TWAS hub - INTS12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0560	0.0220	3.2e-04	0.062	0.026	0.055	0.045	0.054	5.3e-08	3.6e-04	2.9e-07	3.2e-06	3.4e-07
2	GTEx	Adrenal Gland	0.2252	0.0808	6.3e-04	0.019	NA	0.040	NA	0.040	6.8e-02	NA	1.4e-02	NA	1.5e-02
3	GTEx	Artery Aorta	0.1350	0.0460	3.1e-04	0.140	NA	0.084	NA	0.136	4.0e-08	NA	2.2e-05	NA	6.5e-08
4	GTEx	Cells Transformed fibroblasts	0.1450	0.0380	1.4e-08	0.159	NA	0.168	NA	0.170	6.0e-12	NA	1.3e-12	NA	9.5e-13
5	GTEx	Esophagus Muscularis	0.1160	0.0410	2.9e-04	0.104	NA	0.072	NA	0.099	7.7e-07	NA	3.7e-05	NA	1.3e-06
6	GTEx	Thyroid	0.0700	0.0300	1.2e-03	0.054	NA	0.029	NA	0.034	5.4e-05	NA	2.5e-03	NA	1.2e-03
7	METSIM	Adipose	0.0542	0.0240	4.6e-04	0.016	0.021	0.001	NA	0.005	1.4e-03	3.6e-04	2.0e-01	NA	4.6e-02
8	TCGA	Bladder Urothelial Carcinoma	0.0400	0.0230	7.6e-04	0.025	0.037	0.029	NA	0.034	3.0e-03	3.9e-04	1.5e-03	NA	7.3e-04
9	TCGA	Breast Invasive Carcinoma	0.0390	0.0186	1.7e-07	0.030	0.035	0.032	NA	0.031	6.7e-07	7.1e-08	3.4e-07	NA	4.2e-07
10	TCGA	Cervical Squamous Cell Carcinoma	0.1160	0.0600	2.6e-04	0.059	0.078	0.055	NA	0.071	7.1e-04	1.2e-04	1.1e-03	NA	2.3e-04
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0297	0.0195	4.4e-03	0.015	0.015	0.014	NA	0.008	6.8e-03	6.4e-03	8.4e-03	NA	3.4e-02
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0808	0.0338	2.6e-09	0.102	0.092	0.095	NA	0.099	1.7e-11	1.6e-10	7.2e-11	NA	2.9e-11
13	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3220	0.1390	2.5e-05	-0.002	0.063	0.045	NA	0.032	4.6e-01	1.8e-04	1.4e-03	NA	5.9e-03
14	TCGA	Lung Adenocarcinoma	0.0767	0.0335	1.5e-10	0.103	0.089	0.100	NA	0.098	5.2e-12	1.3e-10	9.9e-12	NA	1.4e-11
15	TCGA	Ovarian Serous Cystadenocarcinoma	0.0300	0.0210	6.2e-03	0.015	0.027	0.026	NA	0.018	3.2e-02	6.0e-03	6.9e-03	NA	2.0e-02
16	TCGA	Pancreatic Adenocarcinoma	0.2250	0.1070	2.4e-05	0.153	0.141	0.151	NA	0.163	5.8e-07	1.7e-06	6.8e-07	NA	2.3e-07
17	TCGA	Prostate Adenocarcinoma	0.1495	0.0680	4.8e-15	0.106	0.161	0.165	NA	0.169	3.6e-11	1.5e-16	6.2e-17	NA	2.1e-17
18	TCGA	Thyroid Carcinoma	0.1090	0.0460	2.7e-10	0.093	0.108	0.102	NA	0.105	2.7e-09	1.3e-10	3.7e-10	NA	2.0e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Lung FVC	27.7	141.1	171.6	-13.1	-8.1	-12.8	-13.0	-12.9	-12.9	-7.1	-12.3	-12.7	-12.3	-12.5	-12.8	-10.2	-12.7	-10.4	-12.5	-11.1	-12.2
Lung FEV1/FVC ratio	26.0	131.9	187.7	-11.5	-10.0	-10.3	-10.9	-10.6	-11.5	-7.6	-12.6	-12.0	-12.4	-13.2	-11.4	-13.7	-11.4	-12.1	-9.7	-11.9	-12.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	23.0	48.7	60.1	-7.8	-6.1	-6.4	-7.1	-7.3	-7.7	-3.5	-7.2	-7.5	-7.4	-7.7	-7.6	-7.2	-7.5	-6.5	-6.4	-6.2	-7.3
Forced expiratory volume in 1-second (FEV1)	22.7	76.5	94.5	-9.4	-7.5	-8.6	-9.2	-8.9	-9.2	-5.0	-8.8	-9.6	-9.6	-9.7	-9.2	-9.4	-8.9	-7.5	-8.8	-7.8	-9.1
Forced expiratory volume in 1-second (FEV1), Best measure	20.1	64.2	79.7	-8.8	-6.7	-7.7	-8.4	-8.3	-8.7	-3.9	-8.0	-8.9	-8.9	-8.9	-8.7	-8.5	-8.4	-6.7	-8.0	-6.8	-8.3
Forced vital capacity (FVC)	11.9	45.7	59.0	-7.5	-5.0	-7.1	-7.5	-7.2	-7.4	-3.8	-6.5	-7.7	-7.5	-7.3	-7.3	-6.5	-7.0	-5.0	-7.5	-5.5	-6.8
Forced vital capacity (FVC), Best measure	10.3	37.5	48.7	-7.0	-4.9	-6.1	-6.8	-6.7	-7.0	-2.6	-5.8	-7.0	-6.8	-6.6	-6.9	-5.9	-6.6	-4.5	-6.5	-4.6	-6.1
Irritability	5.6	9.5	17.6	2.3	4.0	2.8	2.6	2.6	2.3	4.2	3.5	2.8	3.0	3.0	2.4	2.8	2.6	3.7	2.3	4.0	3.4
Severe depression (siblings)	5.1	5.7	7.9	-2.2	-0.9	-2.0	-2.4	-2.3	-2.4	-2.6	-2.3	-2.8	-2.7	-2.7	-2.4	-2.6	-2.5	-2.5	-2.3	-2.1	-2.8
Asthma	5.0	9.9	14.1	3.5	2.5	3.6	3.8	3.4	3.4	0.9	3.4	3.1	3.0	3.2	3.4	2.5	3.4	2.8	3.4	3.1	3.0
Asthma (self-reported)	5.0	10.0	14.5	3.6	2.6	3.7	3.8	3.5	3.4	0.9	3.4	3.2	3.0	3.1	3.5	2.5	3.4	2.7	3.5	3.1	3.0
Peak expiratory flow (PEF)	4.7	10.9	17.0	-3.3	-3.0	-3.1	-3.3	-3.2	-3.4	-1.5	-2.9	-3.8	-4.0	-3.9	-3.5	-4.1	-3.2	-2.1	-3.6	-2.8	-3.4
Depression (self-reported)	4.6	5.6	8.2	2.5	2.0	2.1	2.4	2.5	2.5	1.4	2.1	2.9	2.8	2.7	2.5	2.9	2.3	1.6	2.5	1.6	2.5
Respiratory disease	4.4	9.8	11.7	3.4	3.1	3.3	3.4	3.2	3.2	1.4	3.3	3.2	3.2	3.3	3.4	2.9	3.2	2.8	3.1	3.2	3.1
Medication: Bendroflumethiazide	4.0	6.1	15.8	-2.4	-0.3	-2.8	-2.6	-2.4	-2.2	-4.0	-2.7	-2.5	-2.4	-2.1	-2.2	-1.6	-2.4	-2.4	-2.4	-2.8	-2.5
HbA1C	3.8	4.2	8.5	-2.2	-2.9	-1.5	-1.6	-1.7	-1.9	-1.5	-2.3	-2.0	-2.2	-2.2	-1.9	-1.7	-2.2	-2.4	-1.0	-2.4	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	3.8	5.1	8.9	2.2	1.8	2.2	2.4	2.4	2.2	1.7	2.1	2.8	3.0	2.4	2.5	2.3	2.2	1.2	2.4	1.8	2.4
Illness, injury, bereavement, stress in last 2 years	3.8	4.6	9.4	1.7	1.3	1.8	1.8	1.5	1.4	2.5	2.5	2.2	2.6	2.4	1.6	2.2	1.9	2.7	1.6	3.1	2.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.7	4.4	11.5	2.0	1.5	2.1	2.2	1.9	2.1	1.7	2.8	1.4	1.4	1.9	2.1	1.5	2.5	3.4	1.4	2.5	2.2
Medication: Ventolin 100micrograms inhaler	3.5	4.5	6.7	2.5	1.6	2.3	2.6	2.4	2.5	0.5	2.2	2.0	1.9	2.1	2.4	2.1	2.4	1.8	2.4	1.5	1.9
Mood swings	3.2	5.8	13.6	2.0	3.7	1.7	1.8	1.9	2.0	2.4	2.5	2.5	2.7	2.8	1.9	2.7	2.1	2.6	1.6	2.7	2.8
Ever had prostate specific antigen (PSA) test	3.1	3.5	12.4	-1.7	-3.5	-1.4	-1.5	-1.4	-1.5	-1.1	-2.1	-1.5	-1.7	-1.8	-1.5	-1.7	-1.9	-2.5	-1.2	-2.1	-2.1
Taking other prescription medications	2.9	4.5	7.4	2.3	1.3	2.2	2.2	2.1	2.1	0.8	1.9	2.5	2.7	2.5	2.1	2.5	2.1	1.4	2.3	1.8	2.3
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.1	8.1	1.6	0.4	2.1	1.9	1.8	1.5	2.2	1.8	2.6	2.8	2.4	1.6	2.5	1.5	1.4	2.3	2.2	2.4
Crohns Disease (2012)	2.6	4.2	5.6	2.3	1.4	2.4	2.3	2.2	2.2	1.1	2.0	2.1	1.9	2.1	2.2	1.7	2.3	1.8	2.4	1.8	2.0
Medication: Blood pressure	2.6	5.0	7.3	-2.5	-1.6	-2.7	-2.5	-2.4	-2.4	-2.6	-2.4	-2.2	-2.1	-2.0	-2.3	-1.2	-2.4	-1.7	-2.4	-2.3	-2.1
Medication: Atenolol	2.5	3.1	7.8	-1.6	0.2	-1.7	-1.8	-1.7	-1.6	-2.8	-1.9	-1.7	-1.6	-1.7	-1.6	-1.2	-1.8	-2.0	-1.6	-2.0	-2.0
