TWAS hub - GIMAP4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1070	0.0330	1.6e-04	0.039	NA	0.081	NA	0.089	3.6e-04	NA	3.5e-07	NA	1.0e-07
2	GTEx	Brain Cerebellar Hemisphere	0.5050	0.1510	9.4e-03	-0.002	NA	-0.008	NA	0.004	3.6e-01	NA	5.7e-01	NA	2.5e-01
3	GTEx	Nerve Tibial	0.1456	0.0416	1.9e-05	0.118	NA	0.105	NA	0.113	1.0e-08	NA	7.0e-08	NA	2.3e-08
4	GTEx	Skin Sun Exposed Lower leg	0.0850	0.0360	8.9e-03	-0.003	NA	0.008	NA	0.005	7.6e-01	NA	6.9e-02	NA	1.2e-01
5	GTEx	Thyroid	0.0830	0.0340	2.1e-03	0.012	NA	0.011	NA	0.009	4.1e-02	NA	4.2e-02	NA	6.1e-02
6	GTEx	Uterus	0.3230	0.1040	2.2e-03	-0.015	NA	0.018	NA	-0.003	9.3e-01	NA	1.4e-01	NA	3.7e-01
7	GTEx	Whole Blood	0.0840	0.0290	1.4e-04	0.060	NA	0.062	NA	0.049	3.0e-06	NA	2.2e-06	NA	2.6e-05
8	NTR	Blood	0.0239	0.0124	9.1e-03	0.025	0.001	0.021	0.020	0.020	9.8e-09	1.7e-01	1.5e-07	4.4e-07	2.7e-07
9	YFS	Blood	0.3145	0.0443	0.0e+00	0.123	0.116	0.155	0.154	0.152	6.1e-38	4.9e-36	3.1e-48	4.9e-48	1.9e-47
10	TCGA	Breast Invasive Carcinoma	0.0571	0.0337	6.3e-06	0.017	0.025	0.019	NA	0.020	1.9e-04	5.8e-06	7.6e-05	NA	5.0e-05
11	TCGA	Kidney Renal Clear Cell Carcinoma	0.0520	0.0281	4.8e-05	0.024	0.028	0.023	NA	0.025	8.1e-04	3.8e-04	1.2e-03	NA	7.9e-04
12	TCGA	Lung Adenocarcinoma	0.0612	0.0533	4.4e-03	0.013	0.006	0.020	NA	0.032	9.4e-03	5.4e-02	1.9e-03	NA	1.0e-04
13	TCGA	Pheochromocytoma and Paraganglioma	0.1190	0.0630	2.0e-04	0.078	0.090	0.068	NA	0.085	5.3e-04	2.0e-04	1.1e-03	NA	3.0e-04
14	TCGA	Prostate Adenocarcinoma	0.1021	0.0502	3.4e-09	0.070	0.084	0.089	NA	0.085	9.1e-08	4.3e-09	1.4e-09	NA	3.5e-09
15	TCGA	Skin Cutaneous Melanoma	0.1720	0.1020	3.5e-03	0.040	0.033	0.038	NA	0.067	3.1e-02	4.7e-02	3.5e-02	NA	7.5e-03
16	TCGA	Thyroid Carcinoma	0.1240	0.0630	3.4e-08	0.100	0.096	0.088	NA	0.094	5.7e-10	1.3e-09	6.9e-09	NA	2.0e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Diabetes (father)	3.8	4.7	10.4	-2.7	0.7	-2.4	-1.2	-1.1	-3.1	2.4	1.8	3.2	1.4	-1.7	3.1	-2.0	-2.5	-1.8	-1.3
Qualifications: A levels/AS levels or equivalent	3.5	7.7	15.4	-3.9	1.0	-2.8	-3.5	-3.9	-3.7	1.7	-0.3	1.5	-1.1	-3.1	0.3	-3.3	-3.5	-3.1	-3.0
Ovarian Cancer	3.0	4.0	9.5	-2.3	-2.2	-1.4	-2.6	-1.1	-1.6	0.9	-0.3	-0.1	-2.3	-2.1	-1.8	-2.9	-1.7	-2.6	-3.1
Verbal and Numeric Reasoning (VNR)	2.7	6.4	17.8	-2.2	1.9	-3.4	-2.2	-4.2	-2.0	2.8	-0.2	-0.1	-1.8	-3.5	-0.0	-3.4	-3.1	-0.0	-3.4
Diastolic blood pressure, automated reading	2.5	7.9	29.6	-1.4	-4.5	-0.1	-1.3	-1.3	0.3	0.8	-0.1	-3.9	-5.4	-2.8	-4.5	-2.9	-1.0	-1.1	-4.0
Tinnitus: Yes, but not now, but have in the past	2.3	2.5	5.9	-1.6	-2.4	-0.4	-1.7	0.1	-0.4	0.8	1.3	0.8	-2.3	-2.0	-0.6	-1.9	-1.8	-2.4	-1.9
Systolic Blood Pressure	2.2	11.0	32.7	-2.0	-4.3	-0.8	-3.3	-4.4	1.3	1.7	-0.5	-3.3	-5.7	-3.4	-4.6	-3.7	-1.9	-1.1	-4.8
Systolic blood pressure, automated reading	2.2	6.5	27.2	-1.0	-2.3	0.2	-1.2	-1.7	0.4	0.1	-1.1	-4.2	-5.2	-2.5	-4.6	-2.5	-1.1	-0.5	-3.5
Age at first live birth	2.0	3.6	10.6	1.8	-0.9	2.1	0.5	1.7	-0.5	-1.8	-0.8	0.0	2.8	3.0	0.8	3.0	2.0	0.6	3.2
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	6.0	1.5	-2.2	2.5	0.1	0.8	0.3	-2.1	-0.6	-0.5	0.2	2.0	-1.3	1.8	1.9	0.3	1.4
HDL Cholesterol	1.9	3.3	12.6	-0.0	2.0	1.0	-0.4	-0.4	3.2	-1.7	0.1	-2.5	-3.6	-1.3	-2.9	-1.1	-0.3	-0.5	-1.7
Qualifications: CSEs or equivalent	1.9	2.4	7.5	1.8	-2.7	2.2	1.8	1.4	1.5	-1.7	-0.8	-1.8	-0.3	1.4	-1.3	1.5	1.4	-0.4	1.4
Illnesses of father: High blood pressure	1.8	2.2	6.4	-1.2	-1.2	-1.6	-2.4	-2.5	-0.6	2.1	-0.8	-1.3	-0.9	-1.4	-0.6	-1.5	-1.3	0.3	-1.7
Breast Cancer	1.7	4.0	9.9	-1.8	-1.4	-2.7	-1.6	-2.5	-2.9	3.2	1.7	2.0	1.1	-1.5	2.1	-1.9	-2.0	-0.8	-1.6
Hair/balding pattern: Pattern 3	1.7	2.6	5.9	-2.1	0.7	-2.0	-1.7	-2.4	-1.6	1.7	-0.0	-0.2	-1.1	-2.3	0.2	-2.1	-1.6	-0.9	-2.0
Ever highly irritable/argumentative for 2 days	1.7	2.1	6.2	0.6	0.5	0.9	0.0	1.8	-0.4	-0.9	0.6	1.7	2.5	2.2	1.6	1.9	1.1	0.6	2.4
Medication: Amlodipine	1.7	2.4	6.3	-1.2	-0.8	-0.9	-2.5	-2.0	-1.8	0.6	-0.8	-0.9	-1.9	-1.6	-1.5	-1.8	-1.8	-0.9	-2.0
Had major operations	1.7	2.0	6.9	-2.0	0.3	-1.6	-1.8	-0.7	-1.5	0.7	-0.6	2.1	2.6	0.0	1.9	-0.6	-0.9	-1.4	-0.0
Alcohol drinker status: Never	1.7	2.0	5.9	-1.0	-0.0	-0.3	0.3	-2.0	-1.3	0.3	-1.3	-2.0	-2.4	-1.7	-2.1	-1.5	-0.7	-0.7	-1.8
Intelligence (Savage-Jansen 2018)	1.6	4.9	10.7	-2.4	0.9	-3.1	-2.3	-3.3	-1.1	2.3	-0.2	0.0	-1.4	-3.1	0.2	-3.2	-2.9	-0.6	-3.1
Major Depression (MDD)	1.6	1.9	11.0	-0.3	-0.4	-0.1	0.7	1.5	-0.5	0.3	1.4	3.3	2.3	0.9	2.2	0.5	0.1	-1.3	1.1
Allergy or Eczema	1.6	4.2	21.4	0.7	0.6	-0.6	-0.9	0.4	-1.9	0.5	-0.3	2.8	4.6	2.5	3.3	2.1	0.2	1.8	2.7
Ever had hysterectomy (womb removed)	1.6	1.8	4.1	1.2	-0.4	1.0	1.4	1.1	1.6	-0.5	1.1	1.1	1.3	1.9	0.5	1.6	2.0	1.8	1.6
Bilateral oophorectomy (both ovaries removed)	1.6	1.9	6.1	1.5	-0.1	1.3	1.2	2.5	0.1	-1.0	-0.3	0.7	1.9	2.0	0.2	1.7	1.7	0.2	1.8
Hair/balding pattern: Pattern 2	1.6	2.1	4.9	1.6	-1.1	2.2	1.0	1.6	1.4	-2.2	-0.5	-1.2	-0.4	1.7	-1.7	1.5	1.6	0.5	1.2
Fluid intelligence score	1.6	3.4	12.5	-1.2	1.5	-1.8	-1.4	-3.5	-1.1	1.0	-1.0	-1.1	-2.2	-2.4	-1.4	-2.4	-1.8	0.1	-2.7
Qualifications: College or University degree	1.6	4.9	11.7	-2.5	2.0	-2.9	-2.4	-3.4	-2.5	2.4	-0.3	0.4	-0.7	-2.7	0.7	-2.7	-2.7	-0.5	-2.5
