Best TWAS P=8.71e-15 · Best GWAS P=2.99e-22 conditioned to 7.02e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | KCNH2 | 0.34 | 0.09 | lasso | 5 | 0.12 | 5.0e-04 | 4.15 | -5.6 | 2.5e-08 | 0.67 | 0.02 | 0.83 | FALSE |
| 2 | GTEx | Brain Cerebellum | KCNH2 | 0.35 | 0.20 | enet | 24 | 0.28 | 4.8e-09 | -9.05 | -7.8 | 8.7e-15 | 0.83 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Uterus | GIMAP4 | 0.32 | -0.01 | enet | 42 | 0.02 | 1.4e-01 | -0.74 | -6.6 | 3.5e-11 | 0.48 | 0.05 | 0.20 | TRUE |