TWAS hub - OAF

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2260	0.0460	1.8e-09	0.089	0.094	0.145	0.140	0.139	5.3e-11	1.6e-11	3.1e-17	1.2e-16	1.4e-16
2	GTEx	Breast Mammary Tissue	0.1910	0.0670	3.8e-03	0.003	NA	0.017	NA	0.013	2.2e-01	NA	4.2e-02	NA	7.0e-02
3	GTEx	Breast Mammary Tissue (Male)	0.0183	0.1041	4.5e-01	0.002	NA	0.001	NA	0.002	2.8e-01	NA	3.1e-01	NA	2.9e-01
4	GTEx	Breast Mammary Tissue (Female)	0.1599	0.0958	7.9e-02	0.004	NA	-0.009	NA	-0.008	2.3e-01	NA	7.4e-01	NA	6.9e-01
5	GTEx	Cells Transformed fibroblasts	0.1940	0.0500	3.0e-05	0.145	NA	0.102	NA	0.126	5.1e-11	NA	4.6e-08	NA	1.1e-09
6	GTEx	Colon Transverse	0.1780	0.0620	4.5e-03	0.171	NA	0.141	NA	0.164	1.5e-08	NA	3.2e-07	NA	3.1e-08
7	GTEx	Esophagus Mucosa	0.2830	0.0740	2.6e-05	0.007	NA	0.021	NA	0.032	9.7e-02	NA	1.3e-02	NA	3.0e-03
8	GTEx	Esophagus Muscularis	0.2570	0.0550	2.1e-06	0.140	NA	0.117	NA	0.124	7.3e-09	NA	1.5e-07	NA	5.9e-08
9	GTEx	Heart Atrial Appendage	0.3250	0.0800	1.3e-04	0.164	NA	0.065	NA	0.166	7.6e-08	NA	6.9e-04	NA	6.4e-08
10	GTEx	Nerve Tibial	0.3829	0.0864	3.0e-05	0.043	NA	0.074	NA	0.094	5.3e-04	NA	6.1e-06	NA	3.3e-07
11	GTEx	Skin Sun Exposed Lower leg	0.1600	0.0510	9.7e-04	0.115	NA	0.118	NA	0.123	1.0e-09	NA	5.6e-10	NA	2.2e-10
12	METSIM	Adipose	0.0689	0.0253	9.0e-04	0.033	0.025	0.049	0.045	0.056	9.8e-06	1.1e-04	7.8e-08	2.0e-07	9.4e-09
13	YFS	Blood	0.0986	0.0209	9.0e-15	0.079	0.053	0.082	0.078	0.079	1.9e-24	6.4e-17	1.3e-25	3.4e-24	1.1e-24
14	TCGA	Breast Invasive Carcinoma	0.0288	0.0149	7.1e-03	0.001	0.012	0.002	NA	0.001	2.1e-01	1.1e-03	1.3e-01	NA	1.5e-01
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0829	0.0308	2.2e-05	0.063	0.040	0.037	NA	0.052	1.4e-07	2.3e-05	4.2e-05	NA	1.5e-06
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0870	0.0380	4.0e-03	0.089	0.056	0.081	NA	0.076	8.8e-06	3.7e-04	2.1e-05	NA	3.9e-05
17	TCGA	Prostate Adenocarcinoma	0.0740	0.0321	4.6e-04	0.055	0.037	0.048	NA	0.048	2.1e-06	9.3e-05	9.4e-06	NA	8.0e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Alcohol drinker status: Never	5.7	6.8	13.2	2.8	0.0	0.8	1.1	3.2	3.5	0.9	3.6	3.5	2.0	3.3	2.9	0.0	1.2	3.5	3.0	3.6
Diastolic blood pressure, automated reading	4.6	14.2	25.6	4.4	1.3	0.1	1.8	5.0	4.6	2.8	5.1	4.6	3.5	4.7	3.9	0.1	1.6	4.4	4.9	4.6
Medication: Bendroflumethiazide	4.4	6.7	13.4	3.7	-1.1	1.1	-0.2	2.5	3.2	0.5	2.8	3.2	2.5	3.3	2.0	-0.4	3.3	3.4	3.0	3.1
Illnesses of father: High blood pressure	4.2	5.2	11.4	2.9	1.0	-0.3	0.9	2.1	2.6	2.5	2.5	2.5	3.4	2.4	1.4	2.2	2.0	2.7	2.5	2.7
Systolic blood pressure, automated reading	4.0	11.5	24.7	4.2	0.6	0.6	-0.1	4.6	4.0	1.1	5.0	4.1	3.5	4.1	3.8	0.1	2.1	3.9	4.4	4.0
Illnesses of mother	3.9	4.8	9.5	-1.7	0.9	1.7	2.2	-1.6	-2.9	0.4	-2.5	-2.8	0.3	-2.9	-2.5	2.9	-1.0	-3.1	-1.8	-2.8
Medication: Ramipril	3.6	4.6	9.3	2.7	0.6	-1.0	-0.8	2.2	2.7	1.1	3.0	2.8	1.0	2.4	1.7	0.8	2.7	2.8	2.6	2.7
Medication: Ibuprofen (e.g. Nurofen)	3.5	4.5	8.5	-1.6	-1.7	-0.5	-0.3	-1.9	-2.9	-1.7	-2.4	-2.9	-1.9	-2.8	-2.7	1.0	-0.5	-2.9	-2.3	-2.9
Cardiovascular Disease	3.2	10.7	18.5	4.3	0.2	2.1	-1.9	3.7	4.0	-0.2	4.3	4.1	1.0	3.7	3.4	-2.2	3.2	4.1	4.1	3.9
High cholesterol (Self-reported)	3.2	5.7	10.8	3.0	-0.1	0.4	-0.8	3.1	2.9	1.0	3.3	2.9	1.5	3.2	2.6	-0.3	2.0	2.9	3.0	2.9
Systolic Blood Pressure	3.1	15.6	31.6	5.6	3.0	0.4	0.6	5.1	4.7	2.1	5.3	4.8	2.2	4.4	4.0	0.3	3.3	4.5	5.0	4.8
Breastfed as a baby	3.0	3.8	8.0	-1.7	1.8	0.4	2.8	-2.0	-2.2	0.5	-2.5	-2.1	-0.8	-2.0	-1.9	0.6	-2.2	-2.5	-2.2	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	3.0	4.6	13.8	2.3	-0.0	-1.7	1.4	2.2	2.0	3.7	2.5	1.9	1.0	2.4	1.3	2.3	2.9	2.0	2.2	2.1
Ever depressed for a whole week	3.0	3.7	6.2	2.3	0.8	-1.0	1.3	2.5	2.4	0.8	2.2	2.2	2.4	2.4	1.3	0.5	1.6	2.2	2.5	2.3
Supplements: Fish oil (including cod liver oil)	2.9	3.7	7.5	-1.2	0.1	0.3	1.3	-2.6	-2.6	0.5	-1.9	-2.7	-0.4	-2.5	-2.6	1.5	-0.8	-2.7	-2.2	-2.6
Medication: Blood pressure	2.8	4.9	15.0	3.9	1.8	0.9	-0.8	2.4	2.6	1.0	2.7	2.8	1.5	2.3	1.5	-0.4	2.0	2.6	2.8	2.6
Vascular/heart problems diagnosed by doctor	2.8	7.7	14.0	-3.7	-0.6	-1.7	1.3	-3.1	-3.3	0.2	-3.5	-3.5	-1.0	-3.1	-3.0	1.9	-2.9	-3.4	-3.6	-3.3
Heart attack/myocardial infarction (self-reported)	2.8	3.6	6.2	2.0	2.0	0.6	-0.2	2.2	2.3	1.2	2.4	2.5	1.2	2.5	2.2	0.3	1.0	2.3	2.2	2.4
Alzheimer’s Disease (in mother)	2.7	3.1	6.7	-1.6	-1.0	1.0	-0.7	-2.3	-2.3	-0.5	-1.5	-2.3	-0.6	-2.6	-2.3	-1.2	-0.8	-2.0	-2.4	-2.4
Fed-up feelings	2.6	4.8	15.0	2.6	-0.6	-1.5	-0.0	2.8	2.2	1.1	3.1	2.2	0.8	2.5	1.9	-0.3	3.9	2.4	2.9	2.1
Multivitamins +/- minerals	2.6	3.3	8.7	-1.6	-0.6	0.7	-0.2	-2.1	-2.2	0.3	-2.1	-2.1	-1.7	-2.2	-3.0	2.0	-0.1	-2.2	-1.7	-2.2
Chronic bronchitis/emphysema (mother)	2.6	3.0	8.6	1.7	0.0	-2.0	-1.1	1.8	2.2	-0.3	1.7	2.1	0.8	2.0	2.9	-0.7	1.4	2.2	1.4	2.2
Worry too long after embarrassment	2.6	4.3	18.6	1.8	-1.5	-0.0	-0.6	2.3	2.1	1.4	2.8	2.0	0.3	2.7	2.0	0.9	4.3	2.3	2.3	2.0
Alcohol intake frequency.	2.6	5.9	12.8	2.3	-0.8	-0.5	-0.4	3.3	3.0	-0.1	3.6	2.9	0.4	3.0	3.0	-1.2	2.6	3.1	2.9	3.0
Diabetes (mother)	2.5	3.2	6.5	-2.0	-1.5	-1.8	-2.2	-1.9	-2.0	-1.2	-1.4	-1.9	-2.5	-1.4	-1.5	-1.0	-0.8	-1.9	-2.2	-2.0
Serious illness, injury or assault to yourself	2.5	3.1	6.8	1.3	1.6	0.1	2.2	2.1	2.0	1.1	1.9	2.0	2.6	1.8	2.0	0.8	0.6	1.9	1.8	2.0
Ever unenthusiastic/disinterested for a whole week	2.5	3.0	5.8	2.4	1.4	-0.6	1.3	1.7	2.0	2.2	1.5	1.9	1.4	2.2	0.7	0.6	2.3	1.9	2.1	2.0
