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chr17:3,371,501-6,068,117

Best TWAS P=1.03e-09 · Best GWAS P=4.28e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RABEP1 0.13 0.03 lasso 13 0.02 7.2e-02 -4.3 -5.4 6.4e-08 -0.80 0.03 0.84 FALSE
2 GTEx Artery Coronary RP11-810M2.2 0.30 0.02 lasso 4 0.02 8.5e-02 4.9 5.4 6.8e-08 -0.03 0.02 0.70 TRUE
3 GTEx Brain Putamen basal ganglia AC012146.7 0.30 0.03 enet 23 0.03 7.6e-02 3.7 -5.3 9.9e-08 -0.45 0.08 0.25 FALSE
4 GTEx Esophagus Gastroesophageal Junction DHX33 0.12 0.08 lasso 5 0.07 1.8e-03 5.8 -5.6 2.2e-08 -0.96 0.02 0.96 FALSE
5 GTEx Esophagus Gastroesophageal Junction RABEP1 0.19 -0.01 lasso 13 0.00 4.2e-01 4.7 -5.4 6.7e-08 -0.82 0.03 0.81 FALSE
6 GTEx Esophagus Gastroesophageal Junction GP1BA 0.35 0.16 lasso 11 0.18 5.9e-07 3.5 5.3 9.3e-08 0.56 0.26 0.59 FALSE
7 GTEx Esophagus Muscularis RABEP1 0.13 0.09 lasso 10 0.10 2.1e-06 5.8 -5.5 4.4e-08 -0.94 0.02 0.98 FALSE
8 GTEx Heart Atrial Appendage RABEP1 0.13 0.10 enet 11 0.12 7.2e-06 4.9 -5.2 1.9e-07 -0.85 0.06 0.93 FALSE
9 ROSMAP Brain Pre-frontal Cortex RABEP1 0.20 0.22 bslmm 546 0.20 7.4e-25 4.7 -5.1 2.9e-07 -0.75 0.61 0.38 FALSE
10 ROSMAP Brain Pre-frontal Cortex RPAIN 0.06 0.06 lasso 3 0.06 3.1e-08 5.8 -6.1 1.0e-09 -0.98 0.00 1.00 TRUE
11 The Cancer Genome Atlas Glioblastoma Multiforme NUP88 0.12 0.07 enet 12 0.09 1.2e-03 4.7 -5.3 1.0e-07 -0.78 0.02 0.67 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme RABEP1 0.23 0.13 blup 79 0.15 3.4e-05 4.8 -5.8 7.9e-09 -0.77 0.06 0.84 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma RABEP1 0.04 0.03 enet 5 0.03 1.5e-03 -4.5 -5.5 3.0e-08 -0.67 0.09 0.82 FALSE