[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr2:23,453,834-25,889,403

Best TWAS P=1.49e-11 · Best GWAS P=9.13e-13 conditioned to 0.0346

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ADCY3	0.07	0.04	lasso	6	0.01	3.2e-02	-5.4	-5.4	6.8e-08	-0.13	0.03	0.97	FALSE
2	GTEx	Adipose Subcutaneous	UBXN2A	0.06	0.04	lasso	5	0.04	5.2e-04	-5.5	-5.1	2.8e-07	-0.73	0.28	0.70	FALSE
3	GTEx	Adipose Visceral Omentum	UBXN2A	0.10	0.08	enet	29	0.03	9.8e-03	-5.8	-5.8	5.4e-09	-0.67	0.07	0.91	FALSE
4	GTEx	Artery Tibial	UBXN2A	0.12	0.06	enet	24	0.09	1.5e-07	-2.9	-5.6	2.7e-08	-0.72	0.78	0.22	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	ADCY3	0.25	0.23	enet	10	0.12	9.2e-05	-5.4	6.3	2.4e-10	0.08	0.05	0.93	TRUE
6	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	-5.4	6.0	1.6e-09	0.11	0.04	0.90	FALSE
7	GTEx	Colon Transverse	UBXN2A	0.11	0.01	enet	8	0.03	8.7e-03	-5.4	-5.8	5.7e-09	-0.75	0.08	0.69	FALSE
8	GTEx	Esophagus Muscularis	NCOA1	0.11	0.01	enet	9	0.01	5.8e-02	-4.4	-5.9	2.8e-09	-0.30	0.06	0.28	FALSE
9	GTEx	Lung	UBXN2A	0.09	0.06	enet	7	0.07	6.1e-06	-3.1	-5.2	1.9e-07	-0.72	0.29	0.70	FALSE
10	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	-4.7	5.8	7.1e-09	0.15	0.04	0.96	FALSE
11	GTEx	Nerve Tibial	RP11-443B20.1	0.07	0.03	enet	6	0.02	1.1e-02	-4.7	5.2	1.5e-07	0.15	0.04	0.94	FALSE
12	GTEx	Small Intestine Terminal Ileum	UBXN2A	0.18	0.08	enet	33	0.16	2.5e-04	-5.8	-5.7	1.2e-08	-0.84	0.03	0.90	FALSE
13	GTEx	Spleen	UBXN2A	0.31	0.11	enet	19	0.17	4.1e-05	6.5	-6.8	1.5e-11	-0.80	0.03	0.93	TRUE
14	GTEx	Whole Blood	DNAJC27	0.08	0.10	lasso	1	0.10	2.2e-09	-5.3	-5.3	8.9e-08	-0.09	0.05	0.95	FALSE
15	GTEx	Whole Blood	ADCY3	0.23	0.24	enet	24	0.27	5.5e-25	-5.7	-5.5	3.1e-08	-0.12	0.02	0.98	FALSE
16	GTEx	Whole Blood	UBXN2A	0.17	0.07	lasso	8	0.09	2.1e-08	-3.1	-6.2	5.6e-10	-0.84	0.04	0.96	FALSE
17	GTEx	Whole Blood	RP11-443B20.1	0.21	0.17	enet	32	0.20	1.8e-18	-5.3	-5.2	2.4e-07	-0.13	0.03	0.97	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	ADCY3	0.17	0.26	enet	32	0.26	6.8e-33	-5.7	6.2	6.5e-10	0.13	0.03	0.97	FALSE
19	The Cancer Genome Atlas	Glioblastoma Multiforme	ADCY3	0.36	0.14	enet	7	0.13	8.9e-05	-4.6	5.3	1.2e-07	0.05	0.02	0.56	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY3	0.03	0.02	blup	81	0.02	7.1e-04	-4.8	5.8	8.0e-09	0.07	0.06	0.88	FALSE