TWAS hub - CPZ

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Head and Neck Squamous Cell Carcinoma	0.0348	0.0154	4.0e-03	0.000	0.011	-0.001	NA	0.000	3.2e-01	1.9e-02	4.4e-01	NA	3.1e-01
2	TCGA	Lung Squamous Cell Carcinoma	0.0881	0.0317	3.0e-04	0.012	0.027	0.007	NA	0.009	1.5e-02	4.4e-04	4.9e-02	NA	3.0e-02
3	TCGA	Prostate Adenocarcinoma	0.1049	0.0266	1.7e-09	0.117	0.103	0.125	NA	0.127	3.4e-12	6.1e-11	4.9e-13	NA	3.1e-13

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Height	6.5	125.7	148.8	12.2	11.8	9.4
Impedance of arm (right)	4.9	22.7	29.9	5.5	4.3	4.4
Standing height	4.6	45.3	61.9	7.9	6.8	5.3
Impedance of arm (left)	4.3	20.1	24.2	4.9	3.8	4.6
Comparative height size at age 10	4.3	23.9	43.3	6.6	4.2	3.4
Average weekly red wine intake	4.2	6.2	10.6	2.4	3.3	1.5
Sitting height	4.1	28.8	36.7	6.1	5.3	4.6
Tinnitus: Yes, now most or all of the time	3.5	4.1	5.1	2.0	2.3	1.7
Knee pain experienced in last month	3.3	5.1	8.0	-2.7	-2.8	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	3.1	6.5	10.3	3.2	2.3	1.9
Lung FVC	2.9	14.9	28.3	-2.9	-2.8	-5.3
Alcohol drinker status: Previous	2.9	3.3	5.3	-2.3	-1.9	-0.9
Number of full sisters	2.8	3.4	5.1	-2.2	-1.5	-1.7
Leg fat percentage (left)	2.8	10.2	12.5	-3.1	-2.9	-3.5
Medication: Lansoprazole	2.7	3.1	3.7	-1.8	-1.9	-1.5
Medication: Atorvastatin	2.6	3.2	5.8	-1.9	-0.6	-2.4
Average weekly beer plus cider intake	2.6	3.8	5.0	-1.2	-2.2	-2.2
Mouth/teeth dental problems	2.5	3.9	7.5	2.7	1.6	1.2
Leg fat percentage (right)	2.5	9.1	11.6	-2.8	-2.8	-3.4
Supplements: Vitamin C	2.5	3.0	6.3	-1.6	-2.5	-0.2
Alcohol intake frequency.	2.4	5.5	7.1	-2.7	-2.7	-1.5
Back pain experienced in last month	2.4	3.5	6.3	-1.8	-2.5	-1.0
Medication: Seretide 50 evohaler	2.3	2.7	6.8	-2.6	-0.9	-0.8
Ever had prostate specific antigen (PSA) test	2.3	2.7	3.0	1.4	1.7	1.7
Body mass index (BMI)	2.2	9.4	10.8	-3.3	-2.6	-3.2
Medication for pain relief, constipation, heartburn	2.2	3.8	6.2	2.0	2.5	1.1
Impedance of whole body	2.2	11.1	14.3	3.8	2.8	3.3
Maternal smoking around birth	2.1	3.0	6.5	-2.5	-1.1	-1.1
Overall health rating	2.1	4.4	7.5	-2.1	-2.7	-1.1
Multivitamins +/- minerals	2.0	2.6	6.2	0.0	-2.5	-1.3
Comparative body size at age 10	2.0	5.5	7.4	-2.7	-1.8	-2.4
Wears glasses or contact lenses	1.9	2.1	2.6	-1.4	-1.6	-1.4
Medication: Bendroflumethiazide	1.9	2.9	5.8	-1.3	-2.4	-1.1
Mouth/teeth dental problems: Dentures	1.8	3.1	4.0	-2.0	-1.7	-1.6
Medication: Allopurinol	1.8	2.4	3.9	-1.5	-1.1	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	3.0	-1.7	-1.7	-0.9
Pain experienced in last month	1.8	3.0	8.7	3.0	0.4	0.4
BMI	1.7	9.7	14.0	-3.7	-2.7	-2.8
Systolic blood pressure, automated reading	1.7	4.8	7.3	-0.9	-2.7	-2.5