Medication: Simvastatin	2.5	3.7	8.4	2.3	-0.6	0.1	-1.0	2.9	2.1	-0.0	2.8	2.1	0.4	2.5	1.8	-0.4	2.1	2.2	2.7	2.1
Neuroticism score	2.5	5.2	22.8	2.3	-0.8	-0.8	-0.0	2.2	2.3	2.3	2.8	2.2	-0.2	2.7	1.8	1.2	4.8	2.5	2.5	2.2
Illnesses of father: None of the above (group 1)	2.5	3.0	6.7	-2.6	0.3	-0.4	1.4	-1.7	-2.1	-0.4	-2.6	-2.0	-1.2	-1.9	-0.8	-0.9	-1.9	-2.2	-2.1	-2.1
Neuroticism (2016)	2.4	3.5	9.9	1.2	1.2	-1.9	1.5	2.2	1.4	2.5	2.0	1.3	1.2	1.3	1.5	3.2	2.9	1.4	2.0	1.4
Heart attack	2.4	3.0	5.2	1.8	1.9	0.7	-0.5	2.0	2.1	0.8	2.3	2.3	1.1	2.3	2.1	0.0	0.8	2.1	2.0	2.1
Medication: Seretide 50 evohaler	2.4	2.8	5.7	2.0	-0.4	-0.1	-0.1	2.1	1.8	0.1	2.4	1.9	1.4	1.6	2.3	-2.0	0.8	1.9	2.3	1.8
Supplements: Vitamin C	2.4	2.9	5.8	-1.8	-0.4	0.9	-0.1	-1.8	-2.3	-0.3	-1.9	-2.4	-1.5	-2.2	-1.9	0.3	-1.4	-2.3	-1.8	-2.3
Hypertension (Self-reported)	2.4	6.6	14.4	3.8	0.6	1.3	-1.0	3.0	3.1	0.2	3.2	3.3	0.9	2.9	2.4	-1.7	2.5	3.1	3.4	3.1
Type 2 Diabetes (T2D) (2012)	2.3	2.6	4.3	2.1	0.3	0.8	-1.1	1.6	2.0	1.7	1.6	2.1	0.1	1.7	1.5	1.5	1.9	1.9	2.0	1.9
Maternal smoking around birth	2.3	3.4	7.0	1.3	0.1	-1.1	2.1	1.9	2.1	1.4	2.0	2.1	2.6	2.0	1.5	1.1	2.4	2.2	1.7	2.1
Health satisfaction	2.3	3.0	7.3	2.7	1.3	1.0	-0.0	2.3	1.9	1.1	2.7	2.1	0.8	2.0	1.1	0.7	0.6	1.9	2.4	1.8
Pulse wave peak to peak time	2.2	2.6	6.7	-0.5	-1.0	-0.5	-1.1	-1.9	-2.1	-0.6	-2.1	-2.0	-1.6	-1.8	-2.6	0.3	0.1	-2.0	-1.7	-2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.5	4.4	1.7	-0.9	0.3	1.0	1.9	2.0	1.2	1.9	2.0	0.6	2.0	1.7	-0.3	1.5	2.0	2.1	1.9
Wears glasses or contact lenses	2.2	2.5	6.3	2.5	-0.2	-0.4	-0.9	2.0	1.9	1.3	2.1	2.0	0.3	2.3	0.9	0.4	0.4	1.7	2.2	1.8
Reaction Time	2.1	3.9	12.8	-3.6	1.9	1.5	0.7	-2.3	-2.0	-2.5	-2.3	-1.9	0.4	-2.3	-0.2	-0.5	-1.9	-1.9	-2.6	-1.9
Vitamin and mineral supplements	2.1	2.8	6.0	1.9	0.4	-0.8	-0.5	1.8	2.1	0.9	1.8	2.1	1.3	2.1	2.5	-0.5	1.5	2.2	1.4	2.2
High blood pressure	2.1	5.9	12.4	3.5	0.7	1.5	-1.0	2.8	2.9	-0.4	3.1	3.0	0.8	2.6	2.4	-1.7	2.4	2.9	3.2	2.8
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	10.5	2.5	0.4	-0.7	2.2	1.9	1.9	0.6	2.6	1.8	0.6	1.7	0.9	1.3	3.2	1.8	2.3	1.8
Guilty feelings	2.1	3.1	11.1	1.1	-0.8	-0.1	0.5	2.0	1.7	2.5	2.2	1.5	-0.3	2.1	1.7	1.4	3.3	1.8	2.0	1.6
Coronary Artery Disease (CAD)	2.0	2.4	6.2	2.5	0.9	1.0	-0.7	2.0	1.7	0.5	1.9	1.9	0.2	1.6	1.0	-0.3	2.2	1.7	2.0	1.7
Neuroticism	2.0	4.9	17.1	2.1	-0.2	-0.2	-0.4	2.5	2.4	1.5	2.9	2.4	0.4	2.8	2.1	1.1	4.1	2.6	2.6	2.4
Medication: Lansoprazole	2.0	2.3	4.8	1.3	-0.2	-1.1	0.1	1.8	1.8	-0.1	2.2	1.8	1.5	2.0	1.9	-0.9	0.1	1.9	2.0	1.8
Qualifications: O levels/GCSEs or equivalent	2.0	3.2	5.8	-0.9	0.3	-1.2	0.8	-2.2	-2.0	-2.4	-2.3	-2.2	-0.7	-1.9	-2.3	0.0	-2.1	-2.1	-2.2	-2.0
Schizophrenia vs Biploar Disorder	1.9	2.5	6.2	2.5	0.1	-0.6	1.8	2.0	1.8	1.4	1.7	1.9	1.1	2.0	1.0	-1.5	-0.8	1.7	2.3	0.0
Chronotype (morning person)	1.9	4.3	13.7	-3.7	-2.6	-1.3	-1.8	-2.6	-2.0	-1.7	-1.9	-2.3	-1.6	-2.1	-1.0	-1.4	-1.4	-1.8	-2.6	-2.0
Average weekly spirits intake	1.9	2.3	6.5	-1.3	2.1	0.1	1.3	-1.9	-1.6	0.6	-1.7	-1.5	-0.3	-1.5	-1.8	-0.0	-2.5	-1.7	-1.6	-1.6
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	4.8	2.2	0.1	0.4	0.6	1.8	1.6	1.1	1.9	1.7	0.3	1.8	1.3	0.2	1.6	1.6	1.8	1.6
Qualifications: None of the above	1.9	4.0	8.5	2.1	0.1	0.7	-0.8	2.9	2.2	0.7	2.8	2.3	1.5	1.8	2.2	0.8	2.9	2.3	2.7	2.2
Mean time to correctly identify matches	1.9	3.6	9.8	-3.0	1.6	0.5	0.5	-2.0	-1.9	-3.1	-2.0	-1.9	0.3	-2.0	-0.5	-1.2	-2.4	-1.9	-2.4	-1.9
Cholesterol lowering medication	1.9	2.9	7.4	2.7	-1.2	0.7	-1.0	2.1	1.9	-0.6	2.3	1.9	0.4	2.1	1.4	-1.1	0.8	1.9	2.2	1.9
Age when periods started (menarche)	1.8	4.2	9.0	-2.6	0.7	0.7	-0.4	-2.3	-2.6	-0.5	-2.6	-2.7	-1.2	-3.0	-2.3	1.0	-0.7	-2.6	-2.5	-2.6
Medication: Atenolol	1.8	2.2	7.3	1.7	-1.2	1.4	-2.4	1.5	1.2	-0.7	2.0	1.3	-0.7	1.2	0.4	-0.2	2.7	1.4	1.8	1.1
Waist circumference	1.8	6.7	15.7	3.0	-4.0	1.0	-2.5	2.2	2.7	-1.5	3.2	2.9	0.8	3.2	1.6	-2.1	2.8	3.0	2.9	2.6
Medication: Ibuprofen	1.8	2.2	4.0	-0.9	-1.6	0.1	0.2	-1.4	-1.9	-1.1	-1.4	-1.8	-1.2	-1.9	-2.0	1.9	0.5	-1.9	-1.4	-1.9
Heart disease (mother)	1.8	2.2	3.9	1.5	1.0	-1.3	-1.5	1.4	1.7	0.7	1.3	1.8	0.5	2.0	1.9	-1.9	0.2	1.7	1.4	1.7
Ever smoked	1.8	3.1	4.8	2.1	0.0	0.1	1.7	1.7	2.2	1.4	1.6	2.2	2.0	2.0	1.3	1.4	1.6	2.2	2.0	2.1
Irritability	1.8	3.0	11.7	1.9	-1.4	-1.1	-0.6	1.9	1.8	0.3	2.1	1.7	1.1	2.2	1.3	-0.2	3.4	2.0	2.1	1.7
Smoking Status	1.7	4.1	6.9	2.6	0.2	-0.7	1.5	2.0	2.5	1.7	2.1	2.6	2.6	2.5	1.6	1.0	1.2	2.5	2.2	2.5
Angina	1.7	2.2	5.1	2.3	1.1	0.2	-0.6	1.4	1.6	0.6	1.9	1.8	1.5	1.8	1.2	0.6	1.8	1.7	1.6	1.7
Hand grip strength (right)	1.7	4.6	12.6	-3.6	1.6	-2.0	1.5	-2.9	-2.3	0.3	-3.1	-2.1	-0.0	-2.2	-0.7	0.1	-2.0	-2.4	-3.0	-2.2
Pulse wave Arterial Stiffness index	1.7	1.9	5.2	0.3	0.7	0.2	1.2	1.6	1.8	0.4	1.7	1.7	1.4	1.6	2.3	-0.4	-0.2	1.8	1.5	1.9
Length of working week for main job	1.7	1.9	11.5	0.1	-3.2	-0.0	-3.4	0.0	0.8	-1.4	0.4	0.8	-1.8	0.6	0.1	-1.1	0.9	0.9	0.6	0.7
Leg fat percentage (right)	1.7	6.3	12.9	2.6	-2.7	0.5	-3.6	1.8	2.8	-0.9	2.9	3.0	0.5	3.3	2.0	-1.2	3.2	3.0	2.6	2.7
Migraine (self-reported)	1.7	2.1	4.4	-1.2	-1.5	0.7	0.2	-1.7	-2.1	0.5	-1.0	-2.0	-1.3	-1.3	-1.3	-1.3	-1.3	-1.8	-1.6	-2.1
Mineral and other dietary supplements	1.7	2.3	4.3	1.3	-0.5	-1.9	-1.1	1.6	1.9	-0.3	1.3	2.0	1.2	2.0	2.0	-0.9	1.1	2.1	1.4	1.9
Tinnitus: Yes, now most or all of the time	1.7	2.0	4.0	2.0	0.0	0.8	1.1	1.7	1.6	2.0	1.5	1.6	1.7	1.0	0.4	1.4	0.8	1.5	1.7	1.5
