 -1.1 -1.4 -1.3
Taking other prescription medications 4.1 6.3 13.5 -2.6 -2.8 -2.1 -0.0 -2.6 -3.0 -3.2 -2.9 -3.3 -2.8 -3.0 -3.2 -3.7 -2.3 -3.5 -2.9 -3.1 -2.7 -0.0 -3.0 2.6 2.1 2.4 -3.4 2.0 0.8 -2.5 0.9 -2.4 -1.6 1.2 -2.4 2.2 2.5 2.0 2.3 0.4 2.2
Age when periods started (menarche) 3.8 9.2 18.2 0.6 -1.9 0.7 -2.1 3.8 3.5 2.1 4.0 3.1 2.9 3.2 2.5 2.8 1.1 2.5 3.4 3.3 3.4 -1.8 4.0 -3.3 -4.0 -3.3 -0.5 -3.4 -3.1 1.7 -4.3 -0.6 0.4 -3.3 3.9 -3.5 -4.3 -4.1 -3.0 -3.3 -4.0
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.0 -0.5 -0.1 -0.9 -0.4 0.6 0.6 0.1 0.7 0.3 0.6 0.5 0.4 0.8 -0.2 0.7 0.5 0.6 0.5 -0.0 0.8 -0.5 -1.0 -0.7 0.0 -0.7 -0.7 -0.5 -0.7 0.1 0.1 -0.3 0.6 -0.6 -0.8 -0.6 -0.5 -0.3 -0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 2.7 -0.7 0.8 0.4 1.4 -1.2 -0.8 -0.5 -0.9 -0.5 -1.2 -1.0 -0.8 -0.1 -0.2 0.0 -0.7 -1.0 -1.1 1.1 -1.1 1.1 1.6 1.3 0.3 1.5 1.6 -0.6 1.0 0.5 0.0 1.0 -1.0 1.3 1.3 1.2 1.2 1.1 1.2
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 2.0 -1.4 -0.6 0.2 0.4 -0.4 -0.5 -0.4 -0.4 -0.5 -0.7 -0.6 -0.5 -0.3 0.5 -0.5 -0.3 -0.4 -0.5 -0.2 -0.6 0.5 0.5 1.2 -0.3 0.6 0.5 -1.1 0.2 0.1 0.1 0.3 -0.3 0.6 0.4 0.4 0.6 0.2 0.4
Qualifications: CSEs or equivalent 1.4 1.8 3.5 1.0 -1.5 -0.6 -1.3 1.9 1.3 1.7 1.9 0.1 1.7 1.0 0.7 0.1 0.3 0.6 1.3 1.8 1.7 -1.5 1.5 -1.7 -1.7 -1.6 0.4 -1.8 -1.8 1.2 -0.8 1.0 1.4 -1.3 1.5 -1.5 -1.5 -1.4 -1.4 -0.7 -1.5
Serious illness, injury or assault to yourself 0.4 0.5 2.5 -0.6 -0.2 -0.9 0.7 -0.3 -0.6 -0.4 -0.0 -0.2 -0.3 -0.3 -0.1 0.4 -0.7 0.5 -0.0 0.1 -0.5 1.0 -0.1 0.4 -0.1 0.5 0.6 0.3 -0.8 -1.0 1.2 1.5 1.6 1.0 -0.5 0.6 0.4 0.7 0.9 1.2 0.6
High blood pressure 4.3 11.9 37.6 -4.5 -4.5 -3.5 -1.0 -3.0 -3.8 -4.2 -3.8 -4.3 -3.8 -4.0 -4.2 -6.1 -3.5 -5.2 -4.2 -3.7 -3.0 0.4 -3.7 3.0 2.5 3.5 -5.7 2.4 2.2 -3.4 0.4 -4.3 -3.0 0.7 -3.0 2.1 3.0 2.1 2.3 -0.7 2.2
Hayfever, allergic rhinitis or eczema 7.5 16.3 44.2 -3.0 -4.0 -3.3 2.7 -3.9 -4.9 -4.8 -4.2 -4.5 -5.0 -5.1 -5.1 -6.7 -4.7 -5.4 -4.6 -4.4 -4.0 2.7 -4.6 3.8 3.9 4.4 -5.5 4.2 4.1 -3.0 2.0 -2.4 -2.3 2.1 -3.7 3.4 3.6 3.2 3.8 0.6 3.4
Multivitamins +/- minerals 0.5 0.6 2.6 0.6 -0.4 -1.5 -0.4 0.8 0.6 0.3 0.7 0.5 1.0 0.9 0.6 1.1 -0.4 0.7 0.5 1.0 0.6 0.1 1.0 -0.8 -1.4 -1.1 0.3 -1.1 -1.6 0.1 -0.3 0.9 0.3 -0.1 0.6 -0.6 -0.8 -0.6 -0.4 -0.2 -0.6
Stomach or abdominal pain in last month 0.3 0.4 1.8 -0.6 0.3 -0.9 0.2 -0.6 -0.7 -0.3 -0.4 -1.0 -0.4 -0.6 -0.5 -0.3 0.1 -0.3 -0.4 -0.3 -0.5 0.6 -0.6 0.5 0.3 1.2 0.4 0.7 0.8 -0.7 0.8 0.7 0.9 0.9 -0.4 0.8 0.5 0.7 0.6 1.4 0.7
Supplements: Glucosamine 1.2 1.5 3.0 0.6 0.2 1.1 -0.1 1.5 1.4 1.6 1.5 1.5 1.5 1.5 1.4 1.3 0.8 1.3 1.4 1.7 1.6 -0.6 1.5 -1.5 -1.4 -1.0 0.8 -1.3 -1.0 0.9 -1.0 0.9 1.1 -0.9 1.5 -1.2 -1.5 -1.4 -1.2 -0.6 -1.4
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.5 -0.6 0.2 0.5 -0.4 -0.7 -0.5 -0.8 -1.0 -0.3 -0.8 -0.4 -0.3 -0.1 0.4 -0.4 -0.4 -0.7 -0.6 0.1 -0.6 0.5 0.5 0.7 -0.1 0.4 0.2 -0.3 0.0 -1.2 -0.2 0.1 -0.8 0.4 0.8 0.5 0.5 0.0 0.5
Medication: Atenolol 3.1 3.9 6.1 -1.9 -0.9 -1.2 -0.0 -2.2 -2.3 -2.3 -2.3 -2.4 -2.4 -2.3 -2.4 -2.5 -2.3 -2.3 -2.4 -2.4 -2.2 0.4 -2.3 2.1 2.0 2.4 -2.4 1.7 1.1 -2.3 1.2 -1.4 -1.9 1.4 -2.1 1.8 1.9 1.9 1.8 0.6 1.9
Medication: Levothyroxine sodium 2.8 4.8 11.3 -2.7 -1.2 -3.4 0.5 -2.3 -2.7 -2.8 -2.3 -2.7 -2.4 -2.6 -2.7 -2.4 -2.1 -2.7 -2.5 -2.4 -2.4 1.2 -2.5 2.4 1.7 1.9 -1.8 1.8 1.5 -2.5 1.7 -0.5 -1.7 2.1 -2.2 2.2 1.8 2.1 2.1 1.3 2.1
Sitting height 2.2 15.7 27.1 4.8 2.2 2.0 -0.2 4.8 4.4 3.9 5.2 5.1 4.3 4.5 4.3 5.0 3.4 5.2 5.0 4.5 4.2 -1.3 5.1 -4.0 -4.4 -3.8 3.1 -3.6 -2.1 3.7 -3.1 1.9 2.1 -3.1 4.7 -4.0 -5.2 -4.3 -3.8 -2.3 -4.3
Chronic bronchitis/emphysema (father) 0.6 0.7 4.1 -0.0 0.6 1.9 -1.3 0.5 0.7 0.7 0.5 0.6 0.5 0.8 0.8 1.0 1.1 0.5 0.8 0.5 0.7 -1.9 0.7 -0.6 -0.6 -0.7 0.4 -1.1 -2.0 0.4 -0.7 -0.1 -0.9 -0.6 0.5 -0.7 -0.4 -0.6 -0.6 -0.8 -0.6
High blood pressure (mother) 0.5 0.7 6.4 -1.6 -2.5 -1.3 0.2 -0.1 -0.8 -0.9 -0.2 -0.6 -0.7 -0.7 -0.8 -1.7 -1.2 -1.2 -0.7 -0.3 -0.4 0.6 -0.4 0.3 0.1 0.5 -2.0 0.2 0.4 -1.0 -0.3 -0.9 0.5 -0.1 -0.3 0.1 0.2 0.0 0.4 -0.3 0.1
Body mass index (BMI) 2.7 11.6 19.7 -2.7 1.9 -2.0 2.8 -4.0 -3.8 -3.9 -4.0 -2.2 -4.0 -3.5 -3.0 -2.4 -2.4 -1.6 -3.6 -4.2 -4.1 3.9 -3.8 4.0 4.3 4.4 -1.2 4.2 4.4 -3.3 3.2 -0.5 -2.0 3.5 -3.8 3.9 3.6 3.9 3.8 2.5 3.9
Impedance of leg (left) 0.4 1.8 7.8 -2.7 -1.9 -2.3 0.1 -1.1 -1.5 -1.1 -0.9 -1.6 -0.9 -1.3 -1.4 -1.9 -1.7 -2.8 -1.5 -0.7 -1.1 0.5 -1.4 1.0 0.4 0.5 -1.2 0.7 0.1 -1.6 1.4 0.4 0.2 1.0 -1.3 1.1 1.1 1.2 1.0 1.0 1.2
Leg predicted mass (left) 0.6 3.4 13.9 2.5 2.4 1.1 0.8 1.9 2.0 1.2 2.2 3.2 1.4 2.0 2.2 2.7 1.5 3.7 2.4 1.5 1.6 1.0 2.4 -1.5 -1.4 -0.9 1.3 -0.9 0.4 1.7 -1.8 0.2 0.8 -1.6 2.2 -1.6 -2.2 -1.9 -1.4 -1.3 -1.9
Trunk fat mass 2.0 8.7 16.1 -2.7 1.1 -2.7 2.5 -3.3 -3.3 -3.7 -3.2 -1.5 -3.5 -2.9 -2.5 -2.1 -2.8 -1.4 -3.0 -3.6 -3.5 4.0 -3.0 3.4 3.4 3.8 -1.7 3.7 3.8 -3.1 2.5 -0.6 -1.6 2.8 -3.1 3.2 2.8 3.1 3.2 1.9 3.2
Waist circumference 0.5 1.9 5.6 -1.5 0.4 -2.4 0.8 -1.3 -1.5 -2.1 -1.4 -0.4 -1.6 -1.1 -1.1 -0.9 -1.7 -0.2 -1.5 -1.7 -1.6 2.0 -1.0 1.4 1.2 1.8 -1.3 1.5 1.9 -2.1 0.8 -0.8 -1.4 1.4 -1.2 1.2 0.5 1.1 1.2 0.7 1.1
Number of incorrect matches in round 1.0 1.6 3.2 0.9 0.1 1.0 -1.8 1.4 1.4 1.7 1.3 0.8 1.7 1.4 1.3 1.2 1.4 0.8 1.1 1.7 1.5 -1.1 1.3 -1.6 -1.6 -1.1 1.2 -1.7 -1.3 0.9 -1.1 0.2 0.8 -1.1 1.3 -1.4 -1.3 -1.3 -1.5 -0.5 -1.4
Past tobacco smoking 0.7 1.4 3.3 -0.3 1.6 -0.7 1.7 -1.3 -1.1 -1.1 -1.2 -0.4 -1.2 -1.0 -0.4 -0.6 0.6 -0.4 -0.6 -0.9 -1.2 1.7 -1.2 1.1 1.0 1.5 0.7 1.5 1.8 -0.2 1.5 0.5 1.3 1.0 -1.3 1.2 1.8 1.5 1.2 1.4 1.4
Alcohol usually taken with meals 0.2 0.3 1.4 1.2 1.1 1.0 -0.1 0.0 0.4 0.1 0.0 0.6 0.1 0.2 0.3 0.7 1.1 0.0 0.4 -0.2 0.1 -0.5 0.0 -0.1 0.1 0.4 0.6 0.2 0.6 0.4 -0.3 -0.4 -0.9 -0.5 0.2 -0.1 0.0 -0.2 -0.3 -0.6 -0.1
Nervous feelings 0.1 0.3 1.5 1.0 0.1 0.5 -0.3 0.5 0.2 0.9 0.5 -0.5 0.6 0.1 -0.1 0.2 -0.3 -0.0 0.1 0.6 0.6 -1.2 0.2 -0.5 -0.3 -0.8 0.7 -0.6 -0.5 0.1 0.1 0.4 1.0 -0.8 0.5 -0.5 0.1 -0.3 -0.6 -0.1 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.1 -0.9 -0.8 -0.3 0.3 -0.7 -0.9 -0.6 -0.4 -1.0 -0.9 -1.0 -1.0 -0.6 -0.6 -1.0 -0.6 -0.6 -0.6 0.5 -0.9 0.7 0.6 0.8 -0.4 0.7 0.4 -1.0 0.6 0.0 0.6 0.1 -0.3 0.8 0.8 0.6 0.7 0.5 0.7
Hearing difficulty/problems with background noise 0.4 0.6 8.4 1.4 1.9 2.9 -0.5 0.1 0.2 0.8 -0.1 0.4 0.4 0.3 0.7 0.5 1.5 0.5 0.5 -0.0 0.2 -0.8 -0.1 -0.1 0.4 0.2 1.4 -0.1 0.2 1.1 0.2 -0.4 0.0 -0.4 0.0 -0.1 0.1 -0.1 -0.4 -0.2 -0.0
Hair/balding pattern: Pattern 2 2.3 2.9 6.3 1.7 -0.4 0.9 -2.1 1.9 2.0 1.7 2.0 1.4 1.6 1.7 1.4 1.2 1.0 0.9 1.5 1.6 2.0 -1.8 1.7 -2.1 -1.7 -1.9 0.5 -1.7 -1.0 1.4 -2.3 -0.7 -0.1 -2.5 2.3 -2.0 -1.7 -2.2 -2.2 -2.0 -2.1
Had menopause 6.3 7.8 15.5 -2.8 -0.1 -1.3 1.0 -3.3 -3.4 -3.4 -3.9 -2.8 -3.0 -3.0 -2.8 -3.0 -1.2 -3.2 -3.2 -3.5 -3.2 0.6 -3.5 3.2 3.0 3.8 -1.7 3.0 2.6 -2.6 2.2 -1.7 -2.1 2.6 -3.4 2.8 3.2 3.1 2.8 1.6 3.1