Alcohol intake frequency.	1.6	3.7	9.1	2.8	-1.3	2.5	3.0	-1.2	1.1	-1.3	-1.0	-2.3	-1.8	1.0	-2.2	1.8	1.8	2.3	1.3
Illnesses of father: None of the above (group 1)	1.6	1.9	5.1	1.7	-0.2	1.6	0.6	1.1	-0.1	-1.8	-0.6	0.0	1.3	2.3	-0.3	2.0	2.1	1.1	2.0
Cholesterol lowering medication	1.6	2.4	8.3	2.6	-0.0	1.1	1.6	0.2	2.4	-0.2	1.4	0.2	0.3	1.6	0.3	1.6	2.2	2.9	1.2
Lupus	1.5	2.2	7.8	-1.5	-0.3	-1.6	-0.5	0.1	-1.8	1.4	1.1	2.8	1.8	-0.6	2.7	-0.7	-1.9	-1.0	-0.0
Blood Eosinophil Count	1.5	11.4	34.7	3.2	-0.4	0.9	2.9	3.2	0.4	0.9	-0.1	0.9	5.9	4.3	3.8	4.7	3.3	4.7	5.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	5.5	0.8	-1.6	1.1	0.2	1.9	1.1	-0.9	-0.6	0.6	2.4	2.3	0.3	1.8	1.4	-0.2	1.9
Noisy workplace	1.5	1.9	5.6	-1.7	-2.1	-2.2	-0.6	-0.3	0.1	2.4	0.5	0.9	0.4	-1.4	1.7	-1.4	-1.7	-0.2	-1.1
Eye problems/disorders: Cataract	1.5	1.7	6.1	-1.3	0.1	-1.4	-0.9	1.1	-2.2	1.5	-0.1	1.6	2.5	0.2	2.1	-0.2	-0.7	-0.7	0.3
Pain type(s) experienced in last month: Hip pain	1.5	1.8	4.2	-1.5	-2.0	-0.8	-1.4	-1.7	-1.6	0.6	-1.2	-0.4	-0.9	-1.2	-1.3	-1.4	-1.2	-1.7	-1.6
Alcohol drinker status: Previous	1.5	1.7	3.1	1.6	-0.1	1.5	1.8	1.4	1.2	-1.6	-1.0	-0.9	0.6	1.5	-0.4	1.7	1.5	1.4	1.6
Medication: Co-codamol	1.4	1.6	2.9	1.5	-0.9	1.4	1.5	1.2	0.5	-1.0	1.7	1.5	0.8	1.4	0.8	1.5	1.7	0.6	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	4.1	-1.2	0.2	-1.5	-0.8	-1.3	-1.2	1.6	-0.1	0.1	-1.4	-2.0	-0.1	-1.8	-1.7	-0.5	-1.8
Alzheimer’s Disease (in mother)	1.3	1.5	5.4	-2.3	-0.2	-1.3	-0.4	-0.4	-1.2	1.3	-0.4	-0.0	-0.9	-1.8	0.2	-1.7	-1.7	-0.9	-1.5
Triglycerides	1.3	2.1	8.6	-1.9	-1.0	-0.9	-1.5	-0.3	-2.9	1.0	-0.4	1.7	1.7	-0.1	1.3	-0.6	-1.4	-2.3	-0.1
Impedance of leg (left)	1.3	6.4	36.1	-1.4	-0.1	-3.0	-0.1	3.5	6.0	2.4	-0.4	1.3	4.4	0.3	3.9	-0.2	-1.1	0.2	0.8
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	6.2	-1.1	1.8	-1.9	-1.0	-1.7	-1.5	1.2	1.1	1.4	0.3	-1.5	1.7	-1.3	-2.5	-0.8	-0.9
Eye problems/disorders: None of the above	1.3	1.5	5.8	0.1	-0.4	-0.2	-0.2	-2.4	1.8	0.2	1.3	-0.6	-2.4	-1.5	-0.9	-1.2	-0.6	0.1	-1.4
Friendships satisfaction	1.3	1.6	7.5	0.2	1.6	-0.6	-0.7	-0.5	0.4	1.2	2.7	2.7	0.6	0.0	2.1	0.2	0.2	1.3	0.5
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	8.1	0.3	-2.4	1.8	1.0	0.3	-0.8	-1.8	-0.3	-1.1	-2.3	-0.0	-2.9	-0.2	0.8	-1.5	-0.8
Hayfever, allergic rhinitis or eczema	1.2	2.6	12.6	0.2	-0.3	-0.7	-1.3	0.1	-2.0	0.4	0.2	2.8	3.5	1.7	2.8	1.2	-0.1	0.8	1.7
Supplements: Glucosamine	1.2	1.6	5.7	0.5	1.1	1.6	0.6	1.0	1.0	-2.4	-0.9	-0.1	1.3	1.7	-0.4	1.4	1.5	-1.3	1.4
Medication: Allopurinol	1.2	1.6	5.6	-0.5	0.5	-0.8	0.1	1.8	0.9	1.1	2.4	2.2	1.6	0.2	2.4	0.2	-0.1	0.7	0.6
Tinnitus: Yes, now most or all of the time	1.2	1.4	8.4	0.2	0.7	0.1	0.5	0.8	0.1	0.2	-1.3	0.6	2.9	1.6	1.4	1.5	0.2	-0.1	1.9
Hand grip strength (left)	1.1	3.0	11.9	0.3	0.4	-1.3	2.0	-0.8	-3.1	2.3	1.9	1.8	2.0	-0.1	3.5	0.4	-0.3	1.6	0.9
Diabetes (mother)	1.1	1.4	4.3	1.4	2.1	0.3	2.0	-1.0	0.6	0.6	1.5	0.9	0.2	0.1	1.3	0.9	0.2	1.8	0.9
Impedance of leg (right)	1.1	5.5	35.9	-1.2	-0.0	-3.0	0.5	2.9	6.0	2.4	-0.4	0.6	3.5	-0.2	3.5	-0.5	-1.2	0.6	0.4
Hand grip strength (right)	1.1	2.9	11.1	0.1	0.8	-1.5	1.4	-0.4	-3.0	2.6	2.1	1.9	1.6	-0.5	3.3	-0.1	-0.7	1.6	0.5
High blood pressure	1.1	3.1	14.9	0.6	-3.9	0.7	-0.9	-2.1	0.4	0.5	-0.0	-2.6	-3.1	-0.6	-2.8	-0.8	0.4	0.9	-1.5
Number of incorrect matches in round	1.1	1.8	7.5	-0.0	2.1	-0.1	-0.6	1.8	1.3	-0.7	-1.2	0.4	2.7	1.5	1.5	1.3	0.1	0.3	1.7
Qualifications: None of the above	1.1	2.4	11.0	1.2	-2.0	1.8	1.9	1.7	3.3	-1.0	0.0	-0.6	-0.6	1.2	-0.9	1.2	2.2	0.8	1.1
Medication: Ramipril	1.1	1.4	5.2	-1.0	0.3	-2.0	-1.4	-1.7	-0.7	2.3	0.1	0.3	0.3	-1.0	0.5	-1.2	-1.3	0.6	-1.3
Alcohol intake versus 10 years previously	1.1	1.7	5.8	2.0	-0.3	1.0	2.4	-0.1	1.9	-0.6	-0.0	-0.1	0.9	1.2	0.4	1.8	1.1	1.5	1.8
Length of working week for main job	1.1	1.2	6.2	-0.6	-1.5	-0.2	-0.2	-0.1	-2.5	0.7	1.6	1.8	0.6	-0.1	1.6	0.1	-0.2	-1.0	0.5
Comparative body size at age 10	1.1	3.1	15.8	-0.9	-1.1	-0.9	-1.4	-0.3	-4.0	2.3	1.9	2.9	2.1	0.3	2.6	-0.1	-0.4	0.4	0.3
Hypertension (Self-reported)	1.1	3.0	13.6	0.8	-3.7	0.8	-0.5	-2.0	0.8	0.5	0.3	-2.6	-3.2	-0.6	-2.5	-0.7	0.6	1.2	-1.3
Bipolar Disorder (2018)	1.0	1.5	3.5	-0.9	0.4	-1.9	-1.8	-1.2	-0.5	1.9	0.9	1.0	-0.2	-1.3	0.9	-1.4	-1.8	0.6	-1.4
Crohns Disease (2017)	1.0	2.1	6.2	-0.4	-2.1	0.4	-1.2	0.8	-2.5	-0.6	-2.3	0.6	2.3	1.3	-0.0	0.8	-0.9	-2.3	1.1
Reaction Time	1.0	1.9	6.8	-0.8	-0.6	-1.5	0.1	-0.4	2.5	2.5	1.3	1.2	1.2	-0.6	2.6	-0.4	-0.9	1.1	0.0
Prostate Cancer	1.0	1.3	5.6	-0.4	0.5	-0.4	-1.1	0.2	-1.3	0.1	0.7	2.3	2.4	0.8	2.1	0.4	-0.1	-0.9	0.9
Townsend deprivation index at recruitment	1.0	1.4	6.2	0.6	-1.5	1.6	1.3	2.5	2.0	-1.1	0.0	-0.1	-0.2	1.0	-0.4	1.0	1.0	-0.5	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	5.3	-1.6	0.8	-2.2	-1.0	-0.2	2.0	2.3	0.3	0.6	-0.6	-2.0	0.5	-2.1	-1.9	-0.8	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	5.8	-1.8	0.9	-2.4	-1.6	-0.1	1.8	2.1	0.4	0.6	-0.2	-1.9	0.7	-2.1	-1.8	-1.0	-2.0
Pain all over the body in last month	1.0	1.0	6.7	0.1	-0.6	0.2	-0.1	0.3	1.1	-0.2	1.4	0.7	-2.6	-1.0	-1.4	-1.1	0.2	0.1	-1.4
Trunk fat-free mass	1.0	5.5	69.4	0.3	1.1	0.5	0.6	-3.1	-8.3	0.5	1.4	1.2	-1.5	-0.8	0.1	-0.1	-0.2	-0.2	-0.1
Happiness	1.0	1.2	3.6	-1.1	-0.2	-1.2	-1.5	-1.9	0.0	1.5	1.4	1.7	0.1	-0.8	1.3	-0.8	-0.6	0.3	-0.5
