[Hub]/) : Traits : Whole body fat-free mass : ← →

chr1:25,488,741-27,488,299

Best TWAS P=8.22e-15 · Best GWAS P=7.91e-15 conditioned to 0.514

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIM63	0.29	0.33	enet	20	0.33	2.5e-38	7.6	7.8	8.2e-15	0.92	0.00	1.00	TRUE
10	GTEx	Thyroid	DHDDS	0.14	0.08	enet	22	0.07	5.8e-06	6.3	-6.1	1.1e-09	-0.14	0.66	0.04	TRUE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM63	0.15	0.16	lasso	2	0.16	2.3e-32	7.8	7.8	9.0e-15	0.97	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	PDIK1L	0.03	0.01	blup	37	0.02	2.6e-03	6.3	-7.7	1.8e-14	-0.85	0.01	0.57	FALSE
16	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TRIM63	0.14	0.15	lasso	1	0.14	2.2e-07	7.6	7.6	2.5e-14	0.95	0.01	0.99	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TRIM63	0.16	0.11	lasso	1	0.10	2.0e-11	7.6	7.6	2.7e-14	0.96	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDIK1L	0.02	0.02	blup	37	0.02	2.8e-03	7.7	-7.6	3.0e-14	-0.93	0.01	0.84	FALSE
3	GTEx	Esophagus Mucosa	PDIK1L	0.10	0.09	lasso	6	0.09	8.8e-07	7.6	-7.4	9.9e-14	-0.95	0.02	0.98	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM63	0.03	0.02	blup	33	0.02	4.6e-03	7.8	7.4	1.5e-13	0.91	0.01	0.90	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM63	0.18	0.26	enet	7	0.26	3.0e-25	7.5	7.4	1.5e-13	0.94	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	TRIM63	0.08	0.10	lasso	4	0.10	3.7e-06	7.6	7.3	3.3e-13	0.95	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TRIM63	0.14	0.18	lasso	7	0.15	3.0e-10	7.4	7.2	4.2e-13	0.95	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	TRIM63	0.14	0.20	enet	7	0.21	9.4e-24	7.5	7.2	8.6e-13	0.95	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIM63	0.11	0.11	enet	4	0.12	9.0e-14	7.6	6.9	5.3e-12	0.95	0.00	1.00	FALSE
32	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	TRIM63	0.19	0.07	blup	33	0.14	1.3e-04	7.6	6.7	1.6e-11	0.88	0.01	0.99	FALSE
11	GTEx	Thyroid	CNKSR1	0.10	0.04	lasso	7	0.03	2.1e-03	6.1	-6.5	6.8e-11	-0.73	0.11	0.87	FALSE
1	GTEx	Cells Transformed fibroblasts	RP1-125I3.2	0.06	0.04	enet	19	0.03	3.3e-03	5.6	-6.4	1.6e-10	-0.50	0.09	0.38	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PDIK1L	0.02	0.00	blup	37	0.02	1.2e-03	3.6	-6.3	3.9e-10	-0.89	0.02	0.73	FALSE
5	GTEx	Pancreas	CNKSR1	0.20	0.03	enet	20	0.04	7.3e-03	5.7	-6.2	6.0e-10	-0.58	0.08	0.44	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	SH3BGRL3	0.05	0.03	lasso	2	0.03	9.3e-04	5.6	6.2	7.4e-10	0.56	0.00	0.95	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC30A2	0.03	0.02	lasso	3	0.01	1.1e-02	4.8	-6.1	1.3e-09	-0.74	0.02	0.90	FALSE
30	The Cancer Genome Atlas	Rectum Adenocarcinoma	TRIM63	0.28	0.22	lasso	3	0.20	1.7e-05	4.8	6.0	1.5e-09	0.72	0.02	0.89	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	PDIK1L	0.02	0.01	blup	37	0.02	6.1e-05	7.7	-5.8	6.5e-09	-0.87	0.02	0.94	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	CNKSR1	0.15	0.10	lasso	7	0.09	1.0e-05	4.6	-5.8	7.4e-09	-0.73	0.18	0.81	FALSE
6	GTEx	Pituitary	CNKSR1	0.38	0.16	lasso	7	0.15	1.4e-04	4.6	-5.8	8.9e-09	-0.71	0.07	0.79	FALSE
9	GTEx	Skin Sun Exposed Lower leg	PDIK1L	0.14	0.05	enet	23	0.12	3.1e-10	7.6	-5.7	1.4e-08	-0.76	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GRRP1	0.11	0.02	blup	52	0.03	8.8e-05	-3.0	5.7	1.5e-08	0.47	0.02	0.28	FALSE
4	GTEx	Nerve Tibial	PDIK1L	0.09	0.01	enet	10	0.03	2.2e-03	5.7	-5.7	1.6e-08	-0.75	0.21	0.72	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	PDIK1L	0.22	0.05	enet	37	0.11	8.3e-07	7.6	-5.6	2.3e-08	-0.80	0.02	0.98	FALSE
2	GTEx	Esophagus Mucosa	DHDDS	0.11	0.06	lasso	4	0.04	6.6e-04	-5.0	-5.4	7.3e-08	-0.20	0.57	0.02	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CNKSR1	0.11	0.03	blup	57	0.05	3.5e-06	6.1	-5.4	8.4e-08	-0.65	0.14	0.55	FALSE
12	GTEx	Whole Blood	CEP85	0.07	0.01	enet	17	0.02	1.3e-02	-2.5	-5.3	1.1e-07	-0.29	0.16	0.41	FALSE