Hub : Genes

AFAP1-AS1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.329	0.101	1.7e-03	0.165	NA	0.073	NA	0.162	5.2e-05	NA	6.2e-03	NA	5.9e-05
2	GTEx	Brain Cerebellum	0.466	0.111	4.3e-04	0.054	NA	0.012	NA	0.099	1.1e-02	NA	1.4e-01	NA	7.6e-04
3	GTEx	Cells Transformed fibroblasts	0.197	0.050	4.8e-05	0.087	NA	0.072	NA	0.071	4.7e-07	NA	4.7e-06	NA	5.4e-06
4	GTEx	Esophagus Mucosa	0.361	0.058	6.2e-12	0.275	NA	0.283	NA	0.294	1.4e-18	NA	3.6e-19	NA	5.9e-20
5	GTEx	Skin Not Sun Exposed Suprapubic	0.334	0.064	2.2e-08	0.295	NA	0.278	NA	0.287	1.4e-16	NA	1.5e-15	NA	4.0e-16
6	GTEx	Skin Sun Exposed Lower leg	0.341	0.052	2.3e-14	0.261	NA	0.198	NA	0.240	1.2e-21	NA	3.1e-16	NA	8.3e-20
7	GTEx	Testis	0.343	0.086	3.3e-04	-0.005	NA	0.009	NA	0.021	6.6e-01	NA	1.2e-01	NA	4.0e-02
8	GTEx	Whole Blood	0.360	0.045	0.0e+00	0.327	NA	0.321	NA	0.331	7.8e-31	NA	2.9e-30	NA	2.6e-31

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.9	1.5	4.7	1.6	2.2	-0.9	0.6	0.8	0.7	-1.2	0.8
Bipolar Disorder or Schizophrenia	0.4	0.9	5.2	1.1	2.3	-0.2	-0.1	0.1	-0.2	-0.8	0.0
Depressed Affect (Nagel 2018)	1.5	3.2	8.3	-2.9	-2.0	1.5	-1.7	-1.7	-1.4	0.6	-1.6
Depression (Nagel 2018)	0.6	0.9	1.6	-1.3	-0.9	0.6	-1.0	-1.0	-1.1	0.4	-1.1
Intelligence (Savage-Jansen 2018)	1.9	5.7	9.8	2.5	1.2	-0.6	3.1	2.9	3.0	1.2	3.0
Neuroticism (Nagel 2018)	2.1	4.8	7.3	-2.7	-2.1	1.6	-2.5	-2.4	-2.4	0.4	-2.4
Schizophrenia (2018)	0.2	0.4	1.7	0.1	1.3	0.5	-0.5	-0.5	-0.7	0.0	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.6	1.6	0.8	0.7	-0.8	0.7	0.4	0.6	-1.3	0.5
Worry (Nagel 2018)	1.0	2.1	3.6	-1.5	-0.8	1.1	-1.7	-1.8	-1.9	0.8	-1.6
Alzheimer’s Disease (in mother)	0.4	0.4	1.4	0.8	1.0	-1.2	0.4	0.2	0.2	-0.1	0.4
Alzheimer’s Disease (in father)	1.2	1.3	2.2	-1.0	-0.5	1.2	-1.2	-1.1	-1.4	1.5	-1.2
Alzheimer’s Disease (including proxy)	0.2	0.2	0.5	0.1	0.6	-0.7	-0.3	-0.5	-0.6	0.5	-0.4
Crohns Disease (2017)	0.5	1.1	3.7	-1.0	-1.9	1.2	-0.0	-0.4	-0.2	1.5	-0.3
Irritable Bowel Disease (IBD)	0.6	1.3	2.9	-1.7	-1.4	1.6	-0.1	-0.4	-0.3	1.7	-0.4
Ulcerative Colitis (UC)	0.7	1.3	3.8	-2.0	-0.9	1.2	-0.7	-0.8	-0.8	1.2	-0.9
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.2	0.5	1.4	-0.9	0.1	0.8	-0.4	-0.6	-0.4	-1.2	-0.3
Verbal and Numeric Reasoning (VNR)	1.4	3.5	6.9	1.1	0.6	1.0	2.6	2.2	2.6	1.2	2.3
Breast Cancer	0.7	1.7	3.2	1.8	0.2	-0.9	1.4	1.6	1.5	0.1	1.7
Ovarian Cancer	0.2	0.2	1.1	-0.2	1.0	-0.5	-0.0	0.0	0.1	-0.7	-0.2
Prostate Cancer	0.7	1.0	3.5	0.8	-0.3	0.0	1.3	0.7	1.0	1.9	1.0
Age at First Birth	0.7	1.1	2.0	1.2	1.3	-1.3	0.7	0.8	0.5	-1.4	0.6
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.7	0.9	1.4	-1.1	-0.4	-0.9	-1.1	-1.1	-1.0	-0.8	-1.2
Coronary Artery Disease (CAD)	1.6	1.9	3.0	-1.6	0.1	1.7	-1.5	-1.7	-1.4	-0.8	-1.4
Crohns Disease (2012)	1.6	2.6	5.4	1.2	0.3	0.2	2.3	1.9	2.0	1.7	2.0
Mean Putamen Volume	1.2	1.3	2.8	-0.8	-1.7	0.9	-1.3	-1.2	-1.2	-0.7	-1.2
Fasting Glucose	0.5	0.6	3.7	0.3	-0.1	0.7	0.4	0.4	0.5	1.9	0.5
HbA1C	2.9	3.2	5.3	-1.3	-1.5	0.6	-2.1	-2.0	-2.0	-2.3	-1.9
HDL Cholesterol	0.3	0.5	1.7	-0.0	1.3	1.2	-0.5	-0.4	-0.5	-0.1	-0.4
LDL Cholesterol	0.1	0.2	0.5	0.5	-0.2	-0.3	0.5	0.3	0.5	0.7	0.4
Lupus	1.4	2.2	4.2	-0.9	-0.8	1.1	-1.5	-1.9	-2.1	1.2	-1.7
Neuroticism (2016)	0.6	0.8	3.6	-1.4	-1.9	0.3	-0.2	-0.0	-0.2	0.8	-0.2
Primary Biliary Cirrhosis	0.6	0.8	1.6	-1.1	-1.3	0.8	-0.6	-1.1	-0.7	0.7	-0.6
Rheumatoid Arthritis	2.5	3.4	5.8	2.0	2.3	-0.4	2.4	1.9	2.0	0.1	2.1
Schizophrenia (2014)	0.3	0.7	2.3	0.7	1.5	-0.3	-0.6	-0.5	-0.5	-1.3	-0.4
