Best TWAS P=3.4e-08 · Best GWAS P=2.72e-07 conditioned to 0.0354
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | SLC22A4 | 0.07 | 0.05 | enet | 16 | 0.05 | 4.6e-05 | -4.7 | -5.5 | 3.4e-08 | 0.64 | 0.04 | 0.90 | TRUE |
| 2 | GTEx | Whole Blood | AC034220.3 | 0.08 | 0.05 | enet | 31 | 0.06 | 4.0e-06 | 3.5 | -5.4 | 8.5e-08 | 0.59 | 0.16 | 0.76 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PDLIM4 | 0.09 | 0.02 | lasso | 6 | 0.05 | 4.5e-06 | -4.1 | -5.2 | 2.0e-07 | 0.40 | 0.03 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | SLC22A5 | 0.06 | 0.03 | lasso | 4 | 0.02 | 9.3e-04 | -4.7 | -5.4 | 7.2e-08 | 0.66 | 0.00 | 0.90 | FALSE |