[Hub]/) : Traits : Whole body water mass :

chr16:88,074,533-90,172,696

Best TWAS P=1.44e-14 · Best GWAS P=4.74e-16 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CTU2 0.10 0.07 lasso 5 0.08 4.0e-10 -4.4 5.4 6.9e-08 -0.43 1.00 0.00 TRUE
2 CommonMind Brain Pre-frontal Cortex SPG7 0.14 0.06 blup 445 0.10 3.2e-12 6.3 -6.0 1.5e-09 -0.02 0.01 0.99 FALSE
3 GTEx Artery Aorta RPL13 0.19 0.20 lasso 5 0.17 1.7e-09 6.1 -6.7 1.9e-11 0.05 0.02 0.98 FALSE
4 GTEx Breast Mammary Tissue RPL13 0.09 0.05 enet 7 0.04 5.3e-03 6.9 -6.4 1.5e-10 0.00 0.02 0.94 FALSE
5 GTEx Cells Transformed fibroblasts RPL13 0.10 0.08 enet 8 0.09 3.7e-07 5.6 -6.7 1.8e-11 0.09 0.03 0.97 TRUE
6 GTEx Cells Transformed fibroblasts RP11-104N10.1 0.07 0.10 lasso 2 0.08 8.3e-07 -5.2 -5.2 1.5e-07 -0.17 0.95 0.04 FALSE
7 GTEx Colon Sigmoid RPL13 0.17 0.18 lasso 1 0.16 3.1e-06 6.1 -6.1 1.0e-09 0.08 0.02 0.98 FALSE
8 GTEx Colon Sigmoid CDK10 0.37 0.12 lasso 8 0.22 2.2e-08 3.8 -5.7 1.2e-08 -0.21 0.60 0.03 TRUE
9 GTEx Colon Sigmoid RP11-104N10.1 0.14 0.00 lasso 2 0.02 8.3e-02 -5.5 -5.5 3.7e-08 -0.17 0.10 0.16 FALSE
10 GTEx Colon Transverse RPL13 0.23 0.17 lasso 4 0.16 3.7e-08 6.7 -7.7 1.4e-14 0.01 0.01 0.99 TRUE
11 GTEx Esophagus Muscularis RPL13 0.17 0.12 lasso 3 0.11 2.4e-07 6.7 -7.0 3.4e-12 0.06 0.01 0.99 FALSE
12 GTEx Muscle Skeletal RPL13 0.10 0.09 lasso 5 0.10 3.3e-10 6.1 -6.4 1.6e-10 0.08 0.03 0.97 FALSE
13 GTEx Muscle Skeletal SPG7 0.24 0.22 lasso 5 0.23 8.9e-23 -5.2 -6.5 8.3e-11 -0.11 0.98 0.02 FALSE
14 GTEx Nerve Tibial RPL13 0.10 0.07 lasso 3 0.07 2.0e-05 6.5 -6.1 1.0e-09 0.09 0.03 0.97 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic RPL13 0.16 0.15 lasso 4 0.15 2.0e-08 6.5 -6.5 5.6e-11 0.09 0.03 0.97 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic RP11-104N10.1 0.11 0.04 lasso 4 0.03 5.2e-03 -5.5 -5.4 5.5e-08 -0.13 0.14 0.45 FALSE
17 GTEx Skin Sun Exposed Lower leg RPL13 0.11 0.13 enet 7 0.12 1.7e-10 5.7 -6.0 2.6e-09 0.06 0.08 0.92 FALSE
18 GTEx Skin Sun Exposed Lower leg SPG7 0.09 0.05 lasso 2 0.03 1.5e-03 6.7 -6.6 4.1e-11 0.08 0.02 0.98 FALSE
19 GTEx Testis RPL13 0.25 0.22 lasso 5 0.21 1.6e-09 6.1 -6.2 7.2e-10 0.09 0.03 0.97 FALSE
20 GTEx Testis RP5-1142A6.2 0.21 0.13 lasso 4 0.12 7.2e-06 -5.2 -6.3 2.3e-10 0.60 0.15 0.34 TRUE
21 GTEx Thyroid RPL13 0.13 0.05 enet 10 0.06 1.4e-05 6.6 -7.4 1.6e-13 -0.02 0.02 0.98 FALSE
22 GTEx Whole Blood SPG7 0.06 0.05 lasso 3 0.05 3.9e-05 6.5 -7.0 2.0e-12 0.01 0.04 0.94 FALSE
23 GTEx Whole Blood CTD-2555A7.3 0.10 0.00 lasso 5 0.01 1.0e-01 3.3 6.3 2.3e-10 -0.19 0.13 0.12 TRUE
24 METSIM Adipose RPL13 0.05 0.05 enet 5 0.05 1.0e-07 6.6 -6.5 1.0e-10 0.07 0.02 0.98 FALSE
25 NTR Blood RPL13 0.02 0.01 bslmm 365 0.01 5.9e-05 6.7 5.7 1.0e-08 -0.12 0.02 0.98 FALSE
26 YFS Blood SPG7 0.08 0.11 lasso 6 0.11 6.9e-34 -5.4 -5.5 4.6e-08 -0.18 0.98 0.02 TRUE
27 The Cancer Genome Atlas Bladder Urothelial Carcinoma CTU2 0.06 0.03 blup 67 0.03 1.3e-03 -1.5 5.3 1.1e-07 -0.41 0.05 0.09 TRUE
28 The Cancer Genome Atlas Bladder Urothelial Carcinoma SPG7 0.05 0.03 lasso 3 0.03 1.8e-03 6.4 -6.3 2.8e-10 0.08 0.02 0.89 FALSE
29 The Cancer Genome Atlas Esophageal Carcinoma RPL13 0.14 0.07 lasso 3 0.04 2.6e-02 6.4 -6.6 5.3e-11 0.07 0.01 0.83 FALSE
30 The Cancer Genome Atlas Glioblastoma Multiforme SNAI3 0.19 0.06 enet 7 0.12 1.6e-04 3.2 -6.2 4.5e-10 0.44 0.00 0.86 TRUE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SPG7 0.05 0.05 lasso 5 0.05 1.9e-06 6.4 -6.4 1.3e-10 0.08 0.02 0.98 FALSE
32 The Cancer Genome Atlas Brain Lower Grade Glioma MGC23284 0.09 0.04 enet 19 0.03 1.7e-04 -4.3 -5.3 1.2e-07 0.45 0.09 0.86 FALSE
33 The Cancer Genome Atlas Brain Lower Grade Glioma SPG7 0.03 0.02 blup 58 0.03 4.1e-04 5.6 -6.9 4.4e-12 -0.01 0.02 0.73 FALSE
34 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPL13 0.03 0.01 blup 41 0.02 8.5e-03 6.3 -7.0 3.7e-12 0.01 0.01 0.75 FALSE
35 The Cancer Genome Atlas Pancreatic Adenocarcinoma SPG7 0.11 0.09 lasso 2 0.08 2.5e-04 6.6 -6.6 3.8e-11 0.07 0.02 0.95 FALSE
36 The Cancer Genome Atlas Stomach Adenocarcinoma RPL13 0.04 0.03 blup 41 0.03 2.2e-03 6.1 -7.0 1.8e-12 0.06 0.02 0.87 TRUE
37 The Cancer Genome Atlas Thyroid Carcinoma SPG7 0.10 0.09 lasso 4 0.11 1.9e-10 6.6 -5.5 3.1e-08 0.14 0.01 0.99 FALSE