[Hub]/) : Traits : Whole body fat mass : ← →

chr17:65,123,352-66,885,526

Best TWAS P=2.52e-23 · Best GWAS P=7.5e-24 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
31	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf58	0.02	0.02	lasso	2	0.01	1.8e-02	9.9	10.0	2.5e-23	1.00	0.00	0.76	TRUE
8	GTEx	Brain Cortex	C17orf58	0.34	0.09	lasso	6	0.13	2.4e-04	9.9	9.5	2.2e-21	0.95	0.03	0.96	FALSE
11	GTEx	Cells Transformed fibroblasts	SH3GL1P3	0.26	0.31	lasso	7	0.31	1.5e-23	8.5	9.3	2.0e-20	0.90	1.00	0.00	FALSE
28	YFS	Blood	KPNA2	0.01	0.01	blup	312	0.01	2.8e-04	8.7	-9.2	4.2e-20	-0.86	0.05	0.93	FALSE
9	GTEx	Cells Transformed fibroblasts	LINC00674	0.30	0.31	enet	10	0.32	1.5e-24	8.5	9.1	7.7e-20	0.86	1.00	0.00	FALSE
7	GTEx	Brain Cerebellum	BPTF	0.22	-0.01	lasso	10	-0.01	6.9e-01	8.2	-8.7	2.4e-18	-0.85	0.04	0.48	FALSE
10	GTEx	Cells Transformed fibroblasts	LRRC37A16P	0.50	0.46	lasso	8	0.47	1.1e-38	8.5	8.7	3.6e-18	0.84	1.00	0.00	FALSE
21	GTEx	Nerve Tibial	LRRC37A16P	0.09	0.08	lasso	4	0.06	2.7e-05	8.5	8.6	5.2e-18	0.84	0.10	0.78	FALSE
1	GTEx	Adipose Subcutaneous	LINC00674	0.12	0.13	enet	6	0.14	9.9e-12	8.5	8.4	3.5e-17	0.79	0.96	0.04	FALSE
3	GTEx	Adipose Subcutaneous	SH3GL1P3	0.08	0.06	lasso	5	0.04	2.5e-04	8.5	8.3	1.3e-16	0.80	0.06	0.90	FALSE
12	GTEx	Colon Sigmoid	LINC00674	0.42	0.09	lasso	8	0.12	5.5e-05	8.7	8.1	4.4e-16	0.80	0.15	0.65	FALSE
15	GTEx	Esophagus Muscularis	LINC00674	0.11	0.04	lasso	6	0.07	7.9e-05	5.0	8.0	1.4e-15	0.77	0.18	0.79	FALSE
22	GTEx	Skin Sun Exposed Lower leg	BPTF	0.10	0.01	enet	14	0.03	2.7e-03	8.4	-7.7	1.3e-14	-0.69	0.05	0.79	FALSE
17	GTEx	Heart Atrial Appendage	LINC00674	0.14	0.08	lasso	17	0.09	1.1e-04	5.0	7.6	3.3e-14	0.73	0.05	0.87	FALSE
18	GTEx	Lung	LINC00674	0.14	0.03	enet	22	0.08	2.1e-06	9.7	7.6	3.3e-14	0.80	0.17	0.82	FALSE
23	GTEx	Spleen	C17orf58	0.30	-0.01	lasso	8	-0.01	4.6e-01	5.0	7.5	4.5e-14	0.81	0.03	0.34	FALSE
16	GTEx	Esophagus Muscularis	LRRC37A16P	0.12	0.03	enet	21	0.02	3.2e-02	9.7	6.8	1.3e-11	0.64	0.02	0.80	FALSE
24	GTEx	Stomach	RP11-147L13.8	0.23	-0.01	enet	9	0.01	8.1e-02	2.9	6.6	3.0e-11	0.57	0.04	0.19	FALSE
20	GTEx	Nerve Tibial	LINC00674	0.09	0.01	enet	13	0.03	2.2e-03	5.0	6.6	3.4e-11	0.65	0.20	0.23	FALSE
14	GTEx	Esophagus Mucosa	LRRC37A16P	0.11	0.06	enet	13	0.08	7.5e-06	6.6	-6.4	1.2e-10	-0.67	0.13	0.81	FALSE
6	GTEx	Artery Aorta	LINC00674	0.12	0.00	lasso	5	0.01	1.5e-01	5.0	6.3	3.4e-10	0.58	0.08	0.33	FALSE
19	GTEx	Muscle Skeletal	LRRC37A16P	0.14	0.04	lasso	5	0.08	3.3e-08	5.0	-6.2	7.3e-10	-0.59	0.99	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	LINC00674	0.29	0.03	enet	40	0.03	6.9e-03	8.7	6.2	7.6e-10	0.63	0.08	0.49	FALSE
26	GTEx	Thyroid	SH3GL1P3	0.08	0.00	lasso	3	0.00	2.8e-01	5.0	5.8	5.3e-09	0.56	0.05	0.45	FALSE
25	GTEx	Thyroid	LINC00674	0.09	0.10	enet	16	0.12	4.0e-09	5.0	5.8	6.6e-09	0.61	0.56	0.39	FALSE
2	GTEx	Adipose Subcutaneous	LRRC37A16P	0.10	0.10	enet	10	0.14	2.9e-11	8.5	5.8	6.8e-09	0.60	0.95	0.04	FALSE
13	GTEx	Colon Sigmoid	RP11-147L13.8	0.12	0.20	lasso	3	0.15	4.4e-06	5.0	5.4	5.7e-08	0.51	0.36	0.44	FALSE
4	GTEx	Adipose Subcutaneous	RP11-147L13.8	0.28	0.09	enet	27	0.23	9.7e-19	5.0	5.3	9.6e-08	0.46	1.00	0.00	FALSE
27	GTEx	Thyroid	RP11-147L13.8	0.23	0.17	lasso	3	0.16	3.5e-12	5.0	5.3	1.5e-07	0.49	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LOC651250	0.02	0.02	blup	2	0.03	1.9e-03	4.6	-5.2	2.2e-07	-0.51	0.00	0.07	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC651250	0.03	0.02	enet	2	0.02	2.0e-03	4.6	-5.2	2.4e-07	-0.55	0.00	0.12	FALSE