[Hub]/) : Traits : Body mass index (BMI) : ← →

chr3:134,986,214-137,368,142

Best TWAS P=1.26e-15 · Best GWAS P=9.84e-14 conditioned to 0.00965

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	GTEx	Thyroid	RP11-85F14.5	0.07	0.00	lasso	7	0.01	4.7e-02	-5.9	8.0	1.3e-15	-0.70	0.07	0.51	TRUE
2	GTEx	Artery Coronary	SLC35G2	0.16	0.03	lasso	8	0.05	6.4e-03	6.4	-7.3	2.0e-13	0.51	0.15	0.40	FALSE
7	GTEx	Cells Transformed fibroblasts	RP11-85F14.5	0.10	0.08	enet	38	0.09	3.9e-07	-4.7	6.6	4.6e-11	-0.54	0.95	0.03	FALSE
3	GTEx	Brain Cerebellar Hemisphere	RP11-731C17.2	0.16	0.02	enet	24	0.09	3.0e-03	-6.2	6.6	4.7e-11	-0.85	0.08	0.66	FALSE
18	YFS	Blood	MSL2	0.02	0.04	lasso	2	0.03	9.9e-11	6.4	-6.4	1.3e-10	0.30	0.19	0.81	FALSE
15	GTEx	Testis	RP11-85F14.5	0.12	0.03	enet	28	0.02	3.8e-02	-4.6	6.3	3.3e-10	-0.55	0.49	0.17	FALSE
6	GTEx	Breast Mammary Tissue (Male)	RP11-85F14.5	0.08	0.12	lasso	1	0.06	1.6e-02	6.2	6.2	4.7e-10	-0.22	0.08	0.11	FALSE
10	GTEx	Lung	RP11-85F14.5	0.07	0.05	lasso	19	0.05	8.8e-05	-5.9	6.2	5.5e-10	-0.67	0.92	0.03	FALSE
12	GTEx	Muscle Skeletal	RP11-731C17.2	0.15	0.12	lasso	16	0.12	3.8e-12	-4.7	6.1	8.5e-10	-0.50	1.00	0.00	FALSE
11	GTEx	Muscle Skeletal	RP11-85F14.5	0.10	0.08	lasso	17	0.09	6.3e-09	-4.7	5.9	3.1e-09	-0.39	0.95	0.05	FALSE
8	GTEx	Esophagus Mucosa	RP11-85F14.5	0.13	0.10	lasso	3	0.11	5.1e-08	-5.9	5.9	3.2e-09	-0.64	0.98	0.02	FALSE
19	YFS	Blood	NCK1	0.01	0.02	enet	4	0.02	2.2e-06	-5.9	5.9	3.4e-09	-0.64	0.95	0.04	FALSE
13	GTEx	Skin Sun Exposed Lower leg	RP11-85F14.5	0.04	0.01	enet	9	0.03	2.8e-03	-4.6	5.9	3.6e-09	-0.51	0.31	0.33	FALSE
16	GTEx	Thyroid	PPP2R3A	0.10	0.05	enet	18	0.06	1.3e-05	4.8	5.6	1.9e-08	-0.35	0.36	0.61	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPP2R3A	0.05	0.02	lasso	4	0.05	7.7e-07	7.0	5.6	2.2e-08	-0.32	0.18	0.74	FALSE
14	GTEx	Testis	SLC35G2	0.17	0.19	lasso	10	0.18	1.5e-08	-4.6	-5.4	5.4e-08	0.58	0.94	0.06	FALSE
9	GTEx	Esophagus Muscularis	RP11-731C17.2	0.16	0.03	enet	13	0.06	1.1e-04	3.6	5.4	8.2e-08	-0.11	0.44	0.33	FALSE
4	GTEx	Brain Cerebellum	RP11-85F14.5	0.13	0.10	lasso	7	0.07	4.1e-03	-4.7	5.3	1.3e-07	-0.55	0.49	0.14	FALSE
5	GTEx	Brain Cerebellum	RP11-731C17.2	0.31	0.05	enet	39	0.12	2.3e-04	-4.7	5.2	2.6e-07	-0.42	0.34	0.13	FALSE