Trunk predicted mass	1.0	5.4	68.6	0.3	1.1	0.5	0.6	-3.1	-8.3	0.4	1.4	1.2	-1.5	-0.8	0.0	-0.1	-0.2	-0.2	-0.2
Gout (self-reported)	1.0	1.4	3.0	1.3	-0.2	0.9	0.8	1.7	1.6	-0.8	0.8	0.5	1.0	1.4	0.5	1.6	1.5	1.4	1.6
Number of children fathered	1.0	1.2	5.4	-0.2	-1.2	-0.8	0.9	2.3	-0.8	1.5	0.4	0.9	1.4	-0.1	1.9	0.2	-0.3	0.6	0.5
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.1	0.6	-1.7	1.1	0.9	1.7	-0.2	-0.3	-0.4	0.3	1.4	1.5	0.6	1.5	0.7	0.1	1.7
Neck or shoulder pain in last month	1.0	1.4	4.6	1.2	-1.4	2.1	1.4	1.8	0.1	-1.4	-0.0	0.2	-0.2	1.1	-0.7	1.5	0.8	-0.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	6.4	-1.7	1.7	-1.7	-0.2	-1.3	-2.5	1.6	1.1	1.8	0.4	-1.4	1.9	-1.0	-1.4	-0.9	-0.6
Commuting to job workplace: Walk	1.0	1.0	4.5	0.9	-0.4	0.9	1.4	1.1	2.1	-0.6	-1.0	-1.1	-1.2	0.1	-1.3	0.3	0.9	0.9	-0.1
Osteoarthritis (self-reported)	1.0	1.3	6.4	1.0	-1.0	1.3	1.1	2.5	-0.3	-1.2	-0.5	-0.4	0.6	1.3	-0.4	1.3	1.3	0.2	1.3
Medication: Aspirin	1.0	1.3	5.5	-1.3	-0.3	-1.7	-0.8	-0.5	-0.3	2.4	0.6	0.7	-0.3	-1.5	0.3	-1.6	-1.2	-0.6	-1.6
Vascular/heart problems diagnosed by doctor	1.0	2.8	12.3	-0.1	3.5	-0.3	1.2	2.0	-0.5	-1.0	-0.2	1.9	3.1	1.0	2.5	1.3	0.0	-0.4	1.9
Impedance of whole body	1.0	5.0	39.4	-0.9	0.2	-2.0	-0.3	3.4	6.3	1.1	-0.3	1.0	3.6	0.6	2.8	0.1	-0.9	0.1	0.8
Blood Red Count	0.9	8.9	63.8	-2.8	2.2	-3.3	-0.4	-1.9	-8.0	3.2	1.1	2.5	1.5	-2.1	2.3	-2.3	-3.4	-1.5	-1.8
Waist Hip Ratio (WHR)	0.9	4.0	16.2	0.9	1.2	-1.6	1.3	-0.2	-2.2	2.5	2.0	2.4	2.9	0.5	4.0	0.8	0.1	2.9	1.5
Cardiovascular Disease	0.9	2.9	10.6	0.3	-3.2	0.2	-2.2	-2.8	0.7	1.3	1.1	-1.4	-2.7	-0.7	-1.9	-1.1	0.4	0.9	-1.7
Type 2 Diabetes (T2D) (2018)	0.9	1.7	5.1	-0.7	1.7	-1.8	-2.1	-0.7	-2.3	1.6	-1.2	0.5	1.4	-0.3	0.9	-0.7	-1.3	0.1	-0.6
Chronotype (morning person)	0.9	2.2	12.7	-0.9	-0.1	-1.6	0.2	-2.3	-3.6	2.1	0.6	0.1	-0.4	-1.6	0.8	-1.4	-1.1	-0.0	-1.3
Number of treatments/medications taken	0.9	1.6	7.5	-1.4	-2.7	-0.5	-1.4	0.4	-1.7	1.2	-0.5	0.1	-0.6	-0.7	-0.8	-1.1	-0.8	-2.0	-1.2
Leg fat-free mass (left)	0.9	4.7	58.1	1.1	-0.1	1.6	0.7	-2.4	-7.6	-0.8	1.0	0.6	-1.7	0.2	-1.0	0.7	0.6	0.1	0.4
Leg predicted mass (left)	0.9	4.7	58.1	1.0	-0.1	1.6	0.7	-2.4	-7.6	-0.7	1.0	0.5	-1.8	0.1	-1.1	0.6	0.5	0.0	0.3
Alcohol usually taken with meals	0.9	1.4	4.8	1.1	0.2	0.2	0.7	1.2	0.9	-0.8	-2.2	-2.1	0.8	1.1	-0.5	1.0	1.2	1.7	0.8
Diabetes (self-reported)	0.9	1.5	6.4	-0.7	2.5	-1.0	-1.1	-0.4	-2.3	1.0	-0.5	1.2	1.6	0.0	1.2	-0.2	-1.3	-0.7	0.1
Time employed in main current job	0.9	1.0	3.9	-0.1	-1.0	1.2	0.7	1.1	-0.9	-0.9	-2.0	-1.4	-0.4	0.6	-1.8	0.7	0.6	-0.3	0.5
Illnesses of mother	0.9	1.1	3.6	-1.3	1.2	-1.5	-1.2	1.0	-1.3	0.5	-0.7	0.4	1.9	-0.1	1.2	-0.4	-1.2	-1.2	-0.0
Loud music exposure frequency	0.9	1.0	4.0	0.8	0.1	-0.1	0.6	-1.3	1.6	0.9	1.8	0.7	0.3	0.4	1.1	0.6	0.6	2.0	0.7
Arm fat-free mass (right)	0.9	4.6	60.5	0.8	0.6	0.9	1.2	-2.3	-7.8	0.1	1.3	1.2	-0.5	0.1	0.4	0.7	0.3	0.3	0.7
Migraine (self-reported)	0.9	1.2	3.6	-1.6	-0.1	-0.9	-1.5	-0.5	-0.8	0.6	0.0	0.3	-0.5	-1.4	0.4	-1.2	-1.9	-1.9	-0.9
Arm predicted mass (right)	0.9	4.7	62.1	0.7	0.8	0.8	1.4	-2.2	-7.9	0.2	1.2	1.1	-0.5	-0.0	0.4	0.6	0.2	0.2	0.7
Number of full sisters	0.9	1.1	3.9	1.1	0.3	1.5	2.0	0.5	0.6	-1.2	0.1	-0.5	-0.9	0.7	-1.2	0.9	1.8	0.8	0.5
Leg pain on walking	0.9	1.2	4.4	1.1	-2.1	1.1	0.7	1.2	-0.6	-0.1	0.9	1.4	0.7	1.2	0.5	1.2	1.0	-0.1	1.4
Whole body fat-free mass	0.9	5.3	67.6	0.8	0.7	1.1	0.8	-2.8	-8.2	-0.2	1.3	1.0	-1.6	-0.2	-0.5	0.4	0.3	0.0	0.2
Leg fat-free mass (right)	0.9	4.8	59.3	1.1	0.2	1.8	0.4	-2.3	-7.7	-0.9	1.0	0.9	-1.4	0.4	-1.0	0.8	0.6	-0.2	0.5
Long-standing illness, disability or infirmity	0.9	1.4	2.7	1.6	-0.9	1.6	-0.2	1.6	-0.5	-1.3	-0.7	-0.3	0.5	1.6	-0.8	1.6	1.5	-0.2	1.5
Whole body water mass	0.9	5.3	69.2	0.8	0.7	1.1	0.8	-2.8	-8.3	-0.0	1.3	1.1	-1.4	-0.2	-0.3	0.4	0.2	0.0	0.3
Leg predicted mass (right)	0.9	4.7	59.0	1.1	0.2	1.8	0.4	-2.2	-7.7	-0.9	1.0	0.9	-1.4	0.4	-0.9	0.8	0.7	-0.1	0.6
Eye problems/disorders: Glaucoma	0.9	1.0	2.8	0.9	-1.3	1.0	0.9	1.7	0.2	-0.9	-1.2	-0.9	0.1	1.0	-0.8	1.0	1.2	1.0	0.8
Medication: Bendroflumethiazide	0.9	1.3	5.4	0.3	-2.3	-0.0	-1.6	-0.7	0.3	0.3	-1.0	-1.9	-1.5	-0.3	-1.9	-0.4	0.3	1.0	-0.8
Basal metabolic rate	0.9	4.8	64.6	0.9	0.1	1.1	0.9	-2.2	-8.0	-0.1	1.3	1.1	-1.2	-0.0	-0.2	0.6	0.4	0.1	0.5
Arm fat-free mass (left)	0.9	4.5	62.1	0.8	0.5	0.8	0.9	-2.0	-7.9	0.2	1.1	1.0	-0.7	-0.0	0.2	0.5	0.3	0.3	0.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	6.1	0.4	-0.9	0.2	0.8	1.4	-2.5	0.1	-0.6	0.3	1.8	1.2	0.7	1.1	0.4	0.7	1.1
Heart disease (siblings)	0.9	1.1	6.6	-1.4	-2.6	-0.5	-0.8	0.5	-1.3	0.7	-0.8	-0.2	-0.4	-0.8	-0.4	-1.1	-1.3	-1.1	-1.0
Arm predicted mass (left)	0.9	4.7	64.2	0.8	0.3	0.7	1.2	-1.7	-8.0	0.3	1.4	1.3	-0.5	0.1	0.5	0.6	0.3	0.3	0.6
Age at First Birth	0.8	1.2	2.4	1.2	-0.4	1.5	0.3	1.2	1.5	-1.4	0.1	-0.4	0.5	1.5	-0.4	1.4	1.5	0.5	1.2
Ulcerative Colitis	0.8	1.2	5.6	-1.4	1.4	-0.8	-2.4	-0.8	-0.5	0.0	-0.8	-0.2	-0.6	-0.9	-0.5	-1.3	-1.0	-1.2	-1.3
Vitamin and mineral supplements	0.8	1.1	3.3	-0.4	-1.8	-0.9	-0.0	0.5	-0.4	1.5	0.5	-0.2	-1.7	-1.6	-0.4	-1.3	-1.0	-0.2	-1.3
