[Hub]/) : Traits : Guilty feelings : ← →

chr11:112,135,760-113,969,669

Best TWAS P=3.03e-09 · Best GWAS P=2.43e-09 conditioned to 0.111

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Hypothalamus RP11-159N11.4 0.44 0.06 lasso 19 0.03 7.5e-02 3.8 5.2 2.5e-07 -0.20 0.10 0.29 FALSE
2 GTEx Heart Left Ventricle TTC12 0.39 0.24 enet 36 0.38 2.5e-21 5.4 5.6 1.9e-08 -0.16 0.06 0.94 FALSE
3 GTEx Uterus NCAM1 0.41 -0.01 lasso 11 -0.01 5.9e-01 3.8 5.6 2.1e-08 -0.21 0.08 0.07 FALSE
4 METSIM Adipose ANKK1 0.16 0.11 enet 13 0.16 9.8e-23 -4.3 -5.9 3.0e-09 0.24 0.90 0.09 TRUE
5 YFS Blood ANKK1 0.04 0.03 lasso 3 0.03 2.9e-09 -4.7 -5.2 1.6e-07 0.19 0.76 0.24 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ANKK1 0.04 0.02 blup 66 0.03 5.0e-04 4.3 5.7 1.2e-08 -0.22 0.03 0.90 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ANKK1 0.04 0.03 blup 67 0.04 6.3e-05 4.3 -5.3 1.4e-07 0.28 0.08 0.88 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma DRD2 0.06 0.07 lasso 2 0.07 6.6e-09 -5.1 5.2 2.6e-07 -0.75 0.09 0.91 TRUE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TTC12 0.25 0.12 blup 48 0.12 2.4e-08 5.1 5.4 7.7e-08 -0.28 0.03 0.97 TRUE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TTC12 0.36 0.30 lasso 3 0.29 6.0e-12 5.5 5.5 4.9e-08 -0.21 0.01 0.99 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma TTC12 0.21 0.20 lasso 4 0.22 1.2e-22 5.5 5.4 6.2e-08 -0.23 0.01 0.99 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors TTC12 0.07 0.06 blup 48 0.04 1.6e-02 5.1 5.8 6.0e-09 -0.26 0.01 0.75 FALSE