[Hub]/) : Traits : Body mass index (BMI) :

chr3:134,986,214-137,368,142

Best TWAS P=1.26e-15 · Best GWAS P=9.84e-14 conditioned to 0.00965

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP2R3A 0.05 0.02 lasso 4 0.05 7.7e-07 7.0 5.6 2.2e-08 -0.32 0.18 0.74 FALSE
2 GTEx Artery Coronary SLC35G2 0.16 0.03 lasso 8 0.05 6.4e-03 6.4 -7.3 2.0e-13 0.51 0.15 0.40 FALSE
3 GTEx Brain Cerebellar Hemisphere RP11-731C17.2 0.16 0.02 enet 24 0.09 3.0e-03 -6.2 6.6 4.7e-11 -0.85 0.08 0.66 FALSE
4 GTEx Brain Cerebellum RP11-85F14.5 0.13 0.10 lasso 7 0.07 4.1e-03 -4.7 5.3 1.3e-07 -0.55 0.49 0.14 FALSE
5 GTEx Brain Cerebellum RP11-731C17.2 0.31 0.05 enet 39 0.12 2.3e-04 -4.7 5.2 2.6e-07 -0.42 0.34 0.13 FALSE
6 GTEx Breast Mammary Tissue (Male) RP11-85F14.5 0.08 0.12 lasso 1 0.06 1.6e-02 6.2 6.2 4.7e-10 -0.22 0.08 0.11 FALSE
7 GTEx Cells Transformed fibroblasts RP11-85F14.5 0.10 0.08 enet 38 0.09 3.9e-07 -4.7 6.6 4.6e-11 -0.54 0.95 0.03 FALSE
8 GTEx Esophagus Mucosa RP11-85F14.5 0.13 0.10 lasso 3 0.11 5.1e-08 -5.9 5.9 3.2e-09 -0.64 0.98 0.02 FALSE
9 GTEx Esophagus Muscularis RP11-731C17.2 0.16 0.03 enet 13 0.06 1.1e-04 3.6 5.4 8.2e-08 -0.11 0.44 0.33 FALSE
10 GTEx Lung RP11-85F14.5 0.07 0.05 lasso 19 0.05 8.8e-05 -5.9 6.2 5.5e-10 -0.67 0.92 0.03 FALSE
11 GTEx Muscle Skeletal RP11-85F14.5 0.10 0.08 lasso 17 0.09 6.3e-09 -4.7 5.9 3.1e-09 -0.39 0.95 0.05 FALSE
12 GTEx Muscle Skeletal RP11-731C17.2 0.15 0.12 lasso 16 0.12 3.8e-12 -4.7 6.1 8.5e-10 -0.50 1.00 0.00 FALSE
13 GTEx Skin Sun Exposed Lower leg RP11-85F14.5 0.04 0.01 enet 9 0.03 2.8e-03 -4.6 5.9 3.6e-09 -0.51 0.31 0.33 FALSE
14 GTEx Testis SLC35G2 0.17 0.19 lasso 10 0.18 1.5e-08 -4.6 -5.4 5.4e-08 0.58 0.94 0.06 FALSE
15 GTEx Testis RP11-85F14.5 0.12 0.03 enet 28 0.02 3.8e-02 -4.6 6.3 3.3e-10 -0.55 0.49 0.17 FALSE
16 GTEx Thyroid PPP2R3A 0.10 0.05 enet 18 0.06 1.3e-05 4.8 5.6 1.9e-08 -0.35 0.36 0.61 FALSE
17 GTEx Thyroid RP11-85F14.5 0.07 0.00 lasso 7 0.01 4.7e-02 -5.9 8.0 1.3e-15 -0.70 0.07 0.51 TRUE
18 YFS Blood MSL2 0.02 0.04 lasso 2 0.03 9.9e-11 6.4 -6.4 1.3e-10 0.30 0.19 0.81 FALSE
19 YFS Blood NCK1 0.01 0.02 enet 4 0.02 2.2e-06 -5.9 5.9 3.4e-09 -0.64 0.95 0.04 FALSE