Father’s age at death	0.8	1.1	3.1	1.1	1.8	1.2	1.2	-1.0	0.1	-1.5	-0.6	-1.1	-1.5	0.0	-0.8	0.8	0.5	0.4	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	4.3	-1.4	-1.4	-1.0	-0.5	-1.2	-1.2	1.4	0.1	0.5	-0.3	-1.1	0.5	-1.2	-2.1	-1.1	-0.9
Falls in the last year	0.8	1.1	3.6	1.1	-1.9	1.3	0.9	1.6	-0.6	-1.0	-0.8	-0.2	0.5	1.2	-0.7	1.2	0.7	0.0	1.1
Depression (self-reported)	0.8	0.9	4.2	0.8	0.1	0.1	1.0	0.7	2.1	0.5	1.1	1.2	0.7	0.6	0.9	0.6	0.8	1.5	0.8
Birth weight of first child	0.8	1.5	9.2	0.9	-0.5	0.2	-0.7	0.5	-3.0	0.1	-0.4	1.2	1.9	1.3	1.3	1.2	0.1	1.1	1.4
Headache pain in last month	0.8	1.3	4.5	0.2	-0.9	0.8	-1.1	-0.3	1.9	-0.8	-1.5	-1.8	-1.8	-0.3	-2.1	-0.3	0.1	-0.4	-0.6
Comparative height size at age 10	0.8	4.3	35.9	-1.7	1.1	-1.5	-1.3	-1.2	-6.0	1.9	1.0	2.2	0.2	-1.3	1.2	-1.3	-2.4	-1.5	-0.8
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.0	1.1	-0.7	1.7	0.8	0.5	-0.4	-1.6	-0.1	-0.9	-0.7	0.9	-1.1	0.9	1.1	-0.3	0.6
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.4	0.6	1.0	0.9	0.2	1.1	0.7	-1.2	-1.6	-1.4	0.6	0.9	-0.5	1.2	1.0	0.2	1.2
Knee pain experienced in last month	0.8	1.2	4.5	1.3	-0.6	0.8	2.1	-0.1	-0.2	0.3	1.3	1.0	1.0	0.6	1.5	1.4	0.3	0.9	1.8
Diabetes diagnosed by doctor	0.8	1.3	5.1	-0.4	2.3	-0.9	-0.6	-0.4	-2.1	1.3	-0.2	1.6	1.6	0.2	1.3	0.1	-0.7	0.1	0.3
Qualifications: nursing, teaching	0.8	1.2	6.7	0.1	2.4	0.5	-0.8	-2.6	-1.7	-1.0	1.2	1.0	0.0	0.3	0.2	0.1	0.0	-0.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.2	0.8	-0.2	0.6	0.6	0.9	-1.6	-0.1	-0.3	0.0	1.5	1.1	1.0	1.5	0.1	0.4	1.8
Medication: Gliclazide	0.8	0.9	2.5	1.4	-0.4	0.5	0.8	0.7	0.9	0.0	0.3	0.4	0.9	1.1	0.7	1.3	0.9	1.6	1.4
Medication: Blood pressure	0.8	1.6	9.9	0.5	-3.1	0.1	-1.3	-1.2	1.0	1.1	0.1	-1.6	-1.6	-0.3	-1.3	-0.6	0.3	1.4	-1.1
Number of operations (self-reported)	0.8	1.1	4.6	0.5	0.2	0.2	-0.7	0.3	-2.1	-0.7	0.0	1.7	2.0	1.5	0.6	0.7	0.8	-0.6	0.8
Irritability	0.8	1.3	3.1	1.5	0.7	1.3	1.4	1.1	0.4	-0.8	-0.5	-0.1	1.2	1.6	0.2	1.7	0.8	0.9	1.8
Age started oral contraceptive pill	0.8	1.0	3.6	0.0	1.9	-0.6	0.7	-0.5	-1.1	0.6	1.3	1.4	1.3	0.2	1.7	0.2	-0.2	0.9	0.5
Ever depressed for a whole week	0.8	0.9	5.5	-0.5	0.9	-0.1	-0.2	-0.4	-0.4	0.3	1.1	2.3	1.4	0.5	1.5	0.3	-0.1	-1.3	0.7
Alzheimer’s Disease (including proxy)	0.7	1.0	4.2	-2.1	-0.1	-1.1	-0.8	0.2	-1.1	1.1	0.2	1.0	-0.2	-1.2	0.7	-1.2	-1.1	-1.3	-1.0
Irritable Bowel Disease (IBD)	0.7	1.7	6.6	-1.3	-0.4	-0.3	-2.1	0.2	-2.1	-0.1	-1.4	1.4	1.8	0.4	0.5	-0.0	-1.4	-2.6	0.4
Ulcerative Colitis (UC)	0.7	1.4	5.7	-1.7	0.6	-1.1	-2.4	-0.6	-1.2	0.4	-0.5	1.3	0.4	-0.8	0.4	-1.1	-1.5	-1.8	-0.8
Bipolar Disorder (2011)	0.7	0.6	5.3	-0.7	0.0	-0.7	-2.3	-0.6	-1.1	0.3	-0.3	0.1	-0.3	-0.4	0.0	-0.7	-1.1	-0.3	-0.6
HbA1C	0.7	0.8	1.9	-0.5	-0.7	-0.7	-1.0	-0.4	1.0	1.4	0.7	0.2	-1.2	-1.1	-0.1	-1.2	-1.1	-0.1	-1.2
Height	0.7	13.9	73.3	-2.4	8.0	-3.4	-0.6	-3.1	-8.6	2.6	1.9	3.6	1.6	-2.2	3.8	-1.6	-3.2	-0.8	-0.8
Medication: Metformin	0.7	1.0	3.5	-0.4	1.9	-1.1	-0.6	-1.0	-1.2	1.3	-0.4	-0.5	-0.7	-1.1	-0.2	-0.9	-1.3	0.6	-1.0
Multivitamins +/- minerals	0.7	0.8	2.2	0.8	1.1	0.8	-0.8	-0.4	0.6	-1.5	-0.9	-0.4	1.1	1.4	-0.5	1.1	0.9	0.1	0.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.2	-0.3	0.3	-0.9	0.1	-0.6	-0.2	1.4	1.5	0.5	-0.4	-1.2	1.4	-0.7	-1.5	0.4	-0.4
Sitting height	0.7	4.7	22.9	0.1	3.9	-0.2	0.5	-1.6	-4.8	0.9	2.8	3.5	1.3	-0.1	2.8	0.6	-1.0	-0.6	1.1
High blood pressure (mother)	0.7	1.0	4.6	1.0	-2.1	1.0	0.5	-1.4	0.6	-0.1	1.2	-0.4	-1.9	-0.3	-0.8	-0.1	0.3	0.7	-0.3
Waist circumference	0.7	2.5	31.5	0.5	-1.4	0.5	1.3	-0.1	-5.6	0.3	1.5	1.1	-0.4	-0.0	0.4	0.3	0.1	0.1	0.4
Had other major operations	0.7	0.8	2.7	1.2	1.6	0.6	0.5	-0.3	-1.0	-0.6	0.4	0.4	0.9	1.2	0.2	1.0	1.2	1.1	0.9
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.7	0.6	0.8	-0.4	1.4	1.6	-0.3	0.9	0.4	0.6	1.4	0.5	1.5	0.7	0.2	1.4	0.8
Weight	0.7	3.3	43.8	0.8	-1.5	1.1	1.0	-0.6	-6.6	-0.2	1.2	1.0	-0.8	0.2	-0.1	0.7	0.3	-0.0	0.6
Glaucoma (self-reported)	0.7	0.8	2.2	1.0	0.4	1.0	1.5	0.4	-0.0	-1.0	-1.0	-1.0	-0.4	0.6	-0.8	0.9	0.9	1.0	0.8
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.2	0.1	0.2	1.3	-0.7	0.5	-1.4	-1.5	-0.6	0.5	1.0	1.3	-0.3	1.1	0.6	-0.9	1.2
Worry too long after embarrassment	0.7	1.1	7.3	0.5	2.7	0.6	0.6	0.2	-0.9	-0.5	0.8	1.3	1.3	1.0	1.0	1.0	0.3	0.2	1.2
Wheeze or whistling in the chest in last year	0.7	1.2	4.1	0.7	-2.0	1.1	-0.5	0.0	-1.1	-0.4	1.6	1.6	0.8	1.3	0.9	1.0	0.8	-0.1	1.2
Health satisfaction	0.7	1.0	4.1	-0.3	-0.3	-0.8	-0.3	0.8	-0.8	1.5	1.7	2.0	0.6	-0.2	1.7	-0.1	-0.2	0.7	0.4
Suffer from ‘nerves’	0.7	1.1	3.1	1.0	-0.7	1.8	1.6	1.1	1.0	-0.9	-0.5	-0.7	0.2	1.1	-0.7	1.4	0.7	-0.1	1.4
Family relationship satisfaction	0.7	0.8	2.5	-1.0	0.8	-1.0	-1.6	-1.3	1.0	1.1	0.7	0.6	-0.6	-0.9	0.6	-0.8	-0.9	0.6	-0.7
Illnesses of father: Heart disease	0.7	1.0	2.8	-0.5	0.3	-1.4	-1.3	-1.4	0.1	1.7	1.0	0.7	-0.1	-1.1	0.9	-1.0	-1.4	0.2	-1.0
Smoking status: Current	0.7	1.1	5.4	1.0	-2.3	0.1	1.0	0.3	1.9	1.2	1.4	0.5	-0.0	0.3	0.5	0.3	1.1	0.9	0.2
Hearing aid user	0.7	0.8	2.0	0.3	-0.7	1.3	1.2	1.1	0.9	-1.4	-0.4	-0.3	-0.4	0.7	-1.0	0.7	1.0	-1.1	0.7
Coronary Artery Disease (CAD)	0.6	0.7	2.8	-0.7	-1.7	-0.1	-1.3	-0.0	-0.1	0.5	-0.3	-0.2	-1.1	-0.5	-1.4	-0.7	-0.4	-0.7	-0.9
Crohns Disease (2012)	0.6	0.9	3.2	-0.3	-1.5	0.5	-1.8	0.5	-0.9	-0.8	-1.4	0.3	1.0	0.9	-0.5	0.3	-0.5	-1.6	0.4
