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chr11:64,954,053-68,077,666

Best TWAS P=8.94e-11 · Best GWAS P=1.15e-13 conditioned to 0.351

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	4.1	5.7	1.6e-08	-0.33	1.00	0.00	TRUE
2	GTEx	Adipose Visceral Omentum	RPS6KB2	0.08	0.03	lasso	8	0.04	2.9e-03	-5.0	5.2	1.7e-07	-0.26	0.03	0.94	FALSE
3	GTEx	Adipose Visceral Omentum	AP003419.16	0.09	0.05	enet	8	0.04	4.6e-03	-5.0	5.2	2.4e-07	-0.28	0.02	0.94	FALSE
4	GTEx	Brain Cerebellar Hemisphere	GSTP1	0.25	0.15	enet	16	0.20	8.7e-06	-4.3	5.2	1.8e-07	-0.23	0.09	0.87	FALSE
5	GTEx	Brain Cerebellar Hemisphere	PTPRCAP	0.39	0.43	lasso	8	0.47	7.7e-14	-5.1	5.1	2.7e-07	-0.28	0.02	0.98	FALSE
6	GTEx	Brain Cerebellum	NDUFV1	0.19	0.01	enet	29	0.05	1.7e-02	4.0	-5.3	1.4e-07	0.20	0.04	0.34	FALSE
7	GTEx	Brain Frontal Cortex BA9	PTPRCAP	0.21	0.11	enet	15	0.15	9.6e-05	-5.0	5.2	1.6e-07	-0.29	0.02	0.96	FALSE
8	GTEx	Breast Mammary Tissue (Male)	GSTP1	0.11	-0.01	lasso	2	-0.01	7.7e-01	-4.6	5.4	8.0e-08	-0.21	0.02	0.18	FALSE
9	GTEx	Cells Transformed fibroblasts	AP003419.16	0.21	0.22	lasso	6	0.21	1.6e-15	-5.0	5.1	2.8e-07	-0.28	0.04	0.96	FALSE
10	GTEx	Esophagus Muscularis	CTD-3074O7.5	0.22	0.02	enet	17	0.09	3.7e-06	-2.9	6.5	8.9e-11	-0.50	0.25	0.54	TRUE
11	GTEx	Heart Atrial Appendage	RPS6KB2	0.16	0.09	lasso	9	0.07	3.5e-04	-5.0	5.2	2.3e-07	-0.28	0.04	0.93	FALSE
12	GTEx	Heart Atrial Appendage	PTPRCAP	0.14	0.11	lasso	10	0.09	5.1e-05	-5.0	5.7	1.1e-08	-0.29	0.04	0.94	TRUE
13	GTEx	Muscle Skeletal	PTPRCAP	0.09	0.08	lasso	6	0.09	2.6e-09	-4.9	5.1	3.0e-07	-0.27	0.05	0.94	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	AP003419.16	0.15	0.08	lasso	5	0.08	6.2e-05	-5.1	5.5	3.5e-08	-0.27	0.02	0.97	FALSE
15	GTEx	Testis	AIP	0.11	0.14	lasso	2	0.11	1.5e-05	-5.0	5.2	2.6e-07	-0.27	0.04	0.95	FALSE
16	GTEx	Testis	RPS6KB2	0.20	0.16	lasso	11	0.16	8.3e-08	-5.0	5.1	3.0e-07	-0.29	0.03	0.97	FALSE
17	GTEx	Thyroid	PACS1	0.09	0.04	enet	16	0.09	2.8e-07	-7.4	-5.2	2.5e-07	0.81	0.01	0.99	FALSE
18	GTEx	Vagina	PTPRCAP	0.33	0.05	enet	8	0.06	2.0e-02	-4.9	5.3	1.2e-07	-0.29	0.02	0.80	FALSE
19	METSIM	Adipose	GSTP1	0.05	0.05	lasso	6	0.04	9.3e-07	-5.1	5.1	2.8e-07	-0.22	0.05	0.95	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	CDK2AP2	0.03	0.02	enet	11	0.03	1.6e-04	-4.4	5.4	5.2e-08	-0.22	0.09	0.86	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CNIH2	0.03	0.00	enet	4	0.02	6.4e-03	-4.7	5.3	1.1e-07	-0.58	0.06	0.12	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS6KB2	0.05	0.07	lasso	4	0.06	6.2e-08	-5.1	5.2	1.8e-07	-0.29	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SNX32	0.30	0.19	lasso	1	0.14	3.9e-06	5.2	5.2	2.2e-07	-0.14	0.01	0.98	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS6KB2	0.09	0.13	lasso	6	0.13	7.1e-14	-5.0	5.2	2.1e-07	-0.26	0.01	0.98	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	SNX32	0.12	0.13	blup	60	0.13	1.2e-09	4.2	5.5	3.1e-08	-0.18	0.21	0.76	FALSE
26	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS6KB2	0.12	0.06	blup	35	0.05	5.4e-03	-5.1	5.5	3.2e-08	-0.28	0.01	0.77	FALSE