Best TWAS P=6.68e-08 · Best GWAS P=8.5e-17 conditioned to 1.55e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DHRS13 | 0.04 | 0.01 | blup | 304 | 0.02 | 6.0e-04 | 2.4 | -5.2 | 1.8e-07 | 0.02 | 0.32 | 0.02 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | ANKRD13B | 0.14 | 0.09 | enet | 8 | 0.11 | 1.2e-05 | -4.9 | -5.4 | 6.7e-08 | 0.25 | 0.39 | 0.16 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ABHD15 | 0.04 | 0.03 | lasso | 2 | 0.02 | 1.4e-05 | -4.9 | -5.2 | 1.9e-07 | 0.23 | 0.47 | 0.01 | FALSE |