TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
←
→
chr8:22,428,708-24,094,711
Best TWAS P=5.37e-10 · Best GWAS P=1.92e-11 conditioned to 0.0662
22.4M
22.6M
22.8M
23M
23.2M
23.4M
23.6M
23.8M
24M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Thyroid Carcinoma
CHMP7
0.10
0.02
lasso
6
0.04
5.4e-05
3.1
-6.2
5.4e-10
0.74
0.00
0.99
TRUE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
STC1
0.04
0.05
enet
7
0.06
8.9e-12
-5.6
5.4
6.4e-08
-0.05
0.01
0.99
TRUE
1
GTEx
Cells Transformed fibroblasts
SLC25A37
0.13
0.05
lasso
5
0.04
3.0e-04
-5.3
5.3
1.0e-07
-0.12
0.62
0.16
TRUE
2
YFS
Blood
R3HCC1
0.03
0.01
lasso
6
0.01
5.3e-04
-5.9
5.7
1.6e-08
-0.73
0.03
0.96
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CHMP7
0.03
0.03
blup
89
0.01
3.8e-02
3.1
-5.3
8.9e-08
0.51
0.06
0.12
FALSE