[Hub]/) : Traits : Frequency of tenseness / restlessness in last 2 weeks : ← →

chr3:48,381,826-50,546,340

Best TWAS P=1.02e-07 · Best GWAS P=7.01e-07 conditioned to 0.0284

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NICN1 0.20 0.12 lasso 17 0.13 6.7e-11 4.8 -5.2 2.2e-07 -0.91 0.05 0.95 FALSE
2 GTEx Adipose Subcutaneous NICN1-AS1 0.16 0.14 enet 20 0.14 2.4e-11 4.8 -5.2 1.5e-07 -0.93 0.05 0.94 FALSE
3 GTEx Cells EBV-transformed lymphocytes USP4 0.08 0.05 lasso 2 0.09 8.7e-04 5.0 5.3 1.4e-07 0.90 0.06 0.76 FALSE
4 GTEx Lung NICN1 0.12 0.12 enet 13 0.15 2.6e-11 5.0 -5.2 2.0e-07 -0.96 0.04 0.96 FALSE
5 GTEx Lung GPX1 0.04 0.02 enet 13 0.04 5.7e-04 -3.6 5.3 1.0e-07 0.60 0.12 0.44 TRUE
6 GTEx Nerve Tibial NICN1 0.13 0.15 enet 21 0.16 1.4e-11 4.7 -5.2 2.4e-07 -0.90 0.05 0.94 FALSE
7 GTEx Pituitary QRICH1 0.28 0.05 lasso 11 0.10 1.5e-03 4.8 5.2 1.7e-07 0.85 0.10 0.74 FALSE
8 GTEx Skin Sun Exposed Lower leg UBA7 0.04 0.01 lasso 8 0.00 2.9e-01 4.0 -5.1 2.7e-07 -0.44 0.10 0.37 FALSE
9 GTEx Skin Sun Exposed Lower leg KLHDC8B 0.06 0.08 enet 21 0.06 5.6e-06 4.8 5.2 2.4e-07 0.92 0.04 0.95 FALSE
10 GTEx Spleen AMT 0.44 0.37 lasso 15 0.39 5.6e-11 4.7 -5.2 1.7e-07 -0.96 0.04 0.95 FALSE
11 GTEx Thyroid GPX1 0.10 0.12 enet 23 0.11 9.1e-09 4.8 5.2 2.0e-07 0.92 0.05 0.94 FALSE
12 ROSMAP Brain Pre-frontal Cortex GPX1 0.23 0.25 lasso 10 0.30 1.5e-39 4.8 5.2 1.7e-07 0.89 0.04 0.95 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AMT 0.03 0.02 lasso 4 0.01 1.1e-02 4.9 -5.2 2.2e-07 -0.93 0.00 0.60 FALSE