[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted : ← →

chr10:4,334,578-5,844,628

Best TWAS P=2.8e-09 · Best GWAS P=7.24e-08 conditioned to 0.997

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial AKR1C2 0.14 0.10 enet 10 0.15 1.2e-11 -5.4 -5.6 1.8e-08 0.94 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts AKR1C2 0.28 0.23 lasso 6 0.21 1.9e-15 -5.4 -5.4 5.6e-08 1.00 0.00 1.00 FALSE
3 GTEx Esophagus Muscularis AKR1C2 0.30 0.21 lasso 2 0.19 8.5e-12 -5.4 -5.4 6.3e-08 1.00 0.00 1.00 FALSE
4 GTEx Heart Atrial Appendage AKR1C2 0.28 0.37 lasso 3 0.29 1.2e-13 -5.4 -5.4 7.6e-08 0.98 0.00 1.00 FALSE
5 GTEx Ovary AKR1C3 0.35 0.20 lasso 9 0.22 3.9e-06 -5.4 -5.9 2.8e-09 0.91 0.01 0.96 TRUE
6 GTEx Skin Sun Exposed Lower leg AKR1C2 0.17 0.18 lasso 2 0.18 4.0e-15 -5.4 -5.4 7.3e-08 1.00 0.00 1.00 FALSE
7 GTEx Testis AKR1C2 0.44 0.36 lasso 4 0.36 8.5e-17 -5.4 -5.3 1.1e-07 1.00 0.00 1.00 FALSE
8 ROSMAP Brain Pre-frontal Cortex AKR1C2 0.56 0.40 enet 28 0.46 1.0e-65 -5.4 -5.3 1.5e-07 0.93 0.00 1.00 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AKR1C2 0.12 0.11 lasso 6 0.09 1.6e-10 -5.4 -5.5 4.7e-08 1.00 0.00 1.00 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma AKR1C2 0.29 0.21 lasso 1 0.21 4.7e-12 -5.4 -5.4 7.6e-08 0.98 0.00 1.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma AKR1C2 0.09 0.05 blup 62 0.05 3.4e-06 -5.3 -5.2 2.1e-07 0.89 0.00 1.00 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma AKR1C2 0.39 0.18 enet 14 0.23 2.5e-23 -5.4 -5.6 2.4e-08 0.85 0.00 1.00 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma AKR1C2 0.09 0.08 lasso 3 0.08 7.2e-08 -5.3 -5.4 5.8e-08 0.90 0.00 1.00 FALSE