Medication: Lisinopril	1.7	2.2	8.8	3.0	-1.0	1.4	-1.9	1.2	1.4	-0.8	1.8	1.4	0.6	1.1	0.3	-0.8	1.9	1.4	1.8	1.4
Leg fat percentage (left)	1.7	6.2	12.6	2.8	-2.9	0.4	-3.5	1.6	2.8	-1.2	2.8	3.0	0.8	3.2	1.7	-1.7	3.0	3.0	2.5	2.6
Body mass index (BMI)	1.6	6.7	20.8	2.9	-4.6	0.0	-3.8	1.6	2.3	-2.3	3.0	2.5	0.4	2.9	1.2	-2.4	3.0	2.7	2.3	2.2
Arm fat percentage (left)	1.6	6.2	19.6	2.6	-4.4	-0.3	-3.7	1.5	2.4	-1.3	2.9	2.5	0.8	2.9	1.2	-1.9	3.1	2.8	2.2	2.3
Waist Hip Ratio (WHR)	1.5	6.6	12.6	2.2	1.4	-0.1	1.0	3.5	3.2	1.7	2.9	3.3	1.4	3.3	3.4	-0.4	1.8	3.1	3.5	3.2
Arm fat percentage (right)	1.5	5.8	18.2	2.5	-4.3	-0.5	-3.6	1.4	2.3	-1.3	2.8	2.4	0.8	2.8	1.0	-1.3	3.2	2.6	2.2	2.2
Worrier / anxious feelings	1.5	2.8	7.1	1.8	-1.1	-1.0	-0.3	1.4	2.1	0.9	2.0	2.0	-0.0	2.3	1.7	0.1	2.7	2.2	1.8	2.0
Happiness	1.5	1.8	6.7	2.6	1.0	-0.5	-0.3	2.5	1.2	-0.7	1.8	1.2	0.6	1.1	0.6	-0.4	0.7	1.1	2.2	1.2
Standing height	1.5	14.5	27.9	-4.9	-2.3	1.2	2.1	-5.2	-4.5	-1.5	-5.3	-4.5	-0.9	-4.5	-3.3	0.2	-3.7	-4.5	-5.3	-4.5
Angina (self-reported)	1.5	2.0	4.0	2.0	1.4	0.2	-0.6	1.4	1.6	0.3	1.6	1.8	1.6	1.7	1.2	0.5	1.6	1.6	1.5	1.6
Qualifications: nursing, teaching	1.5	2.3	5.8	-1.3	-1.7	0.7	-1.2	-1.7	-1.6	-2.4	-1.7	-1.7	-1.5	-2.0	-1.1	0.8	0.2	-1.6	-1.7	-1.7
Medication: Blood pressure	1.5	2.9	5.0	2.0	-0.6	0.9	-1.0	1.7	2.1	-0.5	2.2	2.2	0.2	2.2	2.1	-1.2	1.5	2.2	1.9	2.1
Age started oral contraceptive pill	1.5	1.9	10.3	-0.0	-1.5	1.3	-3.2	-0.7	-0.4	-2.4	-0.5	-0.4	-1.1	-0.5	-0.6	-2.6	-1.6	-0.4	-0.4	-0.5
BMI	1.4	8.4	30.4	3.5	-5.5	0.5	-4.4	1.7	2.6	-1.6	3.2	2.7	0.6	3.1	1.1	-2.7	3.2	3.1	2.5	2.4
Average weekly fortified wine intake	1.4	1.7	4.3	2.1	1.9	-1.6	1.0	0.9	1.1	1.7	0.3	1.1	1.5	1.2	0.2	1.8	0.7	0.9	1.0	1.1
Taking other prescription medications	1.4	2.1	4.7	2.2	-0.4	-0.3	0.0	1.5	1.6	1.0	2.0	1.8	0.1	2.0	1.1	-0.4	1.8	1.8	1.9	1.6
Past tobacco smoking	1.4	2.6	6.3	-2.5	0.9	0.9	-0.2	-1.8	-2.1	-1.2	-1.4	-2.2	-1.2	-2.1	-1.2	-0.9	-0.9	-2.0	-2.0	-2.1
Lung cancer (father)	1.4	1.7	8.4	-0.1	-2.9	0.2	-2.6	-0.2	-0.8	-1.4	-0.9	-0.9	-1.6	-0.7	-0.6	-1.7	1.4	-0.6	-0.2	-0.9
Pulse wave reflection index	1.4	1.7	3.0	0.7	1.7	1.3	1.2	1.7	1.5	1.1	1.7	1.4	0.6	1.3	1.7	-0.3	0.0	1.4	1.5	1.6
Forced vital capacity (FVC), Best measure	1.4	5.2	12.5	-2.3	0.5	-0.2	2.5	-2.7	-2.7	0.0	-3.5	-2.6	-0.0	-2.9	-1.9	0.1	-2.5	-2.8	-3.0	-2.7
Mouth/teeth dental problems: Loose teeth	1.4	1.7	4.8	1.3	0.5	-0.1	0.5	1.6	1.5	0.7	1.3	1.6	1.1	1.3	2.2	0.2	1.7	1.5	1.4	1.4
Commuting to job workplace: Car/motor vehicle	1.4	1.6	7.0	0.1	1.1	-0.0	0.2	1.6	1.4	2.6	1.3	1.6	0.6	1.2	1.8	1.0	0.4	1.2	1.4	1.4
Mood swings	1.4	2.6	17.4	1.2	-1.3	-1.0	-0.7	1.3	1.1	2.0	2.0	0.9	-0.9	1.5	1.1	0.7	4.2	1.4	1.6	1.0
Alzheimer’s Disease (in father)	1.3	1.5	3.9	1.1	-0.9	-0.0	-0.9	1.8	1.2	0.9	2.0	1.4	-0.2	1.1	1.7	-0.5	1.2	1.3	1.3	1.2
Major Depression (MDD)	1.3	1.6	5.6	1.9	0.1	-0.8	1.2	0.8	1.3	2.4	0.7	1.4	1.2	1.6	0.7	1.7	0.9	1.2	1.1	0.0
Noisy workplace	1.3	1.6	2.9	1.6	-1.4	-0.5	-1.5	1.7	1.3	-1.2	1.7	1.3	0.3	1.1	1.0	-0.1	1.2	1.2	1.6	1.3
Arm fat mass (right)	1.3	5.4	23.7	2.3	-4.9	0.1	-3.5	1.1	2.0	-1.8	2.5	2.1	0.3	2.5	0.9	-1.9	2.9	2.4	1.9	1.8
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	6.7	-2.6	-1.2	-1.0	1.5	-1.3	-1.5	0.2	-1.6	-1.7	-1.2	-1.5	-0.6	0.4	-2.0	-1.6	-1.6	-1.5
Eye problems/disorders: None of the above	1.3	1.5	6.0	0.9	-0.5	-2.5	-0.5	1.2	1.2	0.0	1.3	1.2	1.7	1.5	0.7	-0.9	1.0	1.3	1.6	1.1
Medication: Omeprazole	1.3	1.5	7.0	0.2	-2.7	-0.2	-1.9	0.5	0.8	-0.6	0.6	1.1	-1.5	0.9	1.2	-2.1	1.3	1.1	0.7	0.8
Long-standing illness, disability or infirmity	1.3	2.0	4.7	2.2	0.9	-1.0	0.4	1.4	1.8	0.9	1.9	1.8	0.1	2.0	1.3	-0.7	0.7	1.8	1.5	1.8
Medication for cholesterol	1.3	1.9	3.8	-1.9	0.1	-0.1	0.2	-1.8	-1.7	0.5	-1.8	-1.6	0.5	-1.9	-1.9	0.1	-1.2	-1.6	-1.7	-1.7
Number of self-reported non-cancer illnesses	1.3	2.2	7.2	1.7	-1.4	-0.2	-1.2	1.5	1.3	0.4	2.0	1.4	-1.8	1.4	1.1	-1.3	2.7	1.5	1.6	1.2
Leg fat mass (left)	1.3	5.0	17.6	2.5	-4.2	0.8	-3.3	1.0	2.0	-1.6	2.2	2.2	0.6	2.6	1.0	-2.1	2.6	2.4	1.8	1.9
Prostate Cancer	1.2	1.6	4.6	-1.2	-1.3	-1.9	-1.1	-1.2	-1.1	-2.1	-1.6	-1.1	-0.4	-0.6	-0.9	-1.4	-0.8	-1.0	-1.5	-1.1
Height	1.2	23.2	43.7	-4.9	-4.0	1.7	1.4	-6.2	-6.0	-3.7	-5.8	-5.9	-0.8	-6.2	-4.7	0.2	-4.2	-5.9	-6.6	-5.9
Number of treatments/medications taken	1.2	2.2	4.7	2.0	-0.7	0.0	0.2	1.5	1.8	0.7	2.2	1.9	0.3	1.9	1.9	-0.6	1.4	1.9	1.5	1.8
High blood pressure (mother)	1.2	1.7	3.4	1.1	-0.8	-1.4	-1.8	0.6	1.7	-0.1	1.6	1.7	0.5	1.8	1.0	-1.0	0.3	1.8	1.0	1.7
Financial difficulties in last 2 years	1.2	1.7	3.8	1.9	-1.5	-1.9	0.1	1.3	1.1	1.2	1.7	1.1	1.0	1.0	0.4	-0.2	1.9	1.3	1.3	1.1
Emphysema/chronic bronchitis	1.2	1.3	2.4	1.5	1.1	1.5	1.2	1.4	1.3	-0.1	1.0	1.4	1.1	1.0	1.0	-0.6	0.0	1.3	1.2	1.4
Leg fat mass (right)	1.2	4.8	17.9	2.2	-4.2	0.7	-3.4	1.1	2.0	-1.4	2.2	2.1	0.4	2.5	1.2	-1.7	2.7	2.3	1.9	1.9
Had major operations	1.2	1.4	3.6	1.3	1.9	0.5	0.3	1.3	1.2	1.5	1.1	1.3	0.2	1.5	1.4	0.7	0.7	1.0	1.3	1.2
Smoking status: Previous	1.2	1.8	3.3	1.6	-1.6	-0.9	-1.1	1.5	1.7	0.3	1.1	1.8	0.9	1.7	1.4	0.2	0.3	1.7	1.6	1.7
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	7.5	-2.7	-1.8	0.9	0.6	-2.2	-1.7	0.6	-2.0	-1.6	-1.6	-1.7	-0.7	-0.3	-0.2	-1.5	-2.1	-1.7
Arm fat mass (left)	1.2	4.9	26.3	1.9	-5.1	0.2	-3.6	0.7	1.7	-1.8	2.2	1.8	0.4	2.2	0.6	-2.1	2.6	2.0	1.5	1.5
Fasting Glucose	1.1	1.3	3.6	0.3	0.7	-0.5	-0.7	1.1	1.3	-1.0	1.2	1.4	1.1	1.1	1.9	-1.6	-0.3	1.4	0.9	1.4
