TWAS hub - SLC30A2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0252	0.0118	3.3e-07	0.041	0.030	0.032	NA	0.035	6.7e-09	7.6e-07	2.9e-07	NA	7.1e-08
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0307	0.0179	1.7e-03	0.019	0.012	0.011	NA	0.013	3.0e-03	1.3e-02	1.8e-02	NA	1.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Chronic bronchitis/emphysema (mother)	12.3	14.3	18.2	3.2	4.3
Type 2 Diabetes (T2D) (2018)	9.5	17.8	18.3	4.3	4.2
Maternal smoking around birth	9.1	13.1	17.5	3.0	4.2
Supplements: Vitamin C	8.9	10.6	10.8	-3.2	-3.3
Forced expiratory volume in 1-second (FEV1), Best measure	8.3	26.4	40.4	-3.5	-6.4
Mineral and other dietary supplements	7.9	10.7	11.4	3.4	3.2
Forced vital capacity (FVC), Best measure	7.5	27.5	41.7	-3.6	-6.5
Vitamin and mineral supplements	7.4	10.0	12.3	3.5	2.8
Forced expiratory volume in 1-second (FEV1)	7.3	24.7	39.3	-3.2	-6.3
Pulse rate, automated reading	7.0	22.8	31.5	3.8	5.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	7.0	8.2	9.7	3.1	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	6.9	14.6	21.7	-2.7	-4.7
Diabetes diagnosed by doctor	6.6	10.8	11.4	3.4	3.2
Alcohol usually taken with meals	6.4	10.4	11.5	-3.4	-3.0
Eye problems/disorders: Diabetes related eye disease	5.9	6.4	7.5	2.7	2.3
Diabetes (mother)	5.9	7.5	7.8	2.8	2.7
Supplements: Fish oil (including cod liver oil)	5.9	7.7	8.4	-2.7	-2.9
Bipolar Disorder (2018)	5.6	8.9	10.5	2.7	3.2
Average weekly beer plus cider intake	5.6	8.1	9.4	3.1	2.6
Medication: Metformin	5.5	7.7	9.1	2.5	3.0
Sitting height	5.5	39.0	53.0	-5.0	-7.3
Peak expiratory flow (PEF)	5.1	11.8	18.6	-2.2	-4.3
Forced vital capacity (FVC)	5.0	19.4	32.3	-2.5	-5.7
High cholesterol (Self-reported)	5.0	8.9	9.4	3.1	2.9
Fed-up feelings	4.9	8.9	13.5	2.1	3.7
Trunk fat-free mass	4.7	27.2	43.8	-3.2	-6.6
Trunk predicted mass	4.7	26.7	43.2	-3.2	-6.6
Medication: Gliclazide	4.7	5.3	5.7	2.4	2.2
Diabetes (self-reported)	4.4	6.7	8.0	2.8	2.3
Comparative height size at age 10	4.4	24.3	36.7	-3.5	-6.1
Mother’s age at death	4.4	5.5	7.3	-1.9	-2.7
Hand grip strength (left)	4.2	11.1	11.2	-3.3	-3.3
Bipolar Disorder (2011)	4.1	4.0	5.4	1.6	2.3
Multivitamins +/- minerals	4.1	5.2	7.5	-2.7	-1.7
Supplements: Glucosamine	4.1	5.3	5.4	-2.3	-2.3
Schizophrenia vs Biploar Disorder	4.0	5.2	5.8	-2.4	-2.2
Arm fat-free mass (right)	4.0	20.5	34.2	-2.6	-5.8
Whole body water mass	4.0	23.1	37.9	-2.9	-6.2
Whole body fat-free mass	3.9	22.4	36.8	-2.8	-6.1
Number of live births	3.8	5.4	7.2	1.9	2.7
Pulse rate	3.8	6.4	10.3	1.6	3.2
Worry too long after embarrassment	3.7	6.3	8.1	-2.8	-2.1
Arm predicted mass (right)	3.7	18.9	32.3	-2.4	-5.7
Height	3.6	69.1	108.2	-5.5	-10.4
Townsend deprivation index at recruitment	3.6	5.1	7.2	2.7	1.7
Standing height	3.6	35.2	53.0	-4.2	-7.3
Ever taken oral contraceptive pill	3.6	4.0	4.1	2.0	2.0
Arm fat-free mass (left)	3.6	18.2	30.7	-2.4	-5.5
Illnesses of mother	3.5	4.3	6.8	-1.4	-2.6
Tinnitus: Yes, now most or all of the time	3.4	3.9	4.1	-2.0	-1.9