Had other major operations 4.2 5.1 10.4 -1.4 0.7 -0.2 3.0 -2.5 -2.5 -1.8 -2.2 -1.9 -2.3 -2.4 -2.2 -1.8 -1.1 -1.4 -2.1 -2.4 -2.4 1.5 -2.6 2.7 2.9 3.2 -0.5 2.9 2.8 -1.9 2.8 0.8 0.1 2.9 -2.7 2.7 2.2 2.7 2.8 2.5 2.7
Forced vital capacity (FVC) 0.6 2.4 6.4 1.7 0.4 2.1 -0.1 1.8 1.7 1.3 1.8 1.8 1.1 1.3 1.5 0.4 1.9 1.3 2.0 1.4 1.8 -0.5 1.6 -1.6 -1.2 -0.8 -0.3 -0.9 -0.1 2.0 -2.4 -0.8 0.6 -2.5 2.0 -1.8 -1.3 -2.1 -1.5 -2.3 -1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.0 3.3 0.1 1.6 1.1 1.8 -1.0 -0.5 0.0 -0.6 0.0 -0.8 -0.6 -0.2 0.5 0.4 0.8 -0.2 -0.7 -0.9 1.5 -0.8 1.0 1.5 1.2 1.2 1.3 1.3 0.0 1.2 1.3 0.9 1.1 -0.8 1.3 1.2 1.2 1.2 1.3 1.2
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 4.1 -0.5 0.9 -0.3 0.5 -0.3 -0.5 0.4 0.2 -0.7 -0.1 -0.4 -0.5 0.6 -1.3 0.2 -0.5 -0.1 -0.4 0.7 -0.3 0.6 0.5 0.3 1.0 0.3 0.0 -1.4 1.6 1.9 0.7 1.5 -0.3 0.8 -0.0 0.8 0.5 2.0 0.7
Qualifications: None of the above 0.8 1.8 3.9 -1.7 0.3 -0.7 1.1 -1.7 -1.3 -1.6 -2.0 -1.1 -1.5 -1.2 -1.2 -1.0 -0.9 -0.5 -1.4 -1.4 -1.6 1.2 -1.5 1.6 1.5 1.5 -1.2 1.1 0.4 -1.0 1.0 -0.2 -0.7 1.7 -1.8 1.6 1.6 1.6 1.8 1.1 1.6
Financial difficulties in last 2 years 1.4 1.9 5.6 -2.4 -1.7 -1.8 0.8 -1.2 -1.7 -1.9 -1.1 -1.4 -1.7 -1.6 -1.8 -1.3 -1.7 -1.3 -1.3 -1.5 -1.4 1.5 -1.2 1.5 0.9 1.7 -1.7 1.3 1.1 -1.9 0.6 -0.3 -0.6 0.9 -1.1 1.3 1.1 1.0 1.5 0.4 1.2
Mouth/teeth dental problems 0.1 0.2 1.5 -0.3 -0.0 0.0 1.2 -0.2 -0.1 -0.3 -0.2 0.4 -0.2 -0.2 0.1 0.0 0.6 0.5 0.1 -0.4 -0.4 0.5 -0.2 0.4 0.5 0.3 0.2 0.7 1.0 0.0 0.1 0.3 -0.2 0.5 -0.2 0.3 -0.0 0.2 0.5 0.1 0.2
Heart attack 0.3 0.4 1.7 -0.8 -0.3 -0.5 -1.1 -0.5 -0.6 -0.7 -0.7 -0.8 -0.5 -0.6 -0.7 -0.4 -0.2 -1.3 -0.8 -0.8 -0.5 -0.5 -0.6 0.4 0.3 0.0 -0.4 0.1 -0.1 -0.6 0.2 -1.3 -1.0 0.1 -0.5 0.3 0.2 0.4 0.0 0.1 0.3
Allergy 8.1 18.6 49.8 3.0 4.8 3.9 -2.3 4.2 5.3 5.0 4.7 5.3 5.1 5.4 5.5 7.1 5.0 5.9 5.1 4.7 4.3 -2.5 5.0 -4.1 -4.1 -4.2 5.5 -4.1 -3.4 3.4 -2.6 2.4 1.9 -2.4 4.2 -3.8 -4.1 -3.7 -4.0 -1.2 -3.9
Pain all over the body in last month 1.1 1.1 3.2 -1.3 -0.6 -0.1 -0.0 -1.0 -1.1 -1.1 -1.2 -1.6 -1.2 -1.3 -1.5 -1.5 -0.8 -1.8 -1.1 -1.3 -1.0 0.1 -1.4 1.1 1.1 1.3 -1.2 1.1 1.3 -0.9 0.4 -1.3 -0.9 0.4 -1.0 0.7 0.8 0.8 0.7 0.2 0.8
Diabetes (self-reported) 2.3 3.6 9.1 -2.8 -0.4 -2.5 0.1 -2.0 -2.3 -2.3 -2.3 -2.2 -1.8 -1.9 -2.0 -1.7 -1.8 -1.9 -2.2 -1.8 -2.1 0.8 -2.0 1.9 1.3 2.0 -1.3 1.4 0.4 -3.0 2.1 -0.2 -0.7 2.1 -2.3 1.9 1.8 2.1 1.9 1.5 2.1
Hayfever/allergic rhinitis (self-reported) 5.0 6.6 12.4 -2.5 -2.1 -1.5 1.4 -2.8 -3.0 -2.9 -2.8 -2.9 -3.1 -3.2 -3.1 -3.5 -2.6 -3.1 -2.9 -3.1 -2.7 1.2 -3.1 2.7 2.7 3.1 -2.8 2.8 2.2 -2.4 1.3 -1.2 -1.8 1.8 -2.5 2.5 2.6 2.3 2.7 0.8 2.4
Medication: Ramipril 2.4 3.1 10.2 -2.3 -2.4 -1.7 -0.5 -1.5 -1.8 -2.0 -1.9 -2.4 -1.8 -2.1 -2.1 -3.2 -1.7 -2.6 -2.1 -1.9 -1.4 0.5 -1.9 1.6 1.5 2.0 -2.7 1.3 1.2 -1.8 0.4 -1.9 -1.0 0.2 -1.5 1.2 1.8 1.2 1.3 -0.1 1.3
Medication: Simvastatin 4.7 6.9 18.0 -2.9 -3.0 -2.8 -1.2 -2.5 -3.0 -2.8 -3.0 -3.7 -2.6 -3.0 -3.3 -4.2 -3.2 -4.1 -3.5 -2.8 -2.4 -0.3 -2.9 2.4 1.9 2.2 -3.7 1.6 0.4 -3.2 1.4 -2.2 -2.3 1.5 -2.4 2.1 2.1 2.1 1.9 0.6 2.2
Fluid intelligence score 0.3 0.7 3.9 1.1 -1.3 -0.3 -1.0 0.1 0.4 -0.3 -0.1 -0.4 -0.2 -0.3 -0.4 -0.8 -0.7 -0.7 -0.4 -0.3 0.3 -1.4 0.2 -0.2 -0.1 -1.2 -1.3 -0.4 -0.4 -0.0 -1.2 -2.0 -1.3 -1.4 0.4 -0.7 -0.1 -0.6 -0.8 -1.5 -0.5
Illnesses of siblings 3.0 4.3 7.3 2.1 0.9 0.9 -2.2 2.2 2.5 2.7 2.5 1.9 2.5 2.4 2.1 2.6 1.2 1.7 2.0 2.4 2.4 -2.1 2.3 -2.4 -2.5 -2.0 2.1 -2.4 -2.0 1.2 -1.4 0.9 0.3 -1.5 2.4 -2.1 -2.5 -2.1 -2.6 -0.9 -2.2
Neuroticism score 0.3 0.6 1.6 -0.3 0.2 0.5 0.3 -0.8 -0.9 -0.4 -0.7 -1.1 -1.0 -1.2 -1.0 -0.8 -0.7 -0.9 -1.0 -0.9 -0.7 0.3 -1.2 0.9 1.3 0.8 -0.2 0.9 1.1 -1.0 0.8 -0.3 0.4 0.2 -0.5 0.8 0.9 0.8 0.6 0.6 0.8
Weight 0.2 0.8 5.3 0.3 2.1 -0.8 1.5 -0.5 -0.5 -1.1 -0.3 1.0 -0.9 -0.2 0.0 0.5 -0.3 1.4 -0.1 -0.9 -0.8 2.3 -0.1 0.8 0.8 1.4 -0.0 1.2 2.1 -0.5 0.2 -0.2 -0.6 0.5 -0.2 0.6 0.0 0.4 0.7 0.1 0.4
Impedance of arm (right) 0.5 2.4 10.8 -1.9 -3.3 -2.5 -0.3 -1.2 -1.6 -1.5 -1.3 -2.4 -1.2 -1.7 -2.0 -2.4 -2.4 -2.9 -1.8 -1.1 -1.3 0.4 -1.6 1.1 0.8 0.9 -1.8 0.9 0.4 -1.2 0.9 -0.3 -0.4 0.7 -1.4 1.1 1.3 1.1 1.1 0.4 1.2
Arm fat percentage (right) 5.3 20.9 30.8 -4.3 0.2 -3.3 2.8 -5.4 -5.2 -5.2 -5.4 -3.9 -5.3 -5.0 -4.5 -4.1 -4.0 -3.5 -5.1 -5.5 -5.4 4.6 -5.2 5.2 5.5 5.5 -2.5 5.3 5.0 -4.7 4.1 -0.9 -2.7 4.5 -5.1 5.1 4.9 5.1 4.9 3.1 5.1
Trunk fat-free mass 2.0 11.7 27.3 4.0 2.7 1.6 -0.5 4.0 3.9 3.0 4.3 4.7 3.4 3.9 3.8 4.5 2.8 5.2 4.3 3.6 3.6 -0.7 4.5 -3.4 -3.6 -2.9 2.2 -2.9 -1.3 3.0 -3.4 0.6 1.2 -3.0 4.3 -3.5 -4.4 -3.9 -3.3 -2.4 -3.9
Hip circumference 0.3 1.1 5.3 -0.0 1.6 -0.1 1.5 -1.0 -0.9 -1.3 -1.0 0.4 -1.3 -0.7 -0.5 -0.3 -0.6 0.5 -0.7 -1.4 -1.2 2.0 -0.8 1.1 1.4 1.9 -0.3 1.6 2.3 -0.6 0.4 -0.5 -1.2 0.7 -0.8 1.0 0.6 0.8 1.0 0.2 0.8
Time employed in main current job 4.0 4.7 7.8 1.1 0.1 0.9 -2.7 2.4 2.5 1.6 2.1 1.9 2.1 2.4 1.9 1.8 1.1 1.5 1.9 2.1 2.4 -1.6 2.5 -2.4 -2.6 -2.8 0.1 -2.8 -2.3 1.2 -2.8 -1.4 -1.0 -2.7 2.4 -2.7 -2.5 -2.7 -2.8 -2.8 -2.7
Alcohol intake versus 10 years previously 0.4 0.6 6.2 -0.3 -1.0 -0.3 -2.5 0.4 0.4 0.4 0.1 -0.9 0.6 0.2 -0.1 -0.4 0.3 -0.5 -0.1 0.3 0.6 -2.0 0.2 -0.5 -0.8 -0.2 -0.3 -1.0 -1.4 -0.3 -0.7 -0.5 -1.1 -0.6 0.6 -0.6 -0.4 -0.6 -0.8 -0.7 -0.6
Father’s age at death 0.8 1.1 6.4 1.1 2.5 2.4 1.0 0.4 0.8 0.8 0.6 1.8 0.6 1.2 1.2 2.5 1.3 1.7 1.1 0.5 0.5 -0.1 1.0 -0.3 -0.2 -1.0 1.7 -0.4 -0.8 0.2 0.2 0.6 0.8 0.2 0.3 -0.3 -0.6 -0.1 -0.2 0.5 -0.3
Worrier / anxious feelings 1.1 2.2 5.0 -1.6 0.1 -0.8 0.9 -1.5 -1.7 -1.2 -1.5 -2.2 -1.4 -1.9 -2.0 -1.6 -1.5 -1.3 -1.8 -1.5 -1.4 0.9 -1.7 1.4 1.8 1.8 -0.8 1.6 2.1 -1.9 1.3 -0.4 0.2 0.9 -1.4 1.4 1.8 1.5 1.3 1.1 1.5
Frequency of tiredness / lethargy in last 2 weeks 3.3 5.4 9.6 -1.4 0.2 -1.3 1.6 -2.7 -2.7 -1.9 -2.4 -2.6 -2.5 -2.6 -2.4 -1.6 -2.0 -1.4 -2.4 -2.4 -2.6 2.1 -2.6 2.8 2.7 2.7 -0.2 2.4 1.4 -2.3 3.1 1.2 0.1 2.9 -2.6 2.9 2.7 3.0 2.8 2.7 2.9
Falls in the last year 1.5 2.0 4.8 -1.7 -1.3 -2.0 -0.3 -1.4 -1.6 -1.4 -1.4 -1.7 -1.3 -1.6 -1.8 -1.9 -2.2 -2.1 -1.9 -1.5 -1.3 0.1 -1.5 1.2 1.0 1.2 -1.7 1.0 0.6 -2.0 0.9 -0.9 -1.5 1.3 -1.1 1.1 0.7 1.2 0.9 0.8 1.1
Hair/balding pattern: Pattern 3 0.1 0.2 1.9 -0.4 -0.1 -0.9 -0.2 0.1 -0.4 -0.6 -0.6 -0.4 -0.3 -0.3 -0.4 -1.2 -0.3 -0.4 -0.4 -0.1 -0.1 -0.3 -0.1 0.0 -0.2 0.7 -1.4 0.1 0.0 -0.3 -0.2 -0.9 -0.5 0.1 -0.4 -0.3 -0.2 -0.0 -0.0 -0.4 -0.1
Number of live births 3.2 4.5 10.0 -3.0 -1.7 -2.0 0.0 -2.2 -2.3 -2.4 -2.5 -3.2 -2.1 -2.4 -3.0 -2.7 -2.4 -3.1 -2.8 -2.3 -2.0 0.5 -2.4 2.0 1.8 1.8 -2.5 1.8 1.5 -2.4 0.9 -1.9 -1.9 1.1 -2.1 1.7 2.1 1.7 1.6 0.4 1.8
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 2.7 0.2 0.1 -0.6 0.4 0.7 0.4 -0.4 0.7 0.8 -0.1 0.2 0.3 -0.3 0.6 0.5 0.7 0.2 0.4 1.1 0.6 -0.4 -0.5 0.2 -0.9 0.2 1.3 0.1 -1.4 -0.8 -0.0 -1.5 0.9 -0.6 -0.3 -1.0 -0.4 -1.6 -0.8
