[Hub]/) : Traits : Whole body water mass :

chr5:41,211,789-44,208,409

Best TWAS P=3.41e-23 · Best GWAS P=8.73e-24 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GHR 0.25 0.07 bslmm 382 0.13 2.6e-15 -6.6 6.9 5.0e-12 0.20 0.37 0.63 FALSE
2 GTEx Adipose Subcutaneous CCDC152 0.09 0.04 lasso 4 0.02 6.4e-03 9.7 9.8 1.7e-22 0.46 0.07 0.92 FALSE
3 GTEx Adipose Visceral Omentum CCDC152 0.09 0.06 lasso 9 0.05 1.9e-03 9.6 9.1 1.4e-19 0.45 0.07 0.60 FALSE
4 GTEx Artery Aorta CCDC152 0.31 0.24 lasso 8 0.24 2.5e-13 9.6 8.8 8.6e-19 0.45 0.09 0.91 FALSE
5 GTEx Artery Coronary CCDC152 0.20 0.13 lasso 2 0.12 7.7e-05 9.6 9.6 7.0e-22 0.46 0.08 0.88 FALSE
6 GTEx Artery Tibial CCDC152 0.22 0.17 enet 35 0.18 1.8e-14 9.6 7.6 2.9e-14 0.43 0.09 0.91 FALSE
7 GTEx Brain Caudate basal ganglia C5orf34 0.14 -0.01 enet 14 0.00 3.3e-01 3.3 5.4 6.9e-08 0.07 0.03 0.19 TRUE
8 GTEx Brain Frontal Cortex BA9 GHR 0.14 0.02 lasso 9 0.06 9.9e-03 7.5 -5.8 8.2e-09 -0.31 0.13 0.05 TRUE
9 GTEx Breast Mammary Tissue (Female) SEPP1 0.15 0.00 enet 29 0.02 1.0e-01 -2.1 -5.4 6.2e-08 -0.23 0.06 0.09 TRUE
10 GTEx Esophagus Muscularis CCDC152 0.13 0.09 lasso 8 0.10 7.9e-07 8.5 8.3 8.9e-17 0.48 0.11 0.88 TRUE
11 GTEx Nerve Tibial CCDC152 0.16 0.06 enet 25 0.06 2.9e-05 9.6 6.3 2.8e-10 0.19 0.13 0.86 TRUE
12 GTEx Stomach SERBP1P6 0.12 0.03 enet 16 0.01 6.7e-02 -4.5 7.5 7.4e-14 0.24 0.08 0.10 FALSE
13 GTEx Thyroid GHR 0.08 0.04 enet 25 0.04 2.5e-04 8.5 5.2 2.2e-07 0.33 0.09 0.37 FALSE
14 GTEx Thyroid C5orf34 0.08 0.08 lasso 3 0.06 1.4e-05 4.9 5.1 2.7e-07 0.08 0.00 0.98 FALSE
15 GTEx Thyroid CCDC152 0.10 0.07 lasso 4 0.04 4.2e-04 9.6 9.6 5.5e-22 0.45 0.08 0.90 FALSE
16 ROSMAP Brain Pre-frontal Cortex ZNF131 0.18 0.06 lasso 15 0.12 3.3e-15 -3.9 5.2 2.2e-07 0.05 1.00 0.00 FALSE
17 ROSMAP Brain Pre-frontal Cortex CCDC152 0.20 0.09 lasso 10 0.09 5.2e-12 2.9 5.8 7.8e-09 0.17 0.99 0.01 FALSE
18 ROSMAP Brain Pre-frontal Cortex C5orf51 0.03 0.01 bslmm 298 0.02 1.9e-03 -3.2 5.4 7.5e-08 0.12 0.13 0.58 TRUE
19 ROSMAP Brain Pre-frontal Cortex SEPP1 0.18 0.19 lasso 11 0.21 1.3e-26 9.1 -9.6 5.5e-22 -0.48 0.07 0.93 FALSE
20 YFS Blood CCDC152 0.07 0.06 enet 16 0.06 2.0e-19 9.7 9.9 3.4e-23 0.47 0.06 0.94 TRUE
21 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC152 0.14 0.02 blup 40 0.03 2.5e-06 9.1 -5.1 3.0e-07 -0.38 0.18 0.59 TRUE
22 The Cancer Genome Atlas Breast Invasive Carcinoma SEPP1 0.01 0.00 enet 7 0.01 1.5e-03 9.2 -7.5 9.1e-14 -0.39 0.02 0.51 TRUE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC152 0.06 0.06 blup 40 0.07 1.6e-08 8.9 -9.6 8.5e-22 -0.43 0.03 0.97 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC152 0.15 0.12 lasso 6 0.12 1.0e-12 9.2 -9.2 2.8e-20 -0.46 0.34 0.66 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma GHR 0.12 0.11 enet 6 0.13 2.5e-13 -7.8 -8.6 9.5e-18 -0.26 1.00 0.00 TRUE
26 The Cancer Genome Atlas Prostate Adenocarcinoma SEPP1 0.06 0.02 blup 38 0.04 5.2e-05 8.5 -8.8 1.0e-18 -0.40 0.20 0.73 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma MGC42105 0.04 0.01 blup 63 0.01 4.3e-02 -3.8 -5.5 4.1e-08 -0.10 0.00 0.05 TRUE