[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted percentage : ← →

chr4:105,598,022-107,511,296

Best TWAS P=4.11e-15 · Best GWAS P=8.56e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	INTS12	0.06	0.06	enet	5	0.05	2.9e-07	7.7	-7.8	8.8e-15	-1.00	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	GSTCD	0.08	0.07	lasso	8	0.07	2.9e-06	5.7	7.0	2.7e-12	0.76	0.08	0.92	FALSE
3	GTEx	Adrenal Gland	INTS12	0.23	0.02	enet	21	0.04	1.4e-02	2.2	-6.1	1.0e-09	-0.60	0.05	0.76	FALSE
4	GTEx	Artery Aorta	INTS12	0.13	0.14	lasso	3	0.14	6.5e-08	6.3	-6.4	1.3e-10	-0.90	0.03	0.97	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	GSTCD	0.16	0.07	lasso	17	0.03	4.3e-02	6.5	6.8	9.4e-12	0.92	0.02	0.94	FALSE
6	GTEx	Cells Transformed fibroblasts	INTS12	0.15	0.16	lasso	9	0.17	9.5e-13	6.5	-7.1	1.1e-12	-0.96	0.03	0.97	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-5.8	-5.4	6.1e-08	-0.07	0.58	0.02	TRUE
8	GTEx	Esophagus Muscularis	INTS12	0.12	0.10	lasso	15	0.10	1.3e-06	7.6	-7.3	3.0e-13	-0.98	0.02	0.98	FALSE
9	GTEx	Nerve Tibial	GSTCD	0.09	0.03	enet	16	0.02	1.3e-02	6.1	6.8	1.4e-11	0.73	0.06	0.90	FALSE
10	GTEx	Pituitary	GSTCD	0.28	0.14	lasso	5	0.09	2.8e-03	6.3	6.3	3.9e-10	0.87	0.03	0.92	FALSE
11	GTEx	Skin Sun Exposed Lower leg	GSTCD	0.08	0.02	lasso	6	0.01	3.8e-02	6.3	7.1	1.4e-12	0.78	0.03	0.96	FALSE
12	GTEx	Thyroid	INTS12	0.07	0.05	lasso	7	0.03	1.2e-03	7.6	-7.7	1.9e-14	-0.99	0.02	0.97	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	INTS12	0.04	0.03	blup	51	0.04	3.9e-04	6.5	-7.2	7.5e-13	-0.92	0.01	0.96	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	INTS12	0.04	0.03	blup	49	0.04	7.1e-08	6.3	-7.5	4.5e-14	-0.93	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INTS12	0.12	0.06	blup	50	0.08	1.2e-04	7.6	-7.4	1.1e-13	-0.88	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	INTS12	0.03	0.02	blup	49	0.02	6.4e-03	7.7	-7.7	1.4e-14	-0.91	0.01	0.87	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	INTS12	0.08	0.10	lasso	2	0.10	2.9e-11	7.6	-7.6	3.6e-14	-0.98	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	INTS12	0.32	0.00	blup	49	0.06	1.8e-04	6.3	-7.2	5.3e-13	-0.73	0.01	0.80	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	GSTCD	0.07	0.05	lasso	4	0.04	6.6e-05	7.7	7.9	4.1e-15	0.99	0.02	0.98	TRUE
20	The Cancer Genome Atlas	Lung Adenocarcinoma	INTS12	0.08	0.10	enet	11	0.10	9.9e-12	7.7	-7.5	7.7e-14	-0.97	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	INTS12	0.03	0.01	blup	49	0.03	6.0e-03	4.5	-6.5	1.0e-10	-0.79	0.02	0.64	FALSE
22	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	INTS12	0.22	0.15	lasso	6	0.16	2.3e-07	6.5	-6.4	1.2e-10	-0.89	0.02	0.96	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	INTS12	0.15	0.11	lasso	3	0.17	2.1e-17	4.1	-6.2	4.1e-10	-0.78	0.05	0.95	FALSE
24	The Cancer Genome Atlas	Stomach Adenocarcinoma	GSTCD	0.04	0.06	lasso	1	0.05	9.1e-05	7.5	7.5	6.9e-14	0.95	0.02	0.94	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	INTS12	0.11	0.09	blup	49	0.11	1.3e-10	7.6	-7.3	3.6e-13	-0.89	0.01	0.99	FALSE