LDL Cholesterol	0.6	0.9	3.8	0.5	-0.5	0.6	-1.2	1.9	-0.3	-0.9	-1.2	-0.1	1.0	1.4	-0.1	1.1	1.1	0.2	1.1
Rheumatoid Arthritis	0.6	0.8	3.9	-0.6	-1.1	-0.3	-0.6	0.7	-0.1	-0.5	-2.0	-1.5	0.0	-0.4	-0.1	-0.6	-1.0	-1.4	-0.3
Blood Platelet Count	0.6	7.4	16.6	-3.5	0.7	-4.0	-1.8	-0.8	-3.2	3.1	-2.0	-0.5	-1.0	-3.8	0.0	-3.6	-4.1	-2.0	-3.6
Heel T-Score	0.6	4.5	12.1	-3.5	0.2	-3.1	-2.0	0.4	2.4	2.9	-0.5	0.8	0.9	-2.2	1.7	-2.3	-2.6	-2.6	-1.8
Smoking Status	0.6	1.4	6.4	0.9	-2.5	0.2	0.9	0.7	-0.1	1.5	2.0	1.8	-0.6	0.0	0.7	0.0	1.3	1.1	0.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	4.9	0.3	-1.0	0.1	-0.6	0.1	-2.2	0.1	0.1	1.1	1.2	0.7	1.0	0.7	-0.3	0.0	1.0
Stomach or abdominal pain in last month	0.6	0.7	5.0	0.0	-2.2	0.6	1.0	0.2	-1.6	0.1	-0.8	-0.8	-0.4	-0.1	-0.2	0.3	-0.9	-0.5	0.2
Body mass index (BMI)	0.6	2.4	15.7	1.1	-3.1	1.7	1.1	0.1	-4.0	-0.8	0.4	-0.5	-1.4	0.5	-1.4	0.8	1.0	0.2	0.4
Had menopause	0.6	0.7	2.2	1.1	0.7	0.6	1.0	-0.3	0.9	-1.0	-0.8	-1.5	-1.0	0.1	-1.3	0.4	0.1	0.8	0.1
Mouth/teeth dental problems	0.6	0.9	3.4	-0.1	1.8	-0.7	0.3	1.5	0.3	0.1	0.5	0.7	1.6	0.3	1.9	0.5	0.2	0.5	1.0
Allergy	0.6	1.4	5.7	0.4	0.5	0.1	1.0	0.1	2.4	0.2	-0.4	-2.3	-2.1	-1.2	-1.4	-0.6	0.2	0.6	-0.9
Impedance of arm (right)	0.6	2.7	26.9	-0.3	-0.3	-0.9	-0.9	2.6	5.2	-0.1	-0.5	0.4	2.1	0.7	1.4	0.3	-0.5	-0.2	0.7
Mouth/teeth dental problems: Dentures	0.6	1.1	3.4	-0.3	-1.8	-0.1	0.6	-1.4	0.6	1.5	0.9	-0.0	-1.8	-1.1	-0.5	-0.9	-0.8	0.7	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	4.5	-0.5	-0.1	-0.0	-1.1	-1.3	-2.1	0.1	0.5	1.4	0.2	-0.2	0.7	-0.1	-0.6	-0.9	0.1
Lung cancer (father)	0.6	0.7	1.7	0.5	-0.8	1.3	0.4	1.2	0.6	-1.1	-0.6	-0.8	0.1	0.9	-0.9	0.8	1.3	-0.4	0.8
Impedance of arm (left)	0.6	2.9	32.8	-0.4	0.4	-0.8	-0.6	2.5	5.7	-0.3	-0.5	0.4	1.9	0.7	1.0	0.2	-0.5	-0.3	0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	3.7	0.8	0.1	0.2	1.0	-1.2	-0.3	0.1	1.9	1.6	-0.2	0.0	0.8	0.3	0.4	0.4	0.5
Mean time to correctly identify matches	0.6	1.1	8.4	-0.9	-0.1	-0.7	0.1	0.3	2.9	1.4	1.2	1.0	-0.0	-0.8	1.3	-0.7	-0.8	0.3	-0.5
Age at last live birth	0.6	0.9	2.8	0.7	-1.2	1.7	-0.4	0.4	0.3	-1.5	-1.0	-0.6	0.4	1.2	-0.8	1.1	0.6	-0.7	1.1
Medication for cholesterol	0.6	0.9	4.1	-0.6	2.0	-0.7	1.0	-0.7	-1.4	0.1	0.2	1.2	0.5	-0.9	1.3	-0.2	-1.2	-1.0	0.3
Guilty feelings	0.6	1.0	3.6	0.2	1.0	0.5	0.6	-0.6	-0.5	-0.1	-0.1	1.5	1.9	1.2	1.2	1.3	0.2	0.4	1.5
Financial situation satisfaction	0.6	0.8	2.6	0.6	0.3	-0.4	-0.0	-0.7	-0.2	0.8	1.6	1.3	1.0	0.3	1.6	0.5	-0.4	1.2	0.8
High cholesterol (Self-reported)	0.6	1.1	5.2	0.5	1.0	-0.3	-0.1	-1.2	1.7	1.2	2.3	1.7	0.0	0.1	1.0	0.0	0.1	0.9	0.1
Risk taking	0.6	0.9	5.7	-0.3	-0.8	-0.7	-0.8	-0.2	-2.4	1.0	-1.0	0.5	1.6	0.5	1.0	0.4	-0.3	0.3	0.7
Unable to work because of sickness or disability	0.6	0.8	2.8	0.8	-0.5	0.5	0.2	1.7	1.1	-0.1	1.5	1.2	0.4	0.7	0.8	0.8	0.2	1.0	1.1
Basal cell carcinoma (self-reported)	0.6	0.7	2.0	0.1	0.7	0.6	1.1	1.0	-0.6	-0.9	-1.4	-1.3	1.1	0.8	-0.1	0.7	0.4	-0.6	0.7
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	-0.5	-1.1	-0.6	-1.1	-0.2	-1.6	0.7	-0.1	1.0	0.7	-0.1	1.0	-0.0	-0.4	0.4	0.3
BMI	0.5	3.1	23.4	0.9	-4.2	1.4	-0.3	-0.1	-4.8	-0.5	-0.2	-0.2	-0.9	0.8	-1.5	0.5	1.1	-0.2	0.2
Hypothyroidism (self reported)	0.5	1.2	5.6	0.9	-2.4	1.3	1.8	0.4	-0.5	-0.5	-0.6	-1.1	-0.2	0.6	-0.3	1.2	1.3	0.4	1.1
Respiratory disease	0.5	1.1	3.8	0.4	0.6	0.8	0.6	1.2	-1.0	-0.7	-0.7	0.5	2.0	1.8	0.5	1.4	1.0	-0.4	1.5
Lung FEV1/FVC ratio	0.5	2.6	12.9	0.7	-1.0	-1.4	0.3	2.3	-1.9	1.7	-0.0	1.2	3.6	1.2	2.1	0.9	0.4	1.7	1.2
Frequency of depressed mood in last 2 weeks	0.5	0.6	2.0	1.0	-0.0	0.6	0.0	-0.8	0.1	-0.7	-0.4	0.5	1.1	1.4	-0.1	1.0	1.0	1.2	0.8
Hearing difficulty/problems: Yes	0.5	0.8	3.0	-0.2	-1.0	0.9	-0.1	-0.4	-0.4	-1.1	-1.2	-1.0	-0.8	0.1	-1.7	-0.2	0.2	-1.6	-0.5
Medication for hormone replacement therapy	0.5	0.5	2.3	-0.2	-1.5	0.2	-1.2	1.1	-0.2	-0.0	-1.0	-0.6	-0.1	0.5	-0.8	0.1	0.7	0.2	-0.2
Current tobacco smoking	0.5	0.8	4.5	0.4	-2.1	-0.3	0.7	-0.3	1.3	1.5	1.6	0.7	-0.4	-0.3	0.5	-0.3	0.3	0.4	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.0	0.3	-1.3	1.3	-0.2	-1.2	-0.1	-1.4	-0.5	0.3	-0.6	0.6	-1.0	0.3	0.8	-0.6	0.1
Medication: Levothyroxine sodium	0.5	0.9	3.1	0.8	-1.3	0.5	1.4	0.0	-0.2	-0.3	-1.3	-1.8	-1.4	-0.4	-1.4	0.0	0.4	0.3	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.9	0.6	1.2	0.3	0.8	-0.5	0.1	-0.1	-1.0	0.2	1.7	1.2	0.7	1.2	0.4	0.8	1.3
Hearing difficulty/problems with background noise	0.5	0.8	2.8	-0.1	-1.7	0.4	-1.3	-0.7	0.5	-0.0	0.4	0.3	-1.5	-0.4	-1.3	-0.6	-0.1	-1.1	-0.9
Heart attack	0.5	0.7	1.5	-0.4	-1.2	-0.4	-1.0	0.3	-1.2	1.2	0.6	0.6	-0.7	-0.7	-0.5	-0.9	-0.9	-0.9	-1.0
Illnesses of siblings	0.5	0.7	1.6	1.3	1.2	0.6	0.8	0.2	0.7	-1.3	-0.4	-0.8	-0.3	0.6	-0.6	0.7	1.0	1.0	0.5
Hip circumference	0.5	2.1	25.2	-0.0	-1.4	1.1	0.4	0.5	-5.0	-0.6	0.7	0.8	-1.0	0.0	-0.8	0.1	-0.1	-1.2	-0.1
Worrier / anxious feelings	0.5	1.0	4.4	-0.3	1.3	0.1	-0.0	0.6	-1.4	-0.1	0.6	2.1	1.7	0.7	1.5	0.5	-0.5	-0.6	1.0
Pulse rate	0.5	0.8	2.0	-1.1	0.1	0.0	-0.2	0.4	0.6	0.3	0.5	-0.6	-1.4	-1.1	-0.9	-1.1	-1.4	-1.4	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.2	-0.4	-1.5	0.4	-1.3	-0.5	-0.4	-0.3	0.3	1.3	0.6	0.7	0.3	0.4	0.2	-1.0	0.6
Asthma	0.5	1.0	2.7	0.6	0.3	1.0	1.3	1.1	-0.5	-1.0	-0.7	0.1	1.6	1.6	0.4	1.4	0.9	-0.3	1.6