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.7	4.6	-2.1	-0.6	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	3.0	-1.7	-0.7	-1.6
Ever had bowel cancer screening	1.7	2.0	2.9	1.2	1.2	1.7
Lupus	1.6	2.4	3.2	-1.7	-1.1	-1.8
Average weekly spirits intake	1.6	1.9	4.4	1.1	2.1	0.2
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	4.2	-1.0	-2.1	-0.1
Commuting to job workplace: Cycle	1.6	1.9	3.3	-1.8	-0.5	-1.5
Primary Biliary Cirrhosis	1.5	2.1	3.6	-1.1	-1.2	-1.9
Ever highly irritable/argumentative for 2 days	1.5	1.8	5.3	0.2	-2.3	0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.0	0.3	2.0	-0.8
Leg fat mass (left)	1.5	5.9	7.8	-2.4	-2.1	-2.8
Bipolar Disorder (2018)	1.4	2.2	5.2	-1.0	-2.3	-0.6
Pack years adult smoking proportion	1.4	2.2	4.4	-2.1	-1.4	0.2
Loud music exposure frequency	1.4	1.5	3.6	0.3	0.9	1.9
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	3.5	-1.4	-1.9	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	2.7	-1.6	-0.3	-1.7
Leg fat mass (right)	1.4	5.4	7.3	-2.2	-2.0	-2.7
Commuting to job workplace: Car/motor vehicle	1.4	1.6	3.8	2.0	0.2	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	3.6	-1.9	0.8	-0.9
Irritability	1.4	2.4	4.4	0.9	2.1	1.4
Pack years of smoking	1.4	2.1	4.3	-2.1	-1.3	0.4
Taking other prescription medications	1.3	2.0	4.8	-2.2	-0.7	-0.8
Diabetes (self-reported)	1.3	2.0	4.8	-2.2	-1.1	0.1
Asthma	1.3	2.5	4.9	-1.5	0.5	-2.2
Birth weight of first child	1.3	2.4	6.1	0.7	2.5	0.7
Number of children fathered	1.3	1.4	3.0	-0.7	0.9	1.7
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.4	0.9	1.2	1.5
Asthma (self-reported)	1.3	2.6	4.6	-1.8	-0.0	-2.1
Unable to work because of sickness or disability	1.3	1.7	2.4	-1.0	-1.6	-1.3
Prospective memory result	1.2	1.4	2.9	1.7	0.6	-1.0
Health satisfaction	1.2	1.6	4.5	-0.2	-2.1	0.4
Had major operations	1.2	1.4	3.7	0.2	0.7	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	2.5	-1.6	-0.4	-1.3
Mother’s age at death	1.2	1.4	2.7	1.1	-0.7	-1.6
Financial situation satisfaction	1.2	1.5	3.9	-0.6	-0.4	2.0
Lung FEV1/FVC ratio	1.1	5.3	11.2	1.4	1.7	3.4
Pulse rate	1.1	1.9	2.3	1.4	1.5	-1.2
Qualifications: nursing, teaching	1.1	1.8	5.0	2.2	0.5	0.1
Eye problems/disorders: Glaucoma	1.1	1.3	2.5	-1.6	0.4	-1.1
Number of treatments/medications taken	1.0	1.8	2.8	-1.7	-1.5	0.6
Diabetes (father)	1.0	1.3	1.8	-1.3	-1.3	-0.6
Townsend deprivation index at recruitment	1.0	1.5	3.4	-1.8	-0.9	-0.3
Waist circumference	1.0	3.7	4.9	-2.2	-1.3	-2.2
Noisy workplace	1.0	1.2	1.8	-1.3	-1.3	0.4
Medication: Paracetamol	1.0	1.7	2.5	-1.6	-1.5	-0.5
Suffer from ‘nerves’	1.0	1.6	3.5	-1.9	-0.3	-1.1
Chest pain or discomfort	1.0	1.4	3.3	-0.8	0.4	1.8
Arm fat percentage (left)	1.0	3.9	4.8	-2.2	-1.5	-2.1
Friendships satisfaction	1.0	1.2	1.6	-1.0	-1.3	-1.0
