TWAS hub - MTERF

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.0425	0.0198	0.00130	-0.002	0.022	0.016	0.02	0.003	0.64000	0.00075	0.00290	0.0013	0.12000
2	TCGA	Prostate Adenocarcinoma	0.0296	0.0189	0.00035	0.030	0.035	0.033	NA	0.030	0.00041	0.00012	0.00021	NA	0.00037

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Risk taking	12.5	18.3	19.6	-4.4	-4.1
Medication: Lansoprazole	10.5	12.0	16.4	-2.8	-4.0
Breast Cancer	7.0	17.0	26.5	-2.7	-5.2
Bilateral oophorectomy (both ovaries removed)	7.0	8.1	13.9	-1.5	-3.7
Ever taken oral contraceptive pill	6.9	7.6	10.7	-2.1	-3.3
Systolic blood pressure, automated reading	6.6	19.3	23.6	-3.9	-4.9
Serious illness, injury or assault to yourself	6.6	8.1	8.4	-2.8	-2.9
Ever used hormone-replacement therapy (HRT)	6.0	7.6	10.0	-2.3	-3.2
Wears glasses or contact lenses	5.4	6.2	7.6	2.8	2.2
Pain type(s) experienced in last month: Hip pain	5.2	6.6	9.4	-2.0	-3.1
Number of operations (self-reported)	5.2	7.7	13.3	-1.5	-3.6
Blood Red Count	5.0	48.2	64.0	-5.7	-8.0
Alcohol usually taken with meals	4.9	8.0	9.7	-3.1	-2.5
Mouth/teeth dental problems: Bleeding gums	4.9	6.4	8.8	2.0	3.0
Guilty feelings	4.9	7.4	10.5	2.1	3.2
Chronotype (morning person)	4.6	10.7	11.9	-3.1	-3.5
Trunk fat-free mass	4.5	26.0	31.5	5.6	4.5
Trunk predicted mass	4.5	25.8	31.0	5.6	4.5
Exposure to tobacco smoke outside home	4.4	5.8	7.2	2.1	2.7
Schizophrenia vs Biploar Disorder	4.2	5.5	6.1	2.5	2.2
Ever had hysterectomy (womb removed)	4.0	4.5	4.7	-2.1	-2.2
Medication for hormone replacement therapy	4.0	4.5	6.2	-1.7	-2.5
Tinnitus: Yes, now most or all of the time	4.0	4.6	5.2	-2.0	-2.3
Whole body fat-free mass	3.9	22.4	28.4	5.3	4.0
Whole body water mass	3.9	22.5	28.5	5.3	4.0
Reaction Time	3.8	7.2	8.5	2.9	2.4
Systolic Blood Pressure	3.8	18.9	26.8	-3.3	-5.2
Ever depressed for a whole week	3.8	4.7	6.9	-1.6	-2.6
Leg predicted mass (left)	3.6	18.9	25.1	5.0	3.6
Arm predicted mass (right)	3.6	18.5	24.7	5.0	3.5
Illnesses of siblings: Diabetes	3.6	4.4	6.4	-1.5	-2.5
Crohns Disease (2012)	3.5	5.7	7.5	-2.7	-2.0
Heel T-Score	3.5	27.8	30.6	-5.0	-5.5
Leg fat-free mass (left)	3.5	18.7	24.8	5.0	3.5
Arm predicted mass (left)	3.5	17.8	24.4	4.9	3.3
Medication for cholesterol	3.4	5.2	8.3	1.4	2.9
Height	3.3	62.9	70.2	7.5	8.4
Birth weight of first child	3.3	6.0	8.3	2.9	1.9
Had major operations	3.3	3.8	6.4	-1.1	-2.5
Basal metabolic rate	3.3	18.5	24.4	4.9	3.5
Arm fat-free mass (left)	3.3	16.6	22.7	4.8	3.2
Number of children fathered	3.2	3.6	6.1	-2.5	-1.0
Ever unenthusiastic/disinterested for a whole week	3.1	3.7	7.2	-0.6	-2.7
Arm fat-free mass (right)	3.1	15.8	21.4	4.6	3.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.1	4.0	6.6	-1.2	-2.6
Coronary Artery Disease (CAD)	3.0	3.6	5.4	2.3	1.4
Heel bone mineral density (BMD) T-score, automated (right)	3.0	7.0	9.3	-2.1	-3.0
Leg fat-free mass (right)	3.0	16.2	21.6	4.7	3.3
Major Depression (MDD)	2.9	3.5	5.7	-1.2	-2.4