Schizophrenia (2014)	2.4	5.4	7.8	-2.5	-1.1	-2.5	-2.5	-2.4	-2.5	-1.8	-2.1	-2.8	-2.7	-2.6	-2.5	-2.1	-2.4	-1.6	-2.8	-1.8	-2.4
Heart disease (mother)	2.3	2.8	4.9	-2.0	-0.7	-1.8	-1.9	-2.0	-2.2	-0.4	-1.9	-1.6	-1.2	-1.4	-2.1	-0.3	-2.2	-2.0	-1.5	-1.5	-1.7
Depression (Nagel 2018)	2.2	3.4	5.9	1.5	1.4	1.6	1.7	1.9	2.0	2.0	1.8	2.1	2.4	1.9	1.7	2.0	1.7	1.4	1.6	1.7	2.0
Body Mass Index (BMI) (2010)	2.2	3.1	4.8	1.9	2.2	1.4	1.6	1.8	1.8	1.1	1.9	1.8	1.7	1.8	1.8	1.8	1.8	2.0	1.4	1.6	1.8
Leg pain on walking	2.2	2.8	7.5	-1.4	-1.9	-1.2	-1.4	-1.3	-1.3	-1.8	-1.4	-1.6	-2.0	-2.2	-1.2	-2.7	-1.4	-1.3	-1.6	-1.5	-1.8
Had other major operations	2.1	2.6	4.2	2.1	1.6	1.7	1.8	2.1	2.0	1.2	0.9	2.0	1.7	1.6	2.0	1.3	1.7	0.2	2.0	0.3	1.2
Number of full sisters	2.1	2.6	3.9	-1.4	-1.0	-1.6	-1.6	-1.4	-1.4	-1.9	-1.5	-1.9	-2.0	-1.9	-1.4	-1.8	-1.4	-1.5	-1.7	-1.7	-1.9
Average weekly red wine intake	2.1	3.2	12.1	1.3	0.6	1.4	1.6	1.7	1.5	3.5	2.1	1.3	1.4	1.6	1.5	1.1	1.8	2.4	1.3	2.2	1.8
Chronic bronchitis/emphysema (father)	2.0	2.4	8.5	1.4	2.9	1.0	1.2	1.2	1.4	1.5	1.4	1.4	1.5	1.6	1.4	1.9	1.4	1.7	0.8	1.2	1.5
Hair/balding pattern: Pattern 3	2.0	3.0	4.7	-1.9	-2.2	-1.2	-1.5	-1.7	-1.8	-1.8	-1.8	-1.8	-1.8	-1.9	-1.8	-1.3	-1.8	-1.7	-1.2	-1.5	-1.9
Length of working week for main job	2.0	2.2	3.3	-1.7	-0.1	-1.2	-1.4	-1.6	-1.6	-1.8	-1.4	-1.8	-1.7	-1.6	-1.6	-1.5	-1.5	-1.3	-1.2	-1.0	-1.5
Bipolar Disorder or Schizophrenia	1.9	4.6	6.4	-2.3	-2.5	-2.2	-2.3	-2.2	-2.3	-0.7	-2.0	-2.4	-2.2	-2.3	-2.4	-2.0	-2.2	-1.8	-2.3	-1.6	-2.1
Ever depressed for a whole week	1.9	2.4	4.6	-1.7	-0.6	-1.9	-2.1	-1.9	-1.9	0.5	-1.5	-1.8	-1.5	-1.3	-1.9	-0.5	-1.7	-0.9	-2.0	-1.0	-1.4
Bipolar Disorder (2018)	1.8	2.8	7.5	-1.5	-2.7	-1.3	-1.4	-1.5	-1.6	-0.9	-1.6	-1.7	-1.7	-1.8	-1.6	-1.9	-1.6	-1.7	-1.3	-1.5	-1.8
Alzheimer’s Disease (in mother)	1.8	2.1	4.8	-1.2	-0.6	-2.2	-1.7	-1.3	-1.2	0.2	-1.7	-1.2	-1.1	-1.4	-1.3	-0.7	-1.4	-1.7	-1.8	-2.1	-1.5
Alzheimer’s Disease (including proxy)	1.8	2.6	5.2	-1.4	-0.9	-2.1	-1.9	-1.5	-1.5	-0.6	-1.8	-1.3	-1.3	-1.6	-1.5	-1.0	-1.6	-1.9	-2.0	-2.3	-1.6
Bipolar Disorder (2011)	1.8	1.8	3.9	-1.7	-2.0	-1.4	-1.5	-1.5	-1.5	-0.3	-1.5	-1.1	-0.9	-0.9	-1.5	0.2	-1.6	-1.4	-1.2	-1.2	-1.2
Illnesses of siblings	1.8	2.5	4.7	1.5	-0.4	1.9	1.7	1.6	1.6	1.0	1.1	2.0	2.0	1.9	1.5	1.9	1.4	0.2	2.2	1.2	1.5
Alcohol intake frequency.	1.8	4.3	7.1	2.5	2.7	2.0	2.1	2.0	2.3	1.1	1.8	2.3	2.2	2.3	2.2	1.9	2.2	1.6	1.9	1.6	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	4.5	1.5	0.9	1.6	1.8	1.8	1.6	2.1	1.2	1.5	1.3	1.1	1.6	0.4	1.5	0.5	1.8	0.9	1.1
Emphysema/chronic bronchitis	1.7	1.9	4.2	1.5	2.1	1.3	1.6	1.4	1.5	0.2	0.9	1.5	1.5	1.4	1.6	1.8	1.3	0.6	1.7	0.3	1.1
Neuroticism	1.6	3.7	7.9	1.2	2.6	1.6	1.5	1.3	1.2	2.4	1.7	2.3	2.8	2.3	1.2	2.5	1.3	1.3	1.8	2.2	2.3
Multivitamins +/- minerals	1.6	2.0	3.4	-1.2	-1.8	-1.8	-1.5	-1.3	-1.2	-1.5	-1.5	-1.4	-1.4	-1.3	-1.3	-1.4	-1.2	-1.2	-1.5	-1.5	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	9.7	0.7	2.2	0.6	0.8	0.8	0.9	3.1	1.3	1.7	2.0	1.8	0.9	2.4	0.9	1.3	0.9	1.6	1.7
Ever highly irritable/argumentative for 2 days	1.6	2.0	4.9	-1.4	-0.8	-2.0	-1.8	-1.4	-1.2	-0.0	-1.1	-1.6	-1.5	-1.4	-1.4	-1.4	-1.2	-0.4	-2.2	-1.4	-1.3
Comparative body size at age 10	1.6	4.3	12.1	1.8	1.2	1.3	1.7	1.8	2.0	2.2	1.9	2.2	2.4	2.8	1.9	3.5	2.0	2.1	1.6	1.8	2.3
Neuroticism (Nagel 2018)	1.5	3.6	8.1	1.2	2.8	1.7	1.5	1.3	1.2	2.3	1.9	2.0	2.4	2.1	1.3	1.8	1.4	1.6	1.6	2.6	2.3
Pain all over the body in last month	1.5	1.6	3.5	-1.6	-0.7	-0.5	-1.2	-1.6	-1.8	-0.6	-1.3	-1.1	-1.1	-1.5	-1.9	-1.0	-1.8	-1.6	-0.5	-0.6	-1.4
Illnesses of mother	1.5	1.8	3.1	1.7	0.5	1.4	1.5	1.6	1.7	0.8	1.2	1.4	1.3	1.4	1.8	0.8	1.7	0.8	1.5	0.8	1.3
Pulse wave reflection index	1.5	1.9	4.6	-1.4	-0.9	-2.2	-1.7	-1.4	-1.4	-0.4	-1.3	-1.4	-1.3	-1.3	-1.3	-0.6	-1.4	-0.9	-2.0	-1.3	-1.3
Ever used hormone-replacement therapy (HRT)	1.4	1.7	7.5	0.9	2.3	0.4	0.8	0.9	0.8	2.7	1.2	1.1	1.3	1.2	0.7	1.6	0.9	1.6	0.3	1.0	1.3
Family relationship satisfaction	1.4	1.8	3.8	-1.5	-1.1	-1.9	-1.6	-1.4	-1.4	-0.5	-1.3	-1.4	-1.3	-1.3	-1.4	-0.7	-1.3	-0.8	-1.8	-1.0	-1.2
Hearing aid user	1.4	1.5	2.3	1.3	0.7	1.0	1.0	1.3	1.3	1.3	1.3	1.3	1.3	1.3	1.4	1.3	1.4	1.5	0.8	1.2	1.4
Neuroticism (2016)	1.3	1.9	6.7	0.1	2.6	0.6	0.4	0.3	0.1	2.4	0.8	1.4	1.8	1.7	0.2	2.3	0.2	0.6	0.9	1.7	1.5
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	3.8	1.0	1.2	1.3	1.2	1.2	1.0	1.1	0.6	1.7	2.0	1.5	1.1	1.4	1.0	-0.2	1.8	0.6	1.4
Tense / ‘highly strung’	1.3	2.1	5.5	0.6	1.9	1.6	1.2	0.9	0.6	1.4	1.3	1.5	1.9	1.7	0.6	2.3	0.7	1.0	1.8	1.8	1.6
Guilty feelings	1.3	2.0	4.6	1.4	1.8	1.4	1.3	1.5	1.3	1.1	0.9	1.9	2.1	1.5	1.4	1.3	1.1	0.1	1.6	0.8	1.4
Ever had hysterectomy (womb removed)	1.2	1.4	7.4	-0.0	2.7	-0.3	0.1	0.0	0.1	2.1	0.8	0.8	1.2	1.2	0.0	1.7	0.5	1.4	0.0	1.4	1.4
Fed-up feelings	1.2	2.2	4.9	1.2	2.2	1.3	1.3	1.3	1.3	1.2	1.3	1.8	1.9	1.8	1.3	1.9	1.2	1.1	1.4	1.2	1.7
Blood clot in the leg (DVT)	1.2	1.5	4.4	-1.6	0.1	-1.8	-1.6	-1.5	-1.5	0.3	-0.7	-1.3	-1.1	-1.3	-1.4	-0.8	-1.2	0.1	-2.1	-0.5	-0.9
Number of full brothers	1.2	1.5	2.7	-1.1	-1.0	-1.1	-1.1	-1.1	-1.1	-1.7	-1.5	-1.2	-1.2	-1.2	-1.1	-1.3	-1.1	-1.2	-1.0	-1.6	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	4.5	-1.6	-0.1	-1.8	-1.5	-1.5	-1.4	0.1	-0.6	-1.3	-1.2	-1.4	-1.4	-0.9	-1.2	0.1	-2.1	-0.5	-1.0
Lupus	1.1	1.7	4.1	0.7	1.0	0.7	0.9	0.8	0.8	1.6	1.6	1.2	1.7	1.6	0.7	1.6	1.1	1.4	0.7	2.0	1.7
Frequency of depressed mood in last 2 weeks	1.1	1.5	4.2	0.8	1.8	0.9	1.0	1.0	0.8	2.0	1.3	1.3	1.5	1.2	1.0	1.1	1.0	1.2	0.7	1.4	1.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.1	-1.4	-1.0	-1.0	-1.2	-1.4	-1.4	-0.7	-0.9	-1.2	-1.1	-1.2	-1.4	-1.0	-1.3	-0.6	-1.2	-0.3	-0.9
