Best TWAS P=6.42e-10 · Best GWAS P=3.31e-12 conditioned to 2.11e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | C17orf103 | 0.08 | 0.01 | enet | 11 | 0.04 | 6.6e-04 | -4.1 | -5.5 | 4.6e-08 | 0.43 | 0.16 | 0.46 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | C17orf103 | 0.11 | 0.02 | enet | 15 | 0.07 | 1.0e-06 | -2.6 | -5.8 | 5.1e-09 | 0.30 | 0.38 | 0.08 | FALSE |
| 3 | GTEx | Thyroid | DHRS7B | 0.17 | 0.02 | enet | 22 | 0.11 | 1.2e-08 | 3.5 | 6.2 | 6.4e-10 | -0.17 | 0.84 | 0.02 | TRUE |
| 4 | GTEx | Thyroid | KCNJ12 | 0.36 | 0.23 | lasso | 5 | 0.25 | 2.9e-19 | 5.1 | 5.7 | 1.4e-08 | -0.48 | 0.99 | 0.01 | FALSE |