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chr10:103,550,604-105,647,095

Best TWAS P=5.21e-09 · Best GWAS P=3.63e-08 conditioned to 0.0604

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Liver	ACTR1A	0.15	0.00	lasso	10	0.00	4.6e-01	-2.80	-5.8	5.2e-09	-0.56	0.04	0.44	TRUE
3	GTEx	Adipose Visceral Omentum	NT5C2	0.13	0.07	enet	12	0.08	5.0e-05	4.23	5.6	2.6e-08	0.47	0.11	0.88	TRUE
14	The Cancer Genome Atlas	Rectum Adenocarcinoma	C10orf32	0.17	0.14	blup	52	0.14	3.2e-04	5.16	-5.7	1.2e-08	-0.77	0.01	0.82	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AS3MT	0.17	0.16	lasso	9	0.15	4.5e-18	4.79	-5.6	2.2e-08	-0.65	0.20	0.79	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	AS3MT	0.23	0.18	lasso	3	0.18	1.8e-17	5.41	-5.5	4.1e-08	-0.76	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AS3MT	0.04	0.05	enet	3	0.04	8.6e-06	5.43	-5.4	5.9e-08	-0.77	0.00	0.99	FALSE
7	GTEx	Brain Cerebellar Hemisphere	NT5C2	0.15	0.10	enet	8	0.07	9.2e-03	4.89	-5.4	6.1e-08	-0.64	0.07	0.52	FALSE
2	GTEx	Adipose Subcutaneous	NT5C2	0.09	0.05	lasso	2	0.04	6.5e-04	5.45	5.4	6.9e-08	0.47	0.03	0.97	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C10orf32	0.06	0.06	blup	54	0.08	1.2e-07	4.93	-5.4	7.0e-08	-0.73	0.06	0.94	FALSE
4	GTEx	Artery Coronary	CYP17A1-AS1	0.20	-0.01	enet	21	0.04	2.3e-02	-0.97	5.4	8.0e-08	0.38	0.05	0.33	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	AS3MT	0.34	0.38	lasso	6	0.38	4.4e-46	4.93	-5.3	1.1e-07	-0.71	0.05	0.94	FALSE
5	GTEx	Artery Tibial	NT5C2	0.06	0.04	lasso	9	0.02	1.5e-02	5.16	-5.2	1.6e-07	-0.71	0.06	0.84	FALSE
9	GTEx	Brain Cortex	CYP17A1-AS1	0.15	0.13	lasso	7	0.14	1.3e-04	4.48	5.2	1.8e-07	0.67	0.07	0.79	FALSE
8	GTEx	Brain Cerebellum	ARL3	0.20	0.09	enet	32	0.07	3.7e-03	4.48	5.2	2.3e-07	0.55	0.10	0.75	FALSE
6	GTEx	Artery Tibial	CYP17A1-AS1	0.08	0.08	lasso	8	0.06	2.8e-05	5.16	5.2	2.4e-07	0.66	0.07	0.92	FALSE