Triglycerides	0.4	0.7	1.4	-0.7	-1.0	-1.2	-0.8	-0.8	-0.5	-1.0	-0.8
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	-0.3	-0.7	0.1	0.2	0.2	0.2	0.7	0.0
Ulcerative Colitis	0.7	1.0	2.1	-0.2	-0.3	-0.5	1.4	1.4	1.5	0.6	1.2
Blood Eosinophil Count	0.8	5.9	8.9	-2.7	-1.1	2.5	-2.8	-3.0	-2.9	0.4	-2.8
Blood Platelet Count	0.1	1.1	4.5	0.5	1.3	-1.4	-0.3	-0.0	-0.2	-2.1	-0.2
Blood Red Count	0.1	1.4	6.2	1.4	2.5	-1.4	0.4	0.2	0.3	-0.6	0.4
Blood White Count	0.1	1.0	5.9	-0.1	1.4	-0.5	0.1	-0.1	-0.2	-2.4	-0.0
Heel T-Score	0.3	2.4	6.2	-1.2	-0.6	2.5	-2.1	-1.5	-1.7	0.0	-1.5
BMI	0.9	5.1	8.9	-3.0	-1.8	0.9	-2.6	-2.6	-2.6	0.3	-2.7
Height	2.7	52.9	81.4	9.0	7.8	-6.7	7.4	7.5	7.6	-2.3	7.8
Waist Hip Ratio (WHR)	1.4	6.4	9.8	-3.1	-0.2	3.1	-2.4	-2.8	-3.1	0.8	-2.9
Systolic Blood Pressure	3.8	19.1	34.3	5.9	5.7	-2.6	4.2	4.5	4.4	-1.8	4.4
Smoking Status	1.6	3.8	5.4	2.0	2.3	-1.7	2.1	1.9	2.2	-0.5	2.0
Allergy or Eczema	0.8	2.0	4.5	-1.0	-0.7	0.7	-1.5	-2.0	-2.1	-0.9	-1.7
Cardiovascular Disease	0.9	2.9	4.3	-1.8	-0.1	2.1	-2.0	-1.8	-2.0	-0.7	-2.1
Hypothyroidism (self reported)	0.8	1.8	2.6	-1.6	-1.6	-0.1	-1.1	-1.5	-1.6	-0.9	-1.5
Respiratory disease	2.8	6.3	11.2	-3.3	-3.1	1.4	-2.8	-2.5	-2.5	0.2	-2.6
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.3	-0.4	-0.6	1.5	-0.3	-0.4	-0.5	0.5	-0.4
Lung FEV1/FVC ratio	4.5	22.7	47.6	6.9	3.9	-4.8	4.2	4.7	4.7	-2.8	5.2
Lung FVC	0.7	3.4	6.2	-2.4	-1.2	2.5	-1.9	-1.7	-1.3	1.7	-1.6
Neuroticism	3.8	9.0	15.5	-3.9	-2.2	2.5	-3.3	-3.4	-3.4	1.0	-3.3
Chronotype (morning person)	0.8	1.8	6.8	0.4	2.6	-0.9	0.8	0.6	0.6	-2.3	0.5
Hair Pigment	0.0	0.6	1.2	0.7	1.1	-0.3	0.8	0.9	0.9	-0.6	0.8
Tanning	0.0	0.3	1.9	0.3	-0.5	-1.4	-0.3	-0.1	-0.1	-0.4	-0.0
Hand grip strength (left)	4.0	10.6	21.4	4.6	2.8	-2.3	3.4	3.5	3.5	0.5	3.7
Number of treatments/medications taken	1.7	3.0	6.5	-2.5	-0.6	2.5	-1.6	-1.5	-1.7	1.1	-1.7
Average weekly spirits intake	6.9	8.5	15.3	-3.9	-2.6	2.1	-3.3	-3.0	-3.1	0.9	-3.4
Sensitivity / hurt feelings	0.8	1.3	2.4	-1.0	-0.4	0.8	-1.3	-1.5	-1.5	0.1	-1.5
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.3	-1.0	-0.0	-0.2	-1.0	-1.1	-1.1	-0.1	-1.0
Hearing difficulty/problems: Yes	2.6	3.9	13.7	-3.7	-1.2	1.0	-1.7	-2.0	-1.9	-0.7	-2.1
Relative age of first facial hair	0.1	0.2	0.8	0.9	0.1	0.7	-0.1	-0.1	-0.1	0.5	0.2
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	3.2	-1.8	-1.3	1.2	-1.5	-1.3	-1.2	0.1	-1.3
Ever used hormone-replacement therapy (HRT)	0.8	1.0	2.7	-1.6	-1.6	-0.3	-0.6	-0.6	-0.8	-0.6	-1.0
Ever had hysterectomy (womb removed)	0.4	0.5	1.4	0.6	0.7	-1.2	0.3	0.3	0.2	-1.1	-0.0
Systolic blood pressure, automated reading	1.8	5.3	11.5	3.4	2.9	-1.6	2.2	2.2	2.1	-0.2	2.4
Eye problems/disorders: Diabetes related eye disease	3.4	3.7	6.1	-2.5	-2.1	1.4	-2.0	-2.1	-2.1	0.0	-2.2
Angina	4.3	5.6	12.7	1.7	1.9	-2.9	1.9	2.2	2.3	-3.6	2.1
Medication for hormone replacement therapy	1.4	1.5	2.3	-1.5	-0.6	1.5	-1.1	-1.2	-1.3	1.1	-1.2
Vitamin and mineral supplements	0.5	0.7	1.5	1.2	0.5	-0.7	0.9	0.8	0.9	-0.4	0.9
Supplements: Zinc	0.2	0.2	1.1	-0.0	-0.2	0.4	-0.3	-0.3	-0.2	1.1	-0.6
Medication: Co-codamol	1.9	2.2	4.9	-1.5	-2.2	1.2	-1.5	-1.6	-1.4	0.4	-1.4
Medication: Metformin	0.8	1.1	1.8	-1.3	-1.2	0.6	-1.0	-0.9	-1.4	0.1	-1.2
Diabetes (father)	1.2	1.5	2.7	-1.1	-0.7	1.1	-1.4	-1.7	-1.4	0.9	-1.4
Diabetes (mother)	1.3	1.6	4.1	-2.0	-0.5	1.0	-1.2	-1.5	-1.3	0.1	-1.5
Severe depression (siblings)	4.9	5.5	11.2	3.3	2.0	-1.6	2.6	2.6	2.4	0.5	2.6
Pack years adult smoking proportion	0.5	0.8	1.7	-1.3	-0.8	0.8	-0.7	-0.7	-0.8	-0.6	-0.9