Diabetes (mother)	1.1	1.4	4.3	-1.3	-2.1	-0.3	-0.8	-1.3	-1.3	-1.5	-0.9	-1.2	-1.0	-1.2	-1.3	-1.1	-1.3	-1.0	-0.5	-0.5	-1.0
High blood pressure (mother)	1.1	1.5	2.5	-1.4	-1.2	-0.8	-1.0	-1.2	-1.4	-1.0	-1.0	-1.5	-1.6	-1.5	-1.4	-1.3	-1.3	-0.6	-1.0	-1.0	-1.3
Worrier / anxious feelings	1.1	2.1	4.5	0.5	2.1	1.3	1.1	0.7	0.6	1.9	1.2	1.7	2.1	1.8	0.7	1.7	0.8	0.9	1.6	1.9	1.8
Pulse rate	1.1	1.8	3.8	1.0	0.9	1.4	1.3	1.3	1.0	0.8	1.6	1.5	1.6	1.5	1.0	0.8	1.3	1.4	1.5	1.9	1.7
Eye problems/disorders: None of the above	1.1	1.2	3.6	0.9	1.7	0.7	1.0	1.1	1.0	0.4	1.5	0.8	0.7	0.8	1.0	-0.3	1.4	1.9	0.5	1.5	1.3
Loneliness, isolation	1.1	1.6	3.4	1.0	1.8	1.5	1.3	1.2	1.1	1.1	1.3	1.3	1.3	1.0	1.2	0.3	1.2	1.2	1.3	1.5	1.4
Ever taken oral contraceptive pill	1.1	1.2	2.4	-1.1	-0.3	-0.4	-0.9	-0.9	-1.1	-0.8	-1.4	-1.2	-1.5	-1.2	-1.1	-1.2	-1.2	-1.5	-0.3	-1.1	-1.5
Ever smoked	1.1	1.9	3.7	-1.5	0.5	-1.1	-1.4	-1.3	-1.5	-0.6	-1.3	-1.7	-1.8	-1.7	-1.5	-1.9	-1.3	-1.0	-1.4	-0.9	-1.5
Depressed Affect (Nagel 2018)	1.0	2.2	4.3	1.1	1.8	1.2	1.1	1.1	1.1	1.7	1.7	1.6	1.8	1.6	1.2	1.1	1.3	1.7	1.0	2.1	1.9
Schizophrenia (2018)	1.0	2.1	3.6	-1.7	-1.0	-1.8	-1.7	-1.6	-1.8	-0.1	-1.3	-1.7	-1.4	-1.5	-1.7	-1.2	-1.6	-0.9	-1.9	-0.8	-1.3
Worry (Nagel 2018)	1.0	2.1	4.7	0.6	1.8	1.3	1.0	0.7	0.5	2.0	1.2	1.6	2.2	1.8	0.6	2.1	0.7	0.8	1.4	2.0	1.7
Verbal and Numeric Reasoning (VNR)	1.0	2.4	7.5	1.4	1.9	1.9	1.5	1.6	1.3	2.7	1.4	1.4	1.3	1.3	1.3	1.7	1.1	1.0	1.7	1.5	1.2
Number of live births	1.0	1.4	3.8	-0.6	-0.6	-1.6	-1.4	-1.0	-0.7	-1.1	-1.7	-0.9	-0.9	-1.0	-0.8	-0.4	-1.0	-1.4	-1.4	-2.0	-1.2
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.5	-0.5	-0.7	-0.9	-0.8	-0.5	-0.3	-1.5	-1.2	-1.1	-1.6	-1.3	-0.5	-1.2	-0.6	-1.0	-0.8	-1.9	-1.6
Exposure to tobacco smoke at home	1.0	1.2	2.9	-1.2	-0.6	-1.7	-1.5	-1.3	-1.1	0.1	-0.9	-1.1	-1.0	-0.9	-1.2	-1.2	-0.9	-0.4	-1.7	-0.6	-0.6
Medication: Amlodipine	1.0	1.4	4.4	-1.0	-1.8	-0.3	-0.3	-0.7	-0.9	-2.1	-1.1	-1.0	-1.2	-1.4	-0.7	-1.7	-0.9	-1.4	-0.2	-1.4	-1.3
Medication for pain relief, constipation, heartburn	1.0	1.6	2.7	1.3	0.3	1.5	1.6	1.5	1.4	1.2	1.5	1.1	1.0	1.1	1.3	0.9	1.5	1.4	1.5	1.2	1.0
Medication: Allopurinol	1.0	1.3	2.2	1.3	0.2	1.1	1.1	1.4	1.4	1.5	0.7	1.4	1.3	1.3	1.4	1.1	1.2	0.4	1.2	0.3	1.1
Chest pain or discomfort	1.0	1.5	3.5	1.1	0.3	1.1	1.1	1.2	1.0	1.2	1.1	1.3	1.5	1.5	1.1	1.9	1.1	1.0	1.1	1.3	1.3
Medication: Lisinopril	1.0	1.3	2.6	0.7	1.3	1.1	1.1	1.0	0.9	1.1	1.4	1.0	1.0	1.1	1.1	0.9	1.1	1.6	0.9	1.4	1.2
Breast Cancer	0.9	2.2	5.0	1.3	0.6	1.0	1.2	1.1	1.4	0.9	1.7	1.5	1.6	1.7	1.4	1.6	1.6	2.2	0.8	1.9	1.9
Average weekly spirits intake	0.9	1.1	2.7	-1.1	-1.6	-1.3	-1.1	-0.9	-1.0	-0.8	-1.0	-0.9	-0.8	-1.0	-0.8	-0.6	-1.0	-1.2	-1.1	-1.1	-1.1
Neuroticism score	0.9	1.9	4.4	0.5	1.8	1.2	0.9	0.8	0.6	2.0	1.1	1.7	2.1	1.6	0.7	2.0	0.7	0.7	1.4	1.7	1.6
Birth weight of first child	0.9	1.7	5.4	-0.9	-2.3	-0.3	-0.9	-0.7	-1.2	0.8	-1.4	-1.1	-1.4	-1.6	-1.1	-1.8	-1.3	-1.6	-0.5	-1.2	-1.5
Headache pain in last month	0.9	1.5	2.3	1.4	0.6	1.3	1.2	1.2	1.2	1.3	1.1	1.5	1.5	1.3	1.3	0.8	1.2	0.9	1.2	1.3	1.5
Number of children fathered	0.9	1.0	3.0	-0.8	-0.8	-1.1	-1.1	-0.8	-0.7	-0.7	-1.1	-1.0	-1.2	-1.0	-0.8	-1.7	-0.7	-0.9	-1.1	-1.1	-0.9
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.9	0.7	1.1	0.9	0.9	0.7	0.9	0.4	1.4	0.8	0.8	1.0	0.8	0.4	1.2	1.7	0.5	1.6	1.2
Medication: Aspirin	0.9	1.2	2.0	-1.2	-1.3	-1.4	-1.2	-1.1	-1.0	-1.0	-1.2	-0.9	-0.8	-0.9	-1.0	-0.8	-1.0	-1.1	-1.2	-1.1	-0.9
Miserableness	0.9	1.6	4.9	0.7	1.9	0.5	0.6	0.6	0.6	2.2	1.2	1.2	1.6	1.4	0.7	1.6	0.8	1.4	0.4	1.6	1.6
Ovarian Cancer	0.8	1.0	2.1	-1.2	-1.4	-1.3	-1.1	-1.0	-0.9	0.6	-0.9	-1.0	-0.9	-0.9	-1.0	-0.6	-0.9	-0.5	-1.3	-1.1	-0.9
Relative age voice broke	0.8	1.2	2.7	-1.2	-1.5	-0.9	-0.9	-1.0	-1.2	-1.0	-1.2	-1.0	-0.8	-0.9	-1.1	-0.5	-1.3	-1.6	-0.5	-1.3	-1.2
Impedance of arm (right)	0.8	3.5	5.5	1.9	1.2	2.2	2.2	1.8	1.8	0.2	2.3	1.6	1.7	1.8	1.8	1.4	2.1	2.2	2.0	2.2	2.1
Father’s age at death	0.8	1.0	2.4	-1.3	-1.6	-1.2	-1.1	-1.0	-1.0	1.5	-1.0	-0.6	-0.4	-0.5	-0.9	0.8	-1.1	-0.7	-0.9	-1.0	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	2.7	1.2	0.7	1.3	1.2	1.1	1.1	0.6	0.8	1.6	1.6	1.4	1.0	1.4	0.9	0.1	1.6	0.8	1.1
Falls in the last year	0.8	1.0	4.0	0.7	1.9	1.0	0.9	0.9	0.7	2.0	0.3	1.1	1.2	0.7	0.7	1.2	0.4	-0.4	1.3	0.2	0.5
Loud music exposure frequency	0.8	0.9	1.7	-0.5	-1.3	-0.8	-0.8	-0.5	-0.6	-0.0	-0.8	-1.1	-1.3	-1.3	-0.6	-1.2	-0.8	-0.8	-1.0	-1.2	-1.2
Wheeze or whistling in the chest in last year	0.8	1.4	1.9	1.4	0.4	1.3	1.3	1.2	1.2	0.0	1.4	1.3	1.3	1.3	1.2	1.3	1.2	1.0	1.2	1.3	1.2
Medication: Ibuprofen	0.8	1.0	1.9	1.0	1.1	1.1	0.9	0.8	0.8	0.3	1.0	1.1	1.1	1.1	0.7	1.2	0.7	0.9	1.0	1.4	1.2
Medication: Seretide 50 evohaler	0.8	0.9	1.6	1.2	-0.0	1.2	1.2	1.1	1.1	-0.6	1.1	0.7	0.5	0.7	1.0	0.5	1.2	1.2	1.1	0.8	0.8
Hypertension (Self-reported)	0.8	2.1	7.4	-1.3	-0.8	-1.4	-1.3	-1.3	-1.4	-2.7	-1.6	-1.2	-1.2	-1.4	-1.3	-1.0	-1.5	-1.8	-1.1	-1.5	-1.6
Medication: Atorvastatin	0.8	1.0	3.1	-0.8	-1.7	-1.1	-0.9	-0.6	-0.6	-0.2	-1.5	-0.5	-0.4	-0.6	-0.5	-0.3	-0.8	-1.8	-0.6	-1.7	-1.0
Myopia	0.8	1.2	1.8	-1.2	-1.0	-0.9	-1.0	-1.0	-1.2	-0.6	-1.0	-1.2	-1.2	-1.3	-1.3	-0.9	-1.3	-1.1	-0.8	-0.8	-1.3
Intelligence (Savage-Jansen 2018)	0.7	2.0	10.9	1.0	1.2	2.0	1.4	1.5	1.0	3.3	1.0	1.3	1.1	1.0	1.2	1.3	0.9	0.4	1.8	1.1	0.8
Reaction Time	0.7	1.4	4.8	0.6	1.5	0.5	0.3	0.6	0.7	2.0	1.4	0.8	1.0	1.3	0.7	0.9	1.0	1.7	0.1	2.2	1.4
Fasting Glucose	0.7	0.8	3.6	0.6	0.2	0.7	0.3	0.3	0.4	1.5	1.2	0.7	0.9	0.8	0.3	0.9	0.5	1.4	0.3	1.9	1.0
LDL Cholesterol	0.7	1.2	3.7	-0.7	-1.9	-1.3	-1.1	-0.6	-0.6	-0.4	-1.3	-0.9	-0.9	-0.9	-0.7	-1.1	-0.9	-1.5	-1.1	-1.4	-1.1
Hypothyroidism (self reported)	0.7	1.7	2.6	1.6	1.0	1.2	1.5	1.6	1.5	0.7	1.4	1.3	1.2	1.1	1.6	0.4	1.6	1.4	1.0	1.2	1.5