Hearing aid user	1.0	1.1	2.4	0.8	1.5	-0.5
Crohns Disease (2017)	0.9	2.1	3.7	1.6	0.3	1.9
LDL Cholesterol	0.9	1.5	4.1	-2.0	-0.6	-0.2
Neuroticism (2016)	0.9	1.3	3.4	0.7	1.8	0.1
Type 2 Diabetes (T2D) (2018)	0.9	1.6	3.9	-2.0	-1.0	-0.2
Medication: Levothyroxine sodium	0.9	1.6	3.3	-1.8	-1.1	-0.5
Arm fat percentage (right)	0.9	3.4	4.8	-1.9	-1.3	-2.2
Happiness	0.9	1.1	1.6	0.1	-1.2	-1.3
Breastfed as a baby	0.9	1.1	2.7	0.6	0.4	1.6
Tense / ‘highly strung’	0.9	1.5	2.8	-1.7	-1.0	-0.9
Gout (self-reported)	0.9	1.2	2.4	-1.1	-0.3	-1.6
Medication: Aspirin	0.9	1.1	2.4	-0.9	-1.6	0.3
Illnesses of siblings: Diabetes	0.9	1.1	2.3	-1.5	1.0	0.3
Long-standing illness, disability or infirmity	0.9	1.4	3.8	-1.9	-0.7	0.3
Medication: Aspirin	0.9	1.1	3.0	-0.5	-1.7	-0.3
Cholesterol lowering medication	0.9	1.3	2.1	-1.4	0.9	1.0
Irritable Bowel Disease (IBD)	0.8	1.9	4.7	2.2	0.0	1.1
Mean Putamen Volume	0.8	1.0	2.6	1.6	-0.3	0.3
Triglycerides	0.8	1.2	1.7	-1.2	-1.3	-0.8
Hand grip strength (left)	0.8	2.2	4.6	2.1	1.4	-0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.1	-0.8	-0.9	1.0
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.6	0.2	-1.2	1.3
Qualifications: None of the above	0.8	1.8	4.4	-0.9	-2.1	-0.5
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.2	1.5	-0.2	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	4.7	2.2	1.5	0.4
Glaucoma (self-reported)	0.8	0.9	1.9	-1.4	-0.7	-0.6
Wheeze or whistling in the chest in last year	0.8	1.5	4.1	-2.0	-0.3	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.4	0.5	1.6	0.2
Heart disease (mother)	0.8	1.0	2.0	0.6	1.4	0.8
Commuting to job workplace: Public transport	0.8	1.0	1.7	-1.3	-0.1	1.1
Medication: Paracetamol	0.8	1.3	3.1	-1.8	-0.7	0.5
Risk taking	0.8	1.2	2.1	-0.1	-1.4	-1.2
Diastolic blood pressure, automated reading	0.8	2.6	5.7	0.4	-2.4	-1.4
Hearing difficulty/problems: Yes	0.7	1.0	1.9	1.4	0.7	0.8
Vitamin and mineral supplements	0.7	0.9	2.6	0.2	1.6	0.3
Supplements: Zinc	0.7	0.7	0.8	-0.9	0.8	0.9
Medication: Metformin	0.7	1.0	2.6	-1.6	0.1	-0.7
Pain all over the body in last month	0.7	0.8	1.5	-1.2	0.3	-0.8
Time employed in main current job	0.7	0.8	0.9	1.0	0.8	-0.9
Worrier / anxious feelings	0.7	1.2	2.1	0.7	1.5	1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.9	1.7	0.2	1.2
Exposure to tobacco smoke at home	0.7	0.8	1.7	1.3	-0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.7	0.9	1.9	-1.4	0.4	-0.7
Eye problems/disorders: None of the above	0.7	0.8	1.9	1.4	0.6	-0.3
Emphysema/chronic bronchitis	0.7	0.8	1.5	-0.5	0.9	1.2
Medication: Omeprazole	0.7	0.8	1.7	-0.8	-1.3	-0.2
Leg pain on walking	0.7	0.9	2.0	-0.6	0.6	1.4
Diabetes diagnosed by doctor	0.7	1.1	2.4	-1.5	-1.0	0.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.4	-1.2	-0.3	-1.1