Worrier / anxious feelings	3.3	6.2	11.8	-3.4	-0.8
Illness, injury, bereavement, stress in last 2 years	3.3	4.1	4.4	2.1	1.9
Basal metabolic rate	3.3	18.5	30.8	-2.5	-5.5
Lung FVC	3.2	16.5	26.0	-2.6	-5.1
High blood pressure (siblings)	3.2	4.6	5.1	-2.3	-2.0
Qualifications: College or University degree	3.2	10.1	14.6	-2.4	-3.8
Depressed Affect (Nagel 2018)	3.0	6.3	8.6	2.0	2.9
HbA1C	2.9	3.3	4.3	2.1	1.5
Hand grip strength (right)	2.9	8.0	12.2	-1.9	-3.5
Leg fat-free mass (right)	2.9	15.5	25.9	-2.3	-5.1
Leg predicted mass (right)	2.9	15.2	25.7	-2.2	-5.1
Leg fat-free mass (left)	2.8	14.9	25.2	-2.1	-5.0
Leg predicted mass (left)	2.8	15.0	25.3	-2.2	-5.0
Arm predicted mass (left)	2.8	14.2	24.6	-2.0	-5.0
Body Mass Index (BMI) (2010)	2.7	3.7	4.5	-1.7	-2.1
Medication: Seretide 50 evohaler	2.7	3.1	3.7	-1.6	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	6.0	-2.5	-2.3
Eye problems/disorders: Cataract	2.6	3.0	4.8	2.2	1.1
Irritability	2.6	4.3	7.7	1.0	2.8
Bipolar Disorder or Schizophrenia	2.5	6.2	6.4	2.4	2.5
Ever had prostate specific antigen (PSA) test	2.5	2.9	3.9	-1.4	-2.0
Cholesterol lowering medication	2.5	3.7	4.2	2.0	1.8
Waist Hip Ratio (WHR)	2.4	11.0	11.7	3.2	3.4
Ever had hysterectomy (womb removed)	2.4	2.7	4.0	2.0	1.2
Family relationship satisfaction	2.4	2.9	4.7	1.1	2.2
Miserableness	2.4	4.1	4.2	2.0	2.1
Mean Putamen Volume	2.3	2.6	3.6	-1.9	-1.3
Birth weight	2.2	4.8	6.6	-1.7	-2.6
Medication: Atorvastatin	2.1	2.7	4.1	1.1	2.0
Worry (Nagel 2018)	2.0	4.1	8.3	-2.9	0.1
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	2.9	-1.7	-1.5
Heart attack	2.0	2.6	4.0	2.0	1.1
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.3	4.9	1.3	2.2
Mouth/teeth dental problems: Dentures	2.0	3.3	4.9	2.2	1.3
Gout (self-reported)	2.0	2.7	3.8	2.0	1.2
Medication: Omeprazole	2.0	2.4	4.0	0.8	2.0
Heart attack/myocardial infarction (self-reported)	2.0	2.6	3.9	2.0	1.1
Coronary Artery Disease (CAD)	1.9	2.3	3.0	1.2	1.7
Blood Eosinophil Count	1.9	14.6	21.0	2.9	4.6
Diabetes (father)	1.9	2.4	4.1	0.8	2.0
Illnesses of siblings	1.9	2.7	3.3	1.8	1.4
Number of full brothers	1.9	2.4	3.5	1.1	1.9
Medication: Allopurinol	1.9	2.6	4.4	2.1	0.9
Average weekly fortified wine intake	1.8	2.1	3.6	-0.7	-1.9
Medication: Ramipril	1.8	2.3	3.1	1.8	1.2
Hair/balding pattern: Pattern 4	1.8	4.3	4.4	2.1	2.0
Handedness (chirality/laterality): Left-handed	1.8	2.2	3.5	-1.9	-1.0
Past tobacco smoking	1.7	3.1	4.0	-1.4	-2.0
Nervous feelings	1.7	3.2	6.3	-2.5	0.1
Hypothyroidism (self reported)	1.6	3.6	5.4	2.3	1.3
Exposure to tobacco smoke at home	1.6	1.8	1.9	1.4	1.3
Hearing aid user	1.6	1.8	2.6	1.6	1.0
Frequency of depressed mood in last 2 weeks	1.5	2.1	2.5	1.3	1.6
Serious illness, injury or assault to yourself	1.5	1.9	2.2	-1.5	-1.2
Birth weight of first child	1.5	2.7	4.7	-0.9	-2.2
Ever highly irritable/argumentative for 2 days	1.5	1.8	2.8	1.7	0.9
Heart disease (mother)	1.5	1.8	3.2	0.6	1.8