Neuroticism (2016)	2.9	4.2	5.2	-1.8	-2.3
Had other major operations	2.9	3.5	4.2	-1.7	-2.1
Alcohol intake versus 10 years previously	2.9	4.3	8.6	-0.1	-2.9
Peak expiratory flow (PEF)	2.9	6.8	7.7	-2.8	-2.4
Leg predicted mass (right)	2.9	15.6	20.8	4.6	3.2
Mean Putamen Volume	2.7	3.1	5.0	1.1	2.2
Medication: Metformin	2.7	3.8	7.6	0.2	-2.8
Financial difficulties in last 2 years	2.7	3.7	7.1	-0.5	-2.7
Type 2 Diabetes (T2D) (2012)	2.6	3.0	3.9	2.0	1.4
Smoking Status	2.6	6.1	11.0	3.3	1.1
Supplements: Vitamin C	2.6	3.1	5.2	-1.0	-2.3
Supplements: Zinc	2.4	2.6	4.6	-0.7	-2.2
Diabetes (self-reported)	2.4	3.8	7.5	0.2	-2.7
Noisy workplace	2.4	3.0	3.9	-1.5	-2.0
Lung cancer (father)	2.4	2.8	3.4	1.8	1.5
Hair/balding pattern: Pattern 4	2.4	5.7	8.5	-2.9	-1.7
Medication: Seretide 50 evohaler	2.4	2.8	3.2	-1.6	-1.8
Supplements: Calcium	2.4	2.7	4.3	2.1	1.1
Past tobacco smoking	2.3	4.2	6.3	-2.5	-1.5
Mean time to correctly identify matches	2.3	4.4	5.3	2.3	1.9
Ever smoked	2.2	3.9	5.7	2.4	1.4
Frequency of depressed mood in last 2 weeks	2.1	2.9	4.0	-2.0	-1.3
Standing height	2.1	20.6	24.3	4.1	4.9
Length of working week for main job	2.1	2.3	2.4	-1.5	-1.6
Number of self-reported non-cancer illnesses	2.1	3.6	6.8	-0.7	-2.6
Basal cell carcinoma (self-reported)	2.1	2.5	2.9	1.4	1.7
Comparative body size at age 10	2.0	5.4	6.8	2.6	2.0
Comparative height size at age 10	2.0	10.8	12.7	3.6	3.0
Smoking status: Current	2.0	3.2	5.9	2.4	0.7
Bipolar Disorder (2018)	1.9	2.9	3.8	-2.0	-1.4
Lung FVC	1.9	9.9	11.8	-2.8	-3.4
Sitting height	1.9	13.2	13.8	3.5	3.7
Age at first live birth	1.9	3.4	5.2	1.3	2.3
Diabetes diagnosed by doctor	1.9	3.2	6.0	0.6	-2.4
Breast cancer (self-reported)	1.9	2.2	3.4	1.0	1.9
Crohns Disease (2017)	1.8	3.9	4.4	-2.1	-1.8
Ulcerative Colitis	1.8	2.6	4.0	-2.0	-1.1
Pack years adult smoking proportion	1.8	2.8	5.1	2.3	0.6
Stomach or abdominal pain in last month	1.8	2.3	3.1	-1.2	-1.8
Heart disease (mother)	1.8	2.2	2.7	1.6	1.3
Hearing difficulty/problems: Yes	1.7	2.6	4.5	2.1	0.8
Weight	1.7	8.6	13.7	3.7	1.9
Knee pain experienced in last month	1.7	2.7	4.5	-0.9	-2.1
Medication: Blood pressure	1.7	3.3	4.1	-1.6	-2.0
Alcohol drinker status: Previous	1.7	2.0	3.9	-0.3	-2.0
Impedance of leg (left)	1.6	7.8	13.8	-3.7	-1.4
Hearing difficulty/problems with background noise	1.6	2.6	3.8	1.9	1.2
Alcohol intake frequency.	1.6	3.7	6.5	-1.0	-2.5
Pack years of smoking	1.6	2.4	4.5	2.1	0.5
Blood Platelet Count	1.5	17.9	23.3	-3.5	-4.8
Type 2 Diabetes (T2D) (2018)	1.5	2.8	5.5	-0.3	-2.3
Relative age of first facial hair	1.5	3.1	3.9	2.0	1.5
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	5.1	-1.3	-2.3
High blood pressure	1.5	4.1	6.4	-1.4	-2.5
Tense / ‘highly strung’	1.5	2.4	3.5	-1.2	-1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	2.6	-1.6	-1.0
Hypertension (Self-reported)	1.5	4.1	6.7	-1.2	-2.6
Loneliness, isolation	1.5	2.1	3.2	-1.0	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	1.9	-1.2	-1.4