Pulse rate 0.4 0.6 2.5 -0.9 -1.2 -0.5 -1.6 0.4 0.4 -0.1 0.0 -0.5 0.1 0.1 -0.3 -0.3 -0.6 -0.6 -0.2 0.2 0.5 -1.5 0.4 -0.5 -0.7 -0.9 -1.1 -0.9 -1.4 -0.6 -1.0 -1.6 -0.7 -0.7 0.3 -0.7 -0.7 -0.6 -0.7 -0.9 -0.7
Happiness 0.5 0.6 3.6 0.6 0.9 0.6 0.1 0.4 0.8 1.3 0.9 0.7 0.8 0.8 0.9 1.6 0.8 1.1 0.6 0.7 0.4 -0.6 0.5 -0.6 -0.2 -0.7 1.9 -0.5 -0.9 0.2 0.6 1.8 0.9 0.3 0.5 -0.1 -0.4 -0.1 -0.4 0.7 -0.1
Noisy workplace 0.4 0.5 2.4 0.3 0.7 1.1 -0.1 0.9 0.5 1.0 0.9 0.6 0.8 0.7 0.8 0.2 0.8 0.9 1.0 1.1 0.9 -0.1 0.7 -0.6 -0.7 0.2 0.5 -0.6 -0.1 0.5 -0.5 0.3 1.5 -0.8 0.9 -0.7 -0.7 -0.8 -0.6 -0.2 -0.8
Qualifications: A levels/AS levels or equivalent 0.6 1.4 3.8 0.2 -0.8 -0.2 -0.1 -1.4 -1.1 -1.2 -1.4 -1.1 -1.6 -1.5 -1.4 -1.5 -1.4 -1.9 -1.7 -1.8 -1.2 0.4 -1.6 1.3 1.5 0.6 -1.2 1.3 1.1 -1.1 0.4 -1.6 -1.7 0.5 -0.7 1.1 0.8 0.9 0.6 0.3 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 2.7 1.4 -0.4 0.4 -0.0 0.7 0.4 0.8 0.8 -0.1 0.6 0.4 0.3 0.6 0.4 0.7 0.5 0.8 0.6 0.1 0.6 -0.5 -0.5 -0.6 1.3 -0.5 -0.4 0.7 0.3 0.9 1.6 -0.4 0.7 -0.4 -0.5 -0.3 -0.5 0.3 -0.4
Mouth/teeth dental problems: Dentures 0.8 1.3 5.7 -1.6 -2.1 -2.3 -0.4 -0.7 -1.0 -1.4 -0.8 -1.6 -1.0 -1.1 -1.5 -1.7 -1.9 -1.6 -1.3 -0.9 -0.8 0.2 -0.9 0.9 0.3 0.5 -2.4 0.3 -0.1 -1.5 -0.1 -0.8 -1.2 -0.1 -0.6 0.4 0.9 0.4 0.7 -0.7 0.5
Asthma 7.0 13.8 25.5 -3.3 -2.9 -2.8 1.5 -4.1 -4.3 -3.9 -4.4 -5.1 -4.1 -4.6 -4.8 -4.7 -4.4 -4.6 -4.4 -4.2 -4.0 2.2 -4.4 3.9 3.9 3.4 -3.1 3.6 2.3 -3.3 3.1 -1.3 -1.7 3.0 -4.1 3.8 4.0 3.8 3.8 2.1 3.9
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.6 -0.3 -1.6 -0.8 -1.3 0.9 0.6 0.0 0.9 0.1 0.5 0.4 0.0 0.1 -0.7 -0.4 0.2 0.5 0.8 -1.1 0.7 -0.9 -1.3 -1.2 -1.1 -1.0 -1.4 -0.2 -1.4 -1.0 -0.5 -1.4 1.0 -1.0 -0.9 -1.2 -1.0 -1.5 -1.1
Medication: Cholesterol lowering 5.9 9.2 19.6 -3.0 -2.6 -4.3 0.2 -3.1 -3.5 -3.8 -3.5 -3.8 -3.3 -3.6 -3.6 -4.4 -3.0 -4.3 -3.7 -3.4 -3.1 1.0 -3.4 3.0 2.3 3.4 -3.4 2.7 1.9 -3.0 1.8 -1.6 -2.4 2.1 -3.0 2.7 2.8 2.7 2.7 1.0 2.7
Depression (self-reported) 0.2 0.2 2.4 0.6 0.5 -0.0 0.7 -0.2 -0.3 0.2 0.3 -0.0 0.0 -0.0 0.1 0.5 0.2 0.4 0.2 0.2 -0.2 0.5 -0.1 0.0 -0.1 0.7 1.1 0.3 0.2 0.3 0.7 1.6 0.8 0.6 -0.1 0.4 0.0 0.3 0.4 0.8 0.3
Medication: Lansoprazole 1.2 1.4 2.5 -1.4 -0.6 -0.2 0.5 -1.3 -1.4 -1.1 -1.4 -1.3 -1.3 -1.4 -1.3 -1.1 -0.6 -1.6 -1.1 -1.4 -1.4 0.3 -1.5 1.4 1.3 1.5 -0.5 1.3 0.8 -1.1 1.3 -0.0 -0.3 1.2 -1.3 1.4 1.1 1.3 1.4 0.9 1.4
Prospective memory result 1.2 1.4 6.1 -1.2 2.3 0.2 2.5 -0.9 -0.8 -0.7 -0.9 0.6 -0.8 -0.4 0.0 0.5 0.1 0.7 -0.3 -0.6 -1.0 2.2 -0.6 1.1 1.2 1.5 0.7 1.6 2.3 -0.7 1.4 1.1 0.4 1.4 -1.3 1.1 1.1 1.2 1.4 1.1 1.2
Lung cancer (father) 1.5 1.8 3.3 1.3 1.3 -0.0 -0.2 1.5 1.4 1.5 1.8 1.7 1.8 1.6 1.7 1.6 1.2 1.7 1.5 1.8 1.3 -0.4 1.6 -1.6 -1.7 -0.8 1.4 -1.1 -0.5 0.8 -0.6 1.5 1.4 -1.1 1.4 -1.3 -0.9 -1.2 -1.3 -0.4 -1.2
Illnesses of mother 0.2 0.2 1.0 -0.0 0.7 -0.4 -0.4 0.2 0.6 0.5 0.5 -0.1 0.5 0.4 0.2 0.9 -0.3 0.7 0.3 0.4 0.4 -1.0 0.5 -0.4 -0.4 -0.3 0.3 -0.3 -0.9 -0.5 -0.2 0.6 -0.3 0.2 0.4 -0.2 -0.5 -0.3 -0.3 0.2 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 2.2 -0.2 -0.2 -1.2 -0.1 0.2 -0.1 -0.7 0.3 0.1 -0.4 -0.3 -0.1 -0.9 0.2 -0.1 0.1 -0.1 0.0 1.2 0.1 -0.0 -0.3 0.6 -1.1 0.4 1.5 -0.3 -1.1 -1.0 -0.4 -1.2 0.6 -0.3 0.1 -0.6 -0.2 -1.4 -0.4
Pulse wave Arterial Stiffness index 0.8 1.0 3.0 -1.1 0.5 -0.7 0.6 -1.0 -1.2 -1.7 -1.3 -0.5 -1.4 -1.0 -1.0 -0.8 -0.5 -0.6 -0.8 -1.5 -1.3 0.6 -1.0 1.2 0.9 0.9 -1.1 1.1 0.8 -0.6 0.6 -1.2 -1.4 0.7 -1.2 0.9 0.8 0.9 1.0 -0.1 1.0
Impedance of arm (left) 0.4 1.9 9.4 -1.7 -3.1 -1.6 -0.3 -1.2 -1.4 -1.2 -1.2 -2.1 -1.2 -1.6 -1.7 -2.2 -1.9 -2.8 -1.5 -1.1 -1.2 0.2 -1.6 1.0 0.8 0.6 -1.5 0.8 -0.1 -1.0 0.8 -0.4 -0.0 0.4 -1.3 1.1 1.6 1.1 1.1 0.3 1.1
Arm fat mass (right) 2.5 10.4 17.5 -2.8 1.2 -2.6 2.5 -3.7 -3.6 -3.9 -3.6 -2.0 -3.9 -3.3 -2.9 -2.4 -2.7 -1.6 -3.4 -4.0 -3.9 4.1 -3.5 3.7 3.9 4.2 -1.6 4.0 4.1 -3.3 2.8 -0.6 -2.0 3.2 -3.5 3.6 3.2 3.5 3.5 2.1 3.5
Trunk predicted mass 2.0 11.2 26.0 3.9 2.7 1.5 -0.5 3.9 3.9 2.9 4.2 4.6 3.3 3.9 3.7 4.4 2.7 5.1 4.1 3.5 3.5 -0.6 4.4 -3.4 -3.5 -2.8 2.2 -2.7 -1.2 2.9 -3.3 0.6 1.1 -2.9 4.2 -3.4 -4.4 -3.8 -3.3 -2.4 -3.8
Standing height 3.6 35.3 58.2 6.1 0.7 1.8 -2.7 7.3 6.8 5.3 7.6 6.8 6.3 6.7 6.2 6.1 4.2 6.2 7.0 6.7 6.7 -3.0 7.6 -6.6 -7.2 -6.2 2.5 -6.1 -4.3 5.6 -6.3 0.4 2.5 -6.2 7.3 -6.7 -7.5 -7.2 -6.4 -5.1 -7.2
Length of working week for main job 0.7 0.8 1.4 0.3 0.7 0.4 -0.6 1.1 0.9 0.7 1.0 1.2 0.9 1.1 0.9 0.9 0.3 0.8 1.0 1.0 1.1 0.4 1.1 -1.2 -1.1 -0.3 0.3 -0.7 0.3 0.7 -1.1 -0.7 0.7 -1.1 1.1 -1.0 -1.1 -1.1 -1.1 -0.6 -1.1
Exposure to tobacco smoke at home 3.1 3.5 6.2 -1.8 -1.0 -2.4 1.4 -1.9 -2.3 -2.4 -1.9 -2.1 -2.3 -2.3 -2.4 -2.5 -1.8 -2.1 -2.0 -2.0 -2.2 1.1 -2.2 2.1 1.8 1.9 -2.0 1.7 1.4 -1.6 1.4 -0.6 -0.8 1.4 -1.9 1.8 1.8 1.8 2.1 0.5 1.9
Breastfed as a baby 0.5 0.7 3.1 1.1 -0.3 0.3 -1.8 0.7 0.8 1.0 0.8 -0.1 1.0 0.7 0.4 0.3 0.3 -0.1 0.4 0.7 0.9 -1.5 0.7 -0.9 -0.8 -0.7 0.1 -1.1 -1.2 0.7 -0.8 -0.3 -0.2 -0.9 0.9 -0.8 -0.6 -0.8 -1.1 -0.5 -0.8
Tense / ‘highly strung’ 0.1 0.1 1.6 -0.3 0.1 0.3 0.6 -0.1 -0.2 0.1 -0.1 -0.3 -0.0 -0.2 -0.3 -0.5 0.1 -0.4 -0.2 0.0 0.1 0.2 -0.5 0.1 0.2 0.8 -0.1 0.5 1.3 0.0 0.1 0.0 0.8 -0.2 0.0 0.1 0.3 0.1 0.1 0.1 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.3 3.2 -1.3 -0.7 -0.5 -0.4 -1.2 -1.4 -1.0 -1.2 -1.8 -1.0 -1.3 -1.3 -1.0 -1.5 -1.5 -1.6 -1.2 -1.1 0.7 -1.4 1.1 1.1 1.5 -0.3 1.1 0.8 -1.3 1.0 -0.2 -0.4 0.7 -1.2 1.0 1.4 1.2 0.9 0.8 1.2
Hair/balding pattern: Pattern 4 0.4 1.0 6.5 1.2 1.7 2.5 1.2 0.3 0.7 1.2 0.5 1.2 0.9 0.9 1.1 1.6 1.2 1.7 1.0 0.8 0.4 0.4 0.6 -0.4 -0.0 -0.5 1.8 -0.3 -0.3 1.2 0.4 1.8 1.1 0.3 0.2 0.0 -0.0 -0.0 0.1 0.5 -0.0
Birth weight of first child 3.1 5.6 11.8 2.0 1.0 0.2 -1.9 2.7 2.8 2.3 2.9 2.5 2.9 2.7 2.4 3.4 1.2 2.5 2.6 2.6 2.6 -1.4 3.0 -2.8 -2.9 -2.6 2.2 -2.4 -1.7 1.7 -2.0 1.0 -0.5 -1.8 2.8 -2.5 -3.1 -2.6 -2.7 -1.6 -2.6
Peak expiratory flow (PEF) 0.5 1.3 2.8 1.5 -0.1 -0.4 -0.3 1.4 1.2 0.5 1.4 1.2 1.1 1.0 1.0 1.1 1.0 1.5 1.4 1.1 1.1 0.7 1.4 -1.1 -1.2 -1.1 0.5 -0.7 0.2 1.2 -1.5 -0.4 0.9 -1.7 1.4 -1.2 -1.1 -1.5 -1.1 -1.3 -1.3
Pulse wave reflection index 3.4 4.1 7.3 -2.3 0.3 -1.6 2.0 -2.2 -2.5 -2.7 -2.2 -1.5 -2.5 -2.2 -2.0 -1.8 -1.6 -1.4 -1.8 -2.5 -2.6 2.3 -2.2 2.4 2.2 2.2 -1.4 2.6 2.7 -1.3 1.6 -0.3 -1.8 1.9 -2.2 2.2 2.1 2.0 2.3 0.7 2.2
Ever highly irritable/argumentative for 2 days 2.3 2.8 6.3 -1.7 -0.3 -2.5 0.7 -1.8 -2.0 -1.6 -1.4 -2.0 -1.6 -1.9 -1.8 -1.8 -1.8 -1.9 -1.9 -1.7 -1.8 1.3 -1.9 1.7 1.4 2.1 -0.9 1.7 1.8 -2.0 1.6 0.3 -0.2 1.7 -1.5 1.8 1.6 1.8 1.6 1.6 1.8
Loud music exposure frequency 0.2 0.2 1.5 0.0 1.2 0.8 -0.4 -0.2 0.1 0.1 0.1 0.1 -0.1 -0.0 0.2 1.0 0.2 0.3 0.3 -0.1 -0.1 0.2 0.1 0.3 0.1 0.5 1.1 0.2 0.6 -0.0 0.1 0.0 0.2 -0.5 -0.0 0.2 0.8 0.2 0.0 -0.0 0.3
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 2.8 -0.3 -0.4 -0.7 -0.0 -0.4 -0.6 -0.6 -0.8 -0.7 -0.4 -0.7 -0.8 -1.6 -1.0 -1.0 -1.0 -0.5 -0.3 -0.2 -0.6 0.2 0.4 0.1 -1.3 0.3 0.8 -0.6 -0.1 -1.7 0.3 -0.3 -0.4 0.1 0.6 0.3 0.0 0.1 0.2
