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chr11:29,646,947-31,288,160

Best TWAS P=6.98e-13 · Best GWAS P=7.79e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	ROSMAP	Brain Pre-frontal Cortex	MPPED2	0.25	0.29	lasso	7	0.29	4.4e-37	7.1	-7.2	7.0e-13	-0.97	0.01	0.99	TRUE
1	GTEx	Brain Cerebellum	ARL14EP	0.33	0.25	lasso	10	0.26	3.7e-08	6.7	-7.1	1.7e-12	-0.69	0.65	0.34	FALSE
5	GTEx	Pituitary	ARL14EP	0.30	0.28	lasso	4	0.22	3.0e-06	7.0	-7.1	1.7e-12	-0.84	0.07	0.86	FALSE
3	GTEx	Esophagus Muscularis	ARL14EP	0.18	0.20	lasso	8	0.19	9.5e-12	6.9	-7.0	1.9e-12	-0.63	0.77	0.23	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	ARL14EP	0.15	0.14	lasso	3	0.11	1.2e-04	6.7	-6.8	1.2e-11	-0.71	0.42	0.30	FALSE
4	GTEx	Pancreas	ARL14EP	0.16	0.08	lasso	6	0.07	1.0e-03	5.8	-6.5	8.4e-11	-0.62	0.28	0.16	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	MPPED2	0.07	0.01	blup	149	0.03	7.0e-05	7.0	-5.7	1.0e-08	-0.75	0.02	0.96	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C11orf46	0.05	0.02	lasso	2	0.02	9.9e-04	6.8	5.5	2.8e-08	0.62	0.04	0.31	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	ARL14EP	0.08	0.07	enet	13	0.08	5.3e-10	6.9	-5.5	3.1e-08	-0.60	0.81	0.19	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	C11orf46	0.12	0.08	blup	34	0.07	5.7e-05	6.1	5.5	4.2e-08	0.67	0.05	0.57	FALSE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C11orf46	0.07	0.04	blup	34	0.07	2.5e-05	6.7	5.2	2.5e-07	0.71	0.04	0.89	FALSE
12	The Cancer Genome Atlas	Stomach Adenocarcinoma	C11orf46	0.11	0.05	enet	7	0.09	3.4e-07	-2.0	5.2	2.7e-07	0.64	0.61	0.38	FALSE