Qualifications: nursing, teaching	1.5	2.3	4.4	-0.4	-2.1
Alcohol drinker status: Previous	1.5	1.7	2.8	1.7	0.7
Ulcerative Colitis	1.4	2.1	3.6	1.9	0.8
Lung FEV1/FVC ratio	1.4	7.1	7.3	-2.6	-2.7
Ever used hormone-replacement therapy (HRT)	1.4	1.8	2.6	1.6	1.0
Current tobacco smoking	1.4	2.3	3.7	1.0	1.9
Weight	1.4	6.9	11.9	-1.4	-3.4
Prospective memory result	1.4	1.7	2.2	-1.5	-1.1
Loud music exposure frequency	1.4	1.5	3.0	1.7	0.3
Smoking status: Previous	1.4	2.1	2.3	1.4	1.5
Myopia	1.4	2.1	3.0	-1.7	-1.0
Smoking Status	1.3	3.1	4.8	1.2	2.2
Intelligence (Savage-Jansen 2018)	1.2	3.7	4.2	2.1	1.8
Crohns Disease (2017)	1.2	2.5	3.1	-1.8	-1.4
Number of treatments/medications taken	1.2	2.1	2.1	-1.4	-1.5
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.0	1.4	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.7	-1.6	-0.3
Illnesses of siblings: Diabetes	1.2	1.4	2.1	1.4	0.9
Commuting to job workplace: Walk	1.2	1.3	2.2	-0.7	-1.5
Ovarian Cancer	1.1	1.5	2.8	1.7	0.4
HDL Cholesterol	1.1	1.9	3.1	-1.8	-0.8
LDL Cholesterol	1.1	1.7	2.6	0.9	1.6
Primary Biliary Cirrhosis	1.1	1.6	2.3	0.9	1.5
Type 2 Diabetes (T2D) (2012)	1.1	1.3	2.0	1.4	0.7
Angina	1.1	1.5	1.7	1.1	1.3
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.6	2.1	1.5	1.1
Impedance of arm (right)	1.1	5.0	7.8	1.5	2.8
Angina (self-reported)	1.1	1.5	2.2	0.9	1.5
Suffer from ‘nerves’	1.1	1.8	3.5	0.2	1.9
Unable to work because of sickness or disability	1.1	1.4	2.2	0.7	1.5
Basal cell carcinoma (self-reported)	1.1	1.3	2.4	0.5	1.5
Impedance of whole body	1.1	5.4	8.8	1.4	3.0
Systolic blood pressure, automated reading	1.0	3.0	3.5	-1.9	-1.6
Impedance of leg (right)	1.0	4.8	8.0	1.3	2.8
Impedance of leg (left)	1.0	5.0	8.5	1.2	2.9
Hearing difficulty/problems with background noise	1.0	1.5	2.8	0.5	1.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	1.8	0.9	1.3
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	3.2	1.8	0.9
Eye problems/disorders: None of the above	1.0	1.1	1.8	-1.3	-0.7
Emphysema/chronic bronchitis	1.0	1.1	1.8	0.6	1.4
Friendships satisfaction	1.0	1.2	2.4	1.5	0.3
Smoking status: Current	1.0	1.6	2.8	0.6	1.7
Qualifications: CSEs or equivalent	0.9	1.2	2.0	0.6	1.4
Fluid intelligence score	0.9	1.9	2.2	1.5	1.3
Exposure to tobacco smoke outside home	0.9	1.1	1.6	0.8	1.3
Medication: Aspirin	0.9	1.1	1.8	1.3	0.7
Guilty feelings	0.9	1.4	2.4	-1.6	-0.6
Ever depressed for a whole week	0.9	1.2	2.1	1.4	0.5
Reaction Time	0.8	1.5	2.9	0.0	-1.7
Triglycerides	0.8	1.4	2.0	1.4	0.9
Pack years adult smoking proportion	0.8	1.2	1.5	1.0	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	1.8	-1.4	-1.3
Time employed in main current job	0.8	0.9	1.2	0.8	1.1
Qualifications: A levels/AS levels or equivalent	0.8	1.8	3.0	-0.8	-1.7
Blood clot in the leg (DVT)	0.8	1.1	1.6	-0.8	-1.3
Age at first live birth	0.8	1.5	2.1	-1.0	-1.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.5	1.2	0.2
Mouth/teeth dental problems	0.7	1.1	1.1	-1.0	-1.1
Neuroticism score	0.7	1.4	2.5	-0.6	1.6
