Best TWAS P=2.61e-08 · Best GWAS P=6.89e-08 conditioned to 0.0419
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | AC007401.1 | 0.10 | 0.02 | lasso | 4 | 0.02 | 5.4e-03 | 4.5 | 5.2 | 1.5e-07 | 0.87 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-78I14.1 | 0.10 | 0.08 | enet | 16 | 0.07 | 4.2e-06 | 4.5 | -5.6 | 2.6e-08 | -0.71 | 0.12 | 0.80 | TRUE |
| 3 | GTEx | Spleen | FEZ2 | 0.42 | 0.16 | enet | 25 | 0.17 | 3.9e-05 | 4.2 | 5.4 | 5.4e-08 | 0.66 | 0.04 | 0.88 | FALSE |