Impedance of leg (right)	0.6	2.9	8.4	2.9	1.3	-1.5	1.5	1.8	1.8	0.1	1.6
Leg fat-free mass (left)	0.1	0.5	2.8	0.1	1.1	-1.7	0.2	0.1	0.1	-0.4	0.4
Trunk fat percentage	1.9	7.6	15.6	-3.9	-2.3	1.2	-2.8	-2.9	-3.1	1.8	-3.1
Hand grip strength (right)	3.4	9.3	18.2	4.3	2.9	-1.3	3.2	3.3	3.3	1.6	3.4
Townsend deprivation index at recruitment	0.7	1.0	2.5	-1.3	-1.2	1.0	-0.5	-0.5	-0.4	-1.6	-0.8
Current tobacco smoking	1.8	3.0	4.9	1.5	1.3	-0.9	2.0	2.0	2.2	-1.2	2.1
Average weekly fortified wine intake	0.4	0.4	0.8	-0.5	-0.8	0.4	-0.7	-0.8	-0.7	-0.9	-0.4
Maternal smoking around birth	0.1	0.2	0.7	-0.2	-0.8	0.6	-0.3	-0.3	-0.4	0.4	-0.3
Fed-up feelings	3.1	5.6	10.0	-3.2	-1.8	2.7	-2.4	-2.4	-2.0	1.6	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	4.0	-2.0	-0.9	1.0	-1.1	-1.1	-1.3	-0.6	-1.3
Relative age voice broke	0.3	0.5	0.9	0.9	-0.3	0.9	0.7	0.6	0.7	0.3	0.8
Taking other prescription medications	1.5	2.4	3.8	-1.9	-2.0	1.2	-1.5	-1.5	-1.6	0.4	-1.7
Age when periods started (menarche)	0.1	0.3	1.1	0.4	-1.0	0.0	0.1	-0.1	-0.3	0.9	0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.9	0.3	0.3	-0.6	0.3	0.2	0.2	-1.7	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.4	-0.4	0.2	-0.2	-0.7	-0.4	-0.4	1.2	-0.5
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.8	-0.9	-0.3	-0.0	-1.3	-1.5	-1.2	-1.7	-1.3
Qualifications: CSEs or equivalent	1.0	1.3	2.2	-0.4	-0.0	0.9	-1.3	-1.3	-1.3	1.5	-1.3
Serious illness, injury or assault to yourself	0.5	0.7	3.3	-0.3	-0.3	-1.8	0.1	0.0	0.0	-1.4	-0.1
High blood pressure	1.2	3.4	5.5	-2.4	0.5	1.6	-2.1	-1.9	-2.1	-0.9	-2.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.5	-0.2	-0.4	1.3	-1.0	-1.6	-1.5	0.2	-1.0
Multivitamins +/- minerals	0.2	0.2	1.1	0.6	-0.2	-0.1	0.3	0.3	0.3	1.1	0.4
Stomach or abdominal pain in last month	0.4	0.5	1.0	-0.9	0.2	0.3	-1.0	-0.8	-0.8	-0.3	-1.0
Supplements: Glucosamine	0.3	0.4	1.3	0.6	0.8	-1.1	0.4	0.5	0.4	-0.5	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.3	-0.5	0.0	1.1	-0.5	-0.6	-0.3	-0.1	-0.6
Medication: Atenolol	0.8	1.0	2.3	0.7	0.5	0.2	1.1	1.5	1.4	-0.8	1.0
Medication: Levothyroxine sodium	0.5	0.8	1.7	-1.3	-1.3	0.2	-0.7	-0.8	-1.0	-0.2	-1.0
Sitting height	3.2	22.6	32.3	5.7	4.3	-5.5	4.6	4.9	5.1	-1.1	5.2
Chronic bronchitis/emphysema (father)	0.2	0.2	0.9	0.1	0.6	-0.1	0.2	0.3	0.5	-0.9	0.2
High blood pressure (mother)	0.1	0.2	0.6	0.6	0.8	-0.0	0.1	0.5	0.1	-0.5	0.3
Body mass index (BMI)	2.3	9.8	19.4	-4.4	-3.0	1.3	-3.4	-3.4	-3.5	0.5	-3.6
Impedance of leg (left)	0.4	1.9	5.6	2.4	1.3	-0.6	1.2	1.5	1.4	0.2	1.3
Leg predicted mass (left)	0.1	0.5	2.7	0.0	1.0	-1.6	0.2	0.1	0.1	-0.3	0.4
Trunk fat mass	0.8	3.6	8.2	-2.9	-1.3	0.4	-2.0	-2.0	-2.2	1.0	-2.2
Waist circumference	1.3	4.8	10.6	-3.3	-1.6	0.8	-2.3	-2.5	-2.6	-0.0	-2.6
Number of incorrect matches in round	0.1	0.1	0.3	-0.2	0.3	-0.4	-0.0	-0.1	0.1	-0.6	-0.5
Past tobacco smoking	1.3	2.4	5.9	-1.5	-2.4	1.8	-1.5	-1.1	-1.3	-1.0	-1.3
Alcohol usually taken with meals	0.7	1.1	1.7	1.1	1.0	-0.9	1.0	1.1	1.0	-1.3	0.9
Nervous feelings	0.1	0.2	0.4	0.0	0.6	0.5	-0.3	-0.6	-0.5	0.5	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.3	-1.5	-0.4	0.4	-1.2	-1.2	-1.4	-0.7	-1.3
Hearing difficulty/problems with background noise	1.1	1.8	3.9	-1.9	-0.9	-1.0	-0.9	-1.3	-1.1	-2.0	-1.2
Hair/balding pattern: Pattern 2	1.0	1.2	1.9	-0.7	-0.3	1.4	-1.1	-1.3	-1.4	1.1	-1.0
Had menopause	0.6	0.7	1.2	-1.1	-1.0	0.6	-0.7	-0.9	-1.1	-0.1	-1.0
Had other major operations	0.7	0.8	4.4	-0.5	-1.0	-1.0	0.1	-0.1	-0.1	-2.1	-0.0
