TWAS hub - ACAD10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0740	0.0292	1.6e-05	0.008	0.022	0.016	0.023	0.004	0.00062	5.3e-08	2.9e-06	4.3e-08	0.010
2	TCGA	Brain Lower Grade Glioma	0.0182	0.0143	6.1e-03	0.025	0.010	0.003	NA	0.015	0.00068	2.1e-02	1.2e-01	NA	0.007

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Eosinophil Count	60.3	464.7	630.0	-17.3	-25.1
Hypothyroidism (self reported)	54.6	125.4	148.8	-10.1	-12.2
Medication: Levothyroxine sodium	44.3	75.1	85.6	-8.0	-9.2
Hypothyroidism/myxoedema (self-reported)	42.6	83.1	96.8	-8.3	-9.8
Blood Platelet Count	33.1	383.6	676.0	-26.0	-9.6
Blood White Count	31.9	236.4	331.2	-11.9	-18.2
Coronary Artery Disease (CAD)	19.8	23.6	27.7	-4.4	-5.3
Systolic Blood Pressure	13.9	69.5	86.9	-7.2	-9.3
Mean time to correctly identify matches	13.5	25.6	31.3	-4.5	-5.6
Diastolic blood pressure, automated reading	13.3	41.2	51.6	-5.5	-7.2
Blood Red Count	13.2	127.6	127.8	-11.3	-11.3
Reaction Time	12.6	23.9	32.3	-4.0	-5.7
Smoking status: Previous	12.6	18.8	27.3	-3.2	-5.2
Pulse wave Arterial Stiffness index	12.5	14.6	25.9	-5.1	-1.8
Medication: Atenolol	12.1	15.1	18.9	-3.4	-4.4
Pulse wave peak to peak time	11.8	13.9	24.8	5.0	1.7
LDL Cholesterol	10.3	16.3	21.8	3.3	4.7
Systolic blood pressure, automated reading	10.2	29.7	35.3	-4.9	-5.9
Medication for cholesterol	10.1	15.4	18.4	3.5	4.3
Birth weight of first child	10.0	18.2	21.8	3.8	4.7
Heart attack/myocardial infarction (self-reported)	9.2	11.9	12.5	-3.5	-3.4
Past tobacco smoking	9.1	16.7	23.6	3.2	4.9
Medication: Blood pressure	8.9	16.9	20.6	-3.6	-4.5
Heart attack	8.8	11.3	12.7	-3.6	-3.1
Birth weight	8.8	19.1	20.4	4.5	4.2
Vascular/heart problems diagnosed by doctor	8.3	22.7	27.5	4.2	5.2
Cardiovascular Disease	7.9	26.2	33.3	-4.4	-5.8
Diverticular disease/diverticulitis (self-reported)	7.9	9.3	11.9	2.6	3.5
HbA1C	7.5	8.4	9.6	3.1	2.7
Medication: Ibuprofen (e.g. Nurofen)	7.5	9.6	10.2	3.0	3.2
Primary Biliary Cirrhosis	7.4	10.6	14.2	-2.6	-3.8
Taking other prescription medications	7.2	11.2	12.4	-3.1	-3.5
High blood pressure	7.2	20.2	27.2	-3.6	-5.2
Cholesterol lowering medication	7.2	10.6	12.0	-3.5	-3.0
Heart disease (mother)	6.7	8.1	12.2	-2.0	-3.5
Illnesses of father: None of the above (group 1)	6.3	7.7	7.9	2.8	2.8
Allergy or Eczema	6.2	16.4	20.7	4.5	3.5
Hayfever, allergic rhinitis or eczema	6.2	13.4	17.2	4.1	3.1
Rheumatoid Arthritis	6.1	8.4	8.6	-2.9	-2.9
Headache pain in last month	6.1	10.5	18.7	1.5	4.3
Chronotype (morning person)	5.8	13.3	22.5	-2.0	-4.7
Hearing difficulty/problems: Yes	5.7	8.7	10.6	-3.3	-2.6
Hypertension (Self-reported)	5.7	15.9	20.1	-3.4	-4.5
Number of self-reported non-cancer illnesses	5.7	9.9	11.8	-2.8	-3.4
Ever smoked	5.4	9.6	15.4	-1.9	-3.9
Number of treatments/medications taken	5.3	9.6	10.8	-2.9	-3.3
Medication: Blood pressure	5.2	9.2	9.3	-3.0	-3.1
Arm fat-free mass (left)	5.1	25.8	37.9	3.7	6.2
Arm predicted mass (left)	5.1	25.8	38.3	3.6	6.2
Depression (Nagel 2018)	4.9	7.4	10.3	2.1	3.2
