[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr10:74,317,852-76,323,150

Best TWAS P=5.54e-10 · Best GWAS P=8.79e-10 conditioned to 0.558

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DNAJC9-AS1 0.17 0.00 enet 50 0.02 1.9e-02 3.0 -5.7 1.4e-08 -0.06 0.05 0.04 TRUE
2 GTEx Cells Transformed fibroblasts CAMK2G 0.06 0.04 enet 10 0.06 2.2e-05 6.1 5.9 3.9e-09 0.94 0.01 0.98 FALSE
3 GTEx Esophagus Mucosa CAMK2G 0.10 0.04 lasso 3 0.06 4.0e-05 5.1 5.2 1.7e-07 0.89 0.06 0.88 FALSE
4 GTEx Prostate RP11-574K11.5 0.29 0.02 enet 43 0.00 2.4e-01 5.5 -6.1 1.1e-09 -0.47 0.02 0.39 FALSE
5 ROSMAP Brain Pre-frontal Cortex MYOZ1 0.04 0.01 blup 235 0.02 2.6e-03 -3.9 5.2 1.7e-07 0.52 0.18 0.50 FALSE
6 YFS Blood NDST2 0.10 0.09 lasso 14 0.10 5.0e-30 6.0 -6.1 1.2e-09 -0.97 0.01 0.99 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma CHCHD1 0.02 0.01 lasso 2 0.01 2.5e-03 6.1 6.1 1.1e-09 0.99 0.01 0.94 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma SEC24C 0.04 0.02 blup 29 0.03 2.6e-06 6.1 6.2 5.5e-10 0.89 0.01 0.99 TRUE
9 The Cancer Genome Atlas Lung Adenocarcinoma SEC24C 0.02 0.01 enet 4 0.01 8.5e-03 -3.9 5.4 6.8e-08 0.50 0.05 0.16 FALSE
10 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma BMS1P4 0.21 0.08 enet 15 0.08 2.3e-03 6.0 -5.6 1.6e-08 -0.88 0.00 0.81 FALSE