Hip circumference	0.7	2.9	5.2	-0.7	-2.3
Father’s age at death	0.7	1.0	1.3	-0.8	-1.2
Impedance of arm (left)	0.7	3.3	5.5	1.1	2.3
Breastfed as a baby	0.7	0.9	1.0	-1.0	-0.9
Pulse wave reflection index	0.7	0.9	0.9	1.0	0.9
Pulse wave peak to peak time	0.7	0.8	0.9	-0.9	-0.9
Medication: Aspirin	0.7	0.9	1.6	1.3	0.5
Loneliness, isolation	0.7	1.0	1.1	1.1	0.9
Fractured/broken bones in last 5 years	0.7	1.0	1.7	1.3	0.5
Age started oral contraceptive pill	0.7	0.9	1.2	-0.7	-1.1
Age at First Birth	0.6	0.9	1.2	-0.7	-1.1
Heel T-Score	0.6	4.7	8.2	-2.9	-1.1
Neuroticism	0.6	1.4	2.3	-1.5	0.7
Medication: Co-codamol	0.6	0.7	0.7	-0.8	-0.8
Medication: Atenolol	0.6	0.7	1.3	1.1	0.4
Chronic bronchitis/emphysema (father)	0.6	0.7	1.3	0.2	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.3	-0.5	-1.2
Depression (self-reported)	0.6	0.7	1.2	-0.4	1.1
Tense / ‘highly strung’	0.6	1.0	2.1	-0.0	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.4	-1.2	-0.6
Mean time to correctly identify matches	0.6	1.1	2.2	-0.1	-1.5
Mood swings	0.6	1.2	2.2	0.3	1.5
Long-standing illness, disability or infirmity	0.6	0.9	1.7	0.3	1.3
Back pain experienced in last month	0.6	0.9	1.0	1.0	0.9
Risk taking	0.6	0.9	1.7	-0.2	-1.3
Pack years of smoking	0.6	0.9	1.1	0.8	1.0
Prostate Cancer	0.5	0.7	0.9	-0.7	0.9
Severe depression (siblings)	0.5	0.6	1.1	1.0	0.3
Age when periods started (menarche)	0.5	1.2	1.3	-1.1	-1.1
Number of incorrect matches in round	0.5	0.8	1.2	-0.6	-1.1
Hair/balding pattern: Pattern 2	0.5	0.6	0.9	0.5	1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	1.5	0.5	-1.2
Medication: Paracetamol	0.5	0.8	1.6	-1.2	0.3
Comparative body size at age 10	0.5	1.5	1.8	-1.1	-1.4
Medication: Ibuprofen	0.5	0.5	0.9	-0.4	-1.0
Number of full sisters	0.5	0.6	0.8	0.9	0.7
Overall health rating	0.5	1.1	1.9	0.5	1.4
Had major operations	0.5	0.6	0.6	0.7	0.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.2	0.1	1.1
Breast cancer (self-reported)	0.5	0.6	1.2	-1.1	-0.2
Illnesses of father: None of the above (group 1)	0.5	0.6	0.6	0.8	-0.8
Wears glasses or contact lenses	0.5	0.6	0.6	-0.8	-0.8
Financial situation satisfaction	0.5	0.7	0.9	1.0	0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.9	-0.6	-1.0
Medication: Paracetamol	0.5	0.7	1.4	-1.2	-0.1
Supplements: Calcium	0.5	0.6	0.8	-0.6	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	0.9	-0.5	-1.0
Neuroticism (Nagel 2018)	0.4	0.9	1.1	-1.1	0.9
Major Depression (MDD)	0.4	0.5	0.9	1.0	0.1
Verbal and Numeric Reasoning (VNR)	0.4	0.8	1.0	0.8	1.0
Breast Cancer	0.4	1.0	2.0	1.4	0.1
Chronotype (morning person)	0.4	0.8	1.4	-1.2	0.5
Taking other prescription medications	0.4	0.7	0.8	-0.9	-0.8
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.7	-0.8	-0.4
High blood pressure (mother)	0.4	0.5	0.6	-0.8	-0.6
Trunk fat mass	0.4	1.6	3.0	-0.3	-1.7
Had menopause	0.4	0.5	1.0	1.0	0.2
Alcohol intake versus 10 years previously	0.4	0.6	0.7	0.7	-0.9
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.0	1.0	0.1
