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chr17:55,903,829-57,989,860

Best TWAS P=8.26e-09 · Best GWAS P=2.06e-08 conditioned to 0.0865

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	TRIM37	0.18	0.22	enet	25	0.24	6.9e-20	-5.3	5.2	2.4e-07	-0.87	0.07	0.93	FALSE
2	GTEx	Adipose Subcutaneous	AC099850.1	0.04	0.06	lasso	1	0.05	5.2e-05	-5.3	5.3	1.1e-07	-0.89	0.04	0.95	FALSE
3	GTEx	Adipose Visceral Omentum	TRIM37	0.19	0.25	lasso	5	0.25	3.1e-13	-5.4	5.3	9.7e-08	-0.90	0.04	0.96	FALSE
4	GTEx	Breast Mammary Tissue	TRIM37	0.26	0.17	enet	33	0.17	3.7e-09	-5.6	5.5	3.2e-08	-0.82	0.04	0.96	FALSE
5	GTEx	Breast Mammary Tissue (Female)	TRIM37	0.18	0.08	lasso	1	0.02	8.2e-02	-5.6	5.6	2.1e-08	-0.91	0.04	0.81	FALSE
6	GTEx	Cells Transformed fibroblasts	RP11-112H10.4	0.04	0.02	lasso	2	0.02	1.9e-02	-5.4	5.3	1.2e-07	-0.89	0.06	0.84	FALSE
7	GTEx	Colon Transverse	TRIM37	0.14	0.15	lasso	6	0.17	1.5e-08	-5.4	5.1	3.0e-07	-0.83	0.05	0.95	FALSE
8	GTEx	Esophagus Muscularis	AC099850.1	0.06	0.00	enet	22	0.00	1.7e-01	-5.4	5.6	1.9e-08	-0.84	0.03	0.83	FALSE
9	GTEx	Nerve Tibial	SMG8	0.08	0.06	lasso	7	0.05	1.0e-04	-5.4	5.3	1.2e-07	-0.88	0.05	0.92	FALSE
10	GTEx	Pancreas	TRIM37	0.08	0.05	lasso	7	0.02	3.2e-02	-5.3	5.6	2.3e-08	-0.86	0.05	0.84	FALSE
11	GTEx	Spleen	TRIM37	0.13	0.08	enet	16	0.18	2.8e-05	-5.4	5.8	8.3e-09	-0.79	0.05	0.84	TRUE
12	GTEx	Testis	TRIM37	0.17	0.23	lasso	6	0.19	6.3e-09	-5.1	-5.1	3.1e-07	0.80	0.10	0.90	FALSE
13	GTEx	Whole Blood	TRIM37	0.12	0.18	enet	21	0.18	1.8e-16	-5.1	5.3	1.4e-07	-0.89	0.06	0.94	FALSE
14	METSIM	Adipose	TRIM37	0.11	0.11	bslmm	328	0.12	2.0e-17	-5.4	5.3	1.3e-07	-0.86	0.05	0.95	FALSE
15	NTR	Blood	TRIM37	0.02	0.03	lasso	4	0.03	6.4e-11	-5.4	5.4	6.1e-08	-0.90	0.06	0.94	FALSE
16	The Cancer Genome Atlas	Soft Tissue Sarcoma	MTMR4	0.07	0.00	blup	40	0.03	6.6e-03	4.8	-5.7	1.0e-08	0.77	0.01	0.60	FALSE