Forced vital capacity (FVC)	0.8	3.2	7.7	2.8	1.9	-1.5	1.4	1.6	1.9	-0.1	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	4.9	-0.7	-0.5	0.4	-1.0	-0.7	-0.9	2.2	-0.9
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	1.5	-0.8	-1.2	1.2	-0.4	-0.7	-0.5	1.1	-0.7
Qualifications: None of the above	1.2	2.6	8.0	-2.8	-1.4	1.8	-1.3	-1.2	-1.3	-0.1	-1.6
Financial difficulties in last 2 years	0.4	0.5	1.0	1.0	0.7	-0.1	0.7	0.8	0.9	-0.3	0.9
Mouth/teeth dental problems	3.4	5.2	8.3	2.9	2.6	-2.3	1.8	2.2	2.3	-1.6	2.1
Heart attack	2.6	3.4	11.1	1.8	1.6	-0.8	1.4	1.7	1.5	-3.3	1.6
Allergy	1.0	2.3	3.9	1.4	1.3	-1.4	1.6	2.0	1.9	0.1	1.6
Pain all over the body in last month	2.5	2.7	4.9	-2.2	-2.1	1.5	-1.2	-1.3	-1.3	1.9	-1.3
Diabetes (self-reported)	0.4	0.6	1.2	-0.9	-1.1	0.7	-0.6	-0.7	-1.0	0.2	-0.7
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	5.4	2.3	1.3	-1.4	1.4	1.2	1.2	-1.9	1.6
Medication: Ramipril	1.3	1.7	3.1	-1.8	1.0	1.1	-1.6	-1.1	-1.4	-0.0	-1.5
Medication: Simvastatin	0.7	1.0	5.3	-0.0	0.9	-0.9	-0.7	-0.3	-0.4	-2.3	-0.5
Fluid intelligence score	1.6	3.3	5.8	1.7	1.0	0.9	2.4	2.0	2.3	0.7	2.4
Illnesses of siblings	0.9	1.3	4.7	1.1	-0.1	0.6	1.0	0.8	1.0	2.2	1.1
Neuroticism score	3.7	7.8	14.3	-3.8	-1.4	2.3	-3.0	-3.3	-3.2	0.9	-3.2
Weight	0.1	0.6	1.5	-1.1	-0.0	-1.2	-0.7	-0.7	-0.8	-0.4	-0.7
Impedance of arm (right)	0.2	1.2	3.1	-0.5	-0.3	0.7	-1.0	-1.3	-1.2	1.8	-1.1
Arm fat percentage (right)	3.4	13.3	23.8	-4.9	-3.3	1.8	-3.9	-4.1	-4.1	1.4	-4.2
Trunk fat-free mass	1.3	7.4	11.6	2.8	2.8	-3.4	2.4	2.5	2.5	-2.3	2.8
Hip circumference	0.2	1.0	1.8	-1.4	-0.6	-1.0	-1.0	-1.0	-1.1	-0.3	-1.1
Time employed in main current job	0.1	0.1	0.3	0.3	0.1	0.0	-0.1	-0.2	-0.1	-0.5	-0.3
Alcohol intake versus 10 years previously	0.1	0.1	0.5	-0.7	0.1	-0.1	-0.0	0.1	-0.0	-0.5	-0.1
Father’s age at death	0.8	1.1	1.8	1.1	-1.0	-0.4	1.1	0.9	0.9	1.4	1.3
Worrier / anxious feelings	1.0	1.9	5.2	-1.2	-1.5	0.9	-1.0	-1.3	-1.3	2.3	-1.1
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.3	5.4	-2.3	-1.3	2.2	-1.8	-1.9	-2.1	0.3	-1.8
Falls in the last year	1.5	2.1	4.0	-1.7	-2.0	-0.1	-1.4	-1.3	-1.7	-1.2	-1.3
Hair/balding pattern: Pattern 3	2.2	3.2	4.9	2.2	1.5	-1.2	2.0	2.2	2.2	-0.1	1.9
Number of live births	1.2	1.7	2.6	-1.2	-1.6	1.0	-1.1	-1.5	-1.2	1.2	-1.4
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	12.0	3.5	1.7	-1.9	1.6	1.9	2.2	-0.5	2.5
Pulse rate	0.3	0.6	1.8	-0.3	-0.8	1.3	-0.2	-0.1	-0.4	-1.3	-0.2
Happiness	0.8	0.9	6.1	0.9	0.3	-0.3	0.5	-0.0	0.1	2.5	0.4
Noisy workplace	1.9	2.4	5.1	-2.3	-0.2	2.3	-1.5	-1.2	-1.5	0.3	-1.7
Qualifications: A levels/AS levels or equivalent	0.8	1.7	4.9	2.2	1.4	-1.1	1.1	1.0	1.1	0.5	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.3	0.5	1.1	-0.4	0.2	-0.0	-0.2	0.2	0.1
Mouth/teeth dental problems: Dentures	1.5	2.6	8.1	-2.3	-2.8	1.3	-0.9	-1.2	-1.4	-0.6	-1.1
Asthma	2.4	4.6	9.6	-3.1	-2.7	1.0	-2.3	-2.2	-2.0	-0.5	-2.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	5.1	-0.6	-0.7	0.3	-0.2	0.1	-0.1	2.3	-0.3
Medication: Cholesterol lowering	1.3	2.0	5.2	1.1	1.6	-2.0	0.9	1.0	0.9	-2.3	0.8
Depression (self-reported)	1.0	1.1	2.4	-1.0	-0.7	1.6	-0.9	-1.1	-1.3	0.2	-1.2
Medication: Lansoprazole	3.7	4.2	6.2	-2.5	-1.7	1.6	-2.3	-2.2	-2.3	-0.9	-2.4
Prospective memory result	2.3	2.8	4.7	-2.2	-1.2	0.6	-1.9	-2.1	-1.9	0.2	-2.0
Lung cancer (father)	0.5	0.6	2.9	-0.2	1.3	-0.4	0.1	0.2	0.0	-1.7	0.0
Illnesses of mother	0.6	0.7	1.8	-0.3	-1.2	0.9	-0.5	-0.7	-0.7	1.3	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.4	12.7	3.6	1.5	-2.3	2.1	2.2	2.6	-0.1	2.7
