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chr11:118,241,995-120,797,604

Best TWAS P=5.8e-11 · Best GWAS P=1.16e-09 conditioned to 0.0074

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Adipose Visceral Omentum	NLRX1	0.14	0.03	lasso	5	0.03	9.6e-03	5.4	-6.5	5.8e-11	0.05	0.01	0.95	TRUE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	HMBS	0.08	0.03	blup	38	0.04	1.7e-04	4.8	6.2	5.9e-10	-0.04	0.00	0.85	TRUE
3	GTEx	Breast Mammary Tissue	OAF	0.19	0.00	enet	23	0.02	4.2e-02	-5.7	-5.4	5.7e-08	0.65	0.03	0.83	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	HMBS	0.30	0.18	blup	38	0.18	1.0e-18	4.4	5.8	7.8e-09	-0.02	0.01	0.98	FALSE
8	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NLRX1	0.05	0.03	enet	5	0.05	2.4e-06	4.3	-5.5	4.6e-08	-0.01	0.02	0.72	FALSE
1	CommonMind	Brain Pre-frontal Cortex	NLRX1	0.04	0.03	enet	14	0.02	1.2e-03	-4.3	-5.3	9.5e-08	0.02	0.20	0.29	FALSE
5	GTEx	Vagina	HMBS	0.23	0.14	lasso	4	0.12	1.1e-03	4.7	5.3	1.1e-07	-0.01	0.10	0.30	FALSE
11	The Cancer Genome Atlas	Rectum Adenocarcinoma	HMBS	0.24	0.08	blup	38	0.04	3.6e-02	4.8	5.2	1.5e-07	0.02	0.00	0.22	FALSE
4	GTEx	Muscle Skeletal	RP11-110I1.14	0.24	0.12	lasso	9	0.15	2.4e-14	4.6	-5.2	2.5e-07	0.02	0.25	0.73	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	HMBS	0.13	0.04	lasso	2	0.04	9.0e-06	4.8	5.2	2.7e-07	-0.02	0.00	0.96	FALSE
6	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	HINFP	0.05	0.01	blup	46	0.02	1.3e-02	3.7	5.1	2.9e-07	0.03	0.02	0.27	FALSE