Mouth/teeth dental problems: Bleeding gums 0.1 0.2 0.8 0.7 0.9 0.6 -0.7 -0.4 -0.2 0.3 -0.4 -0.5 0.1 -0.2 -0.1 -0.1 0.2 -0.5 -0.4 -0.1 -0.1 -0.7 -0.5 0.0 0.1 0.4 0.6 0.1 -0.1 0.2 0.5 0.1 0.2 -0.0 -0.1 0.3 0.7 0.4 -0.0 0.6 0.4
Blood clot in the leg (DVT) 0.9 1.1 5.3 -0.3 -1.9 -1.8 -0.1 -0.8 -1.4 -0.9 -0.8 -1.6 -0.8 -1.2 -1.4 -2.3 -1.1 -1.6 -1.4 -0.9 -0.9 -0.2 -1.2 0.8 0.6 0.9 -1.5 0.4 0.2 -1.3 0.9 0.1 -0.1 0.3 -0.8 0.8 1.0 0.8 0.7 0.2 0.9
Medication: Paracetamol 1.4 2.4 9.8 -2.5 -2.4 -3.1 -0.3 -1.2 -1.5 -2.0 -1.2 -2.2 -1.4 -1.6 -2.2 -1.9 -2.4 -1.8 -1.8 -1.3 -1.2 0.2 -1.2 1.2 0.5 1.0 -2.5 0.7 0.2 -2.5 0.2 -0.8 -1.2 0.8 -0.9 1.0 0.7 0.8 1.2 0.0 0.8
Headache pain in last month 3.2 5.5 17.3 -2.6 2.0 -2.4 1.9 -2.6 -2.5 -2.8 -2.5 -1.3 -2.4 -2.2 -1.9 -1.0 -2.0 -1.2 -2.3 -2.7 -2.7 2.9 -2.5 2.6 2.4 3.0 -0.1 3.0 4.2 -2.4 2.4 -0.3 -1.6 2.3 -2.5 2.6 2.3 2.5 2.2 1.6 2.6
Medication for cholesterol, blood pressure or diabetes 3.8 6.2 21.5 2.8 3.9 3.5 0.4 2.0 2.8 3.1 2.6 3.0 2.6 3.0 2.9 4.6 2.7 4.1 3.0 2.5 2.1 -0.4 2.5 -2.0 -1.5 -2.6 4.0 -1.8 -1.1 2.2 -0.6 2.1 2.0 -0.8 2.2 -1.5 -2.1 -1.6 -1.8 0.3 -1.7
Glaucoma (self-reported) 2.0 2.4 6.6 2.0 0.3 1.8 -1.1 1.4 1.9 1.8 1.1 1.2 1.6 1.5 1.8 0.9 2.4 1.5 1.7 1.7 1.7 -1.0 1.5 -1.8 -1.2 -1.7 1.2 -1.6 -1.7 2.6 -1.7 -0.3 1.4 -1.5 1.5 -1.6 -1.2 -1.5 -1.5 -0.8 -1.6
Gout (self-reported) 0.3 0.4 1.9 1.0 0.3 0.7 -0.1 0.5 0.8 0.9 0.6 0.6 0.7 0.7 0.7 1.0 0.1 1.4 0.7 0.7 0.6 -0.6 0.9 -0.4 -0.3 -0.7 0.7 -0.6 -1.0 0.5 -0.3 0.8 0.4 -0.3 0.5 -0.3 -0.5 -0.5 -0.3 -0.2 -0.5
Hypothyroidism/myxoedema (self-reported) 1.6 3.2 7.2 -2.7 0.1 -2.6 0.9 -1.9 -2.2 -2.3 -1.9 -1.7 -1.7 -1.8 -1.8 -1.5 -1.5 -1.7 -2.0 -1.9 -2.1 1.5 -2.0 1.9 1.5 1.7 -0.9 1.8 1.9 -2.2 1.6 -0.3 -1.3 2.0 -2.0 1.8 1.6 1.9 1.8 1.4 1.8
Medication: Amlodipine 2.3 3.3 11.7 -2.6 -2.8 -1.9 -0.7 -1.3 -1.9 -2.1 -1.9 -2.5 -1.7 -2.1 -2.4 -3.3 -2.1 -3.1 -2.1 -1.7 -1.3 -0.5 -1.8 1.3 1.0 1.3 -3.4 0.8 0.7 -1.9 0.1 -2.4 -1.9 0.5 -1.3 0.7 0.8 0.8 0.8 -0.4 0.8
Medication: Ventolin 100micrograms inhaler 3.6 4.6 10.2 -2.2 -2.4 -1.6 0.4 -2.3 -2.3 -2.6 -2.6 -2.4 -2.5 -2.4 -2.5 -3.2 -2.0 -2.9 -2.7 -2.6 -2.1 1.3 -2.5 2.1 2.1 2.2 -2.9 2.0 2.0 -1.7 0.6 -1.9 -2.1 1.2 -2.0 1.7 2.0 1.7 1.8 0.2 1.8
Birth weight 0.9 1.9 5.0 1.2 2.2 -0.5 0.2 1.4 1.1 1.3 2.0 2.0 1.3 1.6 1.7 2.0 1.2 2.2 1.6 1.5 1.1 0.6 1.6 -1.0 -1.6 -1.0 2.1 -1.1 -0.6 0.4 0.1 1.9 1.9 -0.3 1.6 -0.9 -1.6 -0.9 -1.0 0.5 -1.0
Chronic bronchitis/emphysema (mother) 1.0 1.2 4.1 -1.3 -1.3 -1.1 -0.0 -1.0 -1.3 -0.9 -0.8 -1.5 -1.0 -1.3 -1.5 -1.7 -1.2 -2.0 -1.4 -1.1 -0.9 0.5 -1.3 0.7 0.8 1.3 -1.2 0.9 1.2 -1.2 0.6 -0.3 -0.9 0.5 -0.7 0.9 0.9 0.8 0.7 0.3 0.9
High blood pressure (siblings) 3.6 5.2 9.5 -2.7 -0.3 -1.8 2.0 -2.4 -2.8 -3.1 -2.6 -2.2 -2.6 -2.5 -2.3 -3.0 -1.7 -1.9 -2.4 -2.5 -2.6 2.5 -2.5 2.5 2.2 2.7 -2.7 2.5 2.5 -1.8 1.2 -1.2 -0.5 1.6 -2.5 2.2 2.6 2.2 2.6 0.8 2.2
Forced vital capacity (FVC), Best measure 0.3 0.9 3.8 1.1 -0.1 1.2 0.0 1.1 0.9 0.7 1.0 1.0 0.4 0.5 0.8 -0.4 1.3 0.6 1.1 0.8 1.1 0.3 0.8 -0.8 -0.6 -0.2 -0.5 -0.4 0.6 1.3 -1.7 -0.7 0.6 -1.9 1.3 -1.1 -0.5 -1.3 -0.8 -1.8 -1.2
Body fat percentage 5.6 22.0 32.4 -4.7 0.7 -3.4 3.4 -5.5 -5.3 -5.4 -5.5 -3.6 -5.5 -5.0 -4.4 -4.0 -4.1 -3.4 -5.1 -5.6 -5.5 5.0 -5.3 5.4 5.5 5.7 -2.6 5.5 5.2 -4.9 4.3 -0.8 -2.4 4.6 -5.3 5.2 5.1 5.2 5.2 3.3 5.3
Leg fat percentage (right) 6.7 24.4 36.1 -5.3 1.0 -3.2 3.9 -5.8 -5.6 -5.6 -5.9 -3.7 -5.7 -5.2 -4.6 -4.1 -3.8 -3.5 -5.3 -5.8 -5.8 5.0 -5.5 5.6 5.8 6.0 -2.5 5.8 5.5 -5.2 4.7 -0.8 -2.3 5.1 -5.7 5.6 5.3 5.6 5.5 3.7 5.6
Arm fat-free mass (right) 1.4 7.1 20.5 3.2 3.1 1.5 0.4 3.0 2.9 2.2 3.3 4.2 2.4 3.1 3.2 3.8 2.5 4.5 3.4 2.6 2.6 0.0 3.4 -2.5 -2.5 -1.9 2.0 -1.9 -0.6 2.3 -2.4 0.7 1.2 -2.1 3.1 -2.5 -3.2 -2.8 -2.3 -1.6 -2.8
Exposure to tobacco smoke outside home 1.1 1.5 3.2 1.8 0.4 0.2 -1.8 1.3 1.3 1.0 1.3 0.2 1.2 1.0 0.6 0.5 0.8 0.6 1.1 1.2 1.3 -1.5 1.3 -1.4 -1.4 -1.4 0.0 -1.5 -1.2 1.6 -1.4 -0.3 -1.0 -1.4 1.3 -1.3 -1.3 -1.5 -1.5 -1.6 -1.4
Comparative body size at age 10 3.8 10.6 17.1 -2.7 0.4 -2.0 3.8 -3.5 -3.8 -3.2 -3.3 -2.5 -3.6 -3.5 -3.0 -2.6 -2.3 -1.8 -3.2 -3.4 -3.6 4.0 -3.5 3.8 3.7 3.9 -1.0 4.1 3.9 -3.1 3.6 1.0 0.2 3.8 -3.7 3.7 3.5 3.8 3.9 3.4 3.7
Number of full brothers 2.0 2.6 15.5 -2.1 -1.8 -3.9 1.1 -1.3 -1.7 -2.3 -1.0 -1.9 -1.6 -1.8 -2.0 -1.8 -2.3 -1.7 -1.7 -1.5 -1.6 0.8 -1.4 1.3 0.7 0.9 -2.1 1.3 0.6 -2.3 0.7 -0.3 -0.8 1.2 -1.2 1.3 1.0 1.2 1.5 0.6 1.2
Worry too long after embarrassment 0.1 0.2 1.2 -0.2 -0.5 1.1 0.1 -0.1 -0.3 -0.0 -0.4 -0.6 -0.5 -0.5 -0.5 -0.7 0.4 -0.1 -0.1 -0.4 -0.2 -0.7 -0.4 0.3 0.7 0.1 -0.4 0.1 -0.1 -0.6 -0.0 -0.3 0.2 -0.1 -0.0 0.2 0.2 0.1 0.3 -0.1 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.5 0.4 -1.4 -0.6 -1.6 0.7 0.5 0.2 0.5 0.2 0.5 0.5 0.3 0.0 0.0 -0.2 0.1 0.5 0.6 -0.8 0.6 -0.7 -1.0 -0.4 -0.3 -1.0 -1.3 0.2 -0.7 -0.7 -0.4 -0.6 0.5 -0.8 -0.9 -0.8 -0.9 -0.7 -0.8
Wheeze or whistling in the chest in last year 2.0 3.6 8.8 -2.7 -2.0 -1.4 -1.1 -1.8 -1.9 -2.1 -2.2 -2.7 -1.8 -2.1 -2.5 -2.6 -2.7 -3.0 -2.4 -2.2 -1.6 -0.1 -2.0 1.6 1.5 1.4 -2.8 1.2 0.8 -2.0 0.3 -2.7 -2.1 0.5 -1.6 1.2 1.5 1.2 1.0 -0.1 1.3
Number of children fathered 0.1 0.1 0.9 -0.6 0.2 0.7 0.2 0.3 0.2 0.4 0.3 0.5 0.2 0.3 0.3 0.4 -1.0 0.1 -0.0 0.3 0.2 0.5 0.3 -0.2 0.1 -0.1 -0.2 -0.1 0.7 -0.2 -0.1 -0.1 -0.4 0.3 0.2 -0.3 -0.8 -0.2 -0.3 0.0 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 2.6 3.1 7.1 1.8 -0.2 2.7 -1.8 1.9 1.9 2.0 1.5 2.2 1.8 1.9 2.0 1.2 1.6 0.7 1.7 1.6 2.1 -1.5 1.6 -1.9 -1.4 -1.3 0.8 -1.5 -0.8 2.6 -1.8 -0.8 -0.5 -2.2 1.8 -2.1 -1.8 -2.0 -2.2 -2.1 -2.0
Age at first live birth 1.4 2.5 4.4 2.0 -0.1 1.6 -0.6 1.8 1.9 1.6 1.5 1.8 1.6 1.7 1.7 1.6 1.9 1.9 1.9 1.8 1.7 -1.1 1.9 -1.7 -1.5 -1.7 1.4 -1.7 -1.5 2.1 -1.2 0.2 0.9 -1.2 1.4 -1.7 -1.7 -1.6 -1.4 -1.1 -1.6
Pulse wave peak to peak time 1.6 1.9 4.6 1.6 -0.4 1.0 -0.7 1.5 1.7 2.1 1.7 0.9 1.8 1.5 1.4 1.2 0.8 1.1 1.3 1.9 1.8 -0.7 1.5 -1.6 -1.3 -1.4 1.3 -1.5 -1.1 1.1 -1.0 1.2 1.6 -1.1 1.7 -1.3 -1.2 -1.4 -1.4 -0.2 -1.4
Health satisfaction 1.5 2.0 3.5 -1.7 -0.8 -0.9 0.7 -1.5 -1.6 -1.2 -1.6 -1.7 -1.5 -1.7 -1.5 -1.5 -1.1 -1.7 -1.6 -1.4 -1.5 0.8 -1.7 1.4 1.5 1.9 -0.5 1.5 1.2 -1.6 1.5 0.3 -0.2 1.4 -1.5 1.5 1.6 1.6 1.4 1.2 1.6
Shortness of breath walking on level ground 1.9 2.3 4.2 -1.8 -0.6 -1.3 1.3 -1.6 -1.9 -1.5 -1.5 -1.7 -1.8 -1.8 -1.7 -1.8 -1.4 -1.5 -1.6 -1.6 -1.5 1.7 -1.8 1.5 1.6 1.9 -0.9 1.8 2.0 -1.5 1.4 0.0 -0.3 1.4 -1.3 1.6 1.3 1.5 1.5 1.1 1.5
Qualifications: College or University degree 0.1 0.4 4.5 1.0 1.3 2.1 -0.1 0.0 0.3 0.3 0.1 0.8 -0.1 0.2 0.4 1.1 0.5 -0.0 0.5 -0.2 0.1 0.4 0.2 -0.2 0.3 -0.7 1.2 -0.0 0.4 0.8 0.1 -0.9 -0.2 -0.7 0.2 -0.1 -0.1 -0.2 -0.5 -0.4 -0.1
Eye problems/disorders: None of the above 0.4 0.4 1.4 -0.3 -0.4 -0.5 1.2 -0.3 -0.8 -0.4 -0.2 -0.3 -0.7 -0.6 -0.7 -0.5 -1.0 -0.1 -0.4 -0.5 -0.6 0.6 -0.4 0.6 0.6 0.4 -0.5 0.6 -0.1 -1.1 1.0 0.8 0.5 1.0 -0.4 0.8 0.1 0.6 0.9 0.9 0.6