Relative age of first facial hair	0.7	1.4	2.6	-1.5	-1.5	-1.4	-1.4	-1.3	-1.6	0.8	-1.2	-0.9	-0.5	-0.7	-1.4	0.5	-1.6	-1.3	-1.0	-0.9	-1.0
Pack years adult smoking proportion	0.7	1.0	2.2	1.3	0.2	1.5	1.4	1.2	1.2	-0.2	1.2	0.9	0.8	0.8	1.1	0.3	1.2	1.0	1.1	1.0	0.8
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.5	0.9	0.9	0.2	0.3	0.7	0.8	1.1	1.0	0.7	0.8	1.1	0.7	1.3	0.9	1.6	-0.1	0.9	1.1
Heart attack	0.7	0.9	2.7	0.8	-0.4	0.2	0.6	1.0	1.0	1.6	0.4	1.2	1.4	1.2	1.0	1.6	0.8	0.0	0.5	0.0	0.8
Medication: Lansoprazole	0.7	0.8	1.6	-1.2	0.5	-1.1	-1.2	-1.2	-1.2	0.2	-0.7	-0.6	-0.4	-0.5	-1.3	0.3	-1.2	-0.5	-1.1	-0.4	-0.6
Mouth/teeth dental problems: Loose teeth	0.7	0.8	7.1	-0.3	-2.7	-0.5	-0.4	-0.3	-0.3	-0.9	-0.8	-0.6	-0.8	-0.7	-0.3	-0.3	-0.6	-0.8	-0.3	-1.2	-1.0
Mean time to correctly identify matches	0.7	1.3	5.1	0.5	1.4	0.3	0.2	0.5	0.5	2.3	1.1	1.0	1.3	1.3	0.5	1.4	0.7	1.2	0.2	1.9	1.3
Friendships satisfaction	0.7	0.9	2.4	-1.0	-0.1	-1.4	-1.2	-1.1	-1.1	1.5	-0.6	-0.9	-0.6	-0.6	-1.1	-0.1	-0.8	0.1	-1.4	-0.3	-0.4
Breast cancer (self-reported)	0.7	0.9	3.1	-0.4	-1.4	-0.9	-0.8	-0.5	-0.5	-1.0	-1.2	-0.6	-0.5	-0.8	-0.5	-0.6	-0.7	-1.8	-0.6	-1.5	-1.2
Supplements: Fish oil (including cod liver oil)	0.7	0.9	3.6	-0.3	-1.9	-0.3	-0.6	-0.5	-0.5	-0.8	-0.6	-1.3	-1.6	-1.3	-0.5	-1.1	-0.6	-0.1	-0.9	-0.9	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	4.0	0.4	-0.2	0.5	0.6	0.4	0.4	2.0	0.7	1.1	1.4	1.1	0.6	1.8	0.5	0.6	0.8	0.7	1.1
Coronary Artery Disease (CAD)	0.6	0.7	1.6	1.2	1.1	0.9	1.1	1.3	1.2	-1.1	0.9	0.6	0.2	0.0	0.9	-0.1	0.9	0.6	0.7	0.0	0.0
Blood Platelet Count	0.6	7.0	17.4	-2.7	-2.5	-2.8	-2.8	-2.7	-2.6	1.0	-1.7	-3.3	-3.2	-3.0	-2.8	-4.2	-2.1	-0.5	-3.5	-1.2	-2.3
Cardiovascular Disease	0.6	2.1	6.5	-1.3	-0.5	-1.3	-1.4	-1.3	-1.4	-2.5	-1.5	-1.4	-1.3	-1.4	-1.4	-1.3	-1.4	-1.6	-1.3	-1.2	-1.4
Past tobacco smoking	0.6	1.0	3.0	1.0	-1.7	0.8	1.1	1.0	1.0	0.2	0.5	1.3	1.3	1.2	1.0	1.4	0.8	-0.0	1.3	0.2	0.9
Diabetes (self-reported)	0.6	1.0	2.2	0.8	0.3	1.3	1.1	0.8	0.8	0.7	1.3	1.0	1.0	0.7	0.8	0.2	1.0	1.1	1.1	1.5	1.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	1.9	-0.9	0.0	-0.7	-0.7	-0.8	-0.7	-1.4	-0.2	-1.2	-1.3	-1.0	-0.8	-0.8	-0.6	0.4	-1.2	-0.2	-0.8
Weight	0.6	3.1	5.6	-1.2	-0.9	-1.9	-1.9	-1.2	-1.2	-1.5	-2.1	-1.8	-2.0	-2.0	-1.3	-2.0	-1.5	-2.0	-2.0	-2.4	-2.1
Hip circumference	0.6	2.6	5.1	-1.0	0.0	-1.8	-1.7	-1.3	-1.2	-1.5	-2.0	-1.6	-1.7	-1.8	-1.2	-1.4	-1.5	-1.8	-1.8	-2.3	-1.9
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.0	-1.0	-2.0	-0.7	-0.9	-0.7	-0.8	1.2	-1.0	-1.2	-1.3	-1.3	-0.9	-1.7	-0.7	-1.0	-0.8	-1.1	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.4	1.1	1.2	1.0	0.7	0.7	0.8	0.3	0.8	0.9	0.8	0.9	0.7	0.8	0.7	0.8	0.7	1.1	1.0
Impedance of arm (left)	0.6	2.8	4.2	1.8	0.7	2.0	1.9	1.7	1.7	-0.2	2.0	1.4	1.3	1.6	1.6	1.4	1.9	2.0	1.8	1.9	1.7
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.4	0.5	2.1	0.4	0.6	0.5	0.6	1.5	0.9	0.6	0.6	1.0	0.6	1.0	0.8	1.3	0.5	0.9	1.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.0	1.0	0.9	0.9	0.9	0.9	1.0	0.2	0.9	0.7	0.6	0.6	0.8	-0.1	1.0	1.0	0.6	0.7	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.6	-0.9	-0.5	-0.3	-0.8	-0.9	-1.1	-0.3	-1.2	-0.5	-0.4	-0.7	-1.1	0.2	-1.3	-1.3	-0.2	-1.2	-0.8
Smoking status: Previous	0.6	1.0	3.5	-0.9	1.9	-0.8	-1.1	-0.9	-0.9	0.5	-0.1	-1.2	-1.1	-1.1	-0.8	-1.2	-0.5	0.6	-1.6	0.1	-0.5
Commuting to job workplace: Walk	0.6	0.7	1.2	-0.7	0.2	-1.1	-1.0	-0.8	-0.9	0.6	-1.1	-0.7	-0.5	-0.8	-0.9	-0.7	-0.8	-1.0	-0.9	-0.9	-0.6
Eye problems/disorders: Cataract	0.6	0.7	3.7	-0.4	-1.4	-0.3	-0.5	-0.4	-0.3	-0.5	-1.2	-0.1	-0.1	-0.4	-0.3	0.2	-0.7	-1.9	0.1	-1.5	-0.9
Medication for cholesterol	0.6	1.0	1.7	1.0	1.3	1.1	0.9	0.9	1.0	1.0	0.8	1.1	1.1	1.0	0.9	0.9	0.9	0.5	1.2	0.8	1.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	4.0	-0.5	-1.0	-0.7	-0.5	-0.5	-0.4	-1.2	-1.2	-0.2	-0.3	-0.7	-0.2	-0.9	-0.7	-2.0	-0.1	-1.4	-1.0
Alcohol drinker status: Never	0.6	0.7	2.3	0.6	0.9	0.4	0.6	0.4	0.7	1.1	0.7	0.9	1.0	1.2	0.6	1.5	0.7	0.9	0.5	0.8	1.0
Heart disease (siblings)	0.6	0.7	2.1	-0.7	-0.4	-1.1	-1.0	-0.8	-0.7	-0.7	-0.3	-1.1	-1.2	-1.0	-0.7	-0.7	-0.6	0.5	-1.4	-0.4	-0.8
Pack years of smoking	0.6	0.9	1.7	1.2	0.2	1.3	1.3	1.2	1.1	-0.2	1.1	0.9	0.9	0.9	1.1	0.4	1.1	1.0	1.0	0.8	0.9
Leg fat mass (left)	0.6	2.5	4.4	-1.1	-1.2	-1.8	-1.7	-1.2	-1.2	-1.7	-1.9	-1.4	-1.6	-1.7	-1.1	-1.4	-1.4	-1.9	-1.8	-2.1	-1.8
Ulcerative Colitis (UC)	0.5	0.9	3.6	-1.0	-0.3	-1.3	-1.4	-1.4	-1.0	0.1	-0.1	-1.1	-1.0	-0.7	-1.1	-0.1	-0.8	1.0	-1.9	0.1	-0.4
Mean Putamen Volume	0.5	0.5	1.8	-0.2	-0.8	-0.8	-0.5	-0.2	-0.4	-1.2	-0.9	-0.5	-0.5	-0.7	-0.3	-0.2	-0.6	-1.1	-0.4	-1.3	-0.9
Ulcerative Colitis	0.5	0.7	5.1	0.6	-0.1	0.3	0.2	0.2	0.5	0.5	1.3	0.1	0.1	0.4	0.4	-0.1	0.9	2.3	-0.5	1.6	0.9
BMI	0.5	2.8	5.1	-1.3	-0.1	-2.0	-1.8	-1.4	-1.3	-1.7	-2.1	-1.5	-1.6	-1.8	-1.3	-1.6	-1.5	-2.2	-1.8	-2.3	-1.8
Chronotype (morning person)	0.5	1.2	3.4	0.9	1.9	1.0	1.1	0.9	0.9	0.7	1.1	1.0	1.1	1.2	1.0	0.9	1.1	1.4	1.0	1.1	1.3
Supplements: Zinc	0.5	0.6	2.3	0.9	0.4	1.5	1.1	1.0	0.8	-0.9	0.7	0.3	0.1	0.1	0.8	-0.5	0.8	0.2	1.2	0.5	0.1
Diabetes (father)	0.5	0.6	1.7	-0.8	-0.2	-0.7	-0.7	-0.8	-0.6	-0.8	-1.1	-0.6	-0.7	-0.8	-0.6	-0.0	-0.9	-1.3	-0.5	-1.2	-1.1
Supplements: Glucosamine	0.5	0.7	2.2	-0.9	-0.3	-1.0	-1.2	-0.9	-0.9	0.5	-0.3	-0.9	-0.8	-0.7	-1.0	-0.3	-0.7	0.6	-1.5	-0.1	-0.4
Waist circumference	0.5	1.8	3.6	-0.7	-0.3	-1.5	-1.3	-0.9	-0.9	-1.9	-1.6	-1.2	-1.4	-1.6	-0.9	-1.4	-1.1	-1.7	-1.4	-1.9	-1.6
Mouth/teeth dental problems	0.5	0.8	1.4	0.8	-0.4	1.0	1.0	1.0	0.9	-0.9	1.2	0.8	0.7	0.6	1.0	-0.3	1.2	1.0	0.9	1.1	0.9
Trunk fat-free mass	0.5	2.6	5.2	-1.3	-0.8	-1.7	-1.8	-1.1	-1.3	0.1	-1.7	-1.9	-2.1	-2.0	-1.4	-2.3	-1.4	-1.3	-2.0	-1.6	-1.9