Blood Eosinophil Count	1.4	10.9	17.9	2.0	4.2
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	2.7	-0.9	-1.6
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	2.3	-0.9	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	4.0	-2.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.4	3.0	5.2	0.9	2.3
Eye problems/disorders: Glaucoma	1.4	1.7	3.1	-0.6	-1.8
Impedance of whole body	1.4	7.0	12.1	-3.5	-1.4
Prostate Cancer	1.3	1.9	3.7	1.9	0.0
Severe depression (siblings)	1.3	1.4	1.6	-1.1	-1.3
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	1.8	-1.1	-1.4
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	2.2	-1.5	-1.2
Medication: Aspirin	1.3	1.7	2.9	0.6	-1.7
Illnesses of father: High blood pressure	1.3	1.6	2.8	-1.7	-0.7
Angina	1.2	1.5	1.8	1.4	-1.1
Illnesses of siblings	1.2	1.7	3.3	0.2	1.8
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	2.4	-1.5	-1.3
Pulse wave Arterial Stiffness index	1.2	1.5	2.6	1.6	0.5
Qualifications: O levels/GCSEs or equivalent	1.2	2.0	3.6	0.6	1.9
Chronic bronchitis/emphysema (mother)	1.2	1.3	1.4	-1.2	-1.1
Angina (self-reported)	1.2	1.6	2.2	1.0	-1.5
Average weekly beer plus cider intake	1.2	1.7	2.6	1.6	0.9
Fractured/broken bones in last 5 years	1.2	1.5	2.7	0.6	1.6
Vascular/heart problems diagnosed by doctor	1.2	3.3	5.5	1.0	2.4
High blood pressure (mother)	1.1	1.5	2.4	-1.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.8	2.5	-1.0	-1.6
Medication: Aspirin	1.1	1.4	2.2	0.8	-1.5
Pain experienced in last month	1.1	1.9	3.5	-0.5	1.9
Depression (Nagel 2018)	1.0	1.5	2.2	-1.5	-0.9
Number of treatments/medications taken	1.0	1.7	2.4	1.0	-1.5
Diabetes (mother)	1.0	1.2	1.6	-0.9	-1.3
Waist circumference	1.0	3.7	7.2	2.7	0.5
Hair/balding pattern: Pattern 2	1.0	1.3	1.7	0.9	1.3
Time employed in main current job	1.0	1.2	1.3	1.0	1.2
Number of live births	1.0	1.4	1.8	-1.0	-1.3
Asthma	1.0	1.9	2.1	-1.4	-1.3
Gout (self-reported)	1.0	1.4	2.0	1.4	0.9
Back pain experienced in last month	1.0	1.5	3.0	0.0	-1.7
LDL Cholesterol	0.9	1.4	2.1	-1.4	-0.9
Townsend deprivation index at recruitment	0.9	1.3	2.3	1.5	0.5
Current tobacco smoking	0.9	1.5	3.1	1.8	0.2
Number of incorrect matches in round	0.9	1.5	2.8	0.4	-1.7
Qualifications: None of the above	0.9	1.9	3.5	-0.5	-1.9
Mouth/teeth dental problems	0.9	1.3	1.4	-1.1	-1.2
Pulse rate	0.9	1.5	2.5	1.6	0.7
Impedance of arm (left)	0.9	4.3	7.8	-2.8	-0.9
High blood pressure (siblings)	0.9	1.3	2.0	-0.8	-1.4
Long-standing illness, disability or infirmity	0.9	1.3	2.4	0.5	-1.6
Medication: Paracetamol	0.9	1.4	2.1	-0.8	-1.4
Unable to work because of sickness or disability	0.9	1.2	2.4	1.6	-0.0
Alzheimer’s Disease (including proxy)	0.8	1.2	2.4	0.0	-1.5
Impedance of leg (right)	0.8	3.9	7.5	-2.7	-0.5
Average weekly fortified wine intake	0.8	0.9	1.6	1.3	-0.5
Nervous feelings	0.8	1.6	2.5	-0.8	1.6
Hip circumference	0.8	3.3	5.4	2.3	1.1
Medication: Cholesterol lowering	0.8	1.3	2.6	-0.0	-1.6
Illnesses of mother	0.8	1.0	1.0	1.0	1.0