Mouth/teeth dental problems: Loose teeth 2.0 2.4 5.6 2.0 2.0 0.6 0.0 1.8 1.5 1.8 1.8 1.5 2.1 1.9 1.6 2.2 1.1 2.4 1.9 2.0 1.5 -0.5 1.9 -1.4 -1.6 -1.3 2.0 -1.5 -1.0 1.1 -0.2 1.6 1.9 -0.6 1.5 -1.3 -1.7 -1.2 -1.3 0.1 -1.3
Emphysema/chronic bronchitis 0.3 0.3 2.0 0.5 0.5 -0.7 1.4 -0.2 -0.3 -0.3 -0.2 0.3 -0.1 -0.1 0.0 0.4 0.6 0.7 0.1 -0.0 -0.5 0.7 -0.0 0.4 0.1 0.1 0.5 0.5 0.3 -0.3 0.7 0.8 1.4 0.8 -0.5 0.6 0.2 0.5 0.7 1.0 0.5
Medication for pain relief, constipation, heartburn 4.4 7.5 16.0 3.9 1.9 4.0 -0.7 2.8 3.2 3.7 2.9 3.4 3.0 3.2 3.6 3.0 3.4 3.3 3.3 2.9 2.9 -0.9 2.8 -2.7 -1.9 -2.7 3.2 -2.3 -1.5 3.8 -1.5 1.4 1.8 -2.0 2.7 -2.5 -2.4 -2.4 -2.7 -0.9 -2.4
Neck or shoulder pain in last month 1.6 2.3 5.5 -1.6 0.2 -0.9 1.1 -1.7 -1.8 -1.5 -1.6 -1.4 -1.6 -1.8 -1.6 -1.2 -1.1 -1.5 -1.6 -1.8 -1.6 1.4 -1.9 1.7 1.8 2.0 -0.4 2.0 2.3 -1.2 1.5 -0.1 -0.3 1.0 -1.4 1.7 1.9 1.6 1.5 0.9 1.7
Medication: Blood pressure 2.1 3.8 12.3 -2.2 -3.5 -2.4 -0.6 -1.5 -2.1 -2.2 -1.9 -2.7 -2.0 -2.4 -2.4 -3.5 -2.5 -3.1 -2.4 -1.9 -1.5 0.2 -1.9 1.6 1.2 1.7 -2.9 1.2 0.3 -2.0 0.7 -1.6 -1.3 0.6 -1.7 1.1 1.7 1.3 1.4 -0.0 1.4
Angina (self-reported) 4.4 5.8 9.0 -2.0 0.4 -0.9 1.1 -2.9 -2.9 -2.6 -3.0 -2.2 -2.7 -2.6 -2.4 -2.7 -2.1 -2.7 -2.8 -2.9 -2.8 2.2 -2.9 2.6 2.9 2.8 -1.9 2.8 2.4 -1.9 2.3 -1.1 -0.9 2.0 -2.8 2.6 2.9 2.7 2.4 1.6 2.7
Migraine (self-reported) 0.3 0.4 0.9 0.3 0.9 0.3 -0.2 0.8 0.7 0.7 0.7 0.6 0.9 0.7 0.7 0.8 0.6 0.4 0.7 0.7 0.8 -0.8 0.7 -0.7 -0.8 -0.7 0.8 -0.6 -0.0 0.2 -0.2 0.2 0.2 -0.6 0.8 -0.8 -0.9 -0.7 -0.9 -0.3 -0.7
Medication: Ibuprofen 1.0 1.2 3.4 -0.1 -1.8 -1.0 -1.3 1.1 0.8 0.2 1.2 0.4 0.7 0.6 0.3 -0.0 -0.7 -0.4 0.3 0.9 1.1 -1.0 1.0 -1.2 -1.6 -1.3 -1.1 -1.2 -1.3 0.2 -1.7 -0.8 -0.3 -1.6 1.2 -1.3 -1.1 -1.4 -1.2 -1.7 -1.4
Medication: Allopurinol 0.3 0.4 3.8 0.7 0.5 0.0 1.2 0.1 -0.1 0.6 0.3 0.1 0.4 0.2 0.3 0.5 -0.2 1.2 0.4 0.5 0.0 0.3 0.3 0.1 0.0 0.0 1.2 0.1 -0.3 0.0 1.0 2.0 1.5 0.8 -0.3 0.3 0.1 0.4 0.5 1.1 0.3
Medication: Omeprazole 1.7 2.0 4.2 -2.1 -0.1 -0.7 0.7 -1.6 -1.6 -1.6 -1.6 -1.3 -1.7 -1.6 -1.3 -1.4 0.1 -1.5 -1.3 -1.7 -1.6 0.4 -1.7 1.7 1.6 2.0 -1.1 1.6 1.5 -1.7 0.9 -0.5 -0.6 1.2 -1.6 1.5 1.6 1.5 1.6 0.8 1.5
Medication: Seretide 50 evohaler 1.7 1.9 4.7 -1.0 -1.7 -0.7 -0.0 -1.5 -1.4 -1.1 -1.9 -2.2 -1.3 -1.7 -1.9 -2.1 -1.6 -2.1 -1.8 -1.5 -1.5 0.6 -1.7 1.2 1.6 1.2 -1.0 1.1 1.0 -0.8 1.2 -1.0 -0.7 1.4 -1.5 1.3 1.1 1.4 1.1 1.1 1.3
Mean time to correctly identify matches 0.6 1.2 4.8 -1.9 0.6 -0.7 0.2 -1.2 -1.1 -0.4 -0.9 -1.0 -0.5 -0.7 -0.7 0.0 -0.7 -0.7 -1.0 -0.7 -1.1 0.4 -1.0 1.1 0.8 0.8 0.6 0.7 -0.1 -2.0 1.9 1.4 0.2 2.1 -1.2 1.3 0.9 1.5 1.1 2.2 1.3
Heart disease (mother) 1.0 1.2 2.4 -0.9 0.7 0.1 0.0 -1.4 -1.1 -1.2 -1.6 -0.7 -1.3 -1.1 -0.8 -1.1 -0.4 -1.4 -1.3 -1.3 -1.1 1.2 -1.3 1.1 1.4 1.2 -0.7 1.2 1.6 -0.7 0.6 -1.5 -0.5 0.4 -1.3 1.0 1.5 1.1 0.9 0.4 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 1.5 -0.6 -0.2 -1.2 -0.2 -0.6 -0.5 -0.6 -0.3 -1.1 -0.7 -0.8 -1.0 -0.4 -0.4 -0.4 -0.5 -0.7 -0.7 -0.5 -0.6 0.6 0.4 0.2 -0.3 0.4 -0.3 -1.0 0.6 0.3 -0.6 0.8 -0.4 0.6 0.2 0.6 0.5 0.6 0.6
Whole body fat mass 2.5 10.3 18.5 -3.0 1.3 -2.6 2.9 -3.6 -3.6 -3.9 -3.5 -1.7 -3.8 -3.2 -2.7 -2.3 -2.7 -1.5 -3.3 -3.9 -3.8 4.3 -3.3 3.7 3.8 4.2 -1.6 4.1 4.2 -3.3 2.8 -0.5 -1.6 3.1 -3.5 3.6 3.2 3.5 3.6 2.2 3.5
Leg fat mass (right) 3.0 11.5 19.8 -3.3 1.5 -2.5 3.3 -3.9 -3.8 -4.1 -3.9 -1.9 -4.0 -3.4 -2.9 -2.4 -2.5 -1.6 -3.5 -4.1 -4.1 4.2 -3.6 3.9 4.0 4.4 -1.7 4.3 4.4 -3.5 3.0 -0.6 -1.6 3.4 -3.7 3.8 3.5 3.7 3.8 2.4 3.8
Arm predicted mass (right) 1.6 8.0 22.6 3.4 3.5 1.4 0.1 3.2 3.1 2.4 3.5 4.4 2.7 3.4 3.5 4.1 2.6 4.8 3.6 2.8 2.8 0.0 3.7 -2.7 -2.7 -2.1 2.3 -2.1 -0.7 2.5 -2.4 0.7 1.3 -2.2 3.3 -2.7 -3.5 -3.0 -2.5 -1.6 -3.0
Pulse rate, automated reading 0.2 0.6 2.4 -0.7 -0.1 1.2 -0.6 0.6 0.9 1.0 0.7 0.9 0.7 0.9 0.8 1.3 0.4 0.3 0.6 0.8 0.8 -1.1 0.8 -0.9 -0.7 -1.3 0.7 -0.9 -1.6 -0.1 -0.5 0.1 0.4 -0.2 0.7 -0.6 -1.0 -0.6 -0.7 0.1 -0.7
Alcohol intake frequency. 3.5 8.1 14.7 -3.8 -0.1 -3.6 1.5 -3.2 -3.3 -3.6 -3.2 -3.7 -3.0 -3.4 -3.4 -2.9 -2.1 -2.7 -3.2 -3.0 -3.1 1.9 -3.1 3.1 2.5 3.1 -2.2 2.7 2.5 -3.2 2.1 -0.8 -1.0 2.6 -3.2 2.9 3.1 2.9 3.1 1.9 2.9
Comparative height size at age 10 0.6 3.5 6.8 1.9 -0.1 -0.7 -0.6 2.4 1.9 1.2 2.6 2.4 2.0 2.2 1.9 2.1 1.1 2.3 2.2 2.1 2.0 -0.4 2.5 -2.0 -2.6 -2.2 0.7 -1.9 -1.4 1.1 -1.9 0.4 1.2 -2.1 2.3 -2.1 -2.2 -2.3 -1.9 -1.7 -2.2
Number of full sisters 1.0 1.2 5.1 -1.8 -2.0 -2.3 0.3 -0.6 -1.0 -0.8 -0.4 -1.6 -0.4 -1.1 -1.5 -1.7 -2.1 -1.4 -1.4 -0.4 -0.5 0.4 -0.8 0.7 0.5 0.9 -1.8 0.5 0.7 -1.7 0.4 0.3 -0.3 0.5 -0.8 0.7 0.8 0.6 0.8 0.1 0.6
Suffer from ‘nerves’ 0.1 0.2 1.8 0.4 0.9 1.1 -0.0 -0.0 -0.1 0.7 -0.0 -0.3 0.4 0.1 0.1 0.2 0.5 -0.1 -0.1 0.2 0.3 -0.6 -0.3 0.0 0.3 0.4 1.0 0.0 0.3 -0.3 0.6 0.4 1.4 -0.3 0.0 0.1 0.6 0.2 -0.1 0.5 0.2
Overall health rating 2.6 5.7 10.5 -2.5 -1.2 -2.9 0.8 -2.4 -2.9 -2.5 -2.4 -3.0 -2.5 -2.8 -2.8 -2.9 -2.5 -2.2 -2.9 -2.3 -2.6 1.7 -2.7 2.5 2.2 2.7 -1.9 2.2 1.4 -3.2 2.3 -0.1 0.2 2.1 -2.5 2.4 2.7 2.6 2.5 1.9 2.6
Chest pain or discomfort 0.8 1.2 3.4 -1.2 0.4 -0.4 -0.4 -1.1 -1.2 -1.3 -1.6 -1.2 -1.1 -1.1 -1.1 -1.5 -0.3 -1.4 -1.3 -1.3 -1.0 0.7 -1.3 1.0 1.0 1.7 -1.0 1.2 1.8 -0.9 0.4 -1.4 -1.6 0.3 -1.0 0.7 1.1 0.8 0.6 -0.3 0.9
Had major operations 1.9 2.3 4.0 -0.6 -0.0 -1.7 1.1 -1.7 -1.8 -1.6 -1.3 -1.4 -1.7 -1.7 -1.5 -1.2 -1.2 -1.0 -1.4 -1.7 -1.9 1.5 -1.8 1.9 1.5 1.8 -0.3 1.8 1.3 -1.4 2.0 1.1 -0.4 1.6 -1.5 2.0 1.5 1.8 1.8 1.3 1.8
Age at last live birth 1.4 2.0 3.6 1.7 -0.3 1.6 -0.9 1.6 1.6 1.6 1.4 1.5 1.5 1.6 1.4 1.3 1.0 1.4 1.6 1.6 1.6 -1.2 1.7 -1.4 -1.4 -1.6 0.7 -1.7 -1.8 1.9 -1.1 0.3 0.4 -1.2 1.3 -1.5 -1.6 -1.5 -1.3 -1.2 -1.5
Family relationship satisfaction 0.9 1.1 2.8 -0.8 0.2 -1.6 0.3 -1.2 -1.1 -0.6 -0.8 -1.2 -0.8 -1.1 -1.0 -0.4 -1.1 -1.2 -1.2 -1.0 -1.1 0.5 -1.2 1.0 0.9 1.0 0.4 0.9 0.6 -1.2 1.7 0.8 -0.2 1.2 -1.0 1.3 1.1 1.3 0.9 1.3 1.3
Leg pain on walking 2.7 3.4 11.3 -2.2 0.4 -1.8 1.8 -1.8 -1.9 -1.4 -1.4 -1.5 -1.7 -1.9 -1.6 -1.4 -1.7 -1.2 -1.8 -1.7 -1.9 2.7 -1.9 1.8 2.1 2.8 -0.5 2.5 3.4 -2.1 1.7 0.8 0.2 1.8 -1.5 1.9 1.9 1.9 1.8 1.8 1.9
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.4 3.9 0.2 -1.5 -2.0 -1.8 1.5 0.9 1.2 1.9 -0.3 1.5 0.8 0.3 0.5 -0.6 0.1 0.6 1.4 1.2 -1.1 1.1 -1.3 -1.9 -1.3 0.3 -1.4 -1.8 -0.3 -0.8 1.0 0.5 -0.9 1.8 -1.1 -1.6 -1.3 -1.4 -0.3 -1.3
Commuting to job workplace: Car/motor vehicle 0.1 0.2 1.2 -0.6 -0.3 0.3 0.0 0.2 0.1 -0.1 -0.1 0.4 -0.1 0.1 0.2 -0.8 0.4 -0.5 0.0 -0.0 0.2 -0.8 -0.1 -0.2 -0.1 0.2 -1.1 -0.0 0.2 0.1 -0.7 -1.1 -0.1 -0.2 0.1 -0.5 -0.3 -0.3 -0.3 -0.3 -0.4
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 2.1 1.0 1.1 1.1 -0.2 0.2 0.8 0.5 0.0 1.0 0.4 0.7 0.9 0.4 1.5 0.6 0.6 0.2 0.4 -0.9 0.4 -0.5 -0.1 -0.4 0.3 -0.2 -0.0 0.9 -0.6 -0.7 -0.3 -0.4 0.1 -0.5 -0.2 -0.4 -0.5 -0.4 -0.4
