Best TWAS P=1.26e-10 · Best GWAS P=2.18e-24 conditioned to 1.53e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RIOK3 | 0.02 | 0.01 | bslmm | 348 | 0.00 | 1.8e-01 | -4.8 | -6.4 | 1.3e-10 | 0.42 | 0.14 | 0.06 | TRUE |
| 2 | GTEx | Nerve Tibial | TMEM241 | 0.16 | 0.04 | enet | 10 | 0.07 | 1.8e-05 | -5.0 | -5.5 | 3.6e-08 | 0.43 | 0.70 | 0.03 | FALSE |
| 3 | GTEx | Testis | C18orf8 | 0.12 | 0.07 | lasso | 6 | 0.08 | 1.9e-04 | -3.2 | -5.9 | 3.7e-09 | 0.42 | 0.14 | 0.55 | FALSE |