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.6	1.3	0.5
Overall health rating	0.8	1.7	2.4	1.0	-1.5
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.7	0.5	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.3	-0.8	-1.1
Irritable Bowel Disease (IBD)	0.7	1.6	1.6	-1.3	-1.3
Blood White Count	0.7	5.3	9.7	-1.0	-3.1
Medication: Ramipril	0.7	0.9	1.8	0.3	-1.3
Medication: Simvastatin	0.7	1.0	1.0	1.0	-1.0
Fluid intelligence score	0.7	1.4	2.2	0.8	1.5
Worrier / anxious feelings	0.7	1.3	2.5	-1.6	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	-0.0	-1.3
Arm fat mass (right)	0.7	2.8	5.4	2.3	0.5
Birth weight	0.7	1.6	2.6	-1.6	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	1.7	-0.1	1.3
Leg fat mass (right)	0.7	2.5	4.8	2.2	0.4
Suffer from ‘nerves’	0.7	1.2	2.3	-0.2	1.5
Illnesses of father: Heart disease	0.7	1.0	1.5	1.2	0.7
Commuting to job workplace: Walk	0.7	0.7	0.8	0.9	0.8
Asthma (self-reported)	0.7	1.5	1.5	-1.2	-1.2
Lupus	0.6	0.9	1.3	1.1	-0.8
Cardiovascular Disease	0.6	2.0	3.8	-0.5	-1.9
Age when periods started (menarche)	0.6	1.6	2.2	-1.5	0.9
Impedance of arm (right)	0.6	2.6	5.2	-2.3	-0.3
Falls in the last year	0.6	0.8	1.5	-0.3	-1.2
Number of full brothers	0.6	0.7	1.3	0.3	1.2
Pulse rate, automated reading	0.6	1.9	2.6	1.6	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	1.5	0.0	1.2
Smoking status: Previous	0.6	0.9	1.7	1.3	0.4
Arm fat mass (left)	0.6	2.6	5.0	2.2	0.4
Commuting to job workplace: Public transport	0.6	0.7	0.7	0.8	0.9
Heart disease (siblings)	0.6	0.7	1.4	-0.0	-1.2
Leg fat mass (left)	0.6	2.3	4.5	2.1	0.3
Bipolar Disorder or Schizophrenia	0.5	1.2	2.0	-1.4	-0.7
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	0.0	-1.1
Alzheimer’s Disease (in father)	0.5	0.5	0.9	-0.3	-1.0
Hair Pigment	0.5	14.3	22.4	-2.5	-4.7
Fed-up feelings	0.5	0.9	1.3	0.8	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	1.3	-1.1	0.2
Relative age voice broke	0.5	0.7	1.1	1.0	0.6
Taking other prescription medications	0.5	0.8	0.9	0.9	-0.9
Multivitamins +/- minerals	0.5	0.7	1.3	0.3	-1.1
Medication: Atenolol	0.5	0.6	0.7	0.8	-0.7
Body mass index (BMI)	0.5	2.1	4.2	2.0	-0.4
Trunk fat mass	0.5	2.2	4.1	2.0	0.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	2.6	-1.6	-0.9
Mouth/teeth dental problems: Dentures	0.5	0.9	1.2	-0.8	-1.1
Pulse wave peak to peak time	0.5	0.6	1.3	-1.1	-0.1
Health satisfaction	0.5	0.7	1.1	1.1	-0.5
Whole body fat mass	0.5	2.2	4.2	2.0	0.4
Number of full sisters	0.5	0.7	0.8	-0.9	-0.7
Age at last live birth	0.5	0.8	1.2	1.1	0.6
Ever had bowel cancer screening	0.5	0.6	0.7	-0.8	-0.6
Osteoarthritis (self-reported)	0.5	0.6	1.2	0.1	-1.1
Average weekly champagne plus white wine intake	0.5	0.7	1.3	-0.1	1.1
Hearing aid user	0.5	0.6	0.9	-0.5	-1.0
Cholesterol lowering medication	0.5	0.7	1.4	-0.2	-1.2
Neuroticism (Nagel 2018)	0.4	1.0	1.6	0.6	1.3
Vitamin and mineral supplements	0.4	0.5	1.0	-0.3	1.0
Hand grip strength (right)	0.4	1.1	2.2	-1.5	-0.2