Sitting height	1.1	7.6	14.6	-3.4	-2.3	1.1	2.1	-3.8	-3.1	-0.7	-3.3	-3.1	-1.1	-3.2	-2.3	-0.4	-2.9	-3.2	-3.8	-3.1
Alcohol intake versus 10 years previously	1.1	1.7	6.1	-0.2	-0.6	1.0	-0.6	0.8	1.4	-0.3	1.4	1.4	0.9	1.4	2.5	-1.5	1.9	1.5	0.8	1.4
High blood pressure (siblings)	1.1	1.6	3.7	0.7	-0.5	0.5	-1.3	1.1	1.5	0.5	1.9	1.4	-0.3	1.5	1.7	-1.3	1.3	1.6	1.1	1.5
Body fat percentage	1.1	4.5	15.2	2.0	-3.9	0.1	-3.2	1.1	2.0	-1.1	2.3	2.2	0.7	2.6	1.2	-1.7	2.6	2.4	1.8	1.9
Overall health rating	1.1	2.4	9.5	3.1	-0.8	-0.8	-0.7	1.5	1.5	-0.5	2.4	1.4	1.3	2.0	0.3	-0.3	1.6	1.7	1.9	1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	9.7	1.0	-0.1	-1.2	0.8	0.5	0.5	0.8	0.5	0.4	-0.0	0.9	0.2	3.1	2.1	0.4	0.5	0.5
Eye problems/disorders: Cataract	1.1	1.2	4.2	-1.5	0.3	2.1	0.8	-0.9	-0.5	-1.7	-1.0	-0.5	-0.4	-1.1	-0.2	-1.0	-2.0	-0.5	-1.2	-0.5
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	5.9	0.5	-2.2	0.4	-1.7	0.5	0.8	-1.4	0.6	0.9	-0.9	0.7	0.6	-2.4	1.0	1.0	0.7	0.7
Schizophrenia (2018)	1.0	2.1	6.3	2.5	0.3	1.4	-0.6	2.1	1.6	2.2	1.2	1.7	-1.0	1.4	1.1	0.4	0.0	1.4	2.1	0.0
Bipolar Disorder (2011)	1.0	0.9	2.4	-1.5	-0.0	0.9	-0.5	-1.1	-1.5	-1.6	-1.1	-1.4	-0.2	-1.5	-0.9	-0.3	0.0	0.0	0.0	0.0
HDL Cholesterol	1.0	1.6	5.2	-1.6	2.3	0.7	1.7	-1.1	-0.8	2.2	-1.1	-0.8	0.0	-0.9	-0.6	2.1	0.1	-0.8	-1.0	-0.8
Hypothyroidism (self reported)	1.0	2.2	6.0	1.5	0.4	0.5	-0.5	1.5	1.8	1.0	2.5	2.0	0.6	1.8	1.7	0.5	1.3	1.9	1.8	1.8
Medication: Metformin	1.0	1.4	11.0	-0.3	-3.3	0.9	-1.9	-0.9	-0.6	-0.6	-0.2	-0.4	-1.3	-0.7	-1.1	0.5	1.5	-0.5	-0.3	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	5.0	0.8	0.2	-1.4	-0.2	1.3	2.1	0.1	1.7	1.9	0.2	2.2	1.9	-1.4	-0.1	2.0	1.4	2.2
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	4.4	0.3	-0.7	1.3	-1.3	0.8	1.1	-0.0	1.1	1.0	-0.4	0.6	1.5	1.0	2.1	1.3	0.8	1.1
Depression (self-reported)	1.0	1.2	11.7	0.3	-1.1	-3.4	-0.6	0.5	0.3	0.4	0.9	0.2	-0.1	0.9	0.5	0.7	1.7	0.5	0.7	0.4
Medication: Amlodipine	1.0	1.4	5.7	2.4	0.9	-0.1	-0.8	1.3	1.1	-0.2	1.7	1.2	0.1	1.3	0.5	-1.3	0.7	1.1	1.7	1.0
Shortness of breath walking on level ground	1.0	1.2	2.4	0.9	-1.5	-0.7	-0.8	1.1	1.2	-0.5	1.5	1.3	-0.4	1.5	0.9	-1.6	-0.0	1.2	1.1	1.2
Knee pain experienced in last month	1.0	1.5	3.0	1.3	-0.6	-0.4	0.3	1.5	1.2	1.4	1.6	1.3	0.2	1.1	1.4	1.2	1.7	1.4	1.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	4.5	-1.6	1.1	0.5	0.5	-1.6	-1.8	0.1	-2.1	-1.7	-0.2	-1.7	-0.6	-1.5	-1.5	-1.8	-2.0	-1.8
Miserableness	1.0	1.7	8.5	1.2	0.5	-0.5	1.1	1.3	0.9	2.0	1.6	0.8	-0.2	1.1	0.4	1.3	2.9	0.9	1.6	0.8
Lupus	0.9	1.3	5.5	-0.1	2.3	-2.2	2.0	0.4	0.8	1.8	-0.2	0.7	-0.2	1.0	0.9	-0.1	-0.4	0.6	0.3	1.0
Townsend deprivation index at recruitment	0.9	1.3	5.8	2.4	0.1	-0.3	1.3	1.3	1.1	-0.4	1.5	1.0	0.7	1.2	0.2	-1.4	0.3	1.1	1.2	1.1
Forced vital capacity (FVC)	0.9	3.6	9.2	-1.8	1.2	-0.2	2.8	-2.4	-1.9	0.8	-3.0	-1.9	0.3	-2.2	-1.3	0.3	-1.8	-2.1	-2.6	-2.0
Diabetes (self-reported)	0.9	1.4	4.1	-0.4	-1.4	-0.0	-2.0	-0.9	-1.3	-1.2	-1.3	-1.0	-1.4	-1.5	-1.4	-0.0	0.8	-1.3	-0.6	-1.3
Impedance of arm (right)	0.9	4.0	11.3	-3.4	1.4	-1.0	1.7	-2.0	-2.1	1.2	-2.8	-2.2	0.1	-2.4	-1.2	2.4	-1.5	-2.2	-2.4	-2.0
Hair/balding pattern: Pattern 3	0.9	1.4	2.4	1.0	1.1	0.9	0.2	1.4	1.5	0.6	1.0	1.4	0.4	1.5	1.0	0.0	1.5	1.5	1.6	1.5
Medication: Cholesterol lowering	0.9	1.3	6.4	1.5	1.1	0.3	-0.4	1.1	1.0	0.5	1.2	1.1	0.9	1.4	0.5	0.7	2.5	1.1	1.2	1.0
Loud music exposure frequency	0.9	1.0	3.6	1.5	-0.5	1.0	0.6	1.1	0.7	0.9	1.2	0.7	1.9	0.5	0.8	1.4	0.3	0.7	0.8	0.8
Comparative body size at age 10	0.9	2.4	4.6	1.6	-1.4	-1.2	-1.6	1.2	1.8	-0.5	1.6	1.8	0.4	2.1	1.5	-0.7	2.0	1.9	1.5	1.7
Whole body fat mass	0.9	3.8	20.9	1.6	-4.6	0.4	-2.9	0.6	1.5	-1.5	1.8	1.6	0.5	2.1	0.8	-1.9	2.3	1.8	1.3	1.4
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	12.6	0.8	-3.6	-0.9	-1.9	0.5	0.1	-0.1	0.2	0.0	-2.3	0.2	-0.6	-0.0	0.8	0.1	0.3	-0.0
Breast cancer (self-reported)	0.9	1.0	3.6	-1.2	0.4	0.3	0.7	-0.6	-1.1	-1.0	-0.9	-1.1	0.4	-1.2	-0.7	-1.6	-1.9	-1.1	-0.9	-1.1
Mother’s age at death	0.9	1.1	2.9	-1.3	-0.9	0.0	-0.0	-1.6	-1.1	-0.1	-1.5	-1.0	-1.7	-1.2	-1.0	-0.0	0.0	-1.1	-1.1	-1.1
Commuting to job workplace: Cycle	0.9	1.1	4.4	-2.1	-1.4	0.1	-0.1	-1.3	-1.2	0.1	-1.0	-1.3	-0.9	-1.4	-0.4	0.3	0.1	-1.1	-1.2	-1.2
Neuroticism (Nagel 2018)	0.8	1.9	9.2	1.5	-0.3	-0.5	0.1	1.8	1.1	1.1	1.9	1.0	-0.1	1.5	0.9	1.7	3.0	1.2	1.7	1.0
HbA1C	0.8	0.9	6.2	0.4	0.6	-2.5	1.1	-0.4	-0.8	-0.1	-0.9	-0.8	0.0	-0.4	-1.4	0.0	-0.7	-0.9	-0.4	-0.9
Schizophrenia (2014)	0.8	1.8	4.8	2.2	0.3	0.7	0.5	2.1	1.6	1.7	1.6	1.8	-0.2	1.3	1.0	0.1	-0.2	1.4	2.1	0.0
Heel T-Score	0.8	6.3	12.5	2.1	3.5	-0.4	1.4	3.0	3.0	2.3	2.3	2.8	2.0	3.1	3.5	-0.8	-0.5	2.8	2.6	3.1
Type 2 Diabetes (T2D) (2018)	0.8	1.6	7.6	-0.6	-1.8	0.4	-2.8	-1.3	-1.2	-0.3	-1.2	-1.0	-1.1	-1.2	-1.0	0.5	1.6	-1.0	-1.0	-1.2
Loneliness, isolation	0.8	1.0	7.4	1.6	0.1	-0.7	-0.4	0.9	0.7	0.4	1.0	0.7	0.6	0.9	0.4	0.6	2.7	0.9	1.1	0.6
Medication: Gliclazide	0.8	0.9	3.5	-0.0	-1.4	0.3	-0.6	-1.0	-0.7	0.0	-0.7	-0.5	-0.2	-0.9	-1.5	1.7	1.9	-0.7	-0.5	-0.8
Commuting to job workplace: Public transport	0.8	0.9	4.1	1.2	-1.9	-0.4	-0.4	-0.3	-0.5	-2.0	-0.1	-0.6	-0.5	-0.1	-1.9	-0.9	-0.7	-0.4	-0.2	-0.6
Fractured/broken bones in last 5 years	0.8	1.0	2.5	-1.6	-0.8	-0.7	1.5	-0.8	-1.2	0.1	-1.3	-1.3	-0.5	-1.0	0.1	0.7	-0.2	-1.1	-1.2	-1.2
Impedance of whole body	0.8	4.1	10.8	-3.2	3.3	-1.3	2.7	-1.4	-1.5	2.5	-2.5	-1.5	0.8	-1.8	-0.2	2.3	-1.6	-1.7	-2.0	-1.4