Pulse wave Arterial Stiffness index	1.7	2.0	3.6	1.1	0.8	-1.2	1.4	1.4	1.5	-1.9	1.6
Impedance of arm (left)	0.4	1.8	7.5	-0.4	-0.3	1.3	-1.0	-1.2	-1.2	2.7	-1.1
Arm fat mass (right)	1.5	6.3	11.7	-3.4	-2.2	0.7	-2.8	-2.8	-2.9	0.6	-2.9
Trunk predicted mass	1.4	7.9	12.3	2.9	2.9	-3.5	2.5	2.7	2.6	-2.3	2.9
Standing height	3.0	30.0	45.0	6.7	6.2	-5.4	5.4	5.5	5.5	-1.8	5.9
Length of working week for main job	1.1	1.2	1.9	-1.4	0.6	1.0	-1.4	-1.0	-1.1	-0.3	-1.3
Exposure to tobacco smoke at home	0.5	0.6	1.5	0.4	-0.1	-0.2	0.8	1.0	1.0	-1.2	0.7
Breastfed as a baby	5.3	6.5	10.9	2.9	2.0	-2.2	3.3	2.8	2.6	0.7	2.9
Tense / ‘highly strung’	1.0	1.6	3.9	-2.0	-0.0	1.2	-1.2	-1.2	-1.3	-1.2	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.4	-1.2	-0.7	1.2	0.1	-0.0	-0.3	-0.3	-0.4
Hair/balding pattern: Pattern 4	0.1	0.3	0.8	-0.7	-0.7	-0.7	0.2	0.0	0.3	-0.9	-0.0
Birth weight of first child	0.4	0.8	4.6	0.4	-0.7	-1.0	0.3	0.2	0.0	2.1	0.2
Peak expiratory flow (PEF)	0.2	0.6	2.1	1.4	0.2	-1.2	0.4	0.4	0.5	-0.0	0.6
Pulse wave reflection index	1.8	2.2	7.8	1.1	0.9	-2.8	1.0	1.2	1.2	-1.4	1.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.1	-1.4	-0.4	1.4	-1.0	-1.0	-1.0	1.2	-1.1
Loud music exposure frequency	0.2	0.2	1.2	0.3	0.2	-1.1	-0.3	0.0	-0.1	-0.3	0.1
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	4.7	2.2	1.0	-0.6	0.8	0.6	0.8	2.0	1.1
Mouth/teeth dental problems: Bleeding gums	2.5	3.2	5.9	-1.6	-0.3	0.9	-2.2	-2.4	-2.4	0.9	-2.2
Blood clot in the leg (DVT)	2.7	3.5	6.4	-2.5	-1.4	2.1	-1.7	-1.9	-1.7	0.9	-2.1
Medication: Paracetamol	0.5	0.8	2.3	-1.2	-0.5	1.5	-0.7	-0.8	-0.7	0.2	-0.7
Headache pain in last month	0.4	0.7	3.0	0.1	1.7	0.4	0.2	-0.2	-0.4	1.5	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.6	0.8	-0.5	0.1	0.7	0.3	0.4	0.5	0.6
Glaucoma (self-reported)	16.3	19.2	33.1	-5.8	-3.3	2.5	-4.6	-5.2	-5.3	0.9	-5.0
Gout (self-reported)	1.3	1.7	3.8	-0.8	-0.3	-0.5	-1.3	-1.6	-1.6	-1.9	-1.5
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	1.8	-1.1	-1.1	-0.2	-0.7	-0.9	-1.1	-1.4	-1.0
Medication: Amlodipine	0.7	0.9	1.7	-1.3	-0.6	0.5	-1.1	-1.0	-1.2	0.4	-1.2
Medication: Ventolin 100micrograms inhaler	3.8	4.9	8.5	-2.7	-2.3	2.9	-1.9	-1.8	-1.9	1.8	-1.9
Birth weight	0.5	1.1	2.5	1.1	1.1	0.2	1.0	0.7	1.0	1.6	1.1
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.3	-1.4	-1.3	0.1	-1.4	-1.3	-1.2	-0.4	-1.5
High blood pressure (siblings)	0.8	1.2	6.8	0.6	0.6	-1.4	-0.2	-0.1	-0.4	-2.6	-0.2
Forced vital capacity (FVC), Best measure	0.7	2.4	5.2	2.3	1.1	-1.4	1.4	1.6	1.9	0.0	1.9
Body fat percentage	2.1	8.2	15.9	-4.0	-2.4	1.1	-3.1	-3.1	-3.2	1.4	-3.4
Leg fat percentage (right)	1.5	5.4	9.7	-3.1	-2.2	0.3	-2.6	-2.6	-2.7	-0.1	-2.8
Arm fat-free mass (right)	0.8	4.1	6.5	2.1	2.2	-2.5	1.8	2.0	1.9	-1.4	2.1
Exposure to tobacco smoke outside home	0.2	0.2	0.7	-0.8	-0.2	0.2	-0.6	-0.4	-0.4	0.1	-0.7
Comparative body size at age 10	0.3	0.8	2.9	-0.4	0.7	-0.3	-0.6	-0.9	-0.9	-1.7	-0.7
Number of full brothers	0.5	0.6	2.8	0.3	-1.7	-0.6	0.2	0.2	0.5	-1.0	0.2
Worry too long after embarrassment	2.3	3.8	7.4	-2.2	-2.7	2.2	-1.7	-1.8	-1.7	1.2	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.4	-0.6	0.1	0.4	-0.1	-0.1	-0.3	0.4	-0.5
Wheeze or whistling in the chest in last year	2.3	4.1	9.9	-3.1	-1.5	1.7	-2.1	-1.9	-2.1	-0.3	-2.3
Number of children fathered	0.9	1.0	3.0	1.3	1.7	-1.2	0.6	0.7	0.6	-0.0	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.6	-0.3	-0.1	0.4	-0.2	-0.4	-0.3	0.8	-0.4
Age at first live birth	3.6	6.4	10.6	3.2	0.6	-1.9	3.1	2.9	2.9	-0.7	3.0