Number of children fathered	0.4	0.4	0.7	-0.4	-0.8
Medication: Blood pressure	0.4	0.6	1.2	1.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.9	-0.2	-1.0
Ever had bowel cancer screening	0.4	0.4	0.7	0.4	-0.9
Asthma (self-reported)	0.4	0.9	1.7	-0.0	-1.3
Osteoarthritis (self-reported)	0.4	0.5	0.6	0.7	0.8
Average weekly champagne plus white wine intake	0.4	0.6	0.6	0.8	0.7
Eye problems/disorders: Glaucoma	0.4	0.5	0.8	0.4	0.9
Leg fat percentage (left)	0.4	1.5	1.6	1.2	1.3
Pain experienced in last month	0.4	0.7	1.3	1.1	-0.1
Depression (Nagel 2018)	0.3	0.5	0.9	0.3	0.9
Schizophrenia (2018)	0.3	0.7	0.9	1.0	0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	0.4	0.7	0.6
Irritable Bowel Disease (IBD)	0.3	0.8	1.3	-0.4	-1.2
Rheumatoid Arthritis	0.3	0.4	0.4	0.7	0.6
Blood Red Count	0.3	2.7	4.4	2.1	1.0
Respiratory disease	0.3	0.7	1.0	0.6	-1.0
Hearing difficulty/problems: Yes	0.3	0.4	0.8	0.3	0.9
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	0.3	0.9
Medication: Levothyroxine sodium	0.3	0.5	0.7	0.8	0.5
Had other major operations	0.3	0.4	0.5	0.4	0.7
Qualifications: None of the above	0.3	0.7	1.3	0.3	1.2
Pain all over the body in last month	0.3	0.3	0.3	-0.6	0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.6	-0.8	-0.6
Medication: Cholesterol lowering	0.3	0.4	0.6	0.8	0.4
Medication: Lansoprazole	0.3	0.3	0.6	0.1	-0.8
Leg fat percentage (right)	0.3	1.3	1.3	1.1	1.1
Wheeze or whistling in the chest in last year	0.3	0.6	0.6	0.7	0.8
Alcohol intake frequency.	0.3	0.6	1.2	0.3	-1.1
Chest pain or discomfort	0.3	0.5	0.5	0.7	0.6
Leg pain on walking	0.3	0.4	0.7	-0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.7	-0.3	-0.8
Commuting to job workplace: Public transport	0.3	0.4	0.4	-0.6	-0.6
Diastolic blood pressure, automated reading	0.3	0.8	1.2	0.6	1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.7	-0.0	0.9
Crohns Disease (2012)	0.2	0.2	0.3	-0.6	-0.4
Schizophrenia (2014)	0.2	0.4	0.8	-0.9	-0.2
Blood Platelet Count	0.2	2.6	3.5	1.9	1.3
Blood White Count	0.2	1.5	2.3	-1.5	-0.8
BMI	0.2	0.9	1.7	-0.0	-1.3
Average weekly spirits intake	0.2	0.2	0.3	0.6	0.3
Sensitivity / hurt feelings	0.2	0.4	0.8	0.2	0.9
Medication for hormone replacement therapy	0.2	0.2	0.4	-0.6	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	0.2	0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	-0.1	0.9
Stomach or abdominal pain in last month	0.2	0.3	0.3	-0.5	-0.6
Arm fat percentage (right)	0.2	0.7	1.0	1.0	0.7
Noisy workplace	0.2	0.2	0.4	0.7	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.5	-0.0	0.7
Asthma	0.2	0.3	0.6	0.2	-0.7
Lung cancer (father)	0.2	0.2	0.3	0.3	0.5
Pulse wave Arterial Stiffness index	0.2	0.3	0.3	0.6	0.4
Arm fat mass (right)	0.2	1.0	1.9	-0.2	-1.4
Length of working week for main job	0.2	0.2	0.3	-0.3	-0.6
Whole body fat mass	0.2	0.7	1.5	0.0	-1.2
Age at last live birth	0.2	0.3	0.3	-0.5	-0.6
Knee pain experienced in last month	0.2	0.2	0.5	-0.1	0.7
