[Hub]/) : Traits : Whole body water mass :

chr7:90,624,416-93,160,671

Best TWAS P=6.04e-64 · Best GWAS P=5.36e-58 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDK6 0.12 0.10 lasso 2 0.10 1.9e-12 15.86 15.9 1.1e-56 1.00 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex KRIT1 0.04 0.01 blup 318 0.02 1.2e-03 4.44 -5.8 6.1e-09 -0.23 0.60 0.02 FALSE
3 GTEx Adipose Subcutaneous GATAD1 0.21 0.14 enet 10 0.16 3.4e-13 7.91 -5.8 6.6e-09 -0.37 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum GATAD1 0.12 0.08 lasso 5 0.06 7.5e-04 7.91 -7.9 2.2e-15 -0.46 0.81 0.06 FALSE
5 GTEx Adrenal Gland GATAD1 0.40 0.22 lasso 7 0.25 2.0e-09 7.91 -9.0 3.2e-19 -0.47 0.67 0.09 FALSE
6 GTEx Artery Aorta KRIT1 0.15 0.00 enet 24 0.03 1.3e-02 0.47 -7.4 1.9e-13 -0.28 0.12 0.05 FALSE
7 GTEx Artery Aorta GATAD1 0.09 0.08 enet 4 0.07 7.4e-05 7.91 -8.0 1.9e-15 -0.42 0.52 0.05 FALSE
8 GTEx Artery Coronary GATAD1 0.12 0.15 lasso 3 0.12 8.0e-05 7.88 -8.2 2.4e-16 -0.41 0.18 0.22 FALSE
9 GTEx Artery Tibial GATAD1 0.14 0.04 enet 17 0.04 4.1e-04 7.91 -7.7 1.8e-14 -0.38 0.70 0.11 FALSE
10 GTEx Artery Tibial AC000120.7 0.08 0.06 lasso 4 0.06 3.2e-05 4.32 -5.5 3.1e-08 -0.26 0.96 0.00 FALSE
11 GTEx Artery Tibial AC007566.10 0.13 0.04 lasso 5 0.00 3.1e-01 5.55 -6.5 8.0e-11 -0.15 0.08 0.04 FALSE
12 GTEx Brain Caudate basal ganglia GATAD1 0.21 0.09 lasso 4 0.08 2.3e-03 6.33 -9.1 8.2e-20 -0.43 0.07 0.31 FALSE
13 GTEx Brain Cortex AC000120.7 0.12 0.08 enet 16 0.07 7.0e-03 4.32 -5.9 4.3e-09 -0.42 0.14 0.05 FALSE
14 GTEx Breast Mammary Tissue (Female) AC007566.10 0.04 -0.01 lasso 2 0.01 2.0e-01 1.24 -7.6 2.2e-14 -0.37 0.02 0.22 FALSE
15 GTEx Cells Transformed fibroblasts GATAD1 0.23 0.20 lasso 4 0.22 1.4e-16 7.91 -10.5 5.7e-26 -0.58 0.97 0.03 FALSE
16 GTEx Colon Transverse GATAD1 0.13 0.00 enet 16 0.05 3.0e-03 7.91 -9.0 3.3e-19 -0.38 0.20 0.17 FALSE
17 GTEx Esophagus Mucosa GATAD1 0.16 0.05 enet 16 0.08 7.3e-06 7.91 -8.4 3.9e-17 -0.42 0.78 0.10 TRUE
18 GTEx Esophagus Muscularis GATAD1 0.18 0.10 enet 33 0.13 1.6e-08 7.91 -6.7 3.0e-11 -0.32 0.97 0.00 TRUE
19 GTEx Esophagus Muscularis FAM133B 0.07 0.01 enet 2 0.01 1.2e-01 -11.01 -11.0 2.9e-28 -0.46 0.06 0.41 FALSE
20 GTEx Lung GATAD1 0.15 0.12 lasso 2 0.11 1.1e-08 7.91 -7.9 3.1e-15 -0.42 0.99 0.00 FALSE