Pulse wave peak to peak time	1.0	1.2	3.5	-0.7	-0.3	1.0	-1.0	-1.0	-1.0	1.9	-1.2
Health satisfaction	0.9	1.2	2.3	-1.5	-1.3	0.1	-0.7	-0.9	-1.0	1.5	-1.1
Shortness of breath walking on level ground	4.0	4.7	10.2	-3.2	-1.3	1.6	-2.3	-2.4	-2.4	-0.8	-2.4
Qualifications: College or University degree	0.9	2.7	5.5	2.3	1.1	-1.2	1.9	1.7	1.7	-0.8	1.8
Eye problems/disorders: None of the above	11.2	13.0	16.6	4.1	4.1	-3.4	3.9	3.9	3.9	0.5	3.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.1	0.7	0.8	-1.4	0.5	0.4	0.5	0.7	0.4
Emphysema/chronic bronchitis	1.8	2.0	3.2	-1.6	-0.4	-0.4	-1.8	-1.5	-1.5	-1.7	-1.7
Medication for pain relief, constipation, heartburn	0.5	0.9	2.4	1.2	0.8	-1.5	0.6	0.4	0.6	-1.2	0.6
Neck or shoulder pain in last month	0.3	0.5	0.8	-0.9	0.2	0.8	-0.7	-0.7	-0.8	0.5	-0.8
Medication: Blood pressure	0.4	0.7	2.1	-1.5	0.4	0.7	-1.0	-0.7	-0.7	-0.3	-0.9
Angina (self-reported)	3.6	4.8	12.5	1.4	1.7	-2.6	1.7	1.9	2.0	-3.5	1.8
Migraine (self-reported)	2.3	2.9	5.4	-2.3	-1.0	2.2	-1.4	-1.7	-1.7	0.3	-1.8
Medication: Ibuprofen	0.6	0.8	5.6	-0.2	-0.5	0.4	0.1	0.2	-0.1	2.4	0.1
Medication: Allopurinol	0.7	1.0	2.8	-0.3	-0.1	-0.9	-0.9	-1.0	-1.1	-1.7	-1.0
Medication: Omeprazole	0.3	0.4	0.6	0.6	-0.2	0.0	0.7	0.8	0.8	0.5	0.7
Medication: Seretide 50 evohaler	0.4	0.5	0.7	-0.9	-0.8	0.2	-0.8	-0.8	-0.6	-0.2	-0.9
Mean time to correctly identify matches	0.2	0.4	1.6	-0.7	0.0	0.6	-0.3	-0.5	-0.4	-1.3	-0.3
Heart disease (mother)	4.7	5.7	9.9	2.1	1.9	-3.1	2.5	2.6	2.4	-2.1	2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	3.1	1.2	0.5	-1.8	1.8	1.6	1.4	-1.6	1.6
Whole body fat mass	0.9	3.8	8.2	-2.9	-1.4	0.4	-2.1	-2.2	-2.3	0.9	-2.3
Leg fat mass (right)	0.8	3.0	6.4	-2.5	-1.4	-0.2	-1.9	-1.9	-2.0	0.1	-2.1
Arm predicted mass (right)	0.9	4.7	6.6	2.2	2.4	-2.6	2.0	2.2	2.1	-1.4	2.3
Pulse rate, automated reading	0.1	0.3	1.1	-0.2	-0.8	1.0	0.3	0.2	0.1	-0.8	0.2
Alcohol intake frequency.	0.6	1.4	2.4	-0.9	-0.8	0.6	-1.1	-1.2	-1.6	1.6	-1.2
Comparative height size at age 10	1.1	5.9	11.4	2.4	3.2	-3.4	1.8	2.0	2.0	-2.2	2.0
Number of full sisters	1.7	2.1	6.6	-1.7	-1.2	1.6	-1.0	-0.9	-0.8	2.6	-1.0
Suffer from ‘nerves’	0.3	0.4	0.8	-0.6	0.6	0.3	-0.8	-0.8	-0.9	0.1	-0.7
Overall health rating	0.8	1.6	3.4	-1.9	-0.1	1.3	-1.1	-1.4	-1.5	-0.1	-1.6
Chest pain or discomfort	0.3	0.4	2.5	-0.1	0.2	-0.9	-0.1	-0.1	-0.1	-1.6	-0.0
Had major operations	1.4	1.6	3.1	-1.7	-0.2	0.7	-1.3	-1.4	-1.3	-1.6	-1.3
Age at last live birth	8.2	11.9	16.8	4.1	1.3	-4.1	3.8	3.5	3.7	-2.4	3.8
Family relationship satisfaction	2.7	3.3	5.3	1.9	2.2	-2.0	2.3	1.6	1.8	0.4	1.7
Leg pain on walking	3.3	4.1	6.1	2.5	2.4	-1.8	2.1	2.2	2.0	-0.6	2.0
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.1	-0.1	-0.0	0.1	0.2	0.1	0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.5	0.4	0.5	0.3	0.7	0.7	0.5	0.2	0.5
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.0	-0.9	-1.3	1.7	-0.9	-0.8	-0.7	0.9	-0.8
Medication: Aspirin	0.5	0.7	2.6	0.4	1.0	-0.9	0.3	0.7	0.5	-1.6	0.4
Supplements: Vitamin C	2.4	2.8	4.1	-2.0	-1.7	1.6	-1.7	-1.7	-1.8	-0.9	-1.8
Knee pain experienced in last month	0.3	0.5	1.5	0.9	1.2	-0.8	0.1	-0.2	-0.3	-1.1	-0.1
Hypertension (Self-reported)	1.4	3.9	7.2	-2.7	0.0	1.5	-2.2	-2.1	-2.3	-1.0	-2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	4.1	-1.2	-1.8	1.6	-0.7	-0.9	-0.9	2.0	-0.8
Illnesses of father: Heart disease	2.7	3.7	7.4	2.3	2.0	-2.7	1.7	1.7	1.8	-0.9	1.7
Illnesses of siblings: Diabetes	0.8	1.0	1.9	-1.4	-0.7	0.3	-1.1	-1.0	-1.2	0.4	-1.1
