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chr6:124,741,508-127,355,237

Best TWAS P=1.69e-15 · Best GWAS P=1.71e-15 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Testis	HEY2	0.31	0.17	lasso	5	0.19	7.4e-09	-7.96	-8.0	1.7e-15	1.00	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPW	0.04	0.06	blup	35	0.05	9.2e-07	5.86	-6.0	1.8e-09	0.07	0.02	0.98	TRUE
7	GTEx	Thyroid	HEY2	0.22	0.24	lasso	6	0.23	1.0e-17	-7.96	-7.9	2.0e-15	0.99	0.00	1.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HEY2	0.15	0.20	lasso	10	0.21	6.7e-25	-7.87	-7.8	6.0e-15	0.98	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	HEY2	0.03	0.04	lasso	3	0.02	3.8e-03	6.94	-7.2	8.3e-13	0.89	0.01	0.97	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	HEY2	0.10	0.12	enet	15	0.13	9.8e-17	7.48	-7.0	3.4e-12	0.97	0.01	0.99	FALSE
9	METSIM	Adipose	NCOA7	0.05	0.05	enet	5	0.05	1.9e-07	5.29	6.1	9.9e-10	-0.68	0.94	0.03	FALSE
5	GTEx	Pancreas	HEY2	0.28	0.11	lasso	3	0.10	3.5e-05	-5.20	-6.0	2.0e-09	0.89	0.08	0.92	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CENPW	0.04	0.05	lasso	5	0.05	2.6e-06	6.00	-5.9	2.8e-09	0.07	0.02	0.98	FALSE
4	GTEx	Esophagus Muscularis	HINT3	0.08	0.00	enet	14	0.00	2.9e-01	7.54	-5.9	3.3e-09	0.78	0.03	0.64	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CENPW	0.04	0.06	lasso	10	0.06	2.4e-07	5.71	-5.7	1.4e-08	0.08	0.02	0.98	FALSE
8	METSIM	Adipose	HEY2	0.02	0.04	lasso	1	0.02	1.6e-04	-5.39	-5.4	7.0e-08	0.82	0.02	0.97	FALSE
3	GTEx	Artery Coronary	TPD52L1	0.31	-0.01	enet	19	0.05	7.0e-03	-0.15	-5.3	1.2e-07	0.60	0.03	0.54	FALSE