Back pain experienced in last month	4.8	7.0	9.1	2.2	3.0
Medication: Ibuprofen	4.7	5.6	6.2	2.2	2.5
Relative age voice broke	4.5	6.9	11.6	-3.4	-1.5
Medication: Bendroflumethiazide	4.5	6.9	8.5	-2.9	-2.3
Allergy	4.4	10.1	14.0	-3.7	-2.5
Illnesses of siblings	4.4	6.1	8.5	2.9	1.9
Friendships satisfaction	4.4	5.5	10.4	3.2	0.7
Medication: Ramipril	4.3	5.5	7.2	-2.7	-1.9
Arm fat-free mass (right)	4.3	22.0	31.7	3.5	5.6
Trunk fat-free mass	4.2	24.2	35.0	3.6	5.9
Trunk predicted mass	4.2	24.2	35.3	3.6	5.9
Whole body water mass	4.2	23.8	33.5	3.7	5.8
Arm predicted mass (right)	4.1	20.9	30.4	3.4	5.5
Whole body fat-free mass	4.1	23.4	32.9	3.7	5.7
Basal metabolic rate	4.1	22.5	33.2	3.4	5.8
Hip circumference	3.8	16.6	25.6	2.8	5.1
Frequency of tiredness / lethargy in last 2 weeks	3.8	6.2	12.4	0.0	3.5
Number of full brothers	3.8	4.7	9.5	-0.1	3.1
Lupus	3.7	5.5	7.9	-1.8	-2.8
High blood pressure (siblings)	3.7	5.3	7.2	-2.7	-1.9
Medication: Allopurinol	3.7	4.9	7.4	-1.6	-2.7
Father’s age at death	3.6	4.8	9.5	0.5	3.1
Comparative height size at age 10	3.6	19.6	32.6	2.6	5.7
Had major operations	3.6	4.2	7.0	-2.6	-1.2
Smoking Status	3.5	8.5	10.0	-3.2	-2.6
Pack years adult smoking proportion	3.5	5.3	5.6	2.2	2.4
Leg fat-free mass (left)	3.5	18.4	25.2	3.4	5.0
Frequency of unenthusiasm / disinterest in last 2 weeks	3.5	4.6	6.5	1.7	2.5
Pain experienced in last month	3.5	5.9	11.4	-0.6	-3.4
Ulcerative Colitis (UC)	3.4	6.4	9.4	-1.9	-3.1
Leg predicted mass (left)	3.4	18.2	24.7	3.4	5.0
Irritable Bowel Disease (IBD)	3.3	7.9	11.5	-2.1	-3.4
Impedance of arm (left)	3.3	15.5	16.0	-4.0	-3.9
Alcohol intake versus 10 years previously	3.2	4.8	7.1	-1.6	-2.7
Leg fat-free mass (right)	3.2	17.0	21.3	3.6	4.6
Loneliness, isolation	3.2	4.4	6.6	1.5	2.6
Leg predicted mass (right)	3.2	16.9	20.9	3.6	4.6
Hearing aid user	3.2	3.7	5.1	-2.2	-1.5
Lung FEV1/FVC ratio	3.1	15.6	19.1	3.5	4.4
Frequency of tenseness / restlessness in last 2 weeks	3.1	4.8	5.0	2.2	2.1
Illnesses of father: Heart disease	3.1	4.2	5.5	-2.3	-1.7
Pack years of smoking	3.1	4.5	4.7	2.2	2.1
Diabetes diagnosed by doctor	3.0	4.9	5.1	-2.3	-2.2
Type 2 Diabetes (T2D) (2012)	2.9	3.4	6.7	-0.2	-2.6
Fed-up feelings	2.9	5.2	10.4	0.3	3.2
Weight	2.9	14.1	24.3	2.0	4.9
Mood swings	2.9	5.2	9.0	1.1	3.0
High cholesterol (Self-reported)	2.9	5.1	5.4	-2.2	-2.3
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	6.6	2.6	0.8
Medication: Simvastatin	2.8	4.1	5.2	-2.3	-1.7
Ever highly irritable/argumentative for 2 days	2.8	3.4	6.8	0.1	2.6
Medication: Aspirin	2.8	3.7	5.7	-1.3	-2.4
Risk taking	2.8	4.1	4.8	2.2	1.9
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	4.2	-2.0	-1.6
Alzheimer’s Disease (in mother)	2.7	3.2	6.3	2.5	0.0
Angina	2.7	3.5	6.1	-0.9	-2.5
Multivitamins +/- minerals	2.7	3.4	4.4	2.1	1.5
Body Mass Index (BMI) (2010)	2.6	3.5	4.0	1.7	2.0
Type 2 Diabetes (T2D) (2018)	2.6	4.8	6.1	-2.5	-1.9
Fractured/broken bones in last 5 years	2.6	3.4	4.3	-2.1	-1.6
Depressed Affect (Nagel 2018)	2.5	5.2	10.2	0.5	3.2