Prospective memory result	0.5	0.6	1.5	0.5	0.1	0.3	0.9	-0.6	-0.4	0.2	1.1	1.0	0.8	0.7	1.0	0.8	0.5	1.2	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	14.7	-0.2	1.1	-1.3	-0.3	-0.6	-3.8	1.5	0.4	0.4	0.7	-0.7	1.0	-0.4	-1.3	0.5	-0.3
Pulse wave Arterial Stiffness index	0.5	0.6	3.3	-0.8	1.0	0.6	0.4	0.7	-1.1	-0.7	-0.1	0.6	-0.6	-0.3	-0.6	-0.3	-0.4	-1.8	-0.1
Arm fat mass (right)	0.5	2.1	17.9	1.0	-2.6	1.4	1.0	0.4	-4.2	-0.6	0.5	0.2	-0.6	0.7	-0.6	0.9	0.7	0.1	0.8
Standing height	0.5	5.4	41.3	-0.9	3.1	-1.3	-0.2	-1.8	-6.4	1.4	1.9	3.4	1.1	-0.7	2.7	-0.3	-1.5	-0.8	0.4
Exposure to tobacco smoke at home	0.5	0.5	1.9	0.1	0.1	0.6	0.2	-0.4	1.0	-0.4	-1.1	-1.4	-1.4	-0.5	-1.3	-0.1	0.2	-0.4	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.4	-0.7	1.2	-0.2	-1.0	1.6	0.8	-0.3	0.1	0.8	1.2	0.3	1.3	0.3	-0.4	-0.8	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.5	0.6	0.3	0.7	0.4	0.8	1.2	-0.9	-0.9	-0.2	0.8	1.1	-0.5	0.9	0.9	0.5	0.7
Pulse wave peak to peak time	0.5	0.6	3.5	0.8	-0.8	-0.8	-0.5	-1.0	0.5	0.9	0.1	-0.5	0.7	0.2	0.7	0.2	0.3	1.9	0.1
Shortness of breath walking on level ground	0.5	0.6	1.9	0.3	-1.2	-0.3	0.2	0.4	-1.1	0.6	1.0	0.8	0.8	0.1	1.4	0.4	-0.2	1.0	0.6
Angina (self-reported)	0.5	0.7	3.1	-0.2	1.0	-0.7	-0.7	0.5	-0.2	1.0	0.9	1.8	1.1	0.1	1.0	-0.2	-0.9	-0.4	-0.0
Medication: Ibuprofen	0.5	0.6	4.6	-0.4	0.4	-0.2	-0.8	-0.9	-2.1	0.0	0.2	1.0	0.3	-0.2	0.7	-0.2	-0.6	-0.6	0.0
Medication: Omeprazole	0.5	0.6	4.8	-0.1	-0.5	0.2	0.1	0.7	-2.2	-0.1	-0.1	0.7	1.1	0.8	0.5	0.6	0.3	0.4	0.7
Medication: Seretide 50 evohaler	0.5	0.6	1.7	0.7	-0.6	1.3	0.6	-0.2	0.2	-1.0	-1.3	-0.4	0.6	0.9	-0.2	1.1	0.0	-0.6	1.2
Leg fat mass (right)	0.5	1.8	16.4	0.5	-2.8	0.6	1.1	0.5	-4.0	0.2	0.9	0.6	-0.1	0.3	0.3	0.5	0.4	0.1	0.6
Supplements: Vitamin C	0.5	0.5	2.2	-0.6	1.0	0.2	0.5	0.2	0.2	-0.8	0.7	1.5	1.0	0.4	1.1	0.0	-0.0	-0.9	0.3
Handedness (chirality/laterality): Left-handed	0.5	0.7	3.3	0.3	-0.8	0.2	-0.3	-1.1	0.3	-0.1	-1.2	-1.8	-0.9	-0.1	-1.2	0.1	0.0	1.2	-0.2
Back pain experienced in last month	0.5	0.8	4.8	0.3	-1.7	0.5	-0.3	0.2	-2.2	-0.1	-0.7	-0.4	0.9	0.6	0.0	0.6	-0.1	-1.2	0.6
Asthma (self-reported)	0.5	1.0	2.4	0.5	0.5	1.1	1.0	0.9	-0.6	-1.1	-0.8	0.0	1.5	1.6	0.2	1.4	0.9	-0.4	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	3.1	1.4	0.3	0.3	1.2	1.3	-1.1	-0.6	-0.7	-0.6	1.3	1.2	0.1	1.3	0.8	1.7	1.2
Arm fat mass (left)	0.5	2.0	17.2	0.9	-2.5	1.4	1.0	0.4	-4.1	-0.6	0.5	0.1	-0.8	0.6	-0.7	0.8	0.7	0.0	0.7
Miserableness	0.5	0.8	3.0	0.2	1.3	-0.0	0.1	0.7	1.7	-0.1	0.3	0.8	1.7	0.8	1.4	0.7	0.0	0.6	0.8
Medication: Paracetamol	0.5	0.9	5.8	0.1	-2.4	0.2	0.5	1.1	0.0	0.7	1.4	1.6	0.3	0.1	1.1	0.1	0.1	-0.3	0.4
Medication: Lisinopril	0.5	0.6	3.7	-1.0	0.5	-0.9	-1.9	-0.5	-0.2	0.5	-0.4	-0.0	0.0	-0.4	-0.3	-1.0	-0.4	-1.0	-0.9
Medication: Atorvastatin	0.5	0.7	1.3	1.1	-1.1	0.7	0.9	0.9	0.6	-0.1	0.5	0.5	0.5	1.1	0.1	1.0	1.1	0.9	0.8
Ever smoked	0.5	0.8	2.5	-0.4	-0.3	-0.8	-0.1	-1.0	-0.3	1.2	1.2	1.6	-1.1	-1.2	0.5	-1.1	-0.1	0.1	-1.1
Commuting to job workplace: Cycle	0.5	0.6	1.6	-0.2	-0.7	-1.1	-0.5	-1.1	-0.4	1.2	0.5	0.9	1.3	0.1	1.2	-0.2	-0.1	-0.0	-0.0
Supplements: Calcium	0.5	0.6	1.6	-1.3	0.7	-0.4	-0.6	-1.3	-0.8	-0.2	-0.0	0.4	-0.5	-0.8	0.1	-0.8	-1.0	-1.1	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.8	-0.4	-0.3	0.5	-0.9	-0.7	-0.7	-0.6	1.4	1.7	-0.6	-0.2	0.0	-0.3	0.0	-1.2	-0.3
Neuroticism (Nagel 2018)	0.4	0.8	2.0	0.2	1.4	1.2	0.2	0.9	0.7	-1.1	-1.3	-0.2	1.0	1.2	-0.4	1.1	0.1	-0.3	1.1
Schizophrenia vs Biploar Disorder	0.4	0.6	2.4	0.4	0.6	1.3	0.8	0.7	0.3	-1.5	-0.1	-0.4	-0.2	0.8	-0.9	0.7	1.0	-0.6	0.4
Worry (Nagel 2018)	0.4	0.8	2.3	0.1	1.5	1.4	0.7	1.1	0.8	-1.2	-1.1	-0.3	0.4	0.9	-0.7	1.0	-0.1	-0.8	1.0
Alzheimer’s Disease (in father)	0.4	0.4	2.4	-0.5	1.5	-0.5	-0.1	0.3	-0.1	0.5	0.9	1.0	0.3	-0.4	1.1	-0.3	-0.3	-0.5	-0.1
Mean Putamen Volume	0.4	0.4	1.4	0.2	0.8	0.4	0.8	1.2	-0.7	-0.4	0.9	0.1	0.4	0.6	0.4	0.6	0.5	0.6	0.7
Neuroticism (2016)	0.4	0.6	2.0	0.0	-0.7	0.3	-0.4	0.2	1.4	-0.1	0.8	1.3	1.2	0.9	0.7	0.5	0.1	0.2	0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	3.0	-0.5	1.0	-0.0	0.3	0.5	-0.5	0.3	0.6	1.7	0.8	0.3	0.8	0.1	-0.3	-0.4	0.3
Supplements: Zinc	0.4	0.4	1.7	-0.6	1.3	-0.4	1.0	0.0	0.8	0.5	0.8	0.2	0.2	-0.5	0.9	-0.3	-0.2	-0.3	-0.2
Severe depression (siblings)	0.4	0.5	1.6	-0.4	-1.3	-0.8	-0.9	0.2	-0.3	0.8	-1.3	-0.7	0.9	0.3	-0.2	-0.3	0.3	-0.2	-0.3
Trunk fat percentage	0.4	1.6	8.4	0.9	-2.9	1.2	1.2	2.2	-1.0	-0.7	0.2	0.5	0.8	1.3	0.2	1.4	0.8	0.2	1.5
Maternal smoking around birth	0.4	0.6	1.8	-0.7	-0.5	-1.3	-0.3	-0.4	-0.8	1.3	0.9	0.6	0.3	-0.7	1.1	-0.9	-0.5	0.4	-0.8
Serious illness, injury or assault to yourself	0.4	0.4	1.4	-0.8	0.7	-0.4	-0.1	-0.6	-0.9	0.1	0.1	1.1	0.2	-0.4	0.2	-0.6	-1.0	-1.2	-0.4
Chronic bronchitis/emphysema (father)	0.4	0.5	2.3	-0.1	0.5	1.0	1.0	0.0	-0.1	-1.4	-0.2	-0.1	-0.3	-0.0	-0.2	0.4	-0.4	-1.5	0.4
Trunk fat mass	0.4	1.7	11.9	0.8	-2.3	1.2	1.2	1.0	-3.5	-0.5	0.7	0.8	0.3	0.9	0.2	1.2	0.6	-0.1	1.3
Nervous feelings	0.4	0.8	3.1	-0.5	1.7	-0.2	0.1	0.4	1.8	0.3	0.8	1.4	0.5	-0.4	0.9	-0.1	-1.5	-0.5	0.2
Forced vital capacity (FVC)	0.4	1.6	13.3	-0.3	2.5	-0.6	-0.4	-1.3	-3.7	0.8	0.6	0.2	-0.5	-0.9	0.5	-0.4	-1.3	0.2	-0.3