Ovarian Cancer	0.7	1.0	5.9	-1.2	-2.4	1.5	-1.3	-1.0	-0.4	-1.2	-0.0	-0.4	0.3	-0.6	0.1	-0.7	0.8	-0.0	-0.7	-0.4
Ulcerative Colitis	0.7	1.0	8.2	-0.5	0.4	-0.5	0.7	1.1	0.1	2.9	0.0	0.2	0.3	0.2	1.1	2.3	0.4	-0.0	0.6	0.0
Allergy or Eczema	0.7	1.8	7.3	-1.3	-2.6	-0.9	-2.7	-1.5	-0.7	-1.7	-0.5	-0.7	-0.6	-0.4	-0.5	-1.7	1.6	-0.1	-0.9	-0.7
Relative age of first facial hair	0.7	1.4	3.3	0.2	-0.1	-1.0	0.2	1.0	1.7	0.1	1.1	1.8	0.4	1.6	1.6	-1.8	0.4	1.7	1.1	1.7
Impedance of leg (right)	0.7	3.4	23.1	-1.9	4.8	-0.8	2.4	0.2	-0.0	3.3	-1.4	0.0	0.5	-0.5	1.3	3.0	-0.5	-0.3	-0.4	0.1
Trunk fat percentage	0.7	2.8	17.4	1.1	-4.2	0.0	-2.9	0.3	1.1	-1.4	1.4	1.2	0.3	1.7	0.4	-1.9	1.8	1.4	0.9	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	3.2	1.0	-0.5	-1.4	0.5	1.7	0.4	-0.6	1.5	0.5	0.1	0.5	0.6	0.5	1.8	0.5	1.4	0.4
Trunk fat mass	0.7	3.1	23.1	1.2	-4.8	0.5	-3.0	-0.2	0.9	-1.9	1.1	1.0	0.2	1.5	0.0	-2.1	1.6	1.2	0.6	0.7
Nervous feelings	0.7	1.3	6.6	1.3	-0.1	-0.7	0.3	1.3	0.8	0.7	1.4	0.7	-0.4	1.1	0.4	1.8	2.6	0.8	1.2	0.8
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.6	-1.4	-0.8	0.2	-0.4	-0.7	-0.9	-1.4	-0.4	-0.9	-1.6	-1.0	-0.0	-1.2	1.0	-0.8	-0.7	-0.9
Illnesses of siblings	0.7	0.9	3.1	-0.6	0.0	-1.2	0.9	-0.5	-1.0	-0.7	-1.4	-1.1	-0.2	-0.9	-1.1	0.6	-1.8	-1.2	-0.8	-1.0
Weight	0.7	3.3	29.5	0.7	-5.4	0.8	-2.8	-0.8	0.2	-2.9	0.7	0.4	-0.2	0.8	-0.3	-2.2	1.4	0.6	-0.1	0.1
Impedance of arm (left)	0.7	3.3	11.5	-3.4	1.5	-0.9	1.9	-1.7	-1.8	1.5	-2.4	-1.8	0.3	-2.0	-0.4	1.5	-1.6	-1.8	-2.3	-1.7
Peak expiratory flow (PEF)	0.7	1.6	6.2	0.4	2.5	-0.7	2.2	-0.8	-0.3	2.1	-1.5	-0.2	-0.1	-0.3	-0.5	2.4	0.6	-0.6	-0.8	-0.3
Wheeze or whistling in the chest in last year	0.7	1.3	8.5	0.8	-2.1	-0.0	-2.9	0.5	0.7	-1.0	0.9	0.7	-0.5	0.5	0.6	-1.1	1.2	0.8	0.6	0.7
Suffer from ‘nerves’	0.7	1.1	6.1	1.8	0.3	0.8	0.3	0.9	0.7	0.6	1.0	0.6	-0.6	0.6	0.1	1.4	2.5	0.8	0.9	0.8
Age at last live birth	0.7	1.0	2.4	-0.8	-0.5	0.8	-0.4	-1.4	-0.9	-1.5	-1.1	-1.0	-1.1	-0.8	-0.8	-1.4	-0.9	-0.9	-1.2	-0.9
Leg fat-free mass (right)	0.7	3.8	31.5	0.1	-5.6	1.0	-2.1	-1.6	-1.0	-3.2	-0.4	-1.0	-0.7	-0.5	-1.5	-2.6	0.1	-0.6	-1.1	-1.1
Diabetes diagnosed by doctor	0.7	1.1	4.7	0.1	-2.0	-0.1	-2.2	-0.7	-0.9	-0.6	-0.7	-0.6	-1.4	-0.8	-1.1	0.4	1.3	-0.8	-0.3	-0.9
Smoking status: Current	0.7	1.1	9.9	0.6	1.3	1.0	3.1	-0.6	-0.2	0.9	-0.1	-0.2	2.0	-0.0	-0.7	0.2	-0.3	-0.1	-0.4	-0.2
Leg predicted mass (right)	0.7	3.7	31.0	0.0	-5.6	1.0	-2.0	-1.7	-1.0	-3.1	-0.5	-1.0	-0.7	-0.6	-1.6	-2.5	0.1	-0.7	-1.2	-1.2
Breast Cancer	0.6	1.5	3.8	-1.5	0.0	-0.8	-0.5	-2.0	-1.3	-0.5	-1.7	-1.2	-1.4	-1.3	-1.6	-0.5	0.6	-1.2	-1.4	-1.4
Body Mass Index (BMI) (2010)	0.6	0.8	6.2	0.5	-2.5	-0.6	-1.8	0.5	0.2	-1.4	0.6	0.2	-0.2	0.2	0.9	-0.2	0.7	0.3	0.3	0.2
Primary Biliary Cirrhosis	0.6	0.9	2.9	-0.9	0.3	0.7	0.7	-0.3	-1.0	-0.1	-0.6	-0.9	-1.7	-1.0	-0.9	0.3	-1.4	-1.2	-0.9	-0.9
Respiratory disease	0.6	1.3	2.4	1.5	-0.5	-0.8	-1.3	0.9	1.4	-0.5	1.3	1.6	0.0	1.5	0.0	-1.5	-0.5	1.4	1.2	1.4
Ever had hysterectomy (womb removed)	0.6	0.7	2.6	-0.3	-0.1	-1.1	1.6	0.5	0.6	0.7	0.6	0.6	1.6	0.5	1.4	0.0	0.6	0.7	0.8	0.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.7	0.4	-0.6	1.6	-0.5	0.7	0.8	-1.3	0.3	0.9	-0.0	0.5	0.8	0.4	1.4	0.7	0.7	0.8
Medication for hormone replacement therapy	0.6	0.7	3.1	-0.5	-0.3	0.3	-0.2	-0.5	-0.8	-0.8	-1.1	-1.0	-0.6	-0.8	-0.5	1.8	1.3	-0.8	-0.7	-0.8
Medication: Co-codamol	0.6	0.7	4.4	-0.5	-2.1	-1.4	-1.0	-0.6	-0.1	-0.2	-0.2	-0.1	-1.3	0.1	-0.9	-0.7	-0.0	0.1	-0.1	-0.2
Leg fat-free mass (left)	0.6	3.2	30.1	0.3	-5.5	0.9	-2.1	-1.2	-0.6	-2.9	-0.0	-0.6	-0.7	-0.1	-1.0	-2.2	0.5	-0.3	-0.8	-0.7
Current tobacco smoking	0.6	1.0	8.8	0.2	1.4	0.8	3.0	-0.7	-0.3	0.7	-0.2	-0.2	1.7	-0.0	-0.5	0.2	-0.2	-0.1	-0.5	-0.3
Impedance of leg (left)	0.6	3.1	21.3	-2.0	4.6	-1.0	2.5	-0.3	-0.3	2.9	-1.7	-0.2	0.8	-0.7	0.8	2.2	-0.7	-0.6	-0.7	-0.2
Leg predicted mass (left)	0.6	3.2	30.2	0.2	-5.5	0.9	-2.1	-1.2	-0.6	-2.9	-0.1	-0.6	-0.7	-0.2	-1.1	-2.3	0.4	-0.3	-0.8	-0.7
Hip circumference	0.6	2.7	23.3	0.5	-4.8	0.8	-2.6	-0.4	0.3	-2.4	0.9	0.4	-0.3	0.8	-0.2	-1.8	1.9	0.7	0.3	0.2
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	7.4	-0.7	2.0	-0.4	2.7	-1.4	-1.0	1.7	-2.4	-1.0	-0.1	-1.3	-0.5	0.8	-0.7	-1.2	-1.6	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.1	6.5	-1.3	1.0	0.1	2.4	-1.5	-1.4	0.8	-2.5	-1.4	-0.1	-1.7	-0.9	0.7	-1.1	-1.6	-1.8	-1.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.2	0.8	-1.4	-1.1	-0.9	-0.3	-0.4	1.1	0.0	-0.4	-1.0	-0.0	-1.4	0.1	1.5	-0.4	0.2	-0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	5.6	-0.7	-0.5	2.4	0.0	-0.6	-0.3	0.5	-1.2	-0.6	-1.1	-0.6	-0.2	1.1	-0.2	-0.5	-0.5	-0.3
Number of children fathered	0.6	0.7	4.9	-2.2	1.1	-0.0	-0.3	-0.8	-0.4	0.8	-0.7	-0.4	0.6	-0.1	0.6	0.9	-0.3	-0.3	-0.9	-0.3
Age at first live birth	0.6	1.1	3.0	-1.7	-0.6	0.3	-1.5	-1.3	-0.9	-0.6	-1.4	-0.9	-1.3	-0.9	0.3	-0.9	-1.0	-0.8	-1.4	-0.8
Comparative height size at age 10	0.6	3.3	8.0	-2.1	-1.9	-0.0	1.4	-2.6	-2.0	-1.0	-2.3	-2.0	0.4	-1.6	-1.2	-0.4	-2.1	-1.9	-2.8	-2.0
Illnesses of father: Heart disease	0.6	0.9	3.1	1.2	-1.4	-0.3	-1.8	0.2	0.8	-0.2	1.3	0.9	0.5	0.9	-0.4	-1.2	0.7	1.0	0.7	0.7
Average weekly red wine intake	0.6	0.8	3.5	-1.4	-1.2	-0.8	-1.9	-1.0	-0.7	0.7	-0.6	-0.7	-1.0	-0.6	-0.1	0.7	0.1	-0.6	-1.1	-0.6
Osteoporosis (self-reported)	0.6	0.8	1.8	-0.6	-0.7	1.3	-0.5	-1.0	-0.9	0.7	-0.8	-1.1	-0.7	-1.3	-0.6	-0.5	-0.5	-0.8	-1.2	-1.0
Medication: Aspirin	0.6	0.7	3.9	2.0	0.4	1.2	-1.2	0.3	0.5	-0.5	1.1	0.6	0.6	0.6	-0.5	-0.3	0.7	0.7	0.7	0.5