Illnesses of father: High blood pressure	0.7	0.9	2.6	1.6	0.4	-0.2
Age started oral contraceptive pill	0.7	0.9	2.6	0.3	1.6	0.3
Fasting Glucose	0.6	0.7	1.3	-0.2	1.1	0.9
Respiratory disease	0.6	1.3	1.5	-0.9	1.2	-1.2
Sensitivity / hurt feelings	0.6	1.1	2.5	0.2	1.6	0.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.3	-1.1	-0.1	1.0
Medication for hormone replacement therapy	0.6	0.6	1.3	1.1	0.4	-0.6
Diabetes (mother)	0.6	0.7	1.7	-1.3	0.3	0.6
Current tobacco smoking	0.6	0.9	2.8	-1.7	0.1	0.2
Relative age voice broke	0.6	0.9	2.2	-1.5	0.5	0.6
Financial difficulties in last 2 years	0.6	0.8	1.6	-0.9	0.0	1.3
Fluid intelligence score	0.6	1.2	2.2	-1.5	-0.4	-1.1
Falls in the last year	0.6	0.8	1.6	-0.7	0.4	1.3
Medication: Cholesterol lowering	0.6	1.0	2.2	-0.1	-0.8	-1.5
Peak expiratory flow (PEF)	0.6	1.4	3.3	1.8	0.4	0.8
Pulse wave reflection index	0.6	0.7	1.5	-1.2	-0.9	-0.1
Medication: Amlodipine	0.6	0.8	1.4	-0.2	-0.9	-1.2
Forced vital capacity (FVC), Best measure	0.6	2.3	3.5	1.8	1.9	-0.2
Body fat percentage	0.6	2.5	3.6	-1.5	-1.2	-1.9
Number of full brothers	0.6	0.7	1.3	-0.9	0.2	1.2
Angina (self-reported)	0.6	0.7	1.4	-1.2	0.8	0.4
Migraine (self-reported)	0.6	0.7	1.8	-0.6	-0.2	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	0.2	-0.3	1.4
Arm fat mass (left)	0.6	2.3	3.3	-1.5	-1.1	-1.8
High cholesterol (Self-reported)	0.6	1.1	2.0	-1.0	0.5	-1.4
Ever depressed for a whole week	0.6	0.8	2.1	0.1	0.6	1.4
Myopia	0.6	0.9	1.8	0.8	-1.4	-0.3
Supplements: Calcium	0.6	0.6	1.7	-0.3	-0.4	1.3
Heart disease (siblings)	0.6	0.8	1.0	-1.0	-0.7	-0.9
Prostate Cancer	0.5	0.7	1.5	0.3	0.7	1.2
Body Mass Index (BMI) (2010)	0.5	0.6	1.1	-0.9	-1.0	0.1
Systolic Blood Pressure	0.5	2.7	5.6	0.4	-1.6	-2.4
Neuroticism	0.5	1.1	1.5	-0.8	1.2	1.2
Relative age of first facial hair	0.5	1.1	2.2	-0.4	1.5	0.9
Angina	0.5	0.7	1.6	-1.3	0.6	0.3
Hand grip strength (right)	0.5	1.2	2.6	0.9	-0.6	-1.6
Fed-up feelings	0.5	1.0	1.2	-1.1	1.1	-0.8
Medication: Atenolol	0.5	0.6	1.1	1.0	0.9	-0.3
Nervous feelings	0.5	0.9	1.3	-1.1	-1.0	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.0	0.4	1.4	0.1
Forced vital capacity (FVC)	0.5	2.1	3.9	1.4	2.0	-0.6
Medication: Ramipril	0.5	0.6	1.4	1.2	-0.2	0.5
Illnesses of siblings	0.5	0.7	1.6	1.3	-0.4	-0.6
Hip circumference	0.5	2.1	4.0	-1.1	-1.1	-2.0
Number of live births	0.5	0.7	1.3	-0.2	-0.8	1.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	3.2	1.8	1.4	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.6	-0.6	-1.3	0.0
Pulse wave Arterial Stiffness index	0.5	0.6	1.2	-0.5	0.6	1.1
Arm fat mass (right)	0.5	2.0	3.3	-1.3	-1.0	-1.8
Length of working week for main job	0.5	0.6	1.3	-0.6	-0.1	-1.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.4	-1.2	0.5	0.9