Glaucoma (self-reported)	0.5	0.6	1.6	-0.7	0.2	-0.5	-0.5	-0.7	-0.9	-1.3	-0.9	-0.7	-0.6	-0.8	-0.8	-0.1	-0.9	-1.1	-0.3	-1.0	-1.0
Gout (self-reported)	0.5	0.7	1.3	1.1	-0.1	0.9	0.9	1.0	1.1	0.7	0.5	1.1	1.0	1.0	1.0	0.6	1.0	0.2	1.0	0.4	0.9
Arm fat-free mass (right)	0.5	2.5	4.2	-1.3	-1.0	-1.7	-1.8	-1.1	-1.3	-0.2	-1.7	-1.8	-2.0	-1.9	-1.4	-2.1	-1.4	-1.3	-1.9	-1.6	-1.9
Health satisfaction	0.5	0.6	1.4	-0.9	-0.8	-1.0	-1.1	-1.1	-1.1	0.1	-0.4	-0.7	-0.5	-0.6	-1.2	-0.9	-0.8	-0.0	-1.1	0.4	-0.2
Medication: Omeprazole	0.5	0.6	3.7	0.1	-0.5	0.3	0.3	0.1	0.1	1.9	0.3	0.8	1.1	0.8	0.4	1.5	0.3	0.3	0.7	0.5	0.9
Leg fat mass (right)	0.5	2.0	3.5	-0.9	-1.1	-1.6	-1.5	-1.1	-1.0	-1.8	-1.7	-1.3	-1.4	-1.5	-1.0	-1.4	-1.2	-1.7	-1.6	-1.9	-1.6
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.1	-0.8	-0.8	-0.8	-0.9	-0.8	-0.9	-1.1	-0.7	-0.8	-0.7	-0.8	-0.8	-0.8	-0.8	-0.5	-1.0	-0.5	-0.7
Long-standing illness, disability or infirmity	0.5	0.7	1.5	0.9	-0.5	0.9	1.1	1.1	1.0	0.3	0.6	1.1	1.1	0.8	1.0	0.6	0.8	-0.3	1.2	0.3	0.6
Illnesses of father: High blood pressure	0.5	0.6	1.4	-0.7	-0.7	-0.3	-0.6	-0.8	-0.9	-0.8	-0.5	-1.2	-1.1	-0.9	-1.0	-1.2	-0.6	0.0	-0.7	-0.3	-0.6
Fractured/broken bones in last 5 years	0.5	0.7	1.3	1.1	0.6	1.0	1.0	1.1	1.0	0.3	0.6	0.8	0.8	0.7	1.0	1.0	0.8	0.2	1.0	0.1	0.4
Major Depression (MDD)	0.4	0.4	2.1	-0.3	1.4	-0.9	-0.7	-0.2	-0.2	1.5	-0.4	0.5	0.8	0.6	-0.3	0.7	-0.1	-0.5	-0.3	-0.3	0.4
High blood pressure	0.4	1.1	3.9	-1.0	-0.6	-1.1	-1.0	-0.9	-1.0	-2.0	-1.2	-0.7	-0.7	-0.9	-0.9	-0.3	-1.1	-1.3	-0.8	-1.1	-1.1
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.8	-0.7	-0.4	-1.1	-1.0	-1.0	-0.7	-1.7	-0.5	-1.2	-1.3	-1.0	-0.9	-0.7	-0.8	-0.1	-1.4	-0.4	-1.1
Body mass index (BMI)	0.4	1.9	4.8	-0.8	-0.3	-1.7	-1.4	-1.0	-0.8	-1.7	-1.8	-1.0	-1.1	-1.4	-0.8	-1.0	-1.2	-2.0	-1.5	-2.2	-1.5
Trunk fat mass	0.4	1.8	3.1	-0.8	-0.9	-1.3	-1.4	-1.0	-0.9	-1.8	-1.6	-1.3	-1.4	-1.5	-0.9	-1.3	-1.1	-1.6	-1.4	-1.7	-1.6
Happiness	0.4	0.4	1.0	-0.5	-0.2	-0.7	-0.7	-0.6	-0.6	-0.7	-0.7	-0.8	-0.7	-0.7	-0.7	-1.0	-0.5	-0.5	-0.7	-0.5	-0.6
Trunk predicted mass	0.4	2.1	4.5	-1.1	-0.6	-1.6	-1.6	-0.9	-1.1	0.2	-1.5	-1.7	-1.9	-1.8	-1.2	-2.1	-1.2	-1.1	-1.9	-1.5	-1.7
High blood pressure (siblings)	0.4	0.6	1.2	-0.9	0.7	-0.7	-0.8	-0.8	-1.0	-0.4	-0.7	-1.0	-1.0	-0.9	-0.9	-1.1	-0.8	-0.3	-0.8	-0.4	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.9	-0.8	0.9	-0.5	-0.6	-0.9	-0.8	-0.9	-0.7	-0.8	-0.7	-0.5	-0.9	0.0	-0.8	-0.4	-0.5	-0.5	-0.6
Neck or shoulder pain in last month	0.4	0.6	1.2	0.9	-0.7	0.8	0.8	1.0	1.1	-0.4	0.2	0.9	0.8	0.8	1.1	0.5	0.8	-0.7	1.0	-0.2	0.4
Medication: Blood pressure	0.4	0.8	4.2	-0.5	-2.1	-0.1	-0.3	-0.3	-0.5	-1.8	-0.6	-0.6	-0.6	-0.9	-0.4	-1.0	-0.6	-1.1	-0.1	-0.7	-1.0
Whole body fat mass	0.4	1.7	3.3	-0.7	-0.9	-1.3	-1.3	-0.9	-0.8	-1.8	-1.6	-1.1	-1.3	-1.4	-0.8	-1.3	-1.0	-1.7	-1.3	-1.8	-1.5
Arm predicted mass (right)	0.4	1.8	3.4	-1.1	-0.7	-1.5	-1.6	-0.9	-1.1	0.0	-1.4	-1.6	-1.8	-1.7	-1.1	-1.8	-1.2	-1.0	-1.7	-1.3	-1.7
Supplements: Vitamin C	0.4	0.5	3.0	0.7	1.1	0.7	0.7	0.6	0.7	-1.7	0.1	0.5	0.3	0.3	0.7	-0.5	0.5	-0.3	0.8	0.2	0.2
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	-0.7	0.8	-0.9	-0.7	-0.6	-0.6	0.6	-1.0	-0.2	-0.1	-0.2	-0.5	0.8	-0.9	-0.9	-0.5	-1.1	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.7	-0.3	-0.8	-0.4	-0.3	-0.3	-0.3	-0.3	-0.9	-0.4	-0.4	-0.6	-0.4	-0.7	-0.5	-1.3	-0.2	-1.0	-0.8
Mineral and other dietary supplements	0.4	0.6	1.5	0.6	1.0	0.2	0.7	0.7	0.7	0.6	0.4	1.1	1.2	1.1	0.7	0.8	0.7	0.0	0.8	0.4	1.0
Osteoarthritis (self-reported)	0.4	0.5	1.4	0.2	-0.9	0.7	0.6	0.5	0.3	1.2	-0.1	0.9	1.0	0.7	0.5	1.0	0.2	-0.5	1.2	-0.4	0.4
Medication: Aspirin	0.4	0.5	1.4	-0.7	-0.6	-1.2	-0.9	-0.7	-0.6	-0.6	-0.9	-0.5	-0.5	-0.5	-0.6	-0.5	-0.6	-0.9	-0.9	-0.9	-0.5
Basal metabolic rate	0.4	2.1	4.5	-0.9	-0.5	-1.4	-1.5	-0.8	-1.0	-0.5	-1.6	-1.6	-2.0	-1.8	-1.1	-2.1	-1.1	-1.4	-1.7	-1.7	-1.8
Leg fat percentage (left)	0.4	1.4	2.6	-0.9	-1.0	-1.6	-1.4	-1.2	-1.0	-1.5	-1.4	-1.0	-0.9	-1.0	-0.8	-0.6	-1.1	-1.3	-1.5	-1.5	-1.1
Arm fat-free mass (left)	0.4	1.9	3.5	-1.0	-0.4	-1.6	-1.6	-1.0	-1.1	-0.1	-1.4	-1.6	-1.8	-1.7	-1.1	-1.9	-1.2	-1.1	-1.8	-1.5	-1.6
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.9	0.4	-0.6	-0.2	0.2	0.6	0.6	1.3	0.1	0.8	1.0	0.9	0.7	1.4	0.4	-0.3	0.3	-0.4	0.4
Alcohol drinker status: Previous	0.4	0.5	4.1	0.2	0.4	-0.4	-0.1	0.0	0.3	2.0	0.2	0.7	1.0	0.8	0.2	1.2	0.2	0.4	-0.2	0.2	0.7
Arm predicted mass (left)	0.4	2.0	3.8	-1.1	-0.2	-1.7	-1.7	-1.0	-1.1	-0.0	-1.5	-1.6	-1.8	-1.7	-1.2	-1.8	-1.2	-1.1	-2.0	-1.5	-1.6
Age at First Birth	0.3	0.4	2.2	0.7	1.0	0.3	0.4	0.5	0.4	0.4	0.3	0.7	0.6	0.8	0.5	1.5	0.1	0.3	0.6	0.3	0.5
HDL Cholesterol	0.3	0.5	1.0	0.6	0.2	1.0	0.9	0.6	0.7	-0.6	0.8	0.8	0.8	0.7	0.8	0.3	0.8	0.5	0.9	0.8	0.8
Blood White Count	0.3	2.3	4.1	-1.1	0.3	-1.7	-1.8	-1.6	-1.4	-1.8	-1.3	-1.7	-1.7	-1.7	-1.6	-1.6	-1.4	-0.9	-2.0	-1.2	-1.6
Heel T-Score	0.3	2.5	15.2	1.2	2.5	1.1	1.2	1.6	1.2	3.9	1.2	1.3	1.3	1.2	1.3	1.1	1.3	1.2	1.0	1.0	1.3
Height	0.3	6.2	12.5	-2.3	-2.0	-1.9	-2.3	-1.6	-2.2	0.2	-2.1	-3.2	-3.5	-3.3	-2.4	-3.3	-2.4	-1.7	-2.6	-2.3	-3.2
Allergy or Eczema	0.3	0.8	2.4	-0.9	-0.1	-1.1	-1.2	-1.2	-0.9	-1.0	-0.4	-1.1	-1.1	-0.8	-1.1	-0.2	-0.9	0.2	-1.5	0.1	-0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	0.8	0.2	0.5	0.8	0.9	0.8	0.9	0.2	0.7	0.6	0.5	0.8	0.5	0.6	-0.4	0.9	-0.1	0.2
Angina	0.3	0.4	1.7	-0.6	-1.3	-0.9	-0.6	-0.4	-0.2	-0.3	-0.7	-0.5	-0.6	-0.5	-0.3	-0.3	-0.4	-0.4	-0.8	-1.2	-0.5
Medication for hormone replacement therapy	0.3	0.3	0.9	0.7	-0.9	0.8	0.9	0.7	0.6	0.4	0.5	0.5	0.4	0.2	0.5	-0.2	0.5	0.2	0.8	0.1	0.2
Vitamin and mineral supplements	0.3	0.3	1.6	0.4	1.3	0.8	0.6	0.5	0.4	0.7	0.7	0.4	0.4	0.3	0.4	0.5	0.5	0.6	0.5	0.5	0.4