Smoking status: Previous	0.7	1.1	3.6	0.6	1.4	-1.4	0.6	0.2	0.5	1.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.1	10.0	3.2	2.4	-1.9	2.2	2.2	2.1	1.4	2.3
Whole body fat-free mass	0.6	3.6	7.5	1.8	2.1	-2.7	1.6	1.6	1.6	-1.4	1.9
Leg fat-free mass (right)	0.1	0.4	1.5	-0.1	1.1	-1.2	0.0	0.0	-0.1	-0.3	0.3
Arm fat percentage (left)	3.6	14.3	25.2	-5.0	-3.4	2.1	-4.0	-4.2	-4.3	1.6	-4.3
Average weekly red wine intake	0.1	0.2	0.7	0.8	-0.4	-0.5	0.2	0.2	0.2	0.6	0.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.8	-1.3	0.2	0.4	-1.2	-1.3	-1.2	1.0	-1.2
Mood swings	2.0	3.7	7.2	-2.7	-1.0	1.9	-2.1	-2.2	-2.0	-0.2	-2.1
Loneliness, isolation	0.2	0.3	1.3	-1.1	-0.6	0.8	-0.0	-0.2	-0.1	-0.5	-0.3
Long-standing illness, disability or infirmity	1.0	1.5	3.5	-1.9	-0.6	1.5	-1.0	-1.1	-1.2	1.0	-1.2
Ever had bowel cancer screening	1.2	1.5	5.2	-2.3	0.3	0.8	-0.9	-1.2	-1.1	-0.5	-1.4
Diabetes diagnosed by doctor	0.1	0.1	0.5	-0.2	-0.7	0.3	0.4	0.3	0.1	-0.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.7	-0.9	-0.5	-0.3	0.1	-0.1	0.1	-1.3	-0.2
Friendships satisfaction	1.0	1.3	4.0	1.4	1.6	-0.0	1.1	0.5	0.5	2.0	0.5
Qualifications: nursing, teaching	0.1	0.2	0.5	0.5	0.3	0.1	-0.1	0.4	0.2	-0.7	0.5
Commuting to job workplace: Walk	0.9	1.0	1.7	-0.8	-0.6	0.6	-1.2	-1.3	-1.3	-0.9	-1.0
Eye problems/disorders: Cataract	1.0	1.1	3.7	-0.7	-1.1	1.9	-1.0	-1.0	-0.9	-0.8	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.2	-0.0	-0.8	0.6	0.3	0.2	0.1	1.5	0.1
Medication for cholesterol	4.9	7.4	11.1	3.2	1.0	-2.4	3.3	3.1	3.3	-0.0	3.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	-0.3	-0.4	-0.7	0.3	0.3	0.3	-0.2	0.1
Back pain experienced in last month	2.2	3.2	9.8	1.9	0.8	-3.1	1.6	1.5	1.4	-1.6	1.5
Mineral and other dietary supplements	0.6	0.8	2.8	-0.6	-1.3	1.1	-0.5	-0.4	-0.4	1.7	-0.5
Breast cancer (self-reported)	0.4	0.5	1.0	-0.5	-0.4	0.7	-1.0	-0.8	-0.9	-0.2	-0.8
Asthma (self-reported)	2.3	4.5	9.1	-3.0	-2.8	0.8	-2.2	-2.2	-2.0	-0.5	-2.1
Osteoporosis (self-reported)	0.3	0.3	0.7	-0.7	0.3	-0.2	0.4	0.7	0.8	0.8	0.2
Osteoarthritis (self-reported)	0.0	0.1	0.2	-0.4	-0.4	-0.0	-0.1	-0.1	0.1	0.3	-0.0
Medication: Aspirin	0.8	1.1	4.0	0.4	0.9	-1.4	0.5	0.8	0.6	-2.0	0.5
Medication: Gliclazide	0.1	0.1	0.4	0.0	-0.1	0.6	0.4	0.4	0.4	-0.0	0.4
Illnesses of father: None of the above (group 1)	1.9	2.3	4.0	-1.7	-1.6	2.0	-1.4	-1.4	-1.6	0.7	-1.5
Smoking status: Current	2.4	3.8	5.7	1.8	1.7	-1.3	2.2	2.2	2.4	-1.4	2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	0.2	-0.1	-0.2	0.0	0.2	0.2	-0.0	0.4
Whole body water mass	0.6	3.3	7.0	1.6	2.1	-2.6	1.5	1.5	1.5	-1.5	1.7
Leg predicted mass (right)	0.1	0.4	1.6	-0.0	1.2	-1.3	0.1	0.1	0.0	-0.3	0.3
Arm fat mass (left)	1.5	6.2	11.9	-3.4	-2.4	0.8	-2.7	-2.7	-2.8	0.8	-2.8
Number of self-reported non-cancer illnesses	0.4	0.8	3.2	-1.8	0.0	0.6	-0.6	-0.7	-0.8	-0.3	-1.1
Average weekly champagne plus white wine intake	0.2	0.3	0.8	-0.3	0.2	0.3	-0.6	-0.9	-0.8	0.1	-0.8
Miserableness	3.7	6.5	9.7	-3.1	-2.7	2.2	-2.7	-2.9	-2.7	-0.5	-2.6
Guilty feelings	0.9	1.3	2.9	-1.7	-0.8	0.9	-1.1	-1.2	-1.2	0.6	-1.3
Wears glasses or contact lenses	1.0	1.2	8.7	0.1	0.3	-0.9	-0.1	-0.0	-0.0	-2.9	0.0
Ever taken oral contraceptive pill	1.9	2.1	6.2	1.1	1.7	-0.7	1.0	1.3	1.4	-2.5	1.1
Hearing aid user	1.3	1.4	3.9	-1.7	-1.2	0.4	-1.0	-0.9	-0.8	-2.0	-0.8
Mother’s age at death	0.4	0.5	2.3	0.2	0.4	-0.8	0.0	-0.5	-0.6	1.5	-0.3
Financial situation satisfaction	0.6	0.7	1.4	1.2	1.0	-0.2	1.0	0.7	0.7	-0.4	0.9