Medication: Aspirin 3.6 4.8 7.0 -2.4 -0.5 -1.8 0.6 -2.5 -2.7 -2.3 -2.6 -2.6 -2.3 -2.6 -2.5 -2.3 -2.2 -2.5 -2.6 -2.5 -2.6 0.8 -2.5 2.3 2.2 2.4 -1.4 2.2 1.4 -2.6 2.3 -0.5 -1.2 2.1 -2.4 2.4 2.3 2.4 2.2 1.5 2.5
Supplements: Vitamin C 1.4 1.7 5.2 0.7 -1.8 -0.3 -1.8 1.3 0.9 0.3 0.7 0.4 0.8 0.6 0.4 -0.7 0.4 -0.4 0.6 0.8 1.2 -2.1 0.9 -1.4 -1.5 -1.3 -1.5 -1.5 -1.6 1.0 -1.9 -1.6 -1.2 -1.8 1.3 -1.5 -1.5 -1.7 -1.4 -2.3 -1.6
Knee pain experienced in last month 2.2 3.4 6.9 -2.6 0.1 -1.5 1.0 -2.1 -2.0 -1.8 -2.0 -1.9 -1.7 -1.9 -1.9 -0.8 -1.8 -1.4 -2.0 -1.9 -2.1 1.8 -1.9 2.0 2.1 2.2 -0.4 2.0 1.7 -2.3 2.1 0.0 0.1 2.1 -2.1 2.2 2.1 2.2 2.0 2.0 2.2
Hypertension (Self-reported) 4.3 12.0 40.3 -4.5 -4.8 -3.3 -0.8 -3.0 -3.8 -4.1 -3.8 -4.4 -3.8 -4.1 -4.2 -6.3 -3.6 -5.3 -4.2 -3.7 -3.0 0.6 -3.7 3.0 2.6 3.4 -5.7 2.4 2.0 -3.3 0.5 -4.1 -2.6 0.8 -3.1 2.1 3.1 2.2 2.5 -0.4 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.2 0.8 0.2 -0.7 0.8 -0.6 0.2 0.2 0.1 0.4 0.4 -0.0 0.3 0.4 0.5 0.9 0.6 0.6 -0.0 0.0 -0.3 0.3 -0.2 -0.1 -0.4 0.4 -0.3 -0.9 0.1 -0.3 -0.1 0.1 -0.3 0.4 -0.1 -0.2 -0.3 -0.1 -0.3 -0.2
Illnesses of father: Heart disease 4.6 6.4 11.7 -2.1 -0.9 -1.3 0.6 -3.0 -3.0 -2.3 -3.2 -3.2 -2.6 -3.0 -2.9 -3.2 -2.1 -3.4 -3.1 -2.9 -2.8 1.0 -3.4 2.8 2.9 2.6 -1.4 2.5 2.0 -1.8 2.6 -0.5 -1.7 2.4 -2.9 2.7 2.9 2.9 2.4 1.8 2.9
Illnesses of siblings: Diabetes 0.3 0.4 1.7 -0.3 0.7 -0.4 1.1 -0.2 -0.6 -0.4 -0.2 0.2 -0.1 -0.2 0.1 0.1 0.4 0.5 0.2 -0.1 -0.6 1.0 -0.1 0.6 0.3 0.1 0.6 0.3 0.2 -0.3 1.2 1.2 1.3 1.0 -0.5 0.6 0.3 0.7 0.7 1.2 0.6
Smoking status: Previous 0.3 0.5 1.5 -0.3 -1.2 0.1 -1.0 0.7 0.6 0.6 0.6 0.2 0.7 0.6 0.0 0.4 -0.5 0.2 0.3 0.6 0.7 -1.2 0.7 -0.7 -0.6 -0.8 -0.6 -1.0 -1.1 -0.1 -0.9 -0.3 -1.1 -0.4 0.7 -0.7 -1.2 -0.9 -0.7 -0.9 -0.8
Forced expiratory volume in 1-second (FEV1), predicted 1.9 3.9 9.6 1.8 -0.0 0.0 -0.4 2.5 2.2 1.9 3.1 2.3 2.1 2.0 2.1 1.7 1.5 1.8 2.4 2.5 2.3 -0.3 2.5 -2.2 -2.5 -1.5 1.0 -1.9 -0.7 1.8 -1.9 0.9 2.0 -2.0 2.7 -2.2 -2.5 -2.4 -2.0 -1.2 -2.4
Whole body fat-free mass 1.6 8.9 24.4 3.7 2.8 1.5 -0.1 3.4 3.4 2.5 3.7 4.3 2.8 3.5 3.4 4.1 2.5 4.9 3.8 3.0 3.0 -0.1 3.9 -2.9 -2.9 -2.3 2.2 -2.2 -0.8 2.7 -2.8 0.7 1.1 -2.5 3.6 -2.9 -3.8 -3.3 -2.8 -2.0 -3.3
Leg fat-free mass (right) 1.1 6.1 19.0 3.5 2.5 1.6 0.3 2.7 2.8 2.1 3.1 3.6 2.2 2.8 2.9 3.4 2.1 4.4 3.1 2.3 2.4 0.3 3.1 -2.2 -2.1 -1.7 2.0 -1.6 -0.4 2.5 -2.2 0.7 1.3 -2.1 2.9 -2.3 -2.9 -2.6 -2.1 -1.6 -2.6
Arm fat percentage (left) 4.9 19.4 29.4 -4.2 0.4 -2.8 2.7 -5.3 -4.9 -5.0 -5.2 -3.7 -5.2 -4.8 -4.3 -3.9 -3.7 -3.3 -4.9 -5.4 -5.2 4.5 -5.1 5.0 5.4 5.3 -2.4 5.2 4.7 -4.5 3.9 -1.0 -2.5 4.2 -5.0 4.9 4.9 4.9 4.8 3.0 5.0
Average weekly red wine intake 1.6 2.4 8.2 2.1 1.4 2.9 -1.3 1.4 1.7 1.4 1.4 2.1 1.5 1.8 1.9 2.2 1.4 0.9 1.8 1.2 1.5 -0.2 1.5 -1.6 -1.1 -1.2 1.5 -1.1 -0.5 2.1 -1.4 -0.5 -0.8 -1.7 1.5 -1.4 -1.4 -1.6 -1.7 -1.6 -1.5
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.6 0.3 0.4 -0.8 0.1 -0.1 -0.3 -0.2 0.1 0.1 -0.1 -0.1 -0.2 -0.5 -0.4 -0.4 -0.3 -0.1 -0.1 -0.2 -0.3 0.2 -0.1 0.5 -0.7 0.2 0.3 -0.5 0.2 0.2 -0.5 -0.1 -0.1 0.1 0.2 0.1 0.1 -0.2 0.1
Mood swings 0.1 0.2 0.7 -0.2 -0.7 -0.3 0.5 -0.1 -0.6 -0.2 -0.0 -0.6 -0.4 -0.5 -0.6 -0.6 -0.3 -0.4 -0.4 -0.2 -0.2 0.1 -0.5 0.5 0.3 0.3 -0.4 0.2 -0.2 -0.5 0.6 0.7 0.9 0.1 -0.2 0.4 0.3 0.3 0.5 0.2 0.4
Loneliness, isolation 0.1 0.1 1.3 0.1 0.0 -0.7 -1.1 -0.0 0.1 0.3 0.1 -0.6 0.1 -0.3 -0.3 -0.2 -0.0 -0.6 -0.5 -0.0 0.2 -0.9 -0.3 -0.2 -0.0 -0.1 0.2 -0.3 -0.2 -0.2 -0.1 -0.2 -0.3 -0.3 0.3 -0.1 -0.0 -0.1 -0.5 0.2 -0.1
Long-standing illness, disability or infirmity 3.7 5.6 9.7 -3.0 -1.6 -0.9 0.5 -2.6 -2.9 -2.4 -3.0 -2.9 -2.6 -2.9 -2.6 -3.1 -1.4 -2.8 -2.7 -2.6 -2.6 0.8 -3.0 2.5 2.5 2.8 -1.7 2.1 0.9 -2.5 2.2 -0.9 0.1 1.7 -2.8 2.5 3.0 2.6 2.6 1.4 2.7
Ever had bowel cancer screening 0.1 0.1 1.3 -0.4 0.3 -0.0 -0.8 -0.3 -0.0 -0.5 -0.3 0.2 -0.2 0.1 -0.0 0.7 0.2 0.3 -0.0 -0.3 -0.1 -0.4 0.1 -0.1 -0.1 -0.2 -0.1 0.1 -0.8 -0.4 -0.3 -0.7 -1.1 0.3 -0.0 0.1 -0.4 -0.0 0.0 -0.2 -0.0
Diabetes diagnosed by doctor 3.8 6.3 13.0 -3.6 -1.4 -3.6 -0.1 -2.6 -3.1 -3.1 -2.9 -2.9 -2.4 -2.6 -2.8 -2.7 -2.6 -2.9 -3.0 -2.6 -2.8 1.1 -2.7 2.5 1.8 2.6 -2.2 1.9 0.8 -3.6 2.3 -0.6 -1.6 2.5 -2.8 2.4 2.2 2.6 2.4 1.6 2.6
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 3.6 -1.9 -1.1 -0.4 0.5 -1.3 -1.4 -1.6 -1.6 -1.7 -1.8 -1.7 -1.7 -1.8 -1.0 -1.3 -1.5 -1.6 -1.3 0.5 -1.5 1.5 1.7 1.0 -1.7 1.3 0.9 -1.2 0.4 -1.3 -0.6 0.7 -1.4 1.2 1.2 1.1 1.4 0.2 1.1
Friendships satisfaction 2.1 2.6 5.9 -1.6 0.3 -0.7 1.3 -1.9 -1.9 -0.9 -1.6 -2.0 -1.6 -1.9 -1.8 -0.9 -1.4 -1.5 -1.7 -1.5 -1.9 0.7 -1.9 1.8 1.9 1.4 0.3 1.5 0.8 -1.9 2.4 1.1 0.4 2.0 -1.7 2.0 1.9 2.1 1.7 2.1 2.1
Qualifications: nursing, teaching 0.5 0.7 2.5 1.6 1.6 1.2 -0.2 0.6 0.8 0.4 0.7 1.3 0.4 0.9 1.2 1.6 1.1 1.5 1.1 0.5 0.4 0.2 0.9 -0.5 -0.6 -0.5 1.4 -0.4 -0.3 0.8 -0.2 0.2 0.4 -0.5 0.7 -0.5 -0.6 -0.5 -0.6 -0.2 -0.5
Commuting to job workplace: Walk 0.3 0.3 2.3 0.8 1.1 1.0 -1.0 -0.1 0.3 0.8 0.1 -0.4 0.5 0.3 0.1 1.3 -0.4 0.4 0.0 0.2 0.2 0.1 0.1 -0.0 0.1 -0.3 1.5 -0.4 -0.6 0.1 0.7 0.9 -0.2 0.3 0.3 0.2 0.0 0.2 -0.3 0.7 0.2
Eye problems/disorders: Cataract 0.1 0.1 0.5 0.1 0.2 0.2 -0.4 -0.5 -0.1 -0.2 -0.6 -0.0 -0.1 -0.2 -0.0 -0.0 -0.1 -0.1 -0.4 -0.4 -0.4 0.2 -0.4 0.4 0.5 0.6 0.4 0.3 0.7 0.3 0.2 -0.4 -0.7 0.3 -0.6 0.3 0.6 0.4 0.2 0.1 0.4
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 3.2 0.6 1.4 1.7 -0.0 0.6 0.5 1.1 0.7 0.7 0.7 0.7 0.8 1.4 0.2 0.8 0.9 0.9 0.7 0.1 0.7 -0.7 -0.5 -0.5 1.8 -0.5 -0.9 0.6 0.5 0.9 1.4 0.2 0.4 -0.3 -0.7 -0.2 -0.5 1.0 -0.3
Medication for cholesterol 2.7 4.1 11.2 2.3 1.9 1.5 0.1 2.0 2.3 2.2 2.4 2.6 2.1 2.5 2.6 3.3 2.1 2.8 2.5 2.3 2.1 -0.5 2.4 -2.2 -2.1 -1.7 2.6 -1.6 -1.3 2.0 -1.1 1.9 1.1 -1.0 2.2 -1.8 -2.1 -1.8 -1.8 -0.4 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 8.5 10.0 16.4 -4.0 -0.5 -3.0 1.9 -3.6 -3.9 -3.9 -3.5 -3.4 -3.6 -3.5 -3.4 -3.3 -2.7 -2.9 -3.5 -3.4 -3.6 2.5 -3.6 3.5 2.9 3.8 -2.7 3.3 2.4 -3.7 2.4 -0.8 -0.8 2.9 -3.7 3.3 3.5 3.3 3.6 2.0 3.3
Back pain experienced in last month 0.9 1.2 5.2 -1.6 -0.6 -0.5 -0.6 -1.0 -0.9 -1.2 -1.2 -1.1 -1.2 -1.1 -1.5 -1.0 -1.5 -1.3 -1.5 -1.4 -0.9 0.0 -1.1 1.1 1.2 1.3 -1.6 0.8 1.2 -1.4 -0.0 -1.7 -2.3 0.3 -0.7 0.8 0.5 0.6 0.6 -0.4 0.7
Mineral and other dietary supplements 0.6 0.9 2.2 0.2 0.6 0.0 0.9 -1.1 -0.9 -0.6 -0.9 -1.2 -1.3 -1.2 -1.0 -0.9 -0.4 -0.1 -0.9 -1.0 -1.0 0.6 -1.1 1.2 1.4 0.8 -0.2 1.0 0.6 -0.5 1.1 0.3 0.3 0.8 -1.1 1.1 1.5 1.2 1.2 0.8 1.2
Breast cancer (self-reported) 0.3 0.3 2.4 1.0 0.9 1.5 0.1 -0.1 0.3 0.3 0.2 0.5 0.0 0.3 0.5 0.3 1.4 0.5 0.5 0.0 0.1 0.2 0.1 -0.2 0.1 0.2 0.4 0.2 0.3 1.4 -0.6 0.0 0.2 -0.7 0.2 0.0 0.4 -0.2 0.0 -0.5 -0.1
Asthma (self-reported) 6.5 13.0 22.6 -3.3 -2.9 -2.6 1.3 -3.9 -4.1 -3.9 -4.3 -4.8 -4.1 -4.4 -4.6 -4.7 -4.4 -4.6 -4.4 -4.1 -3.8 2.1 -4.2 3.7 3.8 3.2 -3.4 3.4 2.3 -3.1 2.7 -1.8 -2.0 2.7 -3.9 3.5 3.8 3.5 3.5 1.6 3.6