Illnesses of father: Heart disease	0.2	0.2	0.4	-0.6	0.3
Arm fat percentage (left)	0.2	0.6	0.9	1.0	0.6
Average weekly red wine intake	0.2	0.2	0.4	-0.4	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.3	0.3	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.6	-0.8	0.1
Arm fat mass (left)	0.2	0.8	1.7	-0.0	-1.3
Medication: Bendroflumethiazide	0.2	0.3	0.6	0.8	0.2
Medication: Lisinopril	0.2	0.3	0.5	0.1	-0.7
Illnesses of father: High blood pressure	0.2	0.2	0.4	-0.6	0.0
Alzheimer’s Disease (in mother)	0.1	0.2	0.3	-0.6	0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.1	-0.1	-0.4
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.6	-0.4
Neuroticism (2016)	0.1	0.1	0.2	0.5	-0.3
Systolic Blood Pressure	0.1	0.5	1.0	-1.0	-0.2
Allergy or Eczema	0.1	0.3	0.5	-0.7	0.0
Hair Pigment	0.1	3.4	3.6	1.8	1.9
Tanning	0.1	1.6	2.2	1.5	0.9
Relative age of first facial hair	0.1	0.2	0.3	-0.3	0.5
Trunk fat percentage	0.1	0.2	0.4	0.6	-0.1
Relative age voice broke	0.1	0.2	0.4	-0.0	0.6
Waist circumference	0.1	0.4	0.8	0.9	0.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.1	0.4
Medication: Simvastatin	0.1	0.2	0.3	0.5	0.4
Falls in the last year	0.1	0.1	0.1	0.4	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	-0.3	-0.2
Headache pain in last month	0.1	0.2	0.3	-0.6	0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.3	-0.5	0.2
Glaucoma (self-reported)	0.1	0.2	0.2	-0.3	0.5
Medication: Amlodipine	0.1	0.1	0.3	-0.1	-0.5
Body fat percentage	0.1	0.6	0.9	1.0	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.2	0.5
Neck or shoulder pain in last month	0.1	0.1	0.2	0.4	0.1
Migraine (self-reported)	0.1	0.1	0.1	0.2	0.4
Leg fat mass (right)	0.1	0.3	0.5	0.4	-0.7
Hypertension (Self-reported)	0.1	0.2	0.3	-0.3	-0.5
Osteoporosis (self-reported)	0.1	0.2	0.2	-0.4	0.4
Ever smoked	0.1	0.2	0.3	0.4	0.6
Heart disease (siblings)	0.1	0.1	0.2	-0.5	-0.1
Leg fat mass (left)	0.1	0.2	0.3	0.4	-0.5
Fasting Glucose	0.0	0.0	0.0	-0.1	-0.2
Lupus	0.0	0.0	0.0	-0.1	0.2
Cardiovascular Disease	0.0	0.1	0.2	0.4	-0.0
Supplements: Zinc	0.0	0.0	0.1	-0.1	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.4	-0.3
High blood pressure	0.0	0.0	0.0	-0.1	-0.2
Body mass index (BMI)	0.0	0.2	0.3	0.6	-0.3
Financial difficulties in last 2 years	0.0	0.1	0.1	0.3	-0.1
Allergy	0.0	0.0	0.0	-0.0	-0.0
Happiness	0.0	0.0	0.0	0.1	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	0.1	-0.0
Health satisfaction	0.0	0.0	0.0	-0.2	-0.0
Shortness of breath walking on level ground	0.0	0.0	0.0	0.1	0.1
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	-0.1	-0.2
Medication for cholesterol	0.0	0.0	0.0	0.2	0.2
Number of self-reported non-cancer illnesses	0.0	0.0	0.1	0.2	0.1
Medication: Blood pressure	0.0	0.1	0.1	-0.1	-0.3
Alcohol drinker status: Never	0.0	0.0	0.1	-0.0	-0.3
Number of operations (self-reported)	0.0	0.0	0.0	-0.0	-0.0
Commuting to job workplace: Cycle	0.0	0.0	0.0	0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

SLC30A2

Models

Trait associations