Arm fat percentage (right)	0.4	1.5	12.4	0.8	-3.5	1.4	0.7	1.3	-1.7	-0.8	0.4	-0.0	-0.7	0.7	-0.8	0.8	0.8	-0.1	0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	13.3	0.1	1.8	-1.0	0.0	-0.8	-3.6	1.4	0.6	0.4	0.5	-0.5	1.1	-0.1	-0.9	1.0	0.0
Medication: Cholesterol lowering	0.4	0.7	1.6	-0.9	0.6	-0.6	-0.6	-1.3	0.1	1.0	0.6	0.6	-1.0	-1.1	-0.1	-1.0	-1.1	-0.7	-0.9
Breastfed as a baby	0.4	0.5	1.8	0.4	0.2	0.9	-0.1	-0.7	-0.8	-1.1	-0.2	0.1	0.7	0.9	-0.2	0.6	0.4	-1.4	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.4	0.1	1.4	0.8	0.8	0.9	1.5	-0.8	-0.0	0.8	0.6	0.7	0.2	0.7	0.4	-0.1	0.8
Hair/balding pattern: Pattern 4	0.4	0.9	2.9	-0.7	-0.1	-1.4	-0.6	0.4	-1.4	1.7	-0.7	0.8	1.7	-0.2	1.6	-0.2	-0.8	-0.5	0.2
Peak expiratory flow (PEF)	0.4	1.0	6.8	-0.2	-0.4	-0.9	-0.7	-0.6	-2.6	2.0	0.3	0.6	0.8	-0.4	1.1	-0.2	-0.9	0.6	-0.1
Pulse wave reflection index	0.4	0.5	2.6	0.0	-0.1	0.4	-0.6	-1.2	-1.2	-0.5	0.3	0.0	-1.6	-0.5	-1.2	-0.4	-0.0	-0.5	-0.6
Blood clot in the leg (DVT)	0.4	0.5	2.2	-0.1	-0.3	0.8	-0.7	-0.7	-0.7	-0.7	1.3	1.5	-0.8	-0.0	-0.1	-0.1	0.2	-1.1	-0.1
Medication: Paracetamol	0.4	0.7	4.0	0.1	-2.0	0.8	0.3	0.4	0.2	0.1	1.8	1.4	-0.7	-0.2	0.4	-0.1	0.0	-0.9	0.1
Birth weight	0.4	0.9	4.2	-1.1	1.1	-1.0	0.6	-0.7	-0.4	0.7	0.7	1.6	1.4	-0.4	2.0	-0.3	-0.9	-0.3	0.2
Forced vital capacity (FVC), Best measure	0.4	1.6	15.3	-0.5	1.5	-0.9	-0.5	-0.9	-3.9	1.0	0.6	0.4	0.1	-0.9	0.7	-0.6	-1.6	-0.2	-0.4
Medication for pain relief, constipation, heartburn	0.4	0.7	4.1	0.1	1.3	-0.5	-0.2	-0.2	2.0	-0.4	-1.0	-1.6	-0.4	-0.3	-0.7	-0.3	-0.1	0.8	-0.6
Heart disease (mother)	0.4	0.5	2.0	-0.6	-1.2	1.0	-0.3	-0.4	0.2	-1.0	-1.0	-0.1	-0.4	0.4	-1.0	0.1	0.4	-1.4	0.2
Whole body fat mass	0.4	1.9	15.4	0.8	-2.6	1.0	0.9	0.8	-3.9	-0.3	0.8	0.9	0.3	0.8	0.3	1.0	0.5	0.0	1.1
Chest pain or discomfort	0.4	0.5	2.0	0.0	-0.4	-0.3	0.4	-0.9	0.2	0.6	0.9	-0.2	-1.4	-1.1	-0.3	-0.8	-0.9	-0.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.7	0.3	-0.2	-0.5	0.1	0.6	-0.0	0.7	0.5	1.3	1.2	0.2	1.2	0.3	-0.3	0.5	0.5
Illnesses of siblings: Diabetes	0.4	0.5	2.2	-0.3	-0.7	0.1	0.1	-0.5	-0.4	0.0	0.0	1.1	1.5	0.5	1.1	0.6	0.5	-0.5	0.9
Arm fat percentage (left)	0.4	1.5	11.0	0.9	-3.3	1.5	0.8	1.2	-1.6	-0.9	0.3	-0.1	-0.7	0.7	-1.0	0.9	0.8	-0.1	0.7
Loneliness, isolation	0.4	0.5	2.2	0.6	-0.2	1.5	-0.1	-1.1	-0.3	-1.4	-0.3	0.1	-0.3	0.7	-0.7	0.7	0.5	-0.6	0.6
Ever had bowel cancer screening	0.4	0.5	1.6	-0.0	0.3	1.1	0.8	1.1	-1.0	-1.0	0.2	0.2	-0.6	0.1	-0.4	0.4	-0.1	-1.3	0.5
Mineral and other dietary supplements	0.4	0.6	1.8	-0.2	-0.7	-0.7	0.0	0.5	-0.0	1.2	-0.0	0.1	-1.3	-1.1	-0.7	-0.9	-0.9	0.5	-1.2
Osteoporosis (self-reported)	0.4	0.5	3.6	-0.2	-1.2	-0.3	-0.1	-0.2	-1.9	0.4	0.4	-0.3	-0.7	-0.7	-0.4	-0.7	-0.6	-0.3	-1.0
Average weekly champagne plus white wine intake	0.4	0.6	2.0	-0.6	1.1	-0.6	-0.9	-0.8	-0.5	0.5	1.4	0.5	-0.8	-0.9	0.5	-1.0	-0.3	0.0	-1.0
Ever taken oral contraceptive pill	0.4	0.4	1.7	-1.1	1.3	-0.3	-0.0	-1.2	-0.1	-0.2	0.2	0.9	0.1	-0.3	0.6	-0.3	-0.3	-1.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.7	-0.0	0.5	0.3	0.2	0.4	-0.8	-0.6	-0.3	0.0	1.6	1.2	0.7	0.8	0.9	-0.2	1.0
Leg fat percentage (left)	0.4	1.3	11.6	-0.1	-3.4	-0.0	0.8	1.9	-1.1	0.6	0.8	0.8	0.7	0.3	0.8	0.2	0.2	-0.2	0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.5	-0.4	-0.5	0.1	-1.6	-0.2	-1.1	-0.3	-0.0	0.3	-0.7	-0.3	-0.4	-0.6	-0.5	-1.2	-0.5
Myopia	0.4	0.6	2.0	-0.2	0.4	-1.4	-0.8	-1.0	-0.1	1.2	0.5	0.2	-0.0	-0.8	0.8	-0.7	-0.5	1.0	-0.8
Pain experienced in last month	0.4	0.7	3.0	-0.8	1.6	-1.7	0.3	0.2	0.0	1.0	-0.2	-0.4	0.4	-0.9	1.0	-0.8	-0.5	0.8	-0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.8	-0.2	-1.4	-0.2	-0.8	0.4	-1.1	1.3	0.7	0.6	-0.6	-0.5	-0.3	-0.7	-0.6	-0.7	-0.8
Leg fat mass (left)	0.4	1.7	15.5	0.4	-2.8	0.6	0.9	0.7	-3.9	0.1	0.8	0.8	0.2	0.5	0.3	0.6	0.4	-0.1	0.7
Bipolar Disorder or Schizophrenia	0.3	0.8	1.6	-1.1	1.0	-1.3	-1.2	-0.6	0.4	1.1	0.6	1.2	0.1	-0.7	0.4	-1.1	-1.0	-0.3	-1.1
Depression (Nagel 2018)	0.3	0.5	1.3	0.1	-0.1	0.7	-0.1	-0.9	-1.1	-1.0	-0.6	0.8	0.8	1.2	-0.3	0.6	1.0	0.2	0.6
Primary Biliary Cirrhosis	0.3	0.4	2.0	0.2	0.2	0.7	-0.4	0.1	0.3	-1.4	-0.6	-0.4	-0.8	0.2	-1.4	-0.1	-0.4	-0.5	-0.3
Blood White Count	0.3	2.1	9.1	-1.7	-1.9	-1.5	-0.6	0.3	-3.0	2.2	-0.8	-0.1	0.7	-1.1	0.7	-1.0	-2.1	-1.5	-0.7
Average weekly spirits intake	0.3	0.3	0.7	-0.7	-0.2	-0.8	-0.4	-0.2	0.3	0.4	0.6	0.8	-0.3	-0.8	0.5	-0.8	-0.7	-0.1	-0.6
Sensitivity / hurt feelings	0.3	0.6	2.3	-0.6	0.9	0.3	-0.3	-0.5	-0.2	-0.1	-0.2	1.4	1.5	0.8	0.8	0.5	-0.2	-1.1	0.8
Relative age of first facial hair	0.3	0.7	4.1	0.2	0.9	0.1	-0.4	-1.6	-0.9	-0.8	-2.0	-0.9	0.5	0.5	-0.8	0.3	-0.4	-0.1	0.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	0.4	-0.9	0.4	0.6	1.1	-0.5	-0.3	-1.2	-0.4	0.6	0.7	-0.2	0.8	0.6	0.1	0.6
Angina	0.3	0.4	2.2	0.1	0.7	-0.4	-0.6	0.5	-0.0	0.8	0.9	1.5	0.9	0.4	0.7	0.1	-0.5	-0.1	0.2
Pack years adult smoking proportion	0.3	0.4	1.1	0.1	-0.9	-0.3	-0.7	-0.0	-0.9	0.7	1.0	1.1	0.4	0.0	1.0	-0.1	0.1	0.1	0.0
Average weekly fortified wine intake	0.3	0.4	2.4	-0.6	-0.3	-0.2	-0.4	0.1	1.5	0.1	0.6	0.2	-0.8	-0.8	0.0	-0.7	-0.5	-0.8	-0.6
Relative age voice broke	0.3	0.5	1.5	0.9	0.9	0.9	1.2	-0.9	0.2	-0.4	-0.5	0.0	0.2	0.6	-0.1	1.1	0.4	0.1	1.1