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.7	0.9	-0.4	-1.0	-0.8	1.3	0.8	-0.6	0.6	0.8	-0.5	0.8	1.3	0.9	1.3	0.8	0.9	0.8
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.5	-1.3	-1.6	-1.2	-1.1	-0.3	-0.2	-1.4	-0.1	-0.3	-1.5	-0.0	0.3	-0.7	-0.3	-0.2	-0.0	-0.3
Unable to work because of sickness or disability	0.6	0.7	1.8	1.2	-0.8	-1.1	-0.9	0.4	0.7	1.4	1.0	0.7	0.6	0.9	-0.1	1.0	0.9	0.9	0.5	0.7
Alcohol drinker status: Previous	0.6	0.7	3.1	0.5	0.6	-1.8	0.0	1.6	0.3	0.1	0.3	0.1	-1.7	0.3	0.9	-0.6	-0.2	0.1	0.8	0.3
Pack years of smoking	0.6	0.9	2.3	1.2	0.2	1.2	-0.7	0.6	1.0	-1.5	0.9	0.8	0.7	1.2	0.6	-0.4	1.3	1.0	1.0	0.9
Depressed Affect (Nagel 2018)	0.5	1.0	7.8	1.1	-0.3	-0.1	-0.2	1.0	0.5	0.9	1.5	0.5	-0.3	0.9	0.4	0.6	2.8	0.7	1.4	0.4
Worry (Nagel 2018)	0.5	1.0	5.5	1.6	-0.7	-0.6	0.1	1.0	0.4	0.9	1.0	0.4	-0.6	0.6	-0.2	1.8	2.3	0.5	0.9	0.4
Alzheimer’s Disease (including proxy)	0.5	0.7	3.3	0.1	-1.8	1.0	-1.4	-0.2	-0.8	0.0	0.6	-0.6	-0.7	-0.9	-0.4	-1.1	0.2	-0.5	-0.5	-0.8
Mean Putamen Volume	0.5	0.6	2.9	-1.3	0.6	0.8	0.1	-0.5	-0.4	-0.5	-0.1	-0.4	-0.3	-0.5	1.1	-1.2	-1.7	-0.3	-0.5	-0.3
Rheumatoid Arthritis	0.5	0.7	3.2	0.2	1.4	-1.8	1.2	0.8	0.6	1.0	0.4	0.6	0.0	0.6	0.5	-0.2	0.1	0.4	0.9	0.6
Hand grip strength (left)	0.5	1.2	3.4	-1.6	1.2	-0.2	1.3	-1.5	-0.9	-0.2	-1.7	-0.7	-0.1	-1.1	0.0	-0.2	-1.8	-1.1	-1.7	-0.8
Sensitivity / hurt feelings	0.5	0.8	3.2	-0.5	1.3	-0.4	0.5	0.9	0.9	0.1	0.9	0.8	0.1	1.0	1.8	0.5	0.8	1.0	0.9	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.9	0.4	0.3	-1.4	1.1	0.6	0.0	0.4	0.8	0.1	0.1	0.2	0.5	1.6	2.0	0.1	0.6	0.0
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.9	0.4	-1.1	1.4	-0.4	0.4	0.9	1.2	0.7	0.8	0.1	0.7	0.8	0.9	0.8	1.0	0.7	0.9
Supplements: Zinc	0.5	0.5	3.3	-0.7	0.6	-0.4	1.8	-0.7	-0.1	1.4	-0.0	-0.1	0.8	0.0	-0.4	0.9	-0.6	-0.0	-0.4	-0.1
Supplements: Glucosamine	0.5	0.6	1.9	0.2	0.4	1.4	0.1	0.8	0.9	0.0	1.3	0.8	-0.3	0.5	1.1	-0.1	0.5	0.9	1.0	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.6	1.3	0.8	-1.1	0.7	0.9	0.5	0.7	1.3	0.6	0.9	0.6	0.4	0.5	1.6	0.6	1.2	0.4
Had menopause	0.5	0.6	2.6	0.6	0.5	0.1	0.3	0.2	0.7	0.1	0.7	0.7	1.6	1.0	1.0	-1.0	-1.4	0.7	0.3	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.4	0.9	0.3	-0.9	-0.3	0.8	1.5	0.2	1.3	1.3	0.4	1.5	1.2	-1.1	0.1	1.5	0.9	1.6
Mouth/teeth dental problems	0.5	0.7	3.5	0.2	1.8	-0.5	1.9	0.4	0.2	1.5	0.3	0.2	1.4	0.3	-0.1	0.3	-0.2	0.2	0.3	0.2
Pain all over the body in last month	0.5	0.5	1.9	0.6	0.8	-1.4	1.1	-0.2	0.5	0.8	0.0	0.5	-0.6	1.2	0.2	0.0	0.9	0.5	0.2	0.5
Time employed in main current job	0.5	0.6	2.4	0.2	-0.5	-1.1	-1.1	-0.7	-0.1	0.4	-0.6	-0.1	-1.6	0.4	-1.0	-1.4	-1.0	-0.1	-0.3	-0.2
Father’s age at death	0.5	0.7	3.3	0.1	0.2	-1.3	0.5	-0.4	-0.8	-0.3	-1.3	-0.7	0.3	-0.6	-1.3	1.8	-0.5	-1.0	-0.5	-0.8
Falls in the last year	0.5	0.6	2.5	0.4	-0.3	-0.7	0.5	0.9	0.8	1.6	0.6	0.8	-1.0	0.8	0.3	0.9	0.8	0.6	0.9	0.8
Exposure to tobacco smoke at home	0.5	0.6	1.1	-0.3	-0.7	1.0	-1.0	-0.6	-0.9	-0.1	-0.8	-1.0	0.6	-1.0	-0.1	-0.7	0.3	-0.9	-0.8	-0.8
Hair/balding pattern: Pattern 4	0.5	1.1	6.6	-0.9	0.6	-0.4	-0.2	-0.6	-0.3	-1.7	-0.9	-0.3	-1.7	-0.2	0.4	-1.6	-2.6	-0.5	-0.8	-0.2
Birth weight of first child	0.5	0.9	5.3	-0.4	-0.7	-2.3	1.0	-0.7	-0.5	-0.3	-1.2	-0.4	-0.4	-0.5	-0.7	-1.1	-1.7	-0.7	-0.4	-0.5
Glaucoma (self-reported)	0.5	0.6	2.2	0.3	0.2	-1.1	-1.3	0.1	0.6	0.7	0.8	0.6	-0.7	1.1	0.3	1.5	1.1	0.6	0.5	0.6
Gout (self-reported)	0.5	0.7	3.6	-0.4	-1.6	0.1	-1.5	-0.0	0.3	-1.0	0.7	0.2	-1.2	0.2	-0.0	-1.9	0.7	0.5	0.3	0.2
Medication: Allopurinol	0.5	0.6	2.7	-0.6	-1.6	-0.2	-1.2	-0.7	-0.2	-1.0	-0.0	-0.3	-1.3	-0.1	-0.3	-1.5	0.3	-0.0	-0.3	-0.3
Family relationship satisfaction	0.5	0.6	3.1	0.6	1.2	1.8	0.8	0.8	0.0	-0.5	0.5	-0.0	0.9	-0.8	0.6	0.0	0.6	-0.0	0.6	-0.0
Leg pain on walking	0.5	0.7	2.5	0.7	-0.6	0.0	-1.2	0.6	0.8	0.4	1.6	0.8	-0.1	0.8	1.1	-0.3	0.9	0.9	0.8	0.8
Medication: Aspirin	0.5	0.6	3.7	1.9	-0.0	1.6	-1.1	-0.0	0.0	-0.7	0.9	0.1	0.5	0.1	-0.9	-0.0	0.6	0.2	0.4	0.0
Ever had bowel cancer screening	0.5	0.6	1.7	-0.4	0.2	-1.1	-1.3	0.4	0.9	0.2	0.4	0.9	1.3	0.9	0.5	0.7	-0.0	1.0	0.7	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.5	1.9	0.0	0.1	-0.4	0.1	0.7	0.7	0.7	0.7	0.8	0.9	-0.5	-0.4	1.2	0.9	0.7	0.6
Eye problems/disorders: Glaucoma	0.5	0.6	3.3	-0.9	0.5	0.0	-1.3	-0.7	-0.6	0.7	-0.5	-0.6	-1.8	-0.3	-0.0	1.2	0.4	-0.7	-0.7	-0.6
Basal metabolic rate	0.5	2.5	22.6	0.3	-4.8	1.0	-1.8	-1.2	-0.4	-2.6	-0.1	-0.4	-0.6	-0.1	-0.9	-2.1	0.5	-0.2	-0.7	-0.6
Number of operations (self-reported)	0.5	0.7	1.7	1.3	0.4	0.1	-0.3	0.7	1.0	0.6	0.8	1.0	0.0	1.3	1.1	-0.2	1.2	1.0	0.8	0.9
Basal cell carcinoma (self-reported)	0.5	0.6	2.4	1.5	0.9	-0.7	0.9	0.8	0.6	0.2	0.8	0.3	0.1	0.6	0.3	0.8	1.2	0.5	0.6	0.6
Bipolar Disorder or Schizophrenia	0.4	0.9	2.3	1.5	0.9	1.1	-0.3	1.4	0.9	1.3	0.6	1.0	-0.8	0.7	0.7	1.1	-0.6	0.7	1.3	0.0
Crohns Disease (2017)	0.4	0.9	1.7	0.6	-0.2	0.9	0.1	1.2	1.2	1.0	1.2	1.3	0.9	0.9	1.3	-0.1	0.1	1.3	1.0	1.3
Triglycerides	0.4	0.6	1.6	0.2	-1.2	-0.8	-0.8	-0.4	-1.1	-0.8	-0.5	-1.1	-0.4	-1.0	-0.6	-0.4	-0.5	-1.0	-0.8	-1.0
Blood Platelet Count	0.4	5.2	14.1	2.5	3.8	3.0	1.4	2.0	2.5	2.0	3.0	2.3	1.3	2.1	1.7	0.7	0.9	2.5	2.3	2.5
Blood White Count	0.4	3.1	6.1	2.1	1.6	-2.5	-1.2	1.4	1.8	-0.2	2.5	2.0	-0.9	2.1	1.5	-2.1	0.7	1.8	2.2	1.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	2.1	-0.0	0.2	-0.8	1.0	0.2	0.9	-0.0	0.7	0.9	-0.2	0.9	0.7	-0.6	-1.5	0.7	0.2	0.9
