[Hub]/) : Traits : Whole body fat-free mass :

chr1:25,488,741-27,488,299

Best TWAS P=8.22e-15 · Best GWAS P=7.91e-15 conditioned to 0.514

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts RP1-125I3.2 0.06 0.04 enet 19 0.03 3.3e-03 5.6 -6.4 1.6e-10 -0.50 0.09 0.38 FALSE
2 GTEx Esophagus Mucosa DHDDS 0.11 0.06 lasso 4 0.04 6.6e-04 -5.0 -5.4 7.3e-08 -0.20 0.57 0.02 FALSE
3 GTEx Esophagus Mucosa PDIK1L 0.10 0.09 lasso 6 0.09 8.8e-07 7.6 -7.4 9.9e-14 -0.95 0.02 0.98 FALSE
4 GTEx Nerve Tibial PDIK1L 0.09 0.01 enet 10 0.03 2.2e-03 5.7 -5.7 1.6e-08 -0.75 0.21 0.72 FALSE
5 GTEx Pancreas CNKSR1 0.20 0.03 enet 20 0.04 7.3e-03 5.7 -6.2 6.0e-10 -0.58 0.08 0.44 FALSE
6 GTEx Pituitary CNKSR1 0.38 0.16 lasso 7 0.15 1.4e-04 4.6 -5.8 8.9e-09 -0.71 0.07 0.79 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic CNKSR1 0.15 0.10 lasso 7 0.09 1.0e-05 4.6 -5.8 7.4e-09 -0.73 0.18 0.81 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic PDIK1L 0.22 0.05 enet 37 0.11 8.3e-07 7.6 -5.6 2.3e-08 -0.80 0.02 0.98 FALSE
9 GTEx Skin Sun Exposed Lower leg PDIK1L 0.14 0.05 enet 23 0.12 3.1e-10 7.6 -5.7 1.4e-08 -0.76 0.02 0.98 FALSE
10 GTEx Thyroid DHDDS 0.14 0.08 enet 22 0.07 5.8e-06 6.3 -6.1 1.1e-09 -0.14 0.66 0.04 TRUE
11 GTEx Thyroid CNKSR1 0.10 0.04 lasso 7 0.03 2.1e-03 6.1 -6.5 6.8e-11 -0.73 0.11 0.87 FALSE
12 GTEx Whole Blood CEP85 0.07 0.01 enet 17 0.02 1.3e-02 -2.5 -5.3 1.1e-07 -0.29 0.16 0.41 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM63 0.03 0.02 blup 33 0.02 4.6e-03 7.8 7.4 1.5e-13 0.91 0.01 0.90 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma PDIK1L 0.02 0.01 blup 37 0.02 6.1e-05 7.7 -5.8 6.5e-09 -0.87 0.02 0.94 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM63 0.15 0.16 lasso 2 0.16 2.3e-32 7.8 7.8 9.0e-15 0.97 0.00 1.00 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM63 0.14 0.15 lasso 1 0.14 2.2e-07 7.6 7.6 2.5e-14 0.95 0.01 0.99 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma TRIM63 0.08 0.10 lasso 4 0.10 3.7e-06 7.6 7.3 3.3e-13 0.95 0.01 0.99 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GRRP1 0.11 0.02 blup 52 0.03 8.8e-05 -3.0 5.7 1.5e-08 0.47 0.02 0.28 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDIK1L 0.02 0.02 blup 37 0.02 2.8e-03 7.7 -7.6 3.0e-14 -0.93 0.01 0.84 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC30A2 0.03 0.02 lasso 3 0.01 1.1e-02 4.8 -6.1 1.3e-09 -0.74 0.02 0.90 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM63 0.11 0.11 enet 4 0.12 9.0e-14 7.6 6.9 5.3e-12 0.95 0.00 1.00 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma PDIK1L 0.03 0.01 blup 37 0.02 2.6e-03 6.3 -7.7 1.8e-14 -0.85 0.01 0.57 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM63 0.29 0.33 enet 20 0.33 2.5e-38 7.6 7.8 8.2e-15 0.92 0.00 1.00 TRUE
24 The Cancer Genome Atlas Lung Adenocarcinoma TRIM63 0.14 0.20 enet 7 0.21 9.4e-24 7.5 7.2 8.6e-13 0.95 0.01 0.99 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CNKSR1 0.11 0.03 blup 57 0.05 3.5e-06 6.1 -5.4 8.4e-08 -0.65 0.14 0.55 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PDIK1L 0.02 0.00 blup 37 0.02 1.2e-03 3.6 -6.3 3.9e-10 -0.89 0.02 0.73 FALSE
27 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIM63 0.16 0.11 lasso 1 0.10 2.0e-11 7.6 7.6 2.7e-14 0.96 0.00 1.00 FALSE
28 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM63 0.14 0.18 lasso 7 0.15 3.0e-10 7.4 7.2 4.2e-13 0.95 0.02 0.98 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma SH3BGRL3 0.05 0.03 lasso 2 0.03 9.3e-04 5.6 6.2 7.4e-10 0.56 0.00 0.95 FALSE
30 The Cancer Genome Atlas Rectum Adenocarcinoma TRIM63 0.28 0.22 lasso 3 0.20 1.7e-05 4.8 6.0 1.5e-09 0.72 0.02 0.89 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma TRIM63 0.18 0.26 enet 7 0.26 3.0e-25 7.5 7.4 1.5e-13 0.94 0.01 0.99 FALSE
32 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TRIM63 0.19 0.07 blup 33 0.14 1.3e-04 7.6 6.7 1.6e-11 0.88 0.01 0.99 FALSE