Supplements: Glucosamine	0.4	0.5	0.9	0.2	-0.9
Medication: Levothyroxine sodium	0.4	0.8	1.4	-0.3	1.2
Forced vital capacity (FVC)	0.4	1.4	2.0	-1.4	-0.9
Heart attack	0.4	0.5	1.0	-0.1	-1.0
Father’s age at death	0.4	0.5	0.9	-0.1	-1.0
Blood clot in the leg (DVT)	0.4	0.6	0.8	0.9	0.6
Worry too long after embarrassment	0.4	0.7	1.3	0.2	1.1
Medication: Blood pressure	0.4	0.8	1.3	1.1	-0.5
Medication: Allopurinol	0.4	0.6	1.1	1.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.9	0.1	1.0
Financial situation satisfaction	0.4	0.5	0.7	0.8	-0.6
High cholesterol (Self-reported)	0.4	0.7	1.4	-0.1	-1.2
Ovarian Cancer	0.3	0.3	0.5	0.4	0.7
Body Mass Index (BMI) (2010)	0.3	0.4	0.5	0.5	0.7
Fasting Glucose	0.3	0.3	0.6	0.8	0.2
Schizophrenia (2014)	0.3	0.8	0.8	0.8	0.9
BMI	0.3	1.5	2.9	1.7	-0.5
Allergy or Eczema	0.3	0.7	1.3	-0.3	-1.2
Respiratory disease	0.3	0.7	1.2	-1.1	-0.5
Hand grip strength (left)	0.3	0.8	1.6	-1.3	0.2
Medication: Co-codamol	0.3	0.4	0.6	-0.4	-0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	0.5	-0.7	-0.5
Allergy	0.3	0.8	1.0	1.0	0.7
Hair/balding pattern: Pattern 3	0.3	0.4	0.7	-0.9	0.1
Medication: Paracetamol	0.3	0.5	1.0	-0.1	-1.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.8	-0.5	0.9
Glaucoma (self-reported)	0.3	0.4	0.5	0.7	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.1	-0.5	1.0
Wheeze or whistling in the chest in last year	0.3	0.5	0.8	-0.9	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.6	0.6	-0.7	0.8
Average weekly red wine intake	0.3	0.4	0.7	-0.9	0.1
Age started oral contraceptive pill	0.3	0.3	0.6	0.8	-0.3
Diastolic blood pressure, automated reading	0.3	0.9	1.6	-0.4	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.8	-0.9	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.5	0.7	0.4
Worry (Nagel 2018)	0.2	0.4	0.6	-0.6	0.8
Bipolar Disorder (2011)	0.2	0.2	0.4	-0.6	-0.3
HbA1C	0.2	0.2	0.4	-0.2	-0.7
Triglycerides	0.2	0.3	0.6	0.8	-0.1
Hypothyroidism (self reported)	0.2	0.5	0.9	-0.4	0.9
Neuroticism	0.2	0.5	0.7	0.6	0.8
Diabetes (father)	0.2	0.3	0.4	-0.4	-0.7
Maternal smoking around birth	0.2	0.4	0.7	0.8	-0.2
Qualifications: CSEs or equivalent	0.2	0.3	0.4	-0.6	-0.5
Arm fat percentage (right)	0.2	0.6	0.8	0.9	-0.7
Happiness	0.2	0.2	0.2	-0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	0.7	0.2
Prospective memory result	0.2	0.2	0.4	-0.6	-0.2
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	0.2	-0.6
Headache pain in last month	0.2	0.3	0.6	0.8	0.2
Medication: Amlodipine	0.2	0.2	0.5	0.7	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.4	-0.6	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.7	0.1
Neck or shoulder pain in last month	0.2	0.3	0.5	-0.1	-0.7
Migraine (self-reported)	0.2	0.3	0.4	-0.5	-0.6
Medication: Omeprazole	0.2	0.2	0.5	-0.0	0.7
Family relationship satisfaction	0.2	0.2	0.4	0.3	0.6
Arm fat percentage (left)	0.2	0.6	0.7	0.9	-0.7
Mood swings	0.2	0.3	0.4	-0.6	-0.4
Friendships satisfaction	0.2	0.2	0.4	-0.6	0.2