Medication: Co-codamol	0.3	0.4	1.8	0.3	0.2	-0.1	0.3	0.3	0.5	-0.1	0.4	0.7	0.9	1.0	0.4	1.3	0.5	0.5	0.3	0.2	0.7
Medication: Metformin	0.3	0.5	2.1	0.1	-0.2	0.8	0.5	0.3	0.2	1.0	0.9	0.3	0.5	0.4	0.1	-0.7	0.6	0.9	0.5	1.4	0.9
Leg fat-free mass (left)	0.3	1.4	4.0	-0.5	-0.3	-1.0	-1.0	-0.5	-0.6	-0.8	-1.3	-1.3	-1.7	-1.6	-0.8	-2.0	-0.8	-1.2	-1.3	-1.6	-1.6
Average weekly fortified wine intake	0.3	0.3	0.9	-0.5	-0.3	-0.7	-0.7	-0.6	-0.5	-0.1	-0.2	-0.9	-0.9	-0.5	-0.6	-0.3	-0.4	0.1	-0.9	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.0	0.4	-1.4	0.9	0.5	0.4	0.1	-0.3	0.1	-0.2	-0.3	-0.6	0.2	-1.0	0.1	-0.2	0.5	-0.1	-0.3
Sitting height	0.3	2.1	7.1	-1.2	-1.4	-0.7	-1.2	-0.8	-1.1	-0.2	-1.3	-1.7	-2.0	-1.8	-1.3	-2.7	-1.2	-1.4	-1.0	-1.2	-1.8
Leg predicted mass (left)	0.3	1.4	3.8	-0.5	-0.2	-1.0	-1.0	-0.5	-0.6	-0.8	-1.3	-1.3	-1.7	-1.6	-0.8	-2.0	-0.8	-1.2	-1.3	-1.6	-1.6
Alcohol usually taken with meals	0.3	0.5	1.0	-0.8	-0.1	-0.8	-0.6	-0.5	-0.7	0.8	-0.3	-1.0	-0.9	-1.0	-0.9	-0.9	-0.5	-0.1	-0.8	-0.3	-0.8
Nervous feelings	0.3	0.6	1.5	-1.2	0.6	-0.8	-0.8	-1.1	-1.2	0.9	-0.2	-0.1	0.6	0.3	-1.1	1.1	-1.0	-0.3	-0.5	0.5	0.2
Medication: Simvastatin	0.3	0.4	2.6	-0.5	-0.9	-0.2	-0.3	-0.4	-0.4	-1.6	-0.5	-0.4	-0.5	-0.7	-0.5	-0.9	-0.6	-0.7	-0.2	-0.3	-0.7
Alcohol intake versus 10 years previously	0.3	0.5	1.8	0.9	0.5	0.9	0.8	0.8	0.8	-1.4	0.3	0.3	-0.1	-0.1	0.8	-1.1	0.8	0.1	0.7	-0.1	0.1
Mouth/teeth dental problems: Dentures	0.3	0.4	1.3	-0.5	1.1	-0.5	-0.6	-0.8	-0.7	0.6	-0.8	-0.1	0.1	0.2	-0.8	1.1	-0.9	-0.8	-0.2	-0.3	-0.2
Prospective memory result	0.3	0.3	1.6	-0.2	-0.5	0.0	-0.3	-0.4	-0.3	-1.2	-0.7	-0.2	-0.3	-0.3	-0.4	-0.1	-0.7	-1.0	0.2	-0.7	-0.7
Arm fat mass (right)	0.3	1.4	3.2	-0.5	-0.4	-1.4	-1.2	-0.8	-0.6	-1.7	-1.5	-1.0	-1.1	-1.2	-0.6	-1.2	-0.9	-1.6	-1.4	-1.8	-1.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.3	-0.7	-0.6	-0.4	-0.7	-0.6	-0.6	1.5	-0.5	-0.5	-0.5	-0.5	-0.7	-0.4	-0.7	-0.4	-0.6	-0.2	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.6	1.2	1.3	0.7	0.9	1.1	1.0	0.4	0.7	0.7	0.5	0.5	1.2	-0.1	1.0	0.6	0.5	0.4	0.7
Body fat percentage	0.3	1.0	4.3	-0.4	-0.7	-1.1	-0.9	-0.7	-0.5	-2.1	-1.2	-0.8	-0.8	-0.9	-0.4	-0.7	-0.7	-1.3	-1.0	-1.4	-1.0
Leg fat percentage (right)	0.3	1.1	2.6	-0.7	-0.8	-1.4	-1.2	-1.0	-0.8	-1.6	-1.2	-0.7	-0.7	-0.8	-0.6	-0.5	-0.9	-1.2	-1.3	-1.3	-0.9
Exposure to tobacco smoke outside home	0.3	0.3	1.2	0.1	-0.2	0.1	0.3	0.3	0.3	0.1	-0.2	0.9	1.0	1.0	0.4	1.1	0.2	-0.6	0.9	-0.1	0.7
Qualifications: College or University degree	0.3	0.8	5.2	0.6	-0.9	1.2	1.1	1.1	0.8	2.3	0.3	0.6	0.3	0.4	0.8	-0.1	0.7	-0.3	1.4	0.1	0.3
Had major operations	0.3	0.4	1.0	-0.8	-0.1	-0.3	-0.5	-0.7	-0.8	-0.5	-0.8	-0.5	-0.2	-0.5	-0.8	-0.1	-0.8	-1.0	-0.2	-0.7	-0.5
Age at last live birth	0.3	0.4	3.3	0.2	-1.2	0.5	0.2	0.3	0.3	-1.8	-0.0	-0.3	-0.8	-0.6	0.3	-0.8	0.2	-0.1	0.3	-0.4	-0.6
Whole body fat-free mass	0.3	1.7	4.2	-0.8	-0.5	-1.3	-1.3	-0.7	-0.8	-0.1	-1.4	-1.5	-1.8	-1.6	-1.0	-2.0	-1.0	-1.2	-1.6	-1.5	-1.6
Diabetes diagnosed by doctor	0.3	0.5	1.7	0.4	-0.4	1.0	0.8	0.6	0.6	0.4	1.1	0.6	0.6	0.4	0.6	-0.2	0.8	1.0	0.6	1.3	0.8
Medication: Gliclazide	0.3	0.3	1.9	0.4	-1.4	0.6	0.6	0.3	0.4	-0.7	0.1	0.0	-0.1	-0.4	0.4	-1.1	0.4	-0.3	0.5	-0.2	-0.1
Whole body water mass	0.3	1.9	4.2	-0.9	-0.5	-1.4	-1.4	-0.8	-0.9	-0.1	-1.5	-1.6	-1.9	-1.7	-1.1	-2.1	-1.1	-1.2	-1.7	-1.6	-1.7
Arm fat mass (left)	0.3	1.3	3.0	-0.5	-0.3	-1.3	-1.2	-0.7	-0.6	-1.7	-1.5	-0.9	-1.1	-1.2	-0.6	-1.0	-0.8	-1.5	-1.3	-1.7	-1.3
Mother’s age at death	0.3	0.4	0.7	-0.7	-0.4	-0.4	-0.7	-0.8	-0.8	-0.8	-0.6	-0.7	-0.6	-0.6	-0.8	0.0	-0.7	-0.2	-0.7	-0.1	-0.6
Commuting to job workplace: Public transport	0.3	0.3	1.9	0.1	-0.2	-0.0	0.1	0.2	-0.0	-0.1	-0.7	0.1	0.0	-0.5	-0.0	-0.1	-0.4	-1.4	0.5	-1.3	-0.7
Average weekly beer plus cider intake	0.3	0.4	2.1	-0.3	1.1	-0.5	-0.5	-0.3	-0.3	1.5	0.3	0.0	0.3	0.6	-0.3	0.8	-0.0	1.0	-0.6	0.7	0.8
Risk taking	0.3	0.4	2.9	0.1	0.9	-0.4	-0.1	0.4	0.3	1.7	0.6	-0.2	-0.1	0.2	0.3	-0.1	0.6	1.1	-0.8	0.4	0.4
Diastolic blood pressure, automated reading	0.3	0.8	2.0	-0.9	-0.2	-1.2	-1.1	-1.2	-1.1	-1.4	-0.8	-0.8	-0.5	-0.5	-1.2	-0.4	-1.1	-0.7	-1.0	-0.3	-0.6
Supplements: Calcium	0.3	0.3	1.1	0.3	0.5	0.8	0.4	0.3	0.1	-0.3	-0.2	0.5	0.7	0.4	0.2	0.8	-0.1	-1.0	1.1	0.0	0.1
Impedance of whole body	0.3	1.7	3.7	1.1	0.3	1.6	1.4	1.1	1.1	-0.1	1.8	1.0	1.0	1.3	1.1	1.1	1.4	1.9	1.3	1.8	1.5
Alzheimer’s Disease (in father)	0.2	0.2	0.5	-0.4	-0.3	-0.5	-0.7	-0.6	-0.6	0.0	-0.3	-0.3	-0.1	-0.2	-0.6	0.3	-0.6	-0.2	-0.7	-0.1	-0.1
Irritable Bowel Disease (IBD)	0.2	0.4	1.6	-0.5	0.4	-0.7	-0.8	-0.8	-0.5	0.4	0.2	-0.6	-0.5	-0.2	-0.6	0.3	-0.2	1.3	-1.2	0.5	0.1
Prostate Cancer	0.2	0.3	2.5	-0.6	1.6	-0.4	-0.3	-0.7	-0.6	0.4	0.2	-0.1	0.4	0.1	-0.6	0.5	-0.3	0.5	-0.6	0.7	0.3
Waist Hip Ratio (WHR)	0.2	1.1	6.6	-0.4	-2.6	-0.1	-0.2	-0.2	-0.4	-1.8	-0.7	-0.7	-1.0	-1.2	-0.4	-1.5	-0.5	-1.1	-0.1	-0.8	-1.1
Systolic Blood Pressure	0.2	1.2	12.5	-0.8	-0.6	-0.8	-0.7	-0.9	-0.8	-3.5	-0.7	-1.0	-0.9	-0.7	-0.8	-0.9	-0.7	-0.6	-0.7	-0.3	-0.8
Smoking Status	0.2	0.4	0.8	-0.8	0.7	-0.2	-0.4	-0.5	-0.7	-0.7	-0.4	-0.8	-0.8	-0.7	-0.7	-0.9	-0.5	-0.0	-0.4	-0.2	-0.5
Number of treatments/medications taken	0.2	0.4	1.2	0.6	-0.2	0.6	0.7	0.5	0.5	-1.1	0.3	0.7	0.9	0.8	0.5	0.9	0.4	-0.1	0.9	0.4	0.6
Hearing difficulty/problems: Yes	0.2	0.3	0.8	0.7	-0.5	0.9	0.6	0.7	0.6	0.9	0.3	0.6	0.5	0.4	0.6	-0.1	0.4	-0.3	0.8	0.2	0.3
Trunk fat percentage	0.2	0.9	4.1	-0.3	-0.5	-0.9	-0.8	-0.6	-0.4	-2.0	-1.1	-0.8	-0.9	-0.9	-0.4	-0.7	-0.6	-1.2	-0.9	-1.4	-1.0
Townsend deprivation index at recruitment	0.2	0.3	0.7	0.5	0.6	0.2	0.1	0.4	0.4	-0.4	0.5	0.5	0.6	0.7	0.5	0.9	0.3	0.4	0.0	0.8	0.6