21 GTEx Muscle Skeletal PEX1 0.06 0.03 lasso 5 0.02 2.7e-03 6.63 7.1 9.4e-13 0.30 0.51 0.18 FALSE
22 GTEx Muscle Skeletal GATAD1 0.05 0.00 enet 13 0.01 2.4e-02 3.58 -7.8 7.4e-15 -0.38 0.47 0.04 FALSE
23 GTEx Nerve Tibial GATAD1 0.30 0.19 lasso 5 0.23 1.8e-16 7.91 -6.0 1.6e-09 -0.35 1.00 0.00 FALSE
24 GTEx Pancreas GATAD1 0.12 0.13 lasso 2 0.14 2.0e-06 7.91 -7.1 1.1e-12 -0.40 0.15 0.54 FALSE
25 GTEx Pituitary KRIT1 0.21 -0.01 enet 14 0.20 1.1e-05 0.20 -5.8 4.9e-09 -0.09 0.28 0.07 TRUE
26 GTEx Skin Not Sun Exposed Suprapubic GATAD1 0.22 0.27 lasso 4 0.26 1.1e-14 7.91 -8.1 5.8e-16 -0.42 1.00 0.00 FALSE
27 GTEx Skin Sun Exposed Lower leg PEX1 0.18 0.06 enet 41 0.03 1.5e-03 -8.84 -8.8 1.4e-18 -0.39 0.20 0.17 FALSE
28 GTEx Skin Sun Exposed Lower leg GATAD1 0.30 0.10 enet 14 0.16 7.0e-13 7.91 -7.8 6.0e-15 -0.39 1.00 0.00 FALSE
29 GTEx Spleen PEX1 0.18 0.00 enet 38 0.05 2.4e-02 4.34 -7.9 2.2e-15 -0.32 0.08 0.08 FALSE
30 GTEx Stomach GATAD1 0.30 0.13 lasso 5 0.15 8.6e-08 7.91 -8.0 8.9e-16 -0.46 0.98 0.00 FALSE
31 GTEx Testis CDK6 0.10 0.10 lasso 3 0.09 8.0e-05 16.04 -16.9 6.0e-64 -0.92 0.01 0.98 TRUE
32 GTEx Thyroid GATAD1 0.18 0.06 lasso 4 0.06 3.3e-05 7.91 -7.7 1.3e-14 -0.43 0.94 0.03 FALSE
33 METSIM Adipose GATAD1 0.10 0.05 lasso 7 0.06 9.4e-10 3.58 -6.1 1.3e-09 -0.40 1.00 0.00 FALSE
34 ROSMAP Brain Pre-frontal Cortex KRIT1 0.04 0.03 bslmm 311 0.01 9.0e-03 4.35 8.0 9.4e-16 0.49 0.74 0.05 TRUE
35 ROSMAP Brain Pre-frontal Cortex MTERF 0.04 0.00 blup 375 0.02 7.5e-04 2.45 5.3 9.1e-08 0.21 0.08 0.24 TRUE
36 ROSMAP Brain Pre-frontal Cortex GATAD1 0.17 0.15 lasso 4 0.16 6.0e-20 7.93 -8.0 8.8e-16 -0.43 1.00 0.00 FALSE
37 YFS Blood CYP51A1 0.03 0.06 blup 288 0.05 1.2e-16 4.45 -6.1 1.1e-09 -0.31 1.00 0.00 FALSE
38 YFS Blood GATAD1 0.01 0.01 blup 297 0.01 5.1e-04 7.91 -10.3 1.1e-24 -0.55 0.73 0.10 FALSE
39 The Cancer Genome Atlas Breast Invasive Carcinoma GATAD1 0.06 0.04 lasso 6 0.04 2.2e-09 7.67 -7.2 6.0e-13 -0.31 0.84 0.16 FALSE
40 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GATAD1 0.04 0.04 lasso 2 0.03 2.8e-04 7.67 -7.4 1.4e-13 -0.36 0.16 0.08 FALSE
41 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C7orf64 0.06 0.02 blup 36 0.02 6.0e-02 6.76 5.9 3.0e-09 0.22 0.04 0.05 FALSE