Waist Hip Ratio (WHR)	2.5	11.3	19.3	-4.4	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.5	3.8	5.5	2.3	1.4
Ever used hormone-replacement therapy (HRT)	2.4	3.1	3.8	-2.0	-1.5
Tinnitus: Yes, now most or all of the time	2.4	2.8	5.2	-0.6	-2.3
Supplements: Calcium	2.4	2.7	5.3	-0.2	-2.3
Impedance of arm (right)	2.3	10.7	14.0	-3.7	-2.7
Qualifications: A levels/AS levels or equivalent	2.3	5.2	6.6	2.6	1.9
Loud music exposure frequency	2.3	2.5	4.8	-2.2	-0.3
Gout (self-reported)	2.3	3.2	5.3	-1.1	-2.3
Chronic bronchitis/emphysema (mother)	2.3	2.7	3.2	-1.8	-1.5
Long-standing illness, disability or infirmity	2.3	3.6	4.5	-2.1	-1.6
Osteoporosis (self-reported)	2.3	2.8	2.8	-1.7	-1.7
Medication: Aspirin	2.3	3.0	3.9	-1.4	-2.0
Impedance of whole body	2.3	11.6	14.0	-3.7	-3.0
Medication: Lansoprazole	2.2	2.5	2.7	-1.5	-1.6
Leg fat mass (right)	2.2	8.5	15.7	1.1	4.0
Alzheimer’s Disease (including proxy)	2.1	3.0	5.8	2.4	-0.5
Supplements: Zinc	2.1	2.2	3.5	1.0	1.9
Angina (self-reported)	2.1	2.7	5.1	-0.6	-2.3
Illnesses of mother	2.0	2.4	4.0	0.9	2.0
Pulse wave reflection index	2.0	2.4	3.7	-1.9	-1.1
Leg fat mass (left)	2.0	7.7	14.1	1.1	3.8
Fluid intelligence score	1.9	4.0	8.0	-0.0	-2.8
Exposure to tobacco smoke at home	1.9	2.1	3.7	-1.9	-0.7
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	4.7	2.2	1.3
Medication: Amlodipine	1.9	2.7	4.6	-0.9	-2.1
Leg pain on walking	1.9	2.3	4.6	0.2	2.1
Commuting to job workplace: Cycle	1.9	2.3	4.1	2.0	0.7
Crohns Disease (2017)	1.8	4.0	6.1	-1.4	-2.5
Waist circumference	1.8	6.7	13.3	0.4	3.7
Number of live births	1.8	2.5	5.0	-2.2	-0.3
Miserableness	1.8	3.2	4.3	1.4	2.1
Age started oral contraceptive pill	1.8	2.3	4.5	-0.1	-2.1
Respiratory disease	1.7	3.7	7.4	2.7	-0.0
Frequency of depressed mood in last 2 weeks	1.7	2.4	2.4	1.5	1.6
Diabetes (father)	1.7	2.1	3.9	-2.0	-0.5
Whole body fat mass	1.7	7.1	13.9	0.5	3.7
Average weekly champagne plus white wine intake	1.7	2.3	2.6	-1.6	-1.4
Pulse rate	1.6	2.7	2.9	-1.7	-1.6
Asthma	1.6	3.2	6.1	2.5	0.6
Arm fat mass (right)	1.6	6.4	12.5	0.6	3.5
Knee pain experienced in last month	1.6	2.6	3.7	-1.2	1.9
BMI	1.5	8.8	9.9	2.8	3.1
Had menopause	1.5	1.9	2.8	-1.7	-1.0
Mouth/teeth dental problems: Dentures	1.5	2.5	5.0	-2.2	0.1
Breast cancer (self-reported)	1.5	1.8	2.0	1.2	1.4
Asthma (self-reported)	1.5	3.0	5.7	2.4	0.4
Ovarian Cancer	1.4	1.8	3.3	0.6	-1.8
HDL Cholesterol	1.4	2.3	3.8	1.9	1.0
Maternal smoking around birth	1.4	2.0	3.8	-2.0	-0.5
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.5	-0.6	1.6
Trunk fat mass	1.4	5.9	11.8	0.1	3.4
Diabetes (self-reported)	1.4	2.2	3.1	-1.7	-1.2
Number of children fathered	1.4	1.6	2.7	0.7	1.6
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	2.4	-0.9	-1.6
Medication: Seretide 50 evohaler	1.4	1.6	1.8	-1.2	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.7	1.8	-1.3	-1.3
Smoking status: Current	1.4	2.3	4.3	-0.5	2.1
Vitamin and mineral supplements	1.3	1.7	2.0	-1.4	-1.2