Osteoporosis (self-reported) 0.3 0.4 1.8 -0.1 -0.1 0.8 0.3 -0.7 -0.8 -0.3 -0.9 -0.3 -0.6 -0.6 -0.4 -1.3 0.5 -0.8 -0.5 -0.6 -0.6 -0.6 -1.0 0.5 0.7 1.1 -0.5 0.4 0.1 0.1 0.6 -0.4 0.3 0.3 -0.7 0.6 1.0 0.6 0.6 0.3 0.7
Osteoarthritis (self-reported) 2.1 2.7 5.3 -1.9 0.5 -1.7 1.3 -1.8 -1.8 -1.6 -1.7 -1.6 -1.6 -1.7 -1.7 -1.1 -1.9 -1.5 -1.9 -1.6 -1.8 1.6 -1.7 1.7 1.6 1.8 -0.7 1.7 1.2 -2.1 1.9 -0.1 0.3 2.2 -1.8 1.7 1.4 2.0 1.6 2.3 1.8
Medication: Aspirin 3.0 4.0 6.0 -2.1 -0.4 -1.7 0.6 -2.3 -2.5 -2.0 -2.4 -2.3 -2.0 -2.3 -2.2 -2.2 -1.9 -2.3 -2.4 -2.2 -2.4 0.6 -2.3 2.1 2.0 2.3 -1.2 2.0 1.4 -2.4 2.2 -0.3 -0.9 2.0 -2.2 2.2 2.2 2.3 2.0 1.5 2.3
Medication: Gliclazide 1.8 2.0 9.4 -2.1 -0.8 -3.1 -0.1 -1.2 -1.8 -1.9 -1.3 -2.0 -1.3 -1.5 -1.7 -1.1 -1.4 -1.4 -1.3 -1.4 -1.7 0.2 -1.3 1.5 0.4 1.6 -0.8 0.9 -0.4 -2.4 1.6 0.4 -0.6 1.7 -1.3 1.4 0.8 1.4 1.3 1.2 1.4
Illnesses of father: None of the above (group 1) 4.3 5.3 9.1 2.0 1.5 1.5 -0.6 2.6 2.7 2.4 2.9 2.9 2.5 2.8 2.7 3.0 2.2 2.8 2.9 2.7 2.5 -0.7 2.9 -2.6 -2.7 -2.1 1.7 -2.0 -1.4 1.8 -2.1 1.0 1.8 -2.2 2.8 -2.3 -2.4 -2.5 -2.2 -1.2 -2.5
Smoking status: Current 0.3 0.5 4.0 -0.6 -1.6 -2.0 -1.0 0.1 -0.3 -0.7 0.1 -1.2 -0.1 -0.4 -0.9 -0.8 -1.9 -0.8 -0.7 -0.2 -0.1 0.1 -0.1 0.1 -0.4 -0.3 -1.4 -0.2 -0.4 -0.6 -0.5 -0.8 -0.2 -0.4 0.2 -0.2 -0.2 -0.2 -0.1 -0.4 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.6 3.4 7.5 -1.7 0.3 -0.6 1.6 -2.0 -2.2 -2.0 -2.1 -1.6 -2.1 -2.1 -1.6 -2.1 -0.9 -1.2 -1.8 -2.0 -2.1 2.2 -2.1 2.2 2.0 2.7 -0.9 2.2 2.7 -1.8 1.6 -0.1 0.0 1.2 -2.0 2.0 2.7 2.0 2.1 1.0 2.1
Whole body water mass 1.5 8.7 23.1 3.6 2.7 1.6 -0.1 3.4 3.4 2.5 3.7 4.3 2.8 3.4 3.4 4.0 2.5 4.8 3.7 2.9 3.0 -0.2 3.8 -2.9 -2.8 -2.3 2.0 -2.2 -0.8 2.7 -2.9 0.6 1.0 -2.6 3.6 -2.9 -3.7 -3.3 -2.7 -2.1 -3.3
Leg predicted mass (right) 1.1 5.9 18.7 3.5 2.5 1.6 0.2 2.7 2.8 2.0 3.0 3.6 2.2 2.8 2.8 3.4 2.0 4.3 3.1 2.3 2.3 0.3 3.1 -2.2 -2.0 -1.7 1.9 -1.6 -0.4 2.5 -2.2 0.6 1.2 -2.1 2.9 -2.3 -2.9 -2.6 -2.1 -1.6 -2.5
Arm fat mass (left) 2.3 9.4 16.4 -2.6 1.3 -2.2 2.3 -3.6 -3.4 -3.7 -3.5 -1.9 -3.7 -3.2 -2.7 -2.2 -2.5 -1.5 -3.2 -3.9 -3.7 3.8 -3.3 3.6 3.8 4.0 -1.4 3.9 3.9 -3.1 2.6 -0.7 -2.0 2.9 -3.3 3.5 3.2 3.4 3.3 2.0 3.4
Number of self-reported non-cancer illnesses 3.4 5.9 14.1 -2.8 -2.4 -1.9 0.4 -2.4 -3.0 -2.7 -2.8 -3.1 -2.6 -2.9 -2.9 -3.8 -2.8 -3.4 -2.9 -2.7 -2.5 0.5 -2.9 2.4 2.2 2.6 -2.8 2.0 1.2 -2.6 1.6 -1.8 -0.6 1.5 -2.6 2.2 2.5 2.3 2.2 1.2 2.3
Average weekly champagne plus white wine intake 0.6 0.8 3.4 1.5 0.7 1.8 -0.8 0.6 1.1 1.5 0.8 0.8 0.8 1.0 1.0 1.6 0.9 1.1 0.8 0.7 0.8 -0.8 1.0 -0.6 -0.2 -0.8 1.5 -1.0 -1.2 0.3 0.1 0.9 0.5 -0.1 0.7 -0.5 -0.7 -0.4 -0.7 0.4 -0.5
Miserableness 0.1 0.1 0.5 0.0 0.0 0.6 -0.7 -0.2 -0.3 0.2 -0.2 -0.5 -0.3 -0.5 -0.3 -0.5 -0.0 -0.6 -0.2 -0.3 -0.1 -0.0 -0.5 0.2 0.4 0.5 0.1 0.2 -0.1 -0.1 0.4 0.1 0.0 0.1 0.1 0.3 -0.0 0.2 0.1 0.3 0.2
Guilty feelings 0.1 0.1 0.6 -0.3 0.0 -0.6 -0.6 -0.2 -0.4 -0.5 -0.2 -0.1 -0.4 -0.3 -0.1 -0.1 0.1 -0.3 -0.2 -0.3 -0.4 0.1 -0.3 0.3 0.1 0.1 -0.2 -0.0 -0.4 -0.8 0.2 0.1 -0.4 0.0 -0.1 0.3 0.3 0.2 0.2 -0.1 0.3
Wears glasses or contact lenses 0.4 0.4 3.1 -0.2 -0.0 1.2 -0.9 -0.4 -0.4 -0.3 -0.9 -0.4 -0.5 -0.3 -0.4 -0.6 -0.3 -0.7 -0.5 -0.6 -0.3 -1.2 -0.4 0.3 0.5 0.8 -0.9 0.2 -0.4 -0.3 -0.2 -1.1 -1.8 -0.3 -0.5 0.1 0.5 0.1 0.2 -1.0 0.2
Ever taken oral contraceptive pill 1.3 1.4 2.6 1.4 -1.3 -0.2 -1.2 1.4 1.3 1.2 1.4 0.3 1.2 0.9 0.6 -0.1 0.1 0.4 0.8 1.4 1.5 -1.4 1.2 -1.6 -1.6 -1.2 -0.4 -1.2 -1.3 1.2 -1.6 -0.1 0.2 -1.4 1.5 -1.5 -1.4 -1.5 -1.4 -1.2 -1.5
Hearing aid user 2.3 2.6 4.8 -1.2 -0.3 -2.2 0.8 -1.7 -1.9 -1.7 -1.7 -1.8 -1.3 -1.8 -1.8 -1.3 -1.5 -1.5 -1.8 -1.7 -1.8 1.0 -1.9 1.8 1.4 2.1 -0.4 1.6 1.6 -2.0 2.0 0.3 -0.4 1.8 -1.7 1.8 1.6 1.9 1.5 1.6 1.8
Mother’s age at death 1.1 1.4 7.2 1.2 1.6 2.7 -0.3 0.9 1.2 0.6 0.4 1.6 0.6 1.2 1.2 1.3 1.9 1.2 1.3 0.6 1.0 -0.7 0.9 -1.1 -0.5 -0.9 0.6 -0.7 -0.1 1.8 -1.5 -1.7 -0.4 -1.5 0.7 -1.2 -0.7 -1.1 -1.0 -1.6 -1.1
Financial situation satisfaction 2.3 2.8 6.5 -1.7 0.5 -1.6 1.9 -1.8 -1.8 -1.4 -1.5 -1.5 -1.6 -1.6 -1.6 -0.5 -0.9 -0.9 -1.4 -1.5 -1.9 1.5 -1.7 1.9 1.8 1.8 0.5 1.8 1.6 -1.8 2.5 1.1 1.0 2.0 -1.8 2.1 1.9 2.1 2.0 2.2 2.2
Tinnitus: Yes, now most or all of the time 1.2 1.4 4.4 -1.0 -0.9 -0.3 -0.5 -1.4 -1.4 -0.8 -1.3 -2.1 -1.1 -1.5 -1.5 -1.5 -0.9 -1.7 -1.5 -1.4 -1.2 0.5 -1.6 1.2 1.4 1.4 -0.4 1.1 0.9 -1.0 1.1 -0.2 -0.5 1.0 -1.1 1.2 1.4 1.3 1.0 1.1 1.3
Commuting to job workplace: Public transport 3.9 4.7 7.2 -1.8 -0.5 -1.2 1.3 -2.5 -2.6 -2.3 -2.3 -2.4 -2.5 -2.6 -2.5 -1.7 -2.2 -1.8 -2.4 -2.5 -2.6 1.9 -2.4 2.5 2.5 2.2 -0.8 2.4 1.4 -2.5 2.4 0.3 -0.9 1.9 -2.4 2.6 2.7 2.5 2.5 1.3 2.6
Eye problems/disorders: Glaucoma 0.7 0.9 3.0 0.6 0.2 1.3 -1.3 0.6 1.1 0.9 0.4 0.4 0.9 0.8 0.9 0.2 1.7 0.5 0.8 0.8 1.0 -0.6 0.7 -1.2 -0.7 -0.7 0.4 -0.8 -0.5 1.7 -1.6 -1.2 0.1 -1.1 1.0 -1.0 -0.7 -1.1 -1.1 -0.8 -1.1
Medication: Blood pressure 3.8 7.3 18.6 -3.3 -1.9 -2.0 -0.5 -2.7 -2.9 -3.2 -3.3 -3.6 -2.9 -3.2 -3.5 -4.3 -2.4 -3.8 -3.3 -3.1 -2.6 -0.3 -3.1 2.7 2.5 2.7 -3.9 2.0 2.0 -2.7 0.8 -3.2 -3.1 1.2 -2.6 2.0 2.2 2.0 1.9 -0.1 2.1
Pain type(s) experienced in last month: Hip pain 6.8 8.6 15.4 -3.9 -0.5 -1.8 1.8 -3.4 -3.3 -3.1 -3.1 -3.0 -3.3 -3.3 -3.2 -2.5 -2.7 -2.8 -3.3 -3.4 -3.2 2.4 -3.4 3.3 3.2 3.4 -2.0 3.2 2.7 -3.5 2.5 -0.9 -0.6 2.7 -3.1 3.2 3.2 3.2 3.1 2.4 3.2
Supplements: Fish oil (including cod liver oil) 0.8 1.0 2.2 -0.2 -0.1 0.2 -1.3 1.0 1.0 0.4 0.7 1.2 1.2 1.2 1.1 1.1 0.4 0.0 0.9 0.8 1.0 -0.5 1.0 -1.3 -1.3 -1.4 0.3 -1.1 -0.8 0.9 -1.3 -1.2 -1.0 -0.8 0.9 -1.2 -1.5 -1.2 -1.3 -1.0 -1.2
High cholesterol (Self-reported) 3.7 6.5 12.8 -2.7 -2.1 -3.0 -0.3 -2.9 -2.9 -2.9 -3.1 -3.3 -2.7 -3.0 -3.0 -3.5 -2.5 -3.6 -3.2 -3.0 -2.7 0.3 -3.1 2.7 2.2 2.4 -2.5 2.1 1.3 -2.6 1.8 -1.6 -1.8 1.8 -2.6 2.5 2.5 2.4 2.2 1.2 2.5
Medication: Bendroflumethiazide 1.6 2.4 5.7 -1.8 -1.7 -2.1 -0.5 -1.4 -1.6 -1.9 -1.7 -2.3 -1.6 -1.9 -2.1 -2.4 -1.4 -1.6 -1.7 -1.8 -1.6 -0.5 -1.7 1.6 1.2 1.5 -2.1 0.9 0.0 -2.0 0.5 -1.3 -1.7 0.8 -1.4 1.3 1.1 1.1 1.3 0.0 1.2
Medication: Paracetamol 1.0 1.5 9.0 -2.2 -1.6 -3.0 -0.8 -0.8 -1.0 -1.8 -0.9 -1.7 -1.0 -1.0 -1.6 -1.3 -1.7 -1.4 -1.4 -0.9 -0.8 -0.1 -0.8 0.8 -0.0 0.9 -2.2 0.5 0.2 -2.1 -0.3 -1.1 -1.3 0.2 -0.5 0.5 0.4 0.3 0.6 -0.4 0.4
Medication: Lisinopril 0.5 0.7 3.1 -0.6 -1.7 -1.0 -0.7 -0.3 -0.8 -0.9 -0.7 -1.1 -0.7 -0.8 -0.9 -1.8 -0.4 -1.4 -0.8 -0.6 -0.5 -1.0 -0.6 0.4 -0.0 0.8 -1.5 0.1 -0.3 -0.5 -0.1 -1.2 -0.8 -0.4 -0.6 0.1 0.6 0.2 0.2 -0.8 0.3
Medication: Atorvastatin 4.5 5.5 8.4 -2.2 -0.3 -2.6 1.1 -2.8 -2.8 -2.8 -2.9 -2.2 -2.4 -2.6 -2.2 -2.8 -1.4 -2.8 -2.8 -2.7 -2.8 1.6 -2.8 2.5 2.3 2.8 -1.5 2.5 2.3 -2.2 2.2 -0.5 -1.3 2.5 -2.7 2.5 2.5 2.6 2.4 1.8 2.6
Illnesses of father: High blood pressure 1.4 1.8 5.2 -1.1 -0.8 -1.6 1.3 -1.2 -1.4 -1.4 -1.1 -1.6 -1.4 -1.7 -1.7 -2.0 -1.0 -1.5 -1.4 -1.3 -1.3 1.1 -1.5 1.4 1.5 1.7 -1.3 1.6 2.3 -1.0 0.8 -0.4 -0.1 0.6 -1.2 1.2 1.4 1.1 1.3 0.4 1.2