Hayfever, allergic rhinitis or eczema	0.4	0.9	4.4	-0.2	-2.0	-0.4	-2.1	-0.7	-0.1	-0.5	-0.1	-0.2	-1.3	0.1	-0.4	-0.6	1.7	0.2	-0.3	-0.2
Number of incorrect matches in round	0.4	0.6	2.2	0.4	0.1	-0.8	0.8	0.4	1.1	0.3	0.6	1.0	1.5	0.9	0.5	0.3	0.3	1.0	0.6	1.0
Allergy	0.4	0.9	5.2	-0.6	2.3	-0.1	2.1	0.1	-0.5	0.6	-0.4	-0.6	0.9	-0.6	0.5	0.7	-1.4	-0.7	-0.3	-0.4
Pulse rate	0.4	0.7	1.6	-1.1	-1.2	-1.3	-0.5	-1.2	-0.6	-1.0	-0.9	-0.5	-1.0	-0.2	-0.8	-0.7	-1.0	-0.5	-0.8	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.9	0.6	0.9	0.7	0.5	-0.6	-0.7	-0.3	-0.6	-0.7	-0.6	-0.9	-0.8	0.4	-0.5	-0.8	-1.0	-0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	3.0	0.4	-0.4	0.8	-1.7	0.5	0.7	-0.5	1.2	0.9	-0.3	0.5	1.2	-0.5	1.1	0.9	0.8	0.7
Asthma	0.4	0.8	4.0	0.9	-1.2	-0.4	-2.0	0.3	0.8	-0.3	0.9	1.0	-0.9	0.8	-0.3	-1.3	-0.1	0.9	0.6	0.8
Medication: Paracetamol	0.4	0.6	3.6	0.9	1.2	-0.1	1.9	0.6	0.7	0.3	0.5	0.7	0.3	0.6	0.8	-0.7	-0.3	0.7	0.2	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.9	0.5	0.2	0.8	-1.3	0.2	1.0	0.3	1.4	1.1	0.7	1.1	1.1	0.0	0.4	1.2	0.6	1.0
Arm fat-free mass (right)	0.4	2.1	16.8	0.7	-4.1	1.3	-1.3	-1.0	-0.4	-2.5	-0.2	-0.4	-0.5	-0.1	-0.9	-2.5	-0.1	-0.2	-0.6	-0.5
Exposure to tobacco smoke outside home	0.4	0.5	2.9	0.6	-0.6	1.4	-0.1	-0.1	0.4	1.2	0.1	0.3	0.4	0.2	-0.3	0.6	1.7	0.4	0.5	0.3
Neck or shoulder pain in last month	0.4	0.5	3.2	-0.0	-1.0	0.2	0.4	0.5	0.1	-1.8	0.1	0.2	-0.1	0.1	0.1	-1.8	-0.8	0.1	0.1	0.1
Arm predicted mass (right)	0.4	2.1	17.2	0.7	-4.2	1.2	-1.6	-0.9	-0.3	-2.4	-0.1	-0.2	-0.6	0.0	-0.8	-2.4	0.3	-0.1	-0.5	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.1	-1.4	-0.2	0.3	-1.2	-0.4	-0.4	-0.6	-0.8	-0.3	-1.8	-0.3	0.1	0.5	0.3	-0.5	-0.3	-0.4
Illnesses of siblings: Diabetes	0.4	0.5	3.0	-0.3	-1.1	-0.1	-1.7	-0.5	-0.6	-1.4	-0.1	-0.4	0.2	-0.5	-0.6	-0.3	0.8	-0.5	-0.5	-0.6
Whole body fat-free mass	0.4	2.4	18.2	0.1	-4.3	1.1	-1.3	-1.4	-0.8	-2.6	-0.6	-0.9	-0.7	-0.5	-1.2	-2.1	0.0	-0.6	-1.1	-0.9
Friendships satisfaction	0.4	0.5	3.8	0.8	0.4	0.5	-0.7	-0.1	-0.5	-2.0	-0.2	-0.5	-0.1	-0.4	-0.7	-0.4	-0.9	-0.5	-0.1	-0.6
Whole body water mass	0.4	2.4	18.9	0.2	-4.3	1.2	-1.4	-1.3	-0.7	-2.7	-0.4	-0.7	-0.7	-0.4	-1.1	-2.2	0.1	-0.5	-0.9	-0.8
Medication: Paracetamol	0.4	0.7	2.6	1.0	0.7	0.8	1.6	0.7	0.7	-0.4	0.7	0.8	0.1	0.3	0.7	-1.5	-0.8	0.7	0.2	0.8
Medication: Atorvastatin	0.4	0.5	3.5	0.8	0.1	0.5	-1.9	-0.2	0.3	-1.0	0.3	0.4	-0.5	0.4	-0.5	0.6	1.5	0.3	0.2	0.3
Arm fat-free mass (left)	0.4	1.9	16.2	0.6	-4.0	1.2	-1.4	-0.8	-0.1	-2.5	0.2	-0.0	-0.4	0.3	-0.5	-1.8	0.8	0.1	-0.3	-0.2
Average weekly beer plus cider intake	0.4	0.5	1.8	-0.6	0.2	0.4	1.4	-0.6	-0.6	-1.0	-0.7	-0.7	0.5	-0.7	-0.7	-0.3	-0.9	-0.7	-0.9	-0.5
Supplements: Calcium	0.4	0.4	1.9	-0.9	-0.9	0.4	0.9	-0.5	-0.1	0.7	-0.4	-0.2	-0.7	0.0	-0.1	1.1	-1.4	-0.1	-0.4	-0.0
Depression (Nagel 2018)	0.3	0.4	3.3	0.3	0.3	-0.8	0.7	0.3	-0.3	0.3	0.2	-0.2	0.2	-0.4	-0.3	1.8	1.4	-0.3	0.3	-0.3
Ulcerative Colitis (UC)	0.3	0.5	3.7	-1.0	-0.7	0.0	-0.6	-0.2	-0.4	1.9	-0.5	-0.2	0.2	-0.3	0.6	1.2	-0.2	-0.3	-0.6	-0.2
Age at First Birth	0.3	0.4	3.2	0.4	0.3	-0.6	0.3	-0.0	0.1	1.6	-0.1	-0.1	0.1	0.1	0.4	1.8	0.7	-0.1	-0.2	0.1
LDL Cholesterol	0.3	0.4	2.3	-1.5	0.2	0.3	0.4	-0.4	-0.1	0.3	-0.3	-0.1	1.2	-0.2	0.8	-0.1	-1.5	-0.0	-0.5	-0.0
Severe depression (siblings)	0.3	0.3	1.3	-0.4	0.7	-1.1	0.6	-0.2	-0.4	-0.5	0.0	-0.3	-0.2	0.1	-0.4	-1.1	-0.8	-0.4	-0.3	-0.4
Pack years adult smoking proportion	0.3	0.5	2.0	0.8	0.3	1.4	-0.4	0.4	0.7	-0.9	0.4	0.5	0.9	0.9	0.3	0.0	1.1	0.7	0.6	0.7
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.9	-0.1	-0.9	-1.4	0.3	-0.0	-0.0	0.7	0.2	0.1	0.3	0.1	0.5	1.0	1.0	0.1	0.1	-0.1
Stomach or abdominal pain in last month	0.3	0.4	2.1	0.5	0.3	-0.7	1.2	0.2	0.2	-0.4	0.2	0.3	0.2	0.6	0.4	-1.4	-0.9	0.2	-0.0	0.3
Chronic bronchitis/emphysema (father)	0.3	0.3	2.5	-0.2	0.5	1.6	-0.8	0.5	0.2	-0.5	0.5	0.3	-0.3	-0.3	0.5	-0.1	0.7	0.2	0.4	0.2
Alcohol usually taken with meals	0.3	0.5	1.8	-1.1	0.0	-0.8	-1.3	-0.5	-0.6	-0.5	-1.1	-0.7	-0.4	-0.4	-0.0	0.9	-0.0	-0.8	-0.7	-0.6
Hearing difficulty/problems with background noise	0.3	0.5	2.7	0.4	-1.6	0.4	-0.3	0.6	0.5	-0.3	0.9	0.5	-0.1	0.5	0.4	0.7	1.1	0.6	0.5	0.5
Hair/balding pattern: Pattern 2	0.3	0.4	1.8	0.7	-1.3	0.8	-0.4	0.4	-0.2	0.8	0.6	-0.1	-0.4	-0.1	-0.2	0.9	1.3	-0.1	0.4	-0.2
Trunk fat-free mass	0.3	1.9	10.4	-0.1	-3.2	1.1	-0.7	-1.6	-1.0	-2.3	-1.0	-1.0	-0.9	-0.8	-1.2	-1.6	-0.2	-0.9	-1.2	-1.1
Trunk predicted mass	0.3	1.8	10.4	-0.1	-3.2	1.1	-0.6	-1.5	-0.9	-2.3	-0.9	-0.9	-0.9	-0.7	-1.1	-1.6	-0.2	-0.8	-1.2	-1.0
Tense / ‘highly strung’	0.3	0.5	1.7	0.3	-1.3	-0.8	-0.0	-0.1	-0.2	1.3	0.4	-0.1	-1.2	-0.0	-0.3	0.6	1.3	-0.0	0.3	-0.2
Blood clot in the leg (DVT)	0.3	0.4	3.1	-0.0	-0.3	-0.3	0.3	0.7	-0.3	-1.8	-0.1	-0.3	0.6	-0.8	-0.2	0.6	-0.8	-0.5	-0.0	-0.3
Number of full brothers	0.3	0.3	2.2	0.1	0.2	-0.1	0.2	0.2	-0.1	-0.8	0.2	-0.0	-1.1	-0.3	-0.6	-1.5	-0.9	-0.1	-0.2	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.3	0.2	0.6	-0.5	1.5	0.5	0.3	1.2	0.7	0.3	0.2	0.4	0.4	0.8	0.7	0.4	0.7	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.1	1.5	0.2	-0.3	-0.8	-0.1	0.5	-0.5	0.5	0.5	0.5	0.6	-0.6	0.7	0.5	0.4	0.3	0.5
Chest pain or discomfort	0.3	0.4	3.1	0.3	-0.4	-1.8	0.1	0.2	0.4	-0.4	0.7	0.5	1.2	0.6	-0.0	-0.4	-0.5	0.4	0.1	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.8	0.2	0.0	0.8	0.6	0.7	0.3	0.1	0.9	0.2	0.6	0.3	0.6	1.7	0.6	0.4	0.5	0.3