Birth weight	0.5	1.1	1.3	1.2	1.0	1.0
High blood pressure (siblings)	0.5	0.8	2.1	-0.5	-1.4	-0.0
Age at first live birth	0.5	0.9	1.2	1.1	0.8	-0.9
Eye problems/disorders: Cataract	0.5	0.6	1.7	0.0	-0.1	1.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.1	-1.1	1.0	0.3
Mineral and other dietary supplements	0.5	0.7	1.4	-0.8	0.3	-1.2
Miserableness	0.5	0.9	1.7	-0.5	0.9	-1.3
Alcohol drinker status: Never	0.5	0.6	0.9	-0.3	-0.8	-1.0
Bipolar Disorder or Schizophrenia	0.4	1.0	2.9	-0.4	-1.7	-0.3
Depressed Affect (Nagel 2018)	0.4	0.7	1.6	-1.3	0.8	0.0
Alzheimer’s Disease (in father)	0.4	0.4	1.1	0.1	1.1	-0.4
Ulcerative Colitis (UC)	0.4	0.7	1.8	1.3	-0.5	-0.3
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.7	-1.6	0.0	-0.3
Breast Cancer	0.4	1.0	2.2	-1.5	-0.8	-0.3
HDL Cholesterol	0.4	0.6	1.8	1.3	0.2	0.1
Blood Red Count	0.4	3.7	5.5	1.7	1.7	2.4
Chronotype (morning person)	0.4	0.9	2.2	-0.6	-0.3	-1.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.4	-1.2	0.4	-0.1
Impedance of leg (right)	0.4	1.7	3.1	1.8	1.0	1.1
Average weekly fortified wine intake	0.4	0.5	1.2	-0.4	1.1	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.1	-0.6	-0.5	-1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	0.9	0.5	0.4	-1.0
Supplements: Glucosamine	0.4	0.6	0.9	0.7	-0.5	1.0
High blood pressure (mother)	0.4	0.5	1.0	0.7	0.3	-1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.6	-0.8	-0.7	0.6
Trunk fat-free mass	0.4	2.4	3.7	1.9	1.9	0.3
Alcohol intake versus 10 years previously	0.4	0.6	1.0	-0.9	0.0	-1.0
Father’s age at death	0.4	0.5	1.0	1.0	-0.5	-0.5
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	0.6	1.2	-0.1
Trunk predicted mass	0.4	2.4	3.6	1.9	1.9	0.3
Hair/balding pattern: Pattern 4	0.4	1.0	2.7	-0.4	0.4	-1.7
Pulse wave peak to peak time	0.4	0.5	0.9	0.8	-0.1	-0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.3	-1.1	0.4	-0.3
Family relationship satisfaction	0.4	0.4	0.6	-0.8	-0.7	0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.0	0.3	-0.5	-1.0
Leg fat-free mass (right)	0.4	1.9	3.3	1.4	1.8	0.6
Mood swings	0.4	0.7	1.4	-1.2	0.5	0.6
Smoking status: Current	0.4	0.6	1.8	-1.3	0.2	0.1
Number of self-reported non-cancer illnesses	0.4	0.7	1.6	-1.2	-0.5	-0.4
Medication: Lisinopril	0.4	0.5	0.7	0.8	0.2	-0.9
Ever smoked	0.4	0.8	1.7	-1.3	0.7	-0.2
Number of operations (self-reported)	0.4	0.6	1.4	-0.6	-0.3	-1.2
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.4	-1.5	-0.1	-0.3
Neuroticism (Nagel 2018)	0.3	0.6	1.0	-1.0	0.9	0.3
Blood Platelet Count	0.3	3.5	6.1	-2.5	-1.4	-1.6
Waist Hip Ratio (WHR)	0.3	1.1	2.2	0.2	1.5	1.1
Allergy or Eczema	0.3	0.9	1.1	0.6	1.1	1.0
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	1.0	-0.2	-0.2
Medication: Co-codamol	0.3	0.3	0.8	-0.4	0.9	0.3
