[Hub]/) : Traits : Weight : ← →

chr6:124,741,508-127,355,237

Best TWAS P=1.69e-15 · Best GWAS P=1.71e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPW 0.04 0.06 lasso 10 0.06 2.4e-07 5.71 -5.7 1.4e-08 0.08 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex HEY2 0.15 0.20 lasso 10 0.21 6.7e-25 -7.87 -7.8 6.0e-15 0.98 0.01 0.99 FALSE
3 GTEx Artery Coronary TPD52L1 0.31 -0.01 enet 19 0.05 7.0e-03 -0.15 -5.3 1.2e-07 0.60 0.03 0.54 FALSE
4 GTEx Esophagus Muscularis HINT3 0.08 0.00 enet 14 0.00 2.9e-01 7.54 -5.9 3.3e-09 0.78 0.03 0.64 FALSE
5 GTEx Pancreas HEY2 0.28 0.11 lasso 3 0.10 3.5e-05 -5.20 -6.0 2.0e-09 0.89 0.08 0.92 FALSE
6 GTEx Testis HEY2 0.31 0.17 lasso 5 0.19 7.4e-09 -7.96 -8.0 1.7e-15 1.00 0.01 0.99 TRUE
7 GTEx Thyroid HEY2 0.22 0.24 lasso 6 0.23 1.0e-17 -7.96 -7.9 2.0e-15 0.99 0.00 1.00 FALSE
8 METSIM Adipose HEY2 0.02 0.04 lasso 1 0.02 1.6e-04 -5.39 -5.4 7.0e-08 0.82 0.02 0.97 FALSE
9 METSIM Adipose NCOA7 0.05 0.05 enet 5 0.05 1.9e-07 5.29 6.1 9.9e-10 -0.68 0.94 0.03 FALSE
10 ROSMAP Brain Pre-frontal Cortex HEY2 0.10 0.12 enet 15 0.13 9.8e-17 7.48 -7.0 3.4e-12 0.97 0.01 0.99 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPW 0.04 0.05 lasso 5 0.05 2.6e-06 6.00 -5.9 2.8e-09 0.07 0.02 0.98 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma CENPW 0.04 0.06 blup 35 0.05 9.2e-07 5.86 -6.0 1.8e-09 0.07 0.02 0.98 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma HEY2 0.03 0.04 lasso 3 0.02 3.8e-03 6.94 -7.2 8.3e-13 0.89 0.01 0.97 FALSE