Alcohol drinker status: Never 3.5 4.2 15.4 -2.7 -0.5 -3.9 -0.4 -2.2 -2.2 -2.9 -2.3 -2.5 -2.1 -2.3 -2.3 -2.4 -1.2 -3.0 -2.6 -2.2 -2.0 0.6 -2.3 1.9 1.0 2.5 -2.1 1.6 2.1 -2.9 0.6 -1.5 -2.3 0.8 -1.7 1.6 2.1 1.5 1.3 0.1 1.6
Ever smoked 2.0 3.5 5.5 1.3 -1.2 2.1 -2.2 2.1 2.1 2.1 2.0 1.3 2.0 1.9 1.4 1.5 0.5 1.3 1.6 1.7 2.2 -2.0 2.1 -2.0 -1.6 -2.3 0.0 -2.2 -2.2 1.5 -2.3 -0.5 -0.9 -2.0 2.2 -2.1 -2.3 -2.3 -2.1 -2.2 -2.2
Basal metabolic rate 0.9 4.9 16.5 2.9 2.6 1.0 0.4 2.4 2.5 1.6 2.8 3.6 1.9 2.5 2.6 3.2 1.8 4.1 2.8 2.0 2.1 0.5 2.9 -2.0 -1.9 -1.4 1.6 -1.3 -0.0 1.9 -2.1 0.5 0.7 -1.8 2.7 -2.0 -2.8 -2.4 -1.9 -1.5 -2.3
Leg fat percentage (left) 6.0 21.6 31.9 -4.7 1.2 -2.9 3.6 -5.5 -5.3 -5.2 -5.5 -3.5 -5.3 -4.9 -4.3 -3.7 -3.5 -3.2 -5.0 -5.5 -5.5 4.9 -5.2 5.4 5.6 5.7 -2.0 5.5 5.3 -4.7 4.6 -0.5 -2.1 4.8 -5.4 5.3 5.1 5.3 5.2 3.6 5.3
Arm fat-free mass (left) 1.0 5.0 15.4 2.7 3.1 1.0 0.2 2.5 2.5 1.7 2.7 3.6 2.1 2.7 2.7 3.4 2.0 3.9 2.8 2.1 2.1 0.3 2.9 -2.0 -2.0 -1.4 1.8 -1.5 -0.0 1.9 -1.9 0.6 0.4 -1.6 2.7 -2.1 -2.9 -2.4 -2.0 -1.4 -2.3
Number of operations (self-reported) 4.2 6.3 12.0 -2.6 0.0 -1.1 1.8 -2.9 -3.0 -2.2 -2.5 -2.2 -2.5 -2.6 -2.3 -1.8 -2.1 -2.0 -2.5 -2.8 -2.8 2.3 -3.0 2.9 2.9 3.5 -0.4 3.0 2.4 -2.7 3.0 1.1 -0.8 3.1 -2.7 3.1 2.4 3.0 3.0 2.7 3.0
Average weekly beer plus cider intake 0.3 0.4 1.3 0.0 -0.4 -0.3 -0.1 0.8 0.5 0.6 0.6 0.2 0.9 0.6 0.3 0.1 -1.2 0.6 0.1 1.0 0.8 0.3 0.8 -0.9 -0.7 -1.0 -0.3 -0.7 0.1 0.6 -0.8 0.3 -0.9 -0.3 0.7 -0.9 -1.0 -0.8 -0.8 -0.7 -0.9
Irritability 0.4 0.7 2.3 1.5 1.4 1.0 0.1 1.0 0.7 0.6 0.9 1.1 0.7 0.7 0.8 1.1 0.7 0.7 1.1 0.8 0.8 -0.1 0.7 -0.7 -0.7 -0.6 0.9 -0.7 0.1 1.2 -0.5 -0.2 0.4 -1.1 0.9 -0.9 -0.8 -0.9 -0.9 -0.9 -0.8
Risk taking 1.4 2.1 3.7 1.7 -0.7 -0.4 -1.7 1.6 1.4 1.4 1.8 1.0 1.7 1.6 1.3 1.5 1.1 0.8 1.5 1.6 1.7 -1.1 1.5 -1.7 -1.9 -1.9 1.0 -1.8 -1.9 1.5 -1.1 0.5 0.8 -1.5 1.8 -1.4 -1.6 -1.6 -1.6 -0.9 -1.5
Ever had prostate specific antigen (PSA) test 3.9 4.5 9.0 1.7 -0.5 0.6 -2.1 2.5 2.4 1.7 2.2 2.3 2.5 2.5 2.4 2.0 1.9 1.4 2.2 2.4 2.5 -1.6 2.7 -2.6 -3.0 -2.1 1.0 -2.3 -1.9 2.0 -2.2 -0.1 0.1 -1.9 2.3 -2.7 -2.7 -2.5 -2.6 -1.8 -2.6
Fractured/broken bones in last 5 years 0.1 0.2 2.4 -0.0 0.3 -1.5 0.1 -0.2 -0.4 -0.7 0.2 -0.2 -0.2 -0.2 -0.4 0.1 -0.6 -0.3 -0.2 -0.2 -0.4 0.1 -0.2 0.2 -0.3 -0.0 -0.3 0.2 0.2 -0.8 0.1 -0.5 0.9 -0.3 -0.0 0.2 0.3 0.1 0.1 0.3 0.2
Age started oral contraceptive pill 0.1 0.2 1.4 0.4 0.4 -0.0 0.5 -0.1 0.0 -0.6 -0.3 0.3 -0.4 -0.1 -0.1 -0.0 0.8 0.2 0.1 -0.3 -0.0 -0.2 -0.0 0.1 0.1 0.2 -0.4 0.3 0.6 -0.0 -0.6 -0.6 -1.2 -0.4 -0.1 -0.1 0.2 -0.2 0.1 -0.9 -0.1
Diastolic blood pressure, automated reading 5.8 18.0 39.3 -6.1 -3.1 -6.2 1.3 -4.2 -4.8 -6.3 -5.3 -4.3 -4.8 -4.7 -4.7 -5.9 -3.0 -5.1 -4.8 -4.7 -4.5 1.9 -4.6 4.2 3.1 4.3 -5.2 3.9 3.9 -4.8 1.7 -3.6 -2.9 2.4 -4.3 3.4 4.0 3.5 3.8 0.6 3.6
Ever depressed for a whole week 0.5 0.7 3.2 -0.9 0.3 -0.1 0.9 -0.6 -0.7 -0.2 -0.2 -0.7 -0.5 -0.7 -0.5 0.1 -0.7 -0.0 -0.4 -0.2 -0.7 1.0 -0.6 0.7 0.6 0.5 0.5 0.6 -0.2 -1.0 1.3 1.5 1.4 1.3 -0.6 1.0 0.6 1.0 1.1 1.8 0.9
Unable to work because of sickness or disability 0.1 0.1 0.9 -0.9 -0.2 -0.7 0.1 -0.3 -0.3 -0.2 -0.2 -0.1 -0.2 -0.3 -0.3 -0.1 -0.5 -0.3 -0.5 -0.1 -0.1 0.7 -0.3 0.2 0.3 0.4 -0.1 0.3 0.3 -0.4 0.3 0.3 -0.2 0.7 -0.1 0.3 -0.2 0.3 0.3 0.6 0.2
Commuting to job workplace: Cycle 3.2 3.9 10.5 2.3 0.2 2.3 -1.4 2.1 2.2 2.5 2.1 1.6 2.3 2.2 2.0 2.4 1.3 1.9 2.0 2.3 2.1 -2.5 2.2 -2.1 -2.0 -2.9 1.7 -2.5 -3.2 1.5 -1.3 0.9 1.2 -1.3 1.9 -1.9 -1.9 -1.8 -1.8 -0.6 -1.9
Myopia 0.8 1.1 5.4 -0.0 -2.3 0.3 -1.3 0.6 0.4 -0.1 0.4 -0.2 0.1 0.1 -0.3 -1.0 -0.6 -0.8 0.1 0.2 0.6 -1.8 0.4 -0.8 -0.9 -0.8 -2.3 -0.9 -1.6 -0.1 -1.8 -1.6 -1.4 -1.5 0.9 -0.9 -0.8 -1.1 -0.7 -2.0 -1.0
Vascular/heart problems diagnosed by doctor 4.5 12.2 36.8 4.3 3.9 3.2 0.8 3.2 4.0 4.3 4.0 4.2 3.9 4.1 4.2 6.1 3.3 5.1 4.2 3.9 3.2 -0.6 3.9 -3.2 -2.9 -3.7 5.4 -2.6 -2.5 3.4 -0.8 4.1 3.0 -0.9 3.2 -2.4 -3.2 -2.4 -2.5 0.4 -2.5
Cholesterol lowering medication 3.3 4.8 8.1 -2.2 -0.8 -1.2 -0.6 -2.5 -2.6 -2.2 -2.6 -2.8 -2.3 -2.5 -2.7 -2.8 -2.1 -2.8 -2.8 -2.7 -2.4 -0.1 -2.7 2.5 2.4 1.8 -2.1 1.8 1.0 -2.7 1.9 -1.4 -2.0 1.9 -2.3 2.3 2.0 2.2 1.9 1.2 2.3
Medication: Omeprazole (e.g. Zanprol) 2.1 2.6 5.7 -2.4 -0.3 -0.5 0.9 -1.9 -1.8 -2.0 -1.9 -1.4 -2.1 -1.8 -1.5 -1.6 -0.2 -1.7 -1.5 -2.0 -1.9 0.7 -1.9 1.9 1.9 2.2 -1.5 1.9 1.6 -1.8 0.9 -0.8 -0.8 1.2 -1.8 1.7 1.8 1.6 1.9 0.6 1.6
Pain experienced in last month 3.1 5.3 12.1 2.6 -0.8 2.2 -1.4 2.6 2.5 2.3 2.5 2.4 2.3 2.5 2.4 1.7 1.8 1.9 2.5 2.4 2.5 -2.1 2.6 -2.5 -2.4 -3.3 0.6 -2.7 -3.5 2.6 -2.3 0.5 0.2 -2.1 2.5 -2.4 -2.5 -2.5 -2.2 -2.0 -2.5
Supplements: Calcium 0.7 0.8 2.6 1.1 -0.2 -0.0 -1.0 1.0 0.9 1.1 0.7 0.5 1.2 1.0 0.9 0.3 0.9 0.4 0.6 1.1 0.9 -1.2 0.9 -1.1 -1.1 -0.9 0.4 -1.3 -1.6 0.5 -0.4 0.3 1.2 -0.8 0.7 -0.9 -0.6 -0.8 -0.9 -0.2 -0.8
Basal cell carcinoma (self-reported) 0.2 0.2 1.9 -0.6 1.2 -0.3 -0.5 -0.3 -0.0 0.2 -0.1 -0.1 0.1 0.0 -0.1 0.5 -0.9 0.3 -0.4 -0.1 -0.1 0.3 -0.1 -0.1 0.4 0.5 0.5 0.2 0.8 -0.8 0.2 0.3 -1.4 0.6 -0.0 0.2 -0.2 0.2 -0.1 0.1 0.1
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.7 -0.7 -0.4 -0.3 -1.2 -0.4 -0.5 -0.5 -0.5 -0.7 -0.4 -0.5 -0.6 -0.5 -0.2 -1.3 -0.7 -0.7 -0.4 -0.5 -0.6 0.3 0.2 0.0 -0.4 0.0 -0.2 -0.5 0.2 -1.2 -0.9 0.0 -0.4 0.2 0.2 0.3 -0.0 0.0 0.3
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 5.0 -0.3 -1.7 -1.8 0.1 -0.9 -1.4 -0.9 -0.9 -1.6 -0.9 -1.2 -1.3 -2.2 -1.0 -1.3 -1.5 -0.9 -1.0 -0.1 -1.2 0.9 0.7 1.0 -1.4 0.5 0.3 -1.4 1.0 0.3 -0.0 0.5 -0.9 0.9 1.1 0.9 0.8 0.4 1.0
Heart disease (siblings) 4.9 6.1 10.0 -2.7 -2.0 -0.8 1.5 -2.8 -2.7 -2.4 -3.0 -2.9 -2.8 -3.0 -2.8 -2.9 -2.4 -3.0 -2.8 -2.8 -2.5 1.7 -3.0 2.8 3.2 2.3 -2.0 2.7 2.3 -1.6 1.9 -0.8 -1.3 1.8 -2.8 2.5 3.0 2.5 2.7 1.0 2.6
Alcohol drinker status: Previous 0.5 0.6 4.6 0.7 0.9 0.7 0.8 0.0 0.0 0.7 0.4 -0.1 0.3 0.1 0.3 0.9 0.5 0.8 0.6 0.5 -0.0 0.6 0.2 0.1 0.1 -0.2 1.6 -0.1 -0.8 0.5 1.0 1.9 2.1 0.7 -0.2 0.4 0.3 0.4 0.5 1.3 0.4
Pack years of smoking 3.1 4.6 10.7 -2.9 0.3 -2.2 2.1 -2.4 -2.1 -2.7 -2.1 -1.8 -2.5 -2.2 -2.1 -1.5 -2.1 -1.4 -2.2 -2.5 -2.4 2.9 -2.2 2.4 2.3 2.6 -1.6 2.7 3.3 -2.0 1.1 -1.0 -0.6 2.2 -2.1 2.1 1.8 2.1 2.3 1.8 2.0
Impedance of whole body 0.5 2.4 9.9 -2.4 -2.8 -2.5 -0.1 -1.4 -1.8 -1.5 -1.3 -2.2 -1.3 -1.7 -1.8 -2.3 -2.2 -3.1 -1.8 -1.1 -1.4 0.5 -1.7 1.2 0.7 0.6 -1.6 0.9 0.1 -1.6 1.3 -0.0 -0.0 0.9 -1.5 1.3 1.5 1.4 1.2 0.7 1.4
Leg fat mass (left) 2.7 10.6 19.1 -3.0 1.7 -2.2 3.1 -3.8 -3.6 -3.8 -3.7 -1.8 -3.8 -3.2 -2.7 -2.1 -2.3 -1.4 -3.2 -3.9 -3.9 4.2 -3.4 3.8 4.0 4.3 -1.3 4.1 4.4 -3.2 3.0 -0.4 -1.4 3.3 -3.6 3.7 3.4 3.6 3.7 2.4 3.7
Arm predicted mass (left) 0.8 4.2 13.7 2.4 2.8 0.5 0.4 2.3 2.2 1.4 2.6 3.4 1.9 2.4 2.4 3.1 1.7 3.7 2.6 1.9 1.9 0.5 2.7 -1.8 -1.9 -1.1 1.5 -1.2 0.2 1.6 -1.9 0.5 0.4 -1.5 2.5 -1.9 -2.8 -2.2 -1.8 -1.4 -2.2