Eye problems/disorders: Cataract	0.2	0.2	0.3	-0.4	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.6	-0.8	0.2
Medication: Gliclazide	0.2	0.2	0.4	0.6	-0.1
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	0.5	-0.4
Miserableness	0.2	0.4	0.7	-0.3	0.8
Medication: Bendroflumethiazide	0.2	0.4	0.7	0.1	-0.8
Alcohol drinker status: Never	0.2	0.2	0.3	-0.4	0.5
Leg fat percentage (left)	0.2	0.6	0.8	0.6	-0.9
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.5	0.2	-0.7
Depressed Affect (Nagel 2018)	0.1	0.2	0.4	0.6	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.5	0.3
Age at First Birth	0.1	0.2	0.4	-0.0	0.6
HDL Cholesterol	0.1	0.2	0.4	-0.6	0.1
Primary Biliary Cirrhosis	0.1	0.1	0.1	-0.3	0.2
Rheumatoid Arthritis	0.1	0.2	0.2	0.5	0.4
Tanning	0.1	0.9	1.1	-0.9	-1.1
Average weekly spirits intake	0.1	0.2	0.3	0.2	-0.6
Sensitivity / hurt feelings	0.1	0.2	0.3	-0.5	-0.3
Trunk fat percentage	0.1	0.4	0.6	0.5	-0.8
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	-0.4	0.1
Had menopause	0.1	0.1	0.1	0.4	-0.3
Pain all over the body in last month	0.1	0.1	0.2	0.4	0.2
Neuroticism score	0.1	0.1	0.2	-0.5	0.1
Depression (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.8	-0.9	-0.2
Exposure to tobacco smoke at home	0.1	0.1	0.1	0.4	0.2
Breastfed as a baby	0.1	0.1	0.3	-0.0	-0.5
Pulse wave reflection index	0.1	0.1	0.1	-0.3	-0.3
Loud music exposure frequency	0.1	0.1	0.3	0.0	0.5
Forced vital capacity (FVC), Best measure	0.1	0.3	0.6	-0.8	-0.1
Body fat percentage	0.1	0.6	0.8	0.6	-0.9
Leg fat percentage (right)	0.1	0.5	0.6	0.8	-0.7
Chest pain or discomfort	0.1	0.2	0.3	0.3	-0.5
Leg pain on walking	0.1	0.2	0.2	-0.4	-0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.2	0.4
Qualifications: nursing, teaching	0.1	0.1	0.2	0.3	0.5
Mineral and other dietary supplements	0.1	0.2	0.4	0.1	0.6
Osteoporosis (self-reported)	0.1	0.2	0.3	-0.6	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.2	-0.4	-0.3
Mother’s age at death	0.1	0.1	0.1	-0.4	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	0.5	-0.4
Medication: Atorvastatin	0.1	0.1	0.3	0.1	-0.5
Myopia	0.1	0.1	0.2	0.4	0.2
Schizophrenia (2018)	0.0	0.1	0.1	-0.2	0.3
Ulcerative Colitis (UC)	0.0	0.0	0.1	-0.3	0.0
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	-0.0	0.4
Waist Hip Ratio (WHR)	0.0	0.2	0.3	0.5	-0.3
Lung FEV1/FVC ratio	0.0	0.0	0.0	-0.1	0.0
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	-0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.1	0.2
Shortness of breath walking on level ground	0.0	0.0	0.0	0.0	0.1
Qualifications: College or University degree	0.0	0.1	0.1	0.1	0.4
Emphysema/chronic bronchitis	0.0	0.0	0.0	-0.1	-0.0
Medication: Ibuprofen	0.0	0.0	0.0	0.0	-0.2
Medication: Lisinopril	0.0	0.0	0.0	-0.0	0.2
Irritability	0.0	0.0	0.0	0.2	0.2
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.1	-0.1
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.2	0.1

Hub : Genes

MTERF

Models

Trait associations