Severe depression (siblings)	0.3	0.3	0.5	-0.4	0.5	-0.7
High blood pressure	0.3	0.9	2.2	-0.0	-1.5	-0.7
Chronic bronchitis/emphysema (father)	0.3	0.3	0.7	-0.5	0.9	0.1
Leg predicted mass (left)	0.3	1.5	2.6	1.4	1.6	0.3
Number of incorrect matches in round	0.3	0.5	0.6	0.8	0.5	-0.8
Past tobacco smoking	0.3	0.5	0.8	0.9	-0.6	0.5
Hair/balding pattern: Pattern 2	0.3	0.4	0.7	-0.9	-0.6	0.4
Had other major operations	0.3	0.3	0.6	-0.8	0.6	0.2
Heart attack	0.3	0.4	0.8	-0.9	-0.5	-0.3
Allergy	0.3	0.7	2.1	1.5	0.1	-0.2
Neuroticism score	0.3	0.6	0.9	-1.0	0.8	0.6
Lung cancer (father)	0.3	0.3	0.6	-0.4	-0.3	0.8
Illnesses of mother	0.3	0.4	1.1	-0.2	0.2	1.0
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.8	-0.8	-0.1	0.9
Blood clot in the leg (DVT)	0.3	0.4	0.8	-0.9	0.1	-0.8
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.0	-1.0	-0.7	-0.3
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.1	-0.2	0.1	1.0
Medication: Blood pressure	0.3	0.5	1.4	1.2	-0.1	0.0
Medication: Ibuprofen	0.3	0.4	0.4	-0.6	-0.6	0.6
Whole body fat-free mass	0.3	1.7	2.9	1.5	1.7	0.2
Whole body water mass	0.3	1.4	2.4	1.4	1.6	0.1
Leg predicted mass (right)	0.3	1.8	3.0	1.4	1.7	0.5
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	0.7	-0.1	0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.9	-1.0	-0.6	-0.0
Worry (Nagel 2018)	0.2	0.5	1.3	-1.1	0.2	-0.4
Alzheimer’s Disease (in mother)	0.2	0.2	0.5	-0.3	-0.4	-0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	-0.7	-0.1	-0.5
Age at First Birth	0.2	0.3	0.5	-0.3	0.7	0.6
HbA1C	0.2	0.2	0.4	-0.1	-0.5	0.7
Leg fat-free mass (left)	0.2	1.2	2.0	1.3	1.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.7	0.6	0.8	-0.7
Impedance of leg (left)	0.2	1.2	2.1	1.4	0.9	0.9
Alcohol usually taken with meals	0.2	0.3	0.7	-0.1	0.8	-0.4
Hearing difficulty/problems with background noise	0.2	0.3	0.9	-0.0	-0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	0.6	1.0	-0.5
Depression (self-reported)	0.2	0.3	0.3	-0.4	0.5	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.2	-0.8	0.3
Shortness of breath walking on level ground	0.2	0.2	0.4	-0.1	-0.4	0.6
Qualifications: College or University degree	0.2	0.6	1.2	1.1	0.7	-0.3
Whole body fat mass	0.2	1.0	1.8	-0.9	-0.5	-1.3
Age at last live birth	0.2	0.2	0.4	0.7	-0.5	-0.2
Hypertension (Self-reported)	0.2	0.6	1.4	0.5	-1.2	-0.3
Illnesses of father: Heart disease	0.2	0.3	0.7	0.4	-0.8	0.4
Smoking status: Previous	0.2	0.3	0.4	-0.3	0.6	-0.7
Loneliness, isolation	0.2	0.3	0.9	0.2	-0.9	-0.1
Osteoarthritis (self-reported)	0.2	0.2	0.6	-0.3	-0.7	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.3	0.4	-0.7	0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.0	1.0	-0.3	-0.6
Guilty feelings	0.2	0.3	0.4	-0.6	0.3	0.5
