[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr1:16,273,995-17,989,765

Best TWAS P=1.04e-09 · Best GWAS P=2.06e-09 conditioned to 0.315

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Liver	MST1P2	0.20	0.14	lasso	4	0.10	7.6e-04	5.7	6.1	1.0e-09	0.92	0.01	0.96	TRUE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MST1P9	0.15	0.13	enet	15	0.13	1.5e-14	-4.5	-6.0	2.6e-09	-0.79	0.05	0.95	FALSE
2	GTEx	Brain Cerebellum	MST1L	0.21	0.13	lasso	2	0.09	1.7e-03	5.7	-5.9	4.2e-09	-0.92	0.01	0.94	FALSE
13	GTEx	Testis	MST1L	0.45	0.20	enet	34	0.25	2.5e-11	-5.2	-5.8	6.9e-09	-0.82	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	ATP13A2	0.05	0.00	enet	1	0.01	1.6e-02	-5.8	5.8	8.6e-09	0.78	0.00	0.61	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MFAP2	0.17	0.22	enet	10	0.23	6.8e-26	-5.8	5.6	2.2e-08	0.84	0.00	1.00	FALSE
9	GTEx	Pituitary	MST1L	0.39	0.22	lasso	5	0.20	1.2e-05	5.6	-5.6	2.5e-08	-0.86	0.00	0.96	FALSE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	MST1P9	0.11	0.11	blup	38	0.08	1.3e-04	-5.8	-5.6	2.6e-08	-0.79	0.00	0.98	FALSE
7	GTEx	Nerve Tibial	MFAP2	0.09	0.06	lasso	3	0.07	9.7e-06	6.0	5.5	3.4e-08	0.89	0.00	1.00	FALSE
12	GTEx	Testis	CROCC	0.18	0.03	lasso	4	0.04	1.0e-02	5.7	-5.5	3.8e-08	-0.79	0.04	0.71	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	MST1P9	0.13	0.09	lasso	6	0.11	3.3e-11	5.6	-5.5	3.8e-08	-0.91	0.01	0.99	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	MST1P2	0.14	0.03	lasso	4	0.01	5.0e-02	5.6	5.5	4.9e-08	0.95	0.01	0.95	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MST1P9	0.08	0.05	blup	38	0.08	4.2e-06	5.6	-5.5	4.9e-08	-0.85	0.01	0.98	FALSE
14	GTEx	Thyroid	MST1P2	0.18	0.11	lasso	9	0.13	2.7e-10	5.6	5.4	5.1e-08	0.88	0.00	1.00	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	MST1L	0.31	0.10	lasso	6	0.14	2.2e-05	-5.2	-5.4	5.6e-08	-0.79	0.03	0.96	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MST1P9	0.04	0.02	lasso	5	0.02	1.0e-03	-5.2	-5.4	6.1e-08	-0.86	0.01	0.93	FALSE
15	GTEx	Whole Blood	MST1L	0.08	0.02	enet	12	0.04	6.3e-05	-3.4	-5.3	9.5e-08	-0.79	0.03	0.97	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	MFAP2	0.04	0.03	blup	38	0.03	6.7e-05	-4.6	5.3	9.5e-08	0.77	0.02	0.95	FALSE
1	GTEx	Artery Aorta	MFAP2	0.24	0.04	lasso	6	0.04	3.0e-03	5.6	5.3	1.0e-07	0.84	0.00	0.99	FALSE
4	GTEx	Heart Atrial Appendage	MST1P2	0.20	0.09	lasso	4	0.09	6.7e-05	-4.5	5.3	1.1e-07	0.85	0.01	0.98	FALSE
6	GTEx	Lung	MST1P2	0.20	0.10	enet	26	0.10	5.0e-08	5.6	5.2	1.7e-07	0.74	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	MFAP2	0.06	0.04	blup	38	0.05	5.2e-06	6.0	5.2	1.7e-07	0.87	0.00	1.00	FALSE
8	GTEx	Pancreas	MST1P2	0.17	0.05	enet	23	0.13	5.4e-06	5.6	5.2	1.9e-07	0.78	0.03	0.95	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	MST1P9	0.15	0.13	enet	14	0.17	6.2e-19	-5.8	-5.2	2.0e-07	-0.69	0.01	0.99	FALSE
11	GTEx	Skin Sun Exposed Lower leg	MST1L	0.34	0.20	enet	37	0.25	5.6e-21	-3.4	-5.1	2.7e-07	-0.72	0.26	0.73	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	MFAP2	0.12	0.06	blup	38	0.07	4.3e-05	-4.6	5.1	2.7e-07	0.69	0.04	0.93	FALSE