Current tobacco smoking	1.3	2.1	3.6	-0.8	1.9
High blood pressure (mother)	1.3	1.8	2.0	-1.4	-1.3
Impedance of leg (left)	1.3	6.4	9.8	-3.1	-1.7
Tense / ‘highly strung’	1.3	2.1	3.7	1.9	0.7
Arm fat mass (left)	1.3	5.4	10.1	0.8	3.2
Severe depression (siblings)	1.2	1.4	2.5	1.6	0.5
Impedance of leg (right)	1.2	6.0	10.3	-3.2	-1.3
Stomach or abdominal pain in last month	1.2	1.5	2.4	-1.5	0.8
Body mass index (BMI)	1.2	5.2	9.1	1.2	3.0
Blood clot in the leg (DVT)	1.2	1.6	2.5	-0.8	-1.6
Schizophrenia vs Biploar Disorder	1.1	1.5	2.8	-1.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.5	4.4	-2.1	0.8
Mouth/teeth dental problems	1.1	1.7	2.9	1.7	-0.7
Worrier / anxious feelings	1.1	2.1	2.4	1.3	1.6
Standing height	1.1	10.7	19.9	1.2	4.5
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.3	-0.5	1.5
Medication for pain relief, constipation, heartburn	1.1	1.8	1.9	1.4	1.3
Medication: Lisinopril	1.1	1.5	2.1	-0.9	-1.5
Number of operations (self-reported)	1.1	1.6	3.1	-1.8	0.4
Relative age of first facial hair	1.0	2.0	2.1	-1.4	-1.4
Age when periods started (menarche)	1.0	2.4	2.9	-1.7	-1.4
Supplements: Glucosamine	1.0	1.3	2.6	-1.6	-0.3
Chronic bronchitis/emphysema (father)	1.0	1.2	1.2	1.1	1.1
Happiness	1.0	1.2	2.0	1.4	0.7
Neck or shoulder pain in last month	1.0	1.4	1.7	-1.3	1.0
Suffer from ‘nerves’	1.0	1.5	2.8	0.5	1.7
Mother’s age at death	1.0	1.2	1.6	0.9	1.3
Alcohol drinker status: Previous	1.0	1.1	2.0	1.4	-0.4
Schizophrenia (2018)	0.9	1.9	3.9	0.2	2.0
Medication: Co-codamol	0.9	1.1	1.3	1.1	0.9
Hearing difficulty/problems with background noise	0.9	1.5	3.0	-1.7	0.0
Depression (self-reported)	0.9	1.0	1.3	0.9	1.1
Leg fat percentage (right)	0.9	3.3	6.6	-0.3	2.6
Qualifications: College or University degree	0.9	2.8	5.4	2.3	0.5
Number of full sisters	0.9	1.1	1.8	0.6	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	1.5	-1.2	-0.7
Verbal and Numeric Reasoning (VNR)	0.8	1.8	3.4	-0.5	-1.9
Crohns Disease (2012)	0.8	1.3	1.6	-1.0	-1.3
Mean Putamen Volume	0.8	0.9	1.1	-0.9	1.0
Height	0.8	15.4	30.2	0.8	5.5
Lung FVC	0.8	4.0	8.0	-0.0	-2.8
Number of incorrect matches in round	0.8	1.4	2.6	1.6	-0.4
Qualifications: None of the above	0.8	1.7	2.3	-1.0	-1.5
Pain all over the body in last month	0.8	0.9	1.5	-0.5	-1.2
Time employed in main current job	0.8	0.9	1.7	-0.4	1.3
Length of working week for main job	0.8	0.8	1.5	1.2	0.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	1.2	-0.9	-1.1
Comparative body size at age 10	0.8	2.1	4.2	0.3	-2.0
Emphysema/chronic bronchitis	0.8	0.9	1.8	-1.3	0.1
Medication: Omeprazole	0.8	1.0	1.4	-1.2	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	1.8	0.2	1.3
Commuting to job workplace: Walk	0.8	0.9	1.3	0.7	1.1
Osteoarthritis (self-reported)	0.8	1.0	1.7	-1.3	-0.7
Ever taken oral contraceptive pill	0.8	0.9	1.6	-1.2	0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.1	1.8	-1.3	-0.6
Fasting Glucose	0.7	0.8	1.5	-1.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	1.6	-1.2	1.2
Neuroticism score	0.7	1.5	2.8	0.3	1.7
