[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr17:78,665,405-80,866,427

Best TWAS P=1.29e-16 · Best GWAS P=2.09e-14 conditioned to 0.436

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DCXR	0.14	0.07	enet	17	0.10	3.4e-12	5.0	8.0	1.9e-15	-0.43	0.91	0.09	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LRRC45	0.09	0.10	enet	7	0.10	1.2e-11	-6.6	6.2	5.9e-10	-0.73	0.71	0.29	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MYADML2	0.52	0.43	enet	15	0.45	3.6e-60	-7.0	-7.1	1.1e-12	0.59	0.16	0.84	FALSE
4	CommonMind	Brain Pre-frontal Cortex	RAC3	0.09	0.05	enet	10	0.07	2.2e-08	6.6	6.1	1.2e-09	-0.22	0.75	0.15	FALSE
5	GTEx	Adipose Subcutaneous	LRRC45	0.23	0.06	lasso	3	0.05	1.0e-04	-6.7	7.4	1.6e-13	-0.75	0.53	0.37	FALSE
6	GTEx	Adipose Visceral Omentum	LRRC45	0.18	0.03	enet	12	0.10	9.0e-06	-6.6	5.3	1.4e-07	-0.75	0.58	0.34	FALSE
7	GTEx	Adrenal Gland	DCXR	0.38	0.18	lasso	4	0.20	1.2e-07	5.5	5.2	1.6e-07	-0.22	0.86	0.02	FALSE
8	GTEx	Artery Aorta	DCXR	0.34	0.17	enet	25	0.21	1.4e-11	5.7	6.3	2.2e-10	-0.34	0.99	0.01	FALSE
9	GTEx	Artery Tibial	LRRC45	0.09	0.07	lasso	4	0.04	2.0e-04	-6.7	7.0	1.8e-12	-0.76	0.18	0.79	FALSE
10	GTEx	Artery Tibial	DCXR	0.28	0.21	lasso	5	0.21	3.1e-16	5.7	6.2	5.2e-10	-0.19	1.00	0.00	FALSE
11	GTEx	Artery Tibial	CCDC57	0.08	0.03	enet	7	0.05	5.8e-05	-4.2	5.7	1.5e-08	-0.45	0.37	0.50	FALSE
12	GTEx	Brain Cerebellum	DCXR	0.20	0.23	lasso	3	0.22	4.5e-07	5.5	5.7	1.0e-08	-0.19	0.33	0.04	FALSE
13	GTEx	Brain Cerebellum	RP11-1055B8.4	0.25	0.27	lasso	2	0.27	1.3e-08	5.3	-5.2	2.5e-07	0.07	0.00	1.00	TRUE
14	GTEx	Cells EBV-transformed lymphocytes	DCXR	0.29	0.24	lasso	2	0.20	3.8e-07	5.0	5.3	1.0e-07	-0.15	0.82	0.02	FALSE
15	GTEx	Cells Transformed fibroblasts	LRRC45	0.08	0.08	enet	3	0.08	2.6e-06	-6.7	6.6	3.4e-11	-0.81	0.33	0.66	FALSE
16	GTEx	Esophagus Muscularis	DCXR	0.18	0.08	lasso	5	0.05	9.2e-04	5.7	7.0	1.8e-12	-0.30	0.61	0.14	FALSE
17	GTEx	Heart Atrial Appendage	LRRC45	0.19	0.06	enet	9	0.12	6.7e-06	-6.3	7.2	7.2e-13	-0.79	0.20	0.73	FALSE
18	GTEx	Nerve Tibial	DCXR	0.19	0.06	enet	20	0.10	1.4e-07	5.0	6.4	1.4e-10	-0.27	0.84	0.05	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	DCXR	0.12	0.00	enet	13	0.00	2.3e-01	5.5	7.0	1.8e-12	-0.42	0.08	0.17	FALSE
20	GTEx	Skin Sun Exposed Lower leg	DCXR	0.08	0.11	lasso	7	0.09	4.6e-08	5.5	6.3	2.8e-10	-0.23	0.99	0.00	FALSE
21	GTEx	Thyroid	ASPSCR1	0.23	0.15	enet	19	0.09	1.2e-07	-6.3	7.1	1.0e-12	-0.74	0.82	0.18	FALSE
22	GTEx	Thyroid	DCXR	0.35	0.20	lasso	5	0.30	5.1e-23	5.5	6.7	1.9e-11	-0.26	1.00	0.00	FALSE
23	YFS	Blood	ASPSCR1	0.11	0.07	lasso	9	0.06	7.9e-20	-7.6	8.1	4.3e-16	-0.85	0.00	1.00	TRUE
24	YFS	Blood	LRRC45	0.01	0.00	lasso	1	0.00	1.3e-02	5.7	5.7	1.0e-08	-0.17	0.02	0.28	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LRRC45	0.02	0.03	blup	36	0.02	1.5e-03	-6.6	6.8	7.6e-12	-0.80	0.02	0.65	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PYCR1	0.02	0.01	blup	9	0.01	1.1e-02	-7.0	7.4	1.3e-13	-0.68	0.00	0.69	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC45	0.05	0.07	lasso	6	0.06	9.5e-08	-6.6	6.1	8.2e-10	-0.81	0.10	0.90	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYADML2	0.03	0.03	blup	10	0.03	1.1e-04	-7.2	-7.2	5.1e-13	0.69	0.02	0.92	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOTUM	0.06	0.02	enet	2	0.02	4.7e-03	-6.3	-7.2	4.6e-13	0.63	0.01	0.54	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	NPB	0.03	0.01	enet	3	0.01	1.1e-02	-6.4	6.0	2.1e-09	-0.64	0.01	0.66	FALSE
31	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LRRC45	0.10	0.02	blup	35	0.04	8.0e-03	-5.0	6.7	1.7e-11	-0.76	0.01	0.41	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	STRA13	0.05	0.03	lasso	3	0.02	1.8e-03	-6.6	6.6	3.6e-11	-0.75	0.09	0.41	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	DCXR	0.09	0.03	blup	38	0.09	9.5e-09	5.5	8.3	1.3e-16	-0.49	0.26	0.73	TRUE