TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1), Best measure
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chr2:36,044,351-37,567,226
Best TWAS P=2.61e-08 · Best GWAS P=6.89e-08 conditioned to 0.0419
36M
36.2M
36.4M
36.6M
36.8M
37M
37.2M
37.4M
37.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Artery Tibial
RP11-78I14.1
0.10
0.08
enet
16
0.07
4.2e-06
4.5
-5.6
2.6e-08
-0.71
0.12
0.80
TRUE
3
GTEx
Spleen
FEZ2
0.42
0.16
enet
25
0.17
3.9e-05
4.2
5.4
5.4e-08
0.66
0.04
0.88
FALSE
1
GTEx
Adipose Subcutaneous
AC007401.1
0.10
0.02
lasso
4
0.02
5.4e-03
4.5
5.2
1.5e-07
0.87
0.02
0.96
FALSE