Best TWAS P=1.08e-12 · Best GWAS P=3.5e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | CD79B | 0.15 | 0.16 | enet | 9 | 0.17 | 3.5e-14 | -6.9 | 7.1 | 1.1e-12 | -0.98 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CD79B | 0.02 | 0.02 | lasso | 2 | 0.01 | 3.0e-03 | -7.0 | 6.7 | 1.7e-11 | -0.99 | 0.00 | 0.92 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | CD79B | 0.15 | 0.00 | lasso | 6 | 0.02 | 4.1e-02 | -6.9 | 6.7 | 1.9e-11 | -0.89 | 0.00 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SCN4A | 0.04 | 0.01 | blup | 39 | 0.03 | 1.4e-07 | -7.0 | -6.0 | 1.8e-09 | 0.74 | 0.00 | 1.00 | FALSE |
| 4 | NTR | Blood | MAP3K3 | 0.02 | 0.01 | lasso | 2 | 0.01 | 2.0e-04 | 5.7 | -5.5 | 2.9e-08 | 0.39 | 0.88 | 0.11 | FALSE |
| 3 | GTEx | Artery Tibial | MAP3K3 | 0.05 | 0.07 | lasso | 5 | 0.07 | 2.9e-06 | 5.7 | 5.5 | 3.8e-08 | -0.39 | 0.80 | 0.05 | FALSE |