Asthma (self-reported)	0.3	0.7	2.4	0.7	-1.2	-0.6	-1.6	0.3	0.8	-0.2	0.8	1.0	-0.9	0.7	-0.1	-1.2	-0.1	0.9	0.5	0.9
Osteoarthritis (self-reported)	0.3	0.4	1.8	-0.8	-1.3	0.7	-1.1	-0.4	-0.2	-0.8	0.2	-0.2	0.5	-0.3	0.1	-1.1	-0.1	0.1	-0.4	-0.3
Hearing aid user	0.3	0.3	0.9	-0.9	-0.4	-0.2	-0.7	-0.8	-0.5	-0.5	0.0	-0.5	-0.6	-0.5	0.4	0.5	0.3	-0.4	-0.7	-0.5
Risk taking	0.3	0.4	1.6	-1.1	-0.8	0.6	-0.3	0.3	0.1	1.1	-0.4	0.1	-1.2	-0.3	0.6	1.0	0.2	0.1	0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.9	0.2	-0.4	-0.9	0.3	1.1	0.2	-1.4	0.4	0.2	0.5	-0.2	0.3	0.4	-0.5	-0.0	0.4	0.2
Arm predicted mass (left)	0.3	1.7	16.1	0.6	-4.0	1.0	-1.4	-0.9	-0.1	-2.3	0.2	-0.1	-0.4	0.3	-0.7	-1.6	0.5	0.1	-0.3	-0.2
Bipolar Disorder (2018)	0.2	0.4	1.4	-0.7	1.0	0.0	0.3	-0.4	-0.5	-0.6	-0.6	-0.5	-0.1	-0.6	-0.2	1.2	-0.9	-0.6	-0.5	0.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.8	-1.1	0.5	0.1	1.7	-0.3	-0.8	-1.6	-0.5	-1.0	0.7	-0.8	0.3	-0.8	-0.6	-0.7	-0.8	-0.9
Irritable Bowel Disease (IBD)	0.2	0.5	4.6	-0.3	-0.3	0.7	-0.1	0.5	0.3	2.1	0.2	0.4	0.8	0.1	1.0	0.9	-0.6	0.3	-0.0	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.8	0.1	0.4	-0.4	1.3	-0.0	0.2	-1.2	0.1	0.0	1.3	0.5	0.7	-0.3	-0.3	0.3	-0.3	0.2
Crohns Disease (2012)	0.2	0.3	2.3	0.1	-1.5	0.0	-0.1	0.1	0.6	0.7	0.1	0.6	0.5	0.0	0.1	0.2	0.8	0.6	0.1	0.0
Lung FEV1/FVC ratio	0.2	1.1	3.8	0.5	1.9	1.7	-0.2	0.2	0.7	1.9	-0.4	0.4	-1.0	0.7	0.4	1.9	1.2	0.6	0.2	0.7
Lung FVC	0.2	1.1	6.1	1.3	1.7	-1.0	2.5	-0.2	-0.6	1.0	-1.3	-0.7	1.0	-0.7	-0.9	0.1	-0.8	-0.8	-0.4	-0.6
Tanning	0.2	2.2	15.4	-0.3	3.2	0.3	3.9	1.0	0.7	1.9	-0.5	0.4	0.3	0.2	0.7	0.7	-2.0	0.3	0.5	0.8
Hearing difficulty/problems: Yes	0.2	0.4	2.2	-0.5	-1.5	0.3	-0.7	-0.0	-0.5	-0.8	0.1	-0.5	-0.7	-0.4	0.5	0.4	0.5	-0.5	-0.6	-0.4
Diabetes (father)	0.2	0.3	1.3	0.3	0.1	-0.9	-0.4	0.2	0.3	-1.1	0.5	0.2	0.3	0.3	0.8	-1.1	-0.2	0.4	-0.1	0.4
Relative age voice broke	0.2	0.3	1.1	-1.0	-0.9	0.2	-0.5	-1.0	0.2	0.3	-0.6	0.3	0.6	-0.0	-0.2	0.5	0.6	0.3	-0.8	0.1
Qualifications: CSEs or equivalent	0.2	0.2	1.0	0.1	0.1	0.4	0.4	-0.3	-0.3	0.7	-0.5	-0.5	-1.0	-0.2	-0.9	0.3	-0.1	-0.4	-0.3	-0.3
Medication: Levothyroxine sodium	0.2	0.4	1.6	0.7	-0.9	0.7	-1.3	-0.5	0.2	-0.7	0.8	0.3	0.4	0.4	-0.4	-1.0	-0.2	0.5	0.0	0.2
Had other major operations	0.2	0.3	2.2	-0.3	-0.3	-1.0	-0.0	0.2	-0.1	-0.9	0.1	-0.2	-0.6	-0.1	0.4	-1.5	-0.0	-0.1	0.2	-0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	4.7	0.0	0.3	-0.9	0.4	-0.3	-0.4	-0.8	-0.9	-0.5	-0.5	-0.1	-0.4	2.2	0.5	-0.5	-0.4	-0.4
Headache pain in last month	0.2	0.3	1.8	0.1	0.5	-0.6	1.4	-0.4	-0.1	1.3	-0.1	0.1	0.2	-0.2	-0.2	0.4	-0.0	-0.1	-0.4	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.6	-0.5	-1.3	-0.9	-0.2	0.0	0.0	0.3	-0.2	-0.1	-0.0	0.3	0.1	-0.1	-1.2	0.0	-0.2	0.1
Birth weight	0.2	0.5	2.3	0.1	-1.3	0.3	0.3	-1.2	-0.5	-1.5	-0.7	-0.4	-0.1	-0.5	-0.9	0.3	-0.4	-0.5	-0.9	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	-0.5	1.1	-0.9	-0.5	0.1	-0.4	-0.7	-0.3	-0.3	0.3	-0.3	0.5	-0.0	0.3	-0.3	0.1	-0.4
Qualifications: College or University degree	0.2	0.7	3.9	-1.2	0.4	-0.2	0.9	-0.4	-0.0	-1.2	-0.5	-0.1	1.1	0.0	1.0	-0.6	-2.0	-0.1	-0.5	-0.0
Medication for pain relief, constipation, heartburn	0.2	0.4	2.8	-1.7	0.1	-0.2	-0.3	-0.4	-0.4	0.4	-0.7	-0.5	-0.1	-0.6	0.3	0.0	-1.1	-0.4	-0.4	-0.3
Pulse rate, automated reading	0.2	0.7	2.5	-0.9	-0.4	0.6	1.3	-0.8	-0.9	0.7	-1.0	-0.8	-0.3	-0.6	-0.5	0.8	-1.6	-1.0	-0.8	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.2	0.4	0.3	0.7	0.6	0.1	-0.3	0.6	-0.6	-0.2	-0.7	-0.3	-1.1	-0.7	-0.0	-0.5	0.2	-0.3
Commuting to job workplace: Walk	0.2	0.2	1.3	0.7	0.4	0.3	-0.2	0.2	0.3	-0.9	0.5	0.1	0.1	0.3	0.4	-1.2	-0.3	0.4	0.2	0.4
Back pain experienced in last month	0.2	0.4	2.6	0.3	1.6	-0.4	1.1	0.1	0.0	-0.4	-0.1	-0.0	0.4	-0.1	-0.3	0.1	-1.2	-0.2	-0.4	0.0
Average weekly champagne plus white wine intake	0.2	0.3	1.6	0.0	0.0	-0.6	1.3	-0.0	0.7	0.6	0.4	0.5	0.3	0.4	0.4	0.2	0.0	0.7	0.2	0.6
Myopia	0.2	0.3	1.1	0.4	-1.1	-0.3	-0.6	0.6	0.4	0.6	0.6	0.3	-0.3	0.3	0.6	0.1	0.6	0.4	1.0	0.4
Blood Red Count	0.1	1.3	4.0	-1.0	1.9	-1.9	0.1	-1.0	-0.7	-1.4	-1.4	-0.6	-0.6	-0.1	-0.0	-1.5	-2.0	-0.8	-1.1	-0.6
Fluid intelligence score	0.1	0.2	0.8	0.1	0.1	0.6	0.9	-0.1	-0.3	-0.9	-0.4	-0.5	0.8	-0.2	0.4	0.2	-0.4	-0.3	-0.5	-0.3
Number of live births	0.1	0.2	1.0	0.1	-0.4	-0.3	0.1	-0.3	-0.1	-0.4	-0.2	-0.0	1.0	0.5	-0.8	0.0	0.0	-0.0	-0.2	-0.2
Prospective memory result	0.1	0.1	1.2	-0.2	-0.3	0.4	-1.1	-0.1	0.1	0.2	0.2	0.2	-0.3	-0.0	0.3	0.4	-0.3	0.2	-0.0	0.1
Number of full sisters	0.1	0.1	0.8	0.1	0.3	-0.8	0.1	-0.0	-0.3	0.2	0.1	-0.3	-0.2	0.0	-0.2	-0.5	0.9	-0.2	0.0	-0.3
Ever taken oral contraceptive pill	0.1	0.1	0.4	-0.4	-0.7	0.3	-0.3	-0.3	-0.2	0.1	-0.2	-0.1	-0.6	0.0	-0.4	-0.3	-0.5	-0.1	-0.0	-0.2
Financial situation satisfaction	0.1	0.1	0.6	0.2	-0.2	0.5	0.3	0.2	-0.3	-0.2	0.2	-0.3	0.1	-0.4	-0.8	0.2	-0.6	-0.4	0.4	-0.4
Pain experienced in last month	0.1	0.2	1.1	0.3	0.1	0.5	-0.5	-0.1	-0.1	0.8	-0.4	-0.2	-0.3	-0.3	-0.8	1.1	-0.8	-0.3	0.1	-0.2
Heart disease (siblings)	0.1	0.2	0.7	0.3	-0.1	-0.3	-0.2	-0.3	-0.6	0.1	0.2	-0.6	0.1	-0.3	-0.8	-0.0	0.2	-0.5	-0.2	-0.6
Blood Eosinophil Count	0.0	0.3	1.7	0.0	1.1	-1.3	-0.7	-0.1	-0.3	0.6	-0.3	-0.3	-0.2	-0.4	-0.0	0.9	0.5	-0.3	-0.2	-0.3
Hair Pigment	0.0	1.1	8.3	0.8	-0.4	-0.3	-0.9	-0.9	0.5	-2.9	-0.4	0.5	1.4	0.5	-1.2	0.9	-1.1	0.5	-0.7	0.5

Hub : Genes

OAF

Models

Trait associations