Falls in the last year	0.7	0.9	1.6	-0.5	1.3
Medication: Cholesterol lowering	0.7	1.1	1.8	-1.3	-0.7
Body fat percentage	0.7	2.6	4.7	-0.7	2.2
Health satisfaction	0.7	0.9	1.6	0.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	1.8	1.3	1.1
Leg fat percentage (left)	0.7	2.7	5.2	-0.4	2.3
Ever depressed for a whole week	0.7	0.8	1.2	-0.7	1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	1.0	1.5	-0.6	-1.2
Intelligence (Savage-Jansen 2018)	0.6	1.7	2.9	-0.7	-1.7
Triglycerides	0.6	0.9	1.4	-1.2	-0.7
Tanning	0.6	7.1	11.0	-1.8	-3.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.0	-1.0	-0.7
Trunk fat percentage	0.6	2.4	3.5	-1.1	1.9
Average weekly fortified wine intake	0.6	0.8	1.5	-1.2	-0.2
Arm fat percentage (right)	0.6	2.2	4.3	-0.4	2.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	4.2	2.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	3.4	1.8	0.8
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.4	0.6	1.2
Exposure to tobacco smoke outside home	0.6	0.8	1.7	0.0	-1.3
Family relationship satisfaction	0.6	0.7	1.3	1.1	0.3
Eye problems/disorders: Cataract	0.6	0.6	0.7	-0.8	0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.8	0.3	1.3
Illnesses of father: High blood pressure	0.6	0.8	1.1	-0.7	-1.1
Irritability	0.6	1.0	1.9	-1.4	-0.2
Bipolar Disorder or Schizophrenia	0.5	1.3	1.8	0.9	1.3
Ulcerative Colitis	0.5	0.8	1.0	-0.7	-1.0
Townsend deprivation index at recruitment	0.5	0.8	1.4	-0.3	-1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.0	-0.3	1.0
Hair/balding pattern: Pattern 3	0.5	0.7	0.7	-0.8	0.8
Medication: Paracetamol	0.5	0.8	1.6	-1.2	0.2
Worry too long after embarrassment	0.5	0.8	0.9	-1.0	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.1	1.1	-0.5
Migraine (self-reported)	0.5	0.6	1.1	0.1	1.1
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.2	-1.1	0.1
Guilty feelings	0.5	0.7	1.5	1.2	0.2
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.0	-1.0	0.6
Medication: Paracetamol	0.5	0.7	1.2	-1.1	0.4
Myopia	0.5	0.7	1.1	-1.0	-0.6
Bipolar Disorder (2018)	0.4	0.7	1.3	1.1	-0.3
Neuroticism (Nagel 2018)	0.4	1.1	2.1	-0.1	1.4
Worry (Nagel 2018)	0.4	0.9	1.7	0.3	1.3
Schizophrenia (2014)	0.4	0.8	1.5	-0.1	1.2
Medication for hormone replacement therapy	0.4	0.4	0.8	-0.9	-0.2
Noisy workplace	0.4	0.5	0.6	-0.6	0.8
Chest pain or discomfort	0.4	0.5	1.0	-1.0	-0.2
Arm fat percentage (left)	0.4	1.7	3.4	-0.2	1.9
Mineral and other dietary supplements	0.4	0.5	0.6	0.8	0.6
Commuting to job workplace: Public transport	0.4	0.5	0.5	-0.7	-0.7
Alcohol drinker status: Never	0.4	0.5	0.9	0.2	1.0
Unable to work because of sickness or disability	0.4	0.5	1.0	1.0	0.1
Alzheimer’s Disease (in father)	0.3	0.4	0.8	0.9	0.1
Major Depression (MDD)	0.3	0.4	0.6	0.4	0.8
Diabetes (mother)	0.3	0.4	0.7	0.9	-0.0
Qualifications: CSEs or equivalent	0.3	0.4	0.5	-0.7	0.5
Serious illness, injury or assault to yourself	0.3	0.3	0.6	-0.3	-0.8
Alcohol usually taken with meals	0.3	0.5	0.6	-0.8	-0.6