Medication: Blood pressure	0.2	0.3	0.8	0.1	-0.9	-0.4
Basal metabolic rate	0.2	1.0	1.7	1.2	1.3	-0.2
Fractured/broken bones in last 5 years	0.2	0.2	0.5	0.3	0.7	0.3
Vascular/heart problems diagnosed by doctor	0.2	0.7	1.6	0.3	1.3	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.4	-0.6	-0.0	-0.6
Depression (Nagel 2018)	0.1	0.1	0.2	0.2	0.4	-0.2
Reaction Time	0.1	0.3	0.5	0.2	-0.5	-0.7
Ovarian Cancer	0.1	0.2	0.4	-0.1	-0.3	0.6
Schizophrenia (2014)	0.1	0.2	0.3	0.3	-0.5	0.4
Blood White Count	0.1	0.8	2.0	-0.6	0.3	-1.4
Heel T-Score	0.1	0.5	1.1	0.6	0.1	-1.1
Smoking Status	0.1	0.3	0.4	-0.6	0.4	0.6
Cardiovascular Disease	0.1	0.4	0.9	0.5	-0.2	-0.9
Trunk fat percentage	0.1	0.3	0.7	-0.3	-0.1	-0.8
Qualifications: CSEs or equivalent	0.1	0.1	0.4	-0.1	0.1	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.9	-0.1	0.2	0.9
Stomach or abdominal pain in last month	0.1	0.1	0.4	0.2	0.1	0.6
Weight	0.1	0.3	0.4	0.4	0.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	-0.1	0.6	0.1
Arm fat-free mass (right)	0.1	0.3	0.6	-0.1	0.5	-0.8
Exposure to tobacco smoke outside home	0.1	0.1	0.2	-0.4	0.4	0.2
Worry too long after embarrassment	0.1	0.1	0.2	-0.2	-0.5	0.3
Neck or shoulder pain in last month	0.1	0.2	0.6	-0.8	0.1	-0.0
Mean time to correctly identify matches	0.1	0.1	0.2	-0.4	-0.5	-0.1
Arm predicted mass (right)	0.1	0.4	0.9	0.0	0.7	-0.9
Pulse rate, automated reading	0.1	0.3	0.6	0.8	-0.0	-0.5
Medication for cholesterol	0.1	0.1	0.2	0.4	0.3	-0.3
Medication: Gliclazide	0.1	0.1	0.2	-0.1	-0.4	-0.4
Average weekly champagne plus white wine intake	0.1	0.1	0.2	0.2	0.4	0.2
Arm fat-free mass (left)	0.1	0.7	1.0	0.2	1.0	-1.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.4	-0.0	0.1	0.6
Arm predicted mass (left)	0.1	0.5	0.8	0.2	0.7	-0.9
Schizophrenia (2018)	0.0	0.1	0.2	0.2	-0.4	-0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.2	0.3	-0.3	-0.5	-0.5
Hypothyroidism (self reported)	0.0	0.0	0.0	-0.2	-0.1	0.0
Hair Pigment	0.0	0.5	1.0	-0.0	0.8	1.0
Tanning	0.0	0.1	0.4	-0.6	-0.0	0.1
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.0	-0.1	-0.2	0.1
Age when periods started (menarche)	0.0	0.1	0.2	-0.2	0.3	0.4
Serious illness, injury or assault to yourself	0.0	0.0	0.1	0.0	-0.0	0.3
Trunk fat mass	0.0	0.2	0.6	-0.0	0.1	-0.8
Had menopause	0.0	0.0	0.1	-0.3	0.1	0.2
Medication: Simvastatin	0.0	0.1	0.1	-0.2	0.2	0.3
Headache pain in last month	0.0	0.0	0.0	-0.1	-0.1	-0.1
Commuting to job workplace: Walk	0.0	0.1	0.1	0.1	0.3	0.3
Breast cancer (self-reported)	0.0	0.0	0.0	0.2	-0.2	-0.0
Osteoporosis (self-reported)	0.0	0.1	0.1	0.2	-0.3	-0.2
Ever taken oral contraceptive pill	0.0	0.0	0.1	-0.2	0.0	-0.3

Hub : Genes

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Trait associations