Maternal smoking around birth	0.2	0.2	0.5	0.4	0.7	0.3	0.5	0.6	0.6	0.6	0.4	0.5	0.4	0.4	0.7	-0.1	0.6	0.2	0.3	0.3	0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.6	-0.1	1.2	-0.2	0.1	-0.1	-0.1	-1.0	0.2	-0.2	-0.3	-0.3	-0.2	-0.7	0.1	0.3	-0.3	0.3	-0.1
Qualifications: CSEs or equivalent	0.2	0.3	4.2	0.1	2.0	0.0	-0.1	-0.2	0.1	-0.3	0.0	0.1	0.1	0.3	0.1	0.4	0.1	0.4	-0.2	0.2	0.3
Stomach or abdominal pain in last month	0.2	0.2	1.0	-0.2	-0.2	-0.1	-0.1	-0.1	-0.2	1.0	-0.5	0.5	0.6	0.2	-0.1	0.4	-0.4	-1.0	0.5	-0.5	0.1
Medication: Ramipril	0.2	0.3	0.9	0.6	-1.0	0.3	0.4	0.6	0.5	0.6	0.1	0.7	0.6	0.4	0.4	0.6	0.3	-0.1	0.5	-0.1	0.3
Fluid intelligence score	0.2	0.5	3.2	0.5	0.2	0.6	0.6	0.8	0.5	1.8	0.1	0.5	0.3	0.2	0.7	0.9	0.3	-0.4	0.9	-0.3	-0.1
Noisy workplace	0.2	0.2	1.9	0.5	0.7	0.2	0.2	0.3	0.4	-0.6	0.3	-0.1	-0.3	-0.3	0.5	-1.4	0.5	0.2	-0.2	-0.0	0.1
Medication: Cholesterol lowering	0.2	0.4	2.0	-0.2	-1.4	-0.2	-0.3	-0.1	-0.2	-1.1	-0.7	-0.1	-0.2	-0.4	-0.2	-0.1	-0.5	-1.1	-0.1	-0.8	-0.7
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	-0.6	-0.3	-0.6	-0.4	-0.4	-0.5	0.6	0.1	-0.3	-0.2	-0.3	-0.5	-0.5	-0.3	0.5	-0.7	0.4	0.1
Standing height	0.2	2.0	5.5	-1.1	-1.5	-0.8	-1.3	-0.7	-1.1	0.1	-1.1	-1.9	-2.3	-1.9	-1.3	-2.4	-1.1	-0.7	-1.4	-0.9	-1.8
Hair/balding pattern: Pattern 4	0.2	0.5	3.2	-0.2	0.3	-0.1	-0.3	-0.4	-0.2	-1.8	-0.4	-0.5	-0.8	-0.7	-0.5	-1.4	-0.4	-0.4	-0.4	-0.5	-0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.1	0.2	0.7	0.1	0.0	0.3	0.1	-0.1	-0.5	-0.4	-0.6	-0.7	0.0	-0.7	-0.2	-0.8	0.0	-1.1	-0.9
Birth weight	0.2	0.3	1.7	0.5	-0.7	0.4	0.5	0.7	0.4	1.3	0.7	0.1	0.1	0.3	0.6	0.4	0.5	0.9	0.1	0.6	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.0	0.4	0.5	0.5	0.5	0.5	0.3	0.4	0.2	0.5	0.6	0.4	0.4	1.0	0.3	-0.1	0.8	0.0	0.3
Age at first live birth	0.2	0.3	1.7	-0.1	-1.3	0.5	0.4	0.2	0.2	-1.1	-0.1	-0.3	-0.7	-0.5	0.3	-0.8	0.1	-0.2	0.5	-0.4	-0.6
Pulse wave peak to peak time	0.2	0.2	0.6	0.6	0.2	0.7	0.5	0.4	0.5	-0.7	-0.2	0.2	0.2	0.3	0.5	0.4	0.3	-0.6	0.8	-0.4	-0.1
Angina (self-reported)	0.2	0.3	1.4	-0.4	-1.2	-0.8	-0.5	-0.2	-0.1	-0.0	-0.7	-0.3	-0.4	-0.3	-0.2	0.0	-0.3	-0.4	-0.7	-1.1	-0.4
Migraine (self-reported)	0.2	0.3	1.4	-0.1	-1.2	-0.8	-0.5	-0.3	-0.0	-0.8	-0.4	-0.4	-0.6	-0.4	-0.2	-0.3	-0.2	-0.2	-0.7	-0.7	-0.6
Suffer from ‘nerves’	0.2	0.3	1.1	0.2	1.0	0.4	0.3	0.2	0.1	0.9	0.3	0.6	1.1	0.6	0.1	0.9	0.2	-0.1	0.5	0.5	0.7
Knee pain experienced in last month	0.2	0.3	1.4	0.5	-0.8	-0.3	0.0	0.3	0.5	-0.7	-0.4	0.3	0.3	0.0	0.6	0.2	0.1	-0.9	-0.1	-1.2	-0.4
Illnesses of siblings: Diabetes	0.2	0.3	0.6	-0.6	0.8	-0.5	-0.4	-0.6	-0.7	0.4	0.0	-0.7	-0.6	-0.5	-0.7	-0.6	-0.3	0.5	-0.6	0.2	-0.2
Leg fat-free mass (right)	0.2	1.3	3.6	-0.4	-0.3	-0.9	-0.9	-0.4	-0.5	-0.6	-1.3	-1.3	-1.7	-1.5	-0.7	-1.9	-0.7	-1.1	-1.2	-1.5	-1.5
Ever had bowel cancer screening	0.2	0.2	0.7	0.1	0.3	0.1	0.2	0.2	0.2	0.2	-0.3	0.6	0.7	0.4	0.2	0.7	-0.1	-0.8	0.6	-0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	2.2	-0.3	0.8	-0.1	-0.3	-0.5	-0.4	1.5	0.3	0.0	0.2	0.1	-0.5	0.1	-0.3	0.6	-0.4	0.7	0.4
Back pain experienced in last month	0.2	0.3	0.8	0.5	0.7	-0.2	0.3	0.6	0.7	0.1	0.1	0.8	0.9	0.8	0.7	0.7	0.6	-0.4	0.4	-0.2	0.5
Illnesses of father: None of the above (group 1)	0.2	0.2	1.1	-0.1	-0.5	0.3	0.3	0.1	-0.1	-0.5	-0.5	-0.0	-0.2	-0.3	-0.1	-0.8	-0.2	-1.1	0.7	-0.5	-0.4
Leg predicted mass (right)	0.2	1.2	3.4	-0.4	-0.2	-0.8	-0.9	-0.4	-0.5	-0.6	-1.2	-1.2	-1.6	-1.5	-0.6	-1.8	-0.7	-1.1	-1.1	-1.5	-1.5
Average weekly champagne plus white wine intake	0.2	0.3	2.6	-0.1	0.1	0.3	0.3	0.3	0.1	1.6	0.4	0.3	0.5	0.3	0.1	0.8	0.1	0.2	0.3	0.5	0.2
Wears glasses or contact lenses	0.2	0.2	1.0	-0.2	0.1	-0.5	-0.5	-0.2	-0.3	0.2	-0.6	0.0	0.2	-0.2	-0.2	0.4	-0.6	-1.0	-0.4	-0.6	-0.5
Financial situation satisfaction	0.2	0.3	0.8	-0.7	-0.1	-0.3	-0.5	-0.6	-0.7	-0.7	-0.7	-0.2	-0.2	-0.4	-0.7	-0.7	-0.6	-0.9	-0.1	-0.2	-0.2
High cholesterol (Self-reported)	0.2	0.3	1.6	-0.3	-0.2	-0.6	-0.6	-0.2	-0.3	-0.2	-0.8	-0.1	-0.1	-0.4	-0.2	-0.2	-0.6	-1.3	-0.4	-1.0	-0.6
Medication: Paracetamol	0.2	0.4	2.3	-0.4	0.7	-0.5	-0.5	-0.5	-0.5	-0.4	-0.8	0.1	0.2	-0.2	-0.4	-0.2	-0.7	-1.5	-0.0	-0.7	-0.4
Number of operations (self-reported)	0.2	0.4	2.3	0.0	0.2	-0.1	-0.0	0.0	-0.0	0.3	-1.0	0.1	0.0	-0.2	-0.2	0.5	-0.4	-1.5	0.4	-1.3	-0.6
Age started oral contraceptive pill	0.2	0.2	0.7	0.4	0.8	0.2	0.2	0.2	0.2	0.6	-0.1	0.8	0.8	0.6	0.2	0.8	-0.0	-0.4	0.5	0.1	0.4
Commuting to job workplace: Cycle	0.2	0.2	1.6	0.2	-0.1	-0.4	-0.4	0.1	0.1	-0.3	-0.8	-0.1	-0.2	-0.1	-0.0	0.4	-0.3	-1.0	-0.1	-1.3	-0.5
Schizophrenia vs Biploar Disorder	0.1	0.2	1.2	0.2	1.1	0.4	0.3	0.0	0.1	-1.0	0.1	-0.2	-0.5	-0.3	0.0	-0.3	-0.1	0.0	0.2	0.0	-0.3
Crohns Disease (2017)	0.1	0.2	1.0	0.4	0.9	0.3	0.4	0.3	0.4	0.3	0.4	0.3	0.2	0.4	0.3	0.6	0.6	1.0	0.2	0.4	0.5
Primary Biliary Cirrhosis	0.1	0.1	0.4	0.5	0.5	-0.0	0.2	0.3	0.5	-0.4	0.1	0.3	0.2	0.3	0.4	0.6	0.3	0.2	-0.1	-0.1	0.1
Rheumatoid Arthritis	0.1	0.2	0.7	0.5	0.2	0.8	0.7	0.6	0.5	-0.5	0.2	0.1	-0.2	-0.1	0.5	-0.2	0.3	-0.0	0.7	-0.2	-0.1
Triglycerides	0.1	0.2	0.7	0.1	-0.3	-0.5	-0.4	-0.1	0.1	-0.8	-0.3	-0.2	-0.4	-0.3	-0.0	-0.4	-0.2	-0.4	-0.5	-0.6	-0.5
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.4	-0.4	-0.1	-0.3	-0.3	-0.3	-0.4	-0.1	-0.3	-0.5	-0.6	-0.6	-0.4	-0.6	-0.4	-0.2	-0.4	-0.4	-0.5
Blood Eosinophil Count	0.1	0.5	1.4	0.9	1.2	0.7	0.8	0.9	0.8	-0.1	0.7	0.6	0.4	0.1	0.7	-0.8	0.9	0.5	0.5	0.7	0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.5	0.1	-0.2	0.6	0.4	0.2	0.3	0.4	0.5	0.2	0.2	0.1	0.1	-0.5	0.3	0.4	0.4	0.7	0.3
Hand grip strength (left)	0.1	0.2	0.7	-0.4	-0.2	-0.3	-0.6	-0.6	-0.5	-0.0	0.0	-0.6	-0.4	-0.3	-0.6	-0.7	-0.4	0.5	-0.8	0.5	-0.1
Sensitivity / hurt feelings	0.1	0.2	0.6	-0.5	0.8	0.2	0.2	-0.2	-0.2	-0.2	0.2	0.3	0.5	0.4	-0.2	0.2	0.0	0.2	0.4	0.7	0.6