Tinnitus: Yes, now most or all of the time	0.6	0.7	3.0	-1.7	-1.5	0.7	-0.1	0.0	-0.2	0.1	-0.5
Commuting to job workplace: Public transport	2.0	2.3	3.8	1.7	0.8	-0.7	1.7	1.4	1.6	1.9	1.9
Eye problems/disorders: Glaucoma	20.1	23.8	42.0	-6.5	-4.4	3.1	-5.2	-5.6	-5.6	0.3	-5.5
Medication: Blood pressure	2.7	5.1	7.4	-2.5	-0.2	1.9	-2.6	-2.5	-2.5	-2.1	-2.7
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.6	-0.6	-0.3	-1.0	-1.2	-1.1	-1.3	-1.1	-1.2
Supplements: Fish oil (including cod liver oil)	1.2	1.6	7.1	1.1	1.8	-0.9	0.4	0.3	0.4	-2.7	0.5
High cholesterol (Self-reported)	0.1	0.2	0.6	-0.1	0.8	0.2	0.3	0.4	0.5	-0.0	0.3
Medication: Bendroflumethiazide	3.7	5.7	9.5	-2.3	0.3	1.7	-3.0	-2.9	-3.0	-0.9	-3.1
Medication: Paracetamol	0.9	1.3	5.3	-1.3	-0.1	2.3	-0.9	-1.0	-0.9	0.4	-0.8
Medication: Lisinopril	0.1	0.1	0.5	-0.3	-0.4	0.7	-0.1	0.4	0.2	0.4	0.1
Medication: Atorvastatin	0.4	0.5	1.4	0.4	-0.6	-1.2	0.2	0.5	0.5	-1.1	0.4
Illnesses of father: High blood pressure	0.6	0.8	1.7	-0.6	0.6	0.0	-0.9	-1.2	-1.3	0.3	-1.2
Alcohol drinker status: Never	0.7	0.8	1.4	-0.7	-0.5	0.8	-1.1	-1.1	-1.2	0.2	-0.9
Ever smoked	1.5	2.7	4.9	1.7	2.2	-2.0	1.8	1.3	1.5	0.6	1.5
Basal metabolic rate	0.3	1.9	5.8	1.0	1.6	-2.4	0.9	1.0	0.9	-1.2	1.2
Leg fat percentage (left)	1.7	6.2	11.8	-3.4	-2.3	0.8	-2.8	-2.7	-2.8	-0.2	-3.0
Arm fat-free mass (left)	0.8	4.1	7.8	1.9	1.9	-2.8	1.8	1.9	1.9	-1.9	2.0
Number of operations (self-reported)	1.3	1.9	11.7	-0.0	0.5	-1.1	0.7	0.7	0.7	-3.4	0.8
Average weekly beer plus cider intake	0.6	0.9	4.9	0.1	0.4	1.5	-0.0	0.3	0.4	2.2	0.0
Irritability	1.2	2.0	10.1	-1.2	1.0	-0.2	-1.0	-1.0	-0.9	-3.2	-0.9
Risk taking	0.9	1.4	3.0	-1.2	-1.7	1.5	-1.2	-0.9	-1.0	-0.1	-1.1
Ever had prostate specific antigen (PSA) test	1.3	1.5	2.6	-1.6	-0.9	0.0	-1.1	-1.3	-1.1	-1.6	-1.3
Fractured/broken bones in last 5 years	0.8	1.0	2.5	-1.1	-0.3	0.6	-1.0	-0.9	-1.1	-1.6	-0.9
Age started oral contraceptive pill	1.4	1.7	2.9	1.5	0.7	-1.7	1.3	1.2	1.4	-1.2	1.3
Diastolic blood pressure, automated reading	0.1	0.2	0.3	0.1	0.5	-0.4	-0.6	-0.5	-0.5	-0.2	-0.4
Ever depressed for a whole week	0.8	0.9	3.7	-1.1	-1.9	1.1	-0.3	-0.7	-0.4	-0.2	-0.6
Unable to work because of sickness or disability	0.8	1.1	2.4	-1.3	-1.5	-0.4	-1.2	-0.7	-1.0	-0.7	-1.0
Commuting to job workplace: Cycle	0.4	0.5	1.5	1.1	0.1	-1.0	0.2	0.2	0.2	-1.2	0.4
Myopia	0.1	0.1	0.6	-0.6	0.8	-0.1	0.2	-0.2	-0.1	0.2	-0.1
Vascular/heart problems diagnosed by doctor	1.1	3.0	5.4	2.3	-0.4	-1.5	1.8	1.6	1.8	1.7	2.0
Cholesterol lowering medication	0.3	0.5	1.4	-0.3	-0.2	-0.3	-1.1	-0.5	-0.6	-1.2	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.0	0.7	0.1	0.6	0.3	0.4	0.3	1.0	0.1
Pain experienced in last month	0.9	1.6	2.8	1.4	0.5	-0.2	1.6	1.6	1.7	-0.3	1.5
Supplements: Calcium	1.1	1.2	2.2	-1.5	-1.2	0.7	-1.2	-0.9	-1.0	1.1	-1.1
Basal cell carcinoma (self-reported)	0.6	0.7	2.6	-0.0	-1.6	-0.0	0.6	0.9	0.8	1.0	0.5
Heart attack/myocardial infarction (self-reported)	2.8	3.6	12.0	1.9	1.5	-0.8	1.4	1.7	1.6	-3.5	1.6
Deep venous thrombosis (DVT) (self-reported)	2.8	3.7	6.8	-2.6	-1.7	2.3	-1.7	-1.8	-1.7	0.9	-2.1
Heart disease (siblings)	0.4	0.5	1.0	-0.0	0.6	-0.3	1.0	0.9	1.0	0.1	0.8
Alcohol drinker status: Previous	0.7	0.8	4.9	-0.6	-0.9	0.5	-0.1	-0.2	-0.3	2.2	-0.3
Pack years of smoking	0.6	0.8	2.3	-1.5	-0.8	1.0	-0.6	-0.6	-0.8	-0.7	-0.9
Impedance of whole body	0.1	0.6	2.7	1.0	0.4	0.6	0.3	0.4	0.3	1.6	0.3
Leg fat mass (left)	0.9	3.3	7.3	-2.7	-1.5	0.2	-2.1	-2.0	-2.1	-0.0	-2.1
Arm predicted mass (left)	0.7	3.4	7.9	1.6	1.6	-2.8	1.5	1.6	1.6	-1.9	1.7