[Hub]/) : Traits : Weight : ← →

chr11:29,646,947-31,288,160

Best TWAS P=6.98e-13 · Best GWAS P=7.79e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ARL14EP 0.33 0.25 lasso 10 0.26 3.7e-08 6.7 -7.1 1.7e-12 -0.69 0.65 0.34 FALSE
2 GTEx Esophagus Gastroesophageal Junction ARL14EP 0.15 0.14 lasso 3 0.11 1.2e-04 6.7 -6.8 1.2e-11 -0.71 0.42 0.30 FALSE
3 GTEx Esophagus Muscularis ARL14EP 0.18 0.20 lasso 8 0.19 9.5e-12 6.9 -7.0 1.9e-12 -0.63 0.77 0.23 FALSE
4 GTEx Pancreas ARL14EP 0.16 0.08 lasso 6 0.07 1.0e-03 5.8 -6.5 8.4e-11 -0.62 0.28 0.16 FALSE
5 GTEx Pituitary ARL14EP 0.30 0.28 lasso 4 0.22 3.0e-06 7.0 -7.1 1.7e-12 -0.84 0.07 0.86 FALSE
6 ROSMAP Brain Pre-frontal Cortex MPPED2 0.25 0.29 lasso 7 0.29 4.4e-37 7.1 -7.2 7.0e-13 -0.97 0.01 0.99 TRUE
7 ROSMAP Brain Pre-frontal Cortex ARL14EP 0.08 0.07 enet 13 0.08 5.3e-10 6.9 -5.5 3.1e-08 -0.60 0.81 0.19 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma C11orf46 0.12 0.08 blup 34 0.07 5.7e-05 6.1 5.5 4.2e-08 0.67 0.05 0.57 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma MPPED2 0.07 0.01 blup 149 0.03 7.0e-05 7.0 -5.7 1.0e-08 -0.75 0.02 0.96 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C11orf46 0.05 0.02 lasso 2 0.02 9.9e-04 6.8 5.5 2.8e-08 0.62 0.04 0.31 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C11orf46 0.07 0.04 blup 34 0.07 2.5e-05 6.7 5.2 2.5e-07 0.71 0.04 0.89 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma C11orf46 0.11 0.05 enet 7 0.09 3.4e-07 -2.0 5.2 2.7e-07 0.64 0.61 0.38 FALSE