[Hub]/) : Traits : High blood pressure (siblings) : ←

chr16:30,347,731-31,833,122

Best TWAS P=3.51e-08 · Best GWAS P=4.68e-08 conditioned to 0.183

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF646	0.04	0.06	lasso	7	0.04	4.5e-06	-5.3	5.4	5.2e-08	-0.93	0.02	0.98	FALSE
2	GTEx	Adipose Visceral Omentum	KAT8	0.07	0.02	lasso	5	0.02	4.0e-02	-5.3	5.5	3.5e-08	-0.87	0.02	0.94	TRUE
3	GTEx	Artery Aorta	KAT8	0.23	0.20	lasso	4	0.20	2.7e-11	-5.3	5.3	9.2e-08	-0.90	0.02	0.98	FALSE
4	GTEx	Artery Coronary	KAT8	0.22	0.19	lasso	2	0.19	6.6e-07	-5.3	5.3	1.2e-07	-0.89	0.02	0.96	FALSE
5	GTEx	Brain Cerebellar Hemisphere	KAT8	0.12	0.23	lasso	3	0.18	2.9e-05	-5.3	5.3	1.2e-07	-0.92	0.02	0.90	FALSE
6	GTEx	Brain Cerebellum	KAT8	0.21	0.01	lasso	9	0.05	1.4e-02	-5.3	5.3	1.3e-07	-0.79	0.03	0.88	FALSE
7	GTEx	Brain Cortex	KAT8	0.14	0.14	lasso	3	0.10	8.9e-04	-4.8	5.3	1.3e-07	-0.93	0.03	0.86	FALSE
8	GTEx	Brain Frontal Cortex BA9	KAT8	0.16	0.20	lasso	1	0.17	2.6e-05	-5.2	5.2	2.6e-07	-0.91	0.02	0.92	FALSE
9	GTEx	Heart Atrial Appendage	KAT8	0.12	0.02	lasso	4	0.01	1.6e-01	-5.1	5.3	1.3e-07	-0.69	0.05	0.62	FALSE
10	GTEx	Liver	VKORC1	0.22	0.20	lasso	5	0.22	1.1e-06	-5.1	5.3	1.2e-07	-0.97	0.02	0.98	FALSE
11	GTEx	Ovary	KAT8	0.16	0.09	lasso	4	0.06	1.2e-02	-5.3	5.2	2.0e-07	-0.86	0.02	0.83	FALSE
12	GTEx	Whole Blood	HSD3B7	0.06	0.06	lasso	4	0.06	2.6e-06	-5.5	-5.5	4.9e-08	0.99	0.02	0.98	FALSE
13	GTEx	Whole Blood	ZNF668	0.05	0.06	lasso	3	0.06	5.9e-06	-5.2	-5.2	2.5e-07	0.87	0.02	0.98	FALSE
14	NTR	Blood	BCKDK	0.01	0.00	bslmm	242	0.01	2.5e-03	-5.1	-5.3	1.2e-07	0.79	0.02	0.94	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	KAT8	0.13	0.16	lasso	5	0.16	4.2e-20	-5.2	5.1	2.8e-07	-0.88	0.02	0.98	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	ZNF646	0.06	0.01	bslmm	233	0.01	1.1e-02	-5.3	5.4	5.2e-08	-0.84	0.02	0.98	FALSE
17	YFS	Blood	ZNF668	0.10	0.12	bslmm	232	0.12	1.5e-36	-5.1	-5.2	1.8e-07	0.95	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	MYST1	0.18	0.07	blup	35	0.11	4.2e-04	-5.1	5.3	1.2e-07	-0.91	0.02	0.89	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	VKORC1	0.03	0.04	lasso	3	0.04	3.2e-05	-5.3	5.4	8.1e-08	-0.95	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF668	0.02	0.02	blup	32	0.02	2.9e-03	-5.2	-5.4	8.2e-08	0.93	0.01	0.94	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF668	0.02	0.01	enet	8	0.02	3.1e-03	-5.1	-5.2	1.7e-07	0.88	0.02	0.82	FALSE
22	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MYST1	0.03	0.05	blup	34	0.03	2.1e-03	-5.1	5.3	1.0e-07	-0.92	0.02	0.92	FALSE
23	The Cancer Genome Atlas	Rectum Adenocarcinoma	MYST1	0.13	0.05	blup	35	0.06	1.9e-02	-5.3	5.2	1.9e-07	-0.90	0.01	0.62	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MYST1	0.13	0.06	blup	34	0.12	6.8e-05	-5.1	5.2	2.5e-07	-0.89	0.02	0.95	FALSE