Forced vital capacity (FVC)	0.3	1.3	2.5	1.6	-0.2
Pulse rate, automated reading	0.3	1.0	1.2	-1.0	-1.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.7	-0.9	0.1
Average weekly red wine intake	0.3	0.5	0.6	-0.6	0.8
Medication: Gliclazide	0.3	0.4	0.6	-0.3	-0.8
Average weekly beer plus cider intake	0.3	0.5	0.9	-0.1	1.0
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.6	0.0	0.8
Neuroticism (2016)	0.2	0.3	0.4	0.5	-0.6
Neuroticism	0.2	0.4	0.6	-0.5	0.8
Hair Pigment	0.2	6.9	13.6	0.4	3.7
Sensitivity / hurt feelings	0.2	0.3	0.4	0.6	-0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	0.6	-0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	-0.7	-0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	0.5	-0.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.5	-0.7	0.3
Had other major operations	0.2	0.2	0.5	0.1	0.7
Lung cancer (father)	0.2	0.2	0.4	0.6	0.2
Breastfed as a baby	0.2	0.3	0.3	0.5	0.6
Forced vital capacity (FVC), Best measure	0.2	0.7	1.5	1.2	-0.2
Age at first live birth	0.2	0.3	0.6	0.8	0.2
Overall health rating	0.2	0.5	0.8	-0.9	0.4
Supplements: Vitamin C	0.2	0.2	0.2	0.4	0.4
Illnesses of siblings: Diabetes	0.2	0.3	0.6	-0.8	-0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	-0.6	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	0.7	0.2
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	-0.3	-0.6
Heart disease (siblings)	0.2	0.3	0.5	-0.7	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.2	0.4	-0.2
Heel T-Score	0.1	0.8	0.8	-0.9	-0.9
Average weekly spirits intake	0.1	0.1	0.2	0.0	-0.5
Medication: Metformin	0.1	0.1	0.1	-0.3	0.4
Hand grip strength (right)	0.1	0.4	0.7	-0.2	-0.8
Nervous feelings	0.1	0.2	0.3	0.5	0.2
Financial difficulties in last 2 years	0.1	0.1	0.1	0.4	0.2
Prospective memory result	0.1	0.2	0.3	0.6	-0.1
Hair/balding pattern: Pattern 4	0.1	0.3	0.5	-0.1	-0.7
Peak expiratory flow (PEF)	0.1	0.1	0.1	0.4	-0.3
Glaucoma (self-reported)	0.1	0.1	0.3	-0.5	0.2
Wheeze or whistling in the chest in last year	0.1	0.1	0.2	-0.1	-0.4
Shortness of breath walking on level ground	0.1	0.1	0.2	-0.3	0.4
Eye problems/disorders: None of the above	0.1	0.1	0.1	0.3	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.0	-0.4
Alcohol intake frequency.	0.1	0.2	0.4	0.1	-0.6
Qualifications: nursing, teaching	0.1	0.2	0.3	0.3	0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.1	-0.4
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	-0.2	-0.0
Hand grip strength (left)	0.0	0.1	0.1	-0.2	-0.3
Sitting height	0.0	0.0	0.0	0.2	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	-0.3	0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	0.1	-0.2
Age at last live birth	0.0	0.0	0.0	0.0	-0.0
Ever had bowel cancer screening	0.0	0.0	0.1	0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	-0.3	-0.1
Wears glasses or contact lenses	0.0	0.0	0.0	0.1	0.0
Financial situation satisfaction	0.0	0.0	0.0	0.0	-0.2
Medication: Atorvastatin	0.0	0.0	0.0	0.0	0.1

Hub : Genes

ACAD10

Models

Trait associations