Age when periods started (menarche)	0.3	0.7	1.9	-0.4	1.1	0.0	1.1	0.4	1.0	-1.0	-0.7	-0.9	-0.8	-0.5	-1.0	-0.6	0.2	-1.4	-0.8
Medication: Atenolol	0.3	0.4	1.7	0.5	-0.7	0.7	-0.1	1.3	1.1	-0.2	0.9	0.1	-0.2	0.6	-0.5	0.4	1.0	0.3	0.3
Past tobacco smoking	0.3	0.6	2.2	-0.0	0.7	0.0	0.0	0.5	0.3	-0.6	-1.4	-1.4	1.5	0.7	-0.1	0.7	-0.6	-0.5	0.7
Medication: Simvastatin	0.3	0.4	4.0	0.3	2.0	-0.2	-0.3	-1.1	0.8	0.2	0.5	0.5	0.1	0.2	0.2	0.1	0.2	0.5	0.1
Neuroticism score	0.3	0.5	1.8	0.1	0.8	0.8	0.2	-0.1	0.3	-0.5	-0.2	1.0	1.3	1.0	0.5	1.0	-0.1	-0.4	1.2
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	2.9	0.7	-0.1	0.2	-1.7	-1.0	-0.4	-0.5	-0.3	0.5	0.2	0.4	-0.2	0.3	0.2	0.2	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.7	0.5	-1.6	0.7	1.3	0.1	-0.2	-0.1	-0.6	-1.0	-1.1	-0.4	-0.7	0.2	0.3	0.3	-0.0
High blood pressure (siblings)	0.3	0.4	1.6	-0.3	-1.2	0.6	-0.8	-0.3	0.6	0.0	-0.6	-0.8	-0.7	0.2	-1.2	-0.1	0.4	-0.2	-0.3
Body fat percentage	0.3	1.3	9.6	0.5	-3.1	0.8	1.1	2.0	-1.2	-0.3	0.4	0.5	0.6	0.8	0.3	1.0	0.5	-0.0	1.1
Leg fat percentage (right)	0.3	1.2	11.7	-0.0	-3.4	-0.1	1.2	1.5	-1.2	0.7	0.9	0.6	0.3	-0.0	0.8	0.1	0.2	0.2	0.3
Number of full brothers	0.3	0.4	2.5	0.3	-0.9	0.1	0.9	-1.1	1.6	0.6	0.3	-0.0	-0.3	-0.3	0.1	0.1	-0.1	0.6	0.0
Emphysema/chronic bronchitis	0.3	0.4	1.4	-0.4	-0.2	-0.1	-0.5	-1.2	0.9	-0.2	1.1	0.0	-0.9	-0.5	-0.3	-0.5	-0.0	-0.6	-0.5
Medication: Blood pressure	0.3	0.5	2.6	-0.3	-1.0	-0.7	-0.7	-0.9	0.1	1.6	0.9	0.2	0.1	-0.3	0.5	-0.4	-0.4	0.5	-0.4
Pulse rate, automated reading	0.3	0.9	2.8	-0.7	-0.0	-0.3	-0.6	0.2	0.4	0.8	-0.2	-1.4	-1.7	-1.3	-1.3	-1.1	-1.2	-0.6	-1.2
Medication: Aspirin	0.3	0.4	2.4	-0.6	-0.3	-0.8	-0.4	-0.3	-0.0	1.5	0.7	0.6	-0.3	-0.7	-0.0	-0.8	-0.2	-0.3	-0.9
Breast cancer (self-reported)	0.3	0.4	1.6	0.6	-0.6	0.5	-0.4	0.2	-0.6	-0.5	-0.6	-1.1	-1.0	-0.0	-1.2	0.0	0.4	0.2	-0.3
Wears glasses or contact lenses	0.3	0.4	1.0	-0.4	0.6	-0.5	0.3	0.4	-0.2	0.3	0.5	0.6	-1.0	-1.0	-0.0	-0.9	-0.8	0.1	-0.9
Mother’s age at death	0.3	0.3	1.3	0.2	0.8	-0.6	0.4	0.1	-1.0	0.5	0.4	0.4	0.4	-0.5	1.1	-0.1	-0.7	0.7	0.1
Commuting to job workplace: Public transport	0.3	0.4	1.8	0.2	-0.1	-0.3	-0.1	0.4	-0.3	1.4	0.5	0.8	0.9	0.2	1.1	0.4	-0.2	0.6	0.7
Pack years of smoking	0.3	0.5	2.1	-0.0	-0.5	-0.4	-0.7	-0.1	-1.1	0.6	1.2	1.5	0.4	-0.1	1.1	-0.3	-0.2	-0.2	-0.1
Depressed Affect (Nagel 2018)	0.2	0.4	2.4	-0.6	0.2	0.3	-0.9	0.0	0.6	-0.6	-1.5	-0.6	0.0	0.1	-0.7	-0.0	-0.4	-0.4	-0.1
Body Mass Index (BMI) (2010)	0.2	0.2	1.2	0.2	-0.9	0.1	-0.1	-1.1	-0.6	0.4	0.4	0.4	-0.3	-0.3	-0.1	-0.3	0.1	-0.5	-0.4
Fasting Glucose	0.2	0.2	1.0	0.5	-0.1	-0.7	-0.9	-0.1	-0.3	0.5	0.6	0.4	0.2	-0.1	0.3	-0.1	-0.2	1.0	-0.5
Neuroticism	0.2	0.4	2.4	-0.3	1.6	0.5	-0.7	0.1	-0.4	-0.3	-0.6	0.9	0.9	0.8	-0.1	0.5	-0.5	-0.4	0.6
Tanning	0.2	2.1	8.3	1.6	1.9	2.2	1.0	1.8	-0.0	-2.9	-0.8	-0.4	-0.0	1.6	-1.1	1.6	1.3	-0.1	1.4
Fed-up feelings	0.2	0.4	1.8	-0.3	-0.8	-0.5	-0.6	-1.1	0.2	1.4	0.8	0.5	-0.1	-0.5	0.7	-0.4	-0.5	0.7	-0.4
Taking other prescription medications	0.2	0.3	1.3	-0.3	0.7	0.4	0.1	0.5	-1.1	-0.1	0.1	0.4	-0.7	-0.2	-0.4	-0.2	-0.0	-1.0	-0.1
Financial difficulties in last 2 years	0.2	0.3	1.4	0.2	-0.5	0.0	0.7	0.0	0.2	0.4	0.2	-0.6	-1.2	-0.6	-0.7	-0.5	-1.1	-0.1	-0.5
Number of live births	0.2	0.3	0.8	-0.0	-0.8	0.1	0.3	-0.9	0.4	-0.0	-0.1	-0.2	-0.8	-0.3	-0.9	-0.5	-0.4	-0.2	-0.8
Medication: Lansoprazole	0.2	0.2	1.2	0.2	1.0	0.1	1.1	-0.1	-1.1	0.2	0.1	0.1	-0.1	0.1	-0.1	0.2	0.4	-0.1	0.1
Tense / ‘highly strung’	0.2	0.4	3.1	-0.5	0.4	0.9	0.1	0.1	0.7	-0.6	-0.1	0.4	0.1	0.2	-0.3	0.2	-0.5	-1.8	0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.5	0.2	0.8	0.2	0.5	0.6	-1.2	-0.8	-0.7	0.0	1.0	0.5	0.5	0.6	0.1	-0.1	0.7
Exposure to tobacco smoke outside home	0.2	0.3	1.5	0.0	-1.2	-0.3	0.1	-0.6	-0.6	0.5	-0.7	-0.6	-0.5	-0.7	-0.1	-0.3	-0.7	-0.1	-0.3
Overall health rating	0.2	0.5	4.2	-0.1	-2.0	0.3	-1.1	0.9	-0.7	0.4	-0.5	-0.0	-0.1	0.2	-0.6	0.1	-0.4	-0.5	0.1
Smoking status: Previous	0.2	0.3	1.2	-0.2	-0.1	-0.0	-0.1	-0.4	-1.1	0.2	0.8	1.1	-1.0	-0.5	0.1	-0.5	0.5	0.2	-0.4
Mood swings	0.2	0.3	0.8	-0.1	0.2	0.8	0.2	0.8	0.5	-0.7	-0.9	-0.1	0.8	0.7	-0.1	0.7	-0.2	-0.7	0.7
Schizophrenia (2018)	0.1	0.2	0.9	-0.7	0.8	-0.1	-0.1	0.2	1.0	-0.1	0.1	0.8	0.4	0.1	-0.3	-0.3	0.1	-0.8	-0.3
Schizophrenia (2014)	0.1	0.2	0.6	-0.3	0.8	-0.1	-0.2	-0.4	0.7	-0.2	-0.1	0.4	0.7	0.4	-0.2	0.1	0.4	-0.4	-0.0
Lung FVC	0.1	0.8	3.7	-0.5	1.9	0.1	-1.6	-0.7	-1.7	-0.5	0.2	0.0	-0.5	-0.4	-0.1	-0.3	-1.2	-0.5	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.8	0.1	-0.1	-0.5	0.4	-0.1	-0.7	0.4	0.3	0.1	0.3	-0.0	0.5	-0.0	0.3	0.9	0.0
Average weekly red wine intake	0.1	0.1	0.6	-0.3	-0.7	-0.0	-0.5	0.0	0.3	-0.1	-0.2	-0.0	0.2	-0.0	0.1	-0.0	0.4	-0.2	-0.0
Number of self-reported non-cancer illnesses	0.1	0.2	1.3	0.6	0.3	0.5	-0.1	-0.4	-0.2	0.0	1.1	0.9	-0.2	0.5	-0.1	0.1	0.4	0.0	0.2
Average weekly beer plus cider intake	0.1	0.2	0.8	0.5	0.1	0.6	0.5	-0.0	-0.2	-0.1	0.6	-0.0	0.3	0.5	0.4	0.8	0.3	0.2	0.9
Fractured/broken bones in last 5 years	0.1	0.2	0.6	0.0	-0.1	-0.2	0.8	0.7	-0.8	0.1	-0.3	-0.6	0.2	-0.0	0.0	0.1	-0.1	0.5	-0.0
Hair Pigment	0.0	0.5	5.3	0.2	-1.1	-0.4	0.3	-0.3	-2.3	0.6	-0.2	-0.0	0.8	0.2	0.5	0.1	-0.3	0.6	-0.2

Hub : Genes

GIMAP4

Models

Trait associations