Systolic blood pressure, automated reading	0.1	0.3	2.5	-0.4	0.2	-0.8	-0.6	-0.7	-0.5	-1.6	-0.2	-0.2	0.1	0.0	-0.5	0.4	-0.4	-0.0	-0.7	0.1	-0.0
Impedance of leg (right)	0.1	0.5	1.8	0.2	-0.3	0.8	0.6	0.4	0.4	-0.1	1.1	0.5	0.6	0.8	0.5	0.7	0.6	1.2	0.7	1.3	0.9
Hand grip strength (right)	0.1	0.1	0.6	0.1	-0.5	-0.1	-0.1	0.1	0.3	-0.8	0.4	-0.3	-0.3	-0.1	0.1	-0.6	0.3	0.7	-0.6	0.2	-0.0
Current tobacco smoking	0.1	0.2	0.6	0.3	-0.2	0.5	0.5	0.6	0.3	-0.6	0.1	0.5	0.4	0.4	0.2	0.3	0.2	-0.3	0.8	0.1	0.2
Age when periods started (menarche)	0.1	0.1	1.7	-0.0	1.3	-0.1	-0.3	-0.2	-0.3	-0.2	-0.1	-0.3	-0.2	-0.2	-0.3	-0.4	-0.1	0.0	-0.5	0.2	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	2.4	0.8	0.8	0.4	0.6	0.7	0.5	1.6	0.3	-0.0	-0.1	-0.2	0.6	-0.4	0.5	0.4	0.1	-0.3	0.1
Serious illness, injury or assault to yourself	0.1	0.1	0.7	0.3	0.9	0.1	0.2	0.4	0.4	-0.3	0.1	0.2	0.2	0.4	0.4	0.6	0.3	-0.3	0.2	-0.2	-0.0
Impedance of leg (left)	0.1	0.4	1.4	0.1	-0.6	0.6	0.5	0.2	0.2	0.1	1.0	0.3	0.5	0.7	0.3	0.7	0.4	1.1	0.6	1.2	0.7
Number of incorrect matches in round	0.1	0.2	1.4	-0.1	-1.2	-0.3	-0.3	-0.3	-0.2	-1.2	-0.4	-0.2	-0.1	-0.0	-0.2	0.4	-0.2	-0.3	-0.4	-0.4	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	1.4	-0.0	1.2	-0.2	-0.2	-0.2	-0.0	0.1	-0.2	0.1	0.4	0.2	-0.0	0.3	-0.0	-0.4	-0.2	-0.1	0.1
Had menopause	0.1	0.1	0.7	-0.1	-0.1	-0.1	-0.0	-0.1	-0.0	0.1	0.5	0.3	0.5	0.2	0.0	0.1	0.3	0.8	-0.2	0.7	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	2.8	0.6	0.6	0.3	0.4	0.6	0.4	1.7	0.2	0.1	0.0	-0.1	0.4	-0.3	0.3	0.1	0.1	-0.1	0.1
Qualifications: None of the above	0.1	0.2	1.3	-0.0	-0.1	-0.7	-0.2	-0.2	-0.0	-1.1	0.3	0.0	0.2	0.3	0.1	1.1	0.0	0.8	-0.6	-0.1	0.2
Financial difficulties in last 2 years	0.1	0.1	0.3	0.6	0.2	0.4	0.3	0.6	0.5	0.2	-0.1	0.4	0.2	0.1	0.4	-0.2	0.2	-0.5	0.5	-0.2	-0.0
Allergy	0.1	0.3	3.0	-0.4	-0.6	-0.0	-0.3	-0.1	-0.4	1.7	-0.6	0.2	0.4	0.1	-0.3	0.2	-0.3	-0.9	0.4	-0.5	0.1
Arm fat percentage (right)	0.1	0.5	2.9	0.1	-0.1	-0.7	-0.5	-0.2	-0.0	-1.7	-0.9	-0.2	-0.3	-0.5	0.0	-0.4	-0.2	-1.2	-0.6	-1.2	-0.6
Time employed in main current job	0.1	0.1	0.3	0.1	-0.2	0.5	0.4	0.2	0.0	-0.3	0.1	0.0	-0.0	-0.1	0.0	-0.5	0.2	0.1	0.4	-0.1	0.2
Lung cancer (father)	0.1	0.2	0.8	0.2	0.9	0.0	0.3	0.4	0.3	0.8	0.3	0.4	0.3	0.2	0.4	-0.2	0.4	0.3	0.1	0.3	0.4
Breastfed as a baby	0.1	0.1	1.0	0.0	0.1	-0.1	0.0	0.2	-0.0	0.3	0.2	0.0	0.1	-0.2	0.1	-1.0	0.1	-0.2	-0.0	0.3	0.1
Medication: Paracetamol	0.1	0.2	1.1	0.0	0.9	-0.2	-0.2	-0.1	0.0	-0.6	-0.4	0.2	0.2	-0.2	-0.0	-0.5	-0.2	-1.0	0.0	-0.5	-0.2
Worry too long after embarrassment	0.1	0.1	0.5	-0.5	0.5	0.2	-0.2	-0.1	-0.5	0.7	-0.1	-0.0	0.1	-0.4	-0.3	-0.7	-0.4	-0.4	-0.0	0.2	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.6	-0.2	0.4	-0.1	-0.1	-0.3	-0.2	-0.8	-0.1	-0.3	-0.1	-0.2	-0.2	-0.5	-0.1	-0.2	-0.2	-0.1	-0.1
Pulse rate, automated reading	0.1	0.2	1.1	0.1	-1.1	0.8	0.5	0.2	-0.0	-0.5	0.5	-0.0	-0.0	0.1	0.0	-0.4	0.2	0.5	0.6	0.9	0.3
Comparative height size at age 10	0.1	0.3	1.0	0.9	-0.8	0.5	0.4	1.0	0.9	-0.2	0.5	-0.1	-0.6	-0.1	0.8	-0.3	0.7	0.9	0.1	0.0	-0.2
Overall health rating	0.1	0.3	0.6	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	0.8	-0.4	-0.1	0.2	-0.1	-0.7	0.4	-0.7	-0.6	-0.5	-0.0	-0.2
Illnesses of father: Heart disease	0.1	0.1	0.4	-0.2	0.5	-0.5	-0.3	-0.1	-0.0	0.2	0.1	-0.4	-0.4	-0.2	0.0	-0.4	0.1	0.5	-0.6	0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	-0.5	-1.0	0.0	-0.2	-0.3	-0.4	0.3	-0.1	-0.5	-0.7	-0.4	-0.5	-0.6	-0.2	0.4	-0.2	0.4	-0.2
Arm fat percentage (left)	0.1	0.5	3.2	0.1	-0.2	-0.7	-0.5	-0.2	-0.0	-1.8	-0.9	-0.3	-0.4	-0.5	0.0	-0.3	-0.3	-1.1	-0.6	-1.2	-0.6
Qualifications: nursing, teaching	0.1	0.2	1.6	0.0	-1.3	0.2	0.1	0.3	0.1	1.1	-0.1	-0.0	-0.1	-0.2	0.1	-0.3	0.2	-0.1	0.1	-0.2	-0.1
Osteoporosis (self-reported)	0.1	0.2	1.2	0.1	0.0	0.2	0.1	0.2	0.0	-0.4	-0.4	0.1	0.0	-0.2	-0.0	0.3	-0.3	-1.1	0.4	-0.8	-0.6
Smoking status: Current	0.1	0.1	0.9	-0.1	-0.3	0.2	0.1	0.1	-0.1	-1.0	-0.2	-0.0	-0.1	-0.1	-0.2	-0.1	-0.2	-0.4	0.4	-0.1	-0.2
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.7	-0.1	-0.2	0.3	0.4	0.1	0.1	-0.9	0.5	0.2	0.4	0.3	0.2	-0.1	0.3	0.4	0.4	0.7	0.5
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.4	0.0	-0.1	-0.1	-0.4	-0.5	-0.6	-0.2	-0.3	-0.2	-0.3	-0.3	0.3	-0.5	-0.3	-0.0	-0.3	-0.3
Unable to work because of sickness or disability	0.1	0.1	0.7	-0.2	-0.8	-0.3	-0.2	-0.2	-0.2	-0.8	-0.3	-0.2	-0.2	-0.4	-0.1	-0.2	-0.3	-0.6	-0.1	-0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.3	2.5	0.2	0.8	0.5	0.3	0.2	0.2	1.6	0.6	-0.1	-0.1	0.0	0.1	-0.3	0.4	0.8	0.1	0.6	0.3
Cholesterol lowering medication	0.1	0.1	0.8	-0.3	-0.3	-0.3	-0.1	-0.0	-0.0	-0.9	-0.0	-0.2	-0.3	-0.2	0.1	-0.7	0.1	0.1	-0.3	-0.1	-0.1
Pain experienced in last month	0.1	0.1	0.5	-0.4	0.4	0.1	-0.0	-0.3	-0.5	0.7	-0.1	-0.2	-0.1	-0.0	-0.5	0.6	-0.4	0.2	0.1	0.3	-0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.8	0.2	0.9	0.6	0.2	0.2	0.3	-0.5	0.1	0.1	0.0	0.1	0.4	0.1	0.2	0.0	0.3	-0.2	-0.1
Blood Red Count	0.0	0.5	1.9	-0.3	0.2	-0.4	-0.6	-0.7	-0.4	-0.5	-0.1	-1.0	-1.0	-1.0	-0.6	-1.4	-0.3	0.3	-1.1	-0.2	-0.5
Hair Pigment	0.0	0.2	1.3	-0.0	-1.1	-0.0	-0.1	0.1	-0.1	-1.0	-0.4	-0.3	-0.3	-0.4	-0.1	-0.3	-0.2	-0.8	0.1	-0.4	-0.5
Tanning	0.0	0.3	0.9	-0.8	-0.6	-0.3	-0.3	-0.5	-0.6	0.5	-0.5	-0.8	-0.9	-0.7	-0.6	-0.8	-0.5	-0.2	-0.2	-0.5	-0.6
Medication: Levothyroxine sodium	0.0	0.1	0.4	0.4	0.6	0.1	0.2	0.3	0.3	-0.2	0.1	-0.1	-0.2	-0.2	0.4	-0.6	0.3	0.2	-0.1	-0.1	0.1
Hearing difficulty/problems with background noise	0.0	0.0	0.2	-0.2	-0.2	-0.1	-0.1	-0.1	-0.2	0.5	0.1	-0.1	-0.0	-0.1	-0.2	-0.2	-0.1	0.0	-0.1	0.2	0.0
Number of self-reported non-cancer illnesses	0.0	0.1	0.4	-0.2	0.7	-0.3	-0.2	-0.2	-0.3	-0.5	-0.0	-0.0	0.2	-0.0	-0.2	0.2	-0.2	-0.1	-0.2	-0.1	0.0

Hub : Genes

INTS12

Models

Trait associations