[Hub]/) : Traits : Basal metabolic rate : ← →

chr8:8,092,025-12,973,575

Best TWAS P=7.04e-11 · Best GWAS P=4.24e-10 conditioned to 0.15

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
56	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ERI1	0.05	0.01	blup	72	0.01	5.0e-02	6.2	-6.5	7.0e-11	-0.84	0.00	0.89	TRUE
19	GTEx	Cells Transformed fibroblasts	ERI1	0.34	0.35	lasso	7	0.35	1.9e-27	6.2	-6.3	2.6e-10	-0.97	0.00	1.00	FALSE
27	GTEx	Esophagus Muscularis	AF131215.9	0.14	0.17	enet	16	0.17	1.6e-10	-5.5	6.2	4.9e-10	0.60	0.08	0.91	FALSE
42	GTEx	Skin Sun Exposed Lower leg	AF131215.9	0.19	0.17	enet	29	0.21	3.9e-17	-5.5	6.1	8.7e-10	0.61	0.13	0.87	FALSE
50	ROSMAP	Brain Pre-frontal Cortex	XKR6	0.11	0.10	enet	23	0.13	1.2e-16	-4.7	6.1	1.4e-09	0.63	0.21	0.79	FALSE
30	GTEx	Heart Left Ventricle	AF131215.9	0.07	0.10	enet	8	0.10	9.4e-06	-5.5	6.0	2.0e-09	0.59	0.08	0.91	FALSE
45	GTEx	Thyroid	AF131215.2	0.11	0.15	enet	17	0.18	1.2e-13	-4.9	6.0	2.0e-09	0.60	0.20	0.80	FALSE
36	GTEx	Pancreas	AF131215.9	0.25	0.24	enet	14	0.22	1.0e-09	5.4	5.9	2.9e-09	0.60	0.06	0.94	FALSE
52	ROSMAP	Brain Pre-frontal Cortex	AF131215.3	0.08	0.10	lasso	7	0.12	8.3e-16	5.5	5.9	3.2e-09	0.64	0.03	0.97	FALSE
44	GTEx	Testis	AF131215.2	0.28	0.18	enet	41	0.17	8.0e-08	-4.9	5.9	3.5e-09	0.47	0.52	0.48	FALSE
35	GTEx	Pancreas	AF131215.2	0.16	0.16	enet	17	0.15	9.1e-07	-5.5	5.9	3.7e-09	0.62	0.08	0.92	FALSE
48	GTEx	Vagina	AF131215.9	0.21	0.11	lasso	9	0.08	6.3e-03	5.7	5.8	4.9e-09	0.57	0.05	0.90	FALSE
29	GTEx	Heart Left Ventricle	AF131215.2	0.05	0.01	enet	11	0.01	1.5e-01	5.6	5.8	5.4e-09	0.61	0.07	0.86	FALSE
24	GTEx	Esophagus Mucosa	AF131215.9	0.18	0.16	lasso	14	0.19	1.6e-12	5.2	5.8	6.1e-09	0.63	0.06	0.94	FALSE
49	NTR	Blood	MSRA	0.02	0.01	blup	833	0.01	2.3e-05	4.1	-5.8	6.5e-09	-0.58	0.20	0.79	FALSE
11	GTEx	Artery Aorta	AF131215.2	0.09	0.09	lasso	7	0.08	2.0e-05	-5.2	5.8	7.4e-09	0.62	0.08	0.92	FALSE
9	GTEx	Adrenal Gland	AF131215.9	0.18	0.16	lasso	10	0.18	3.5e-07	5.5	5.8	8.0e-09	0.62	0.04	0.96	FALSE
12	GTEx	Artery Aorta	AF131215.9	0.13	0.05	lasso	6	0.07	1.3e-04	5.4	5.8	8.1e-09	0.61	0.07	0.92	FALSE
6	GTEx	Adipose Visceral Omentum	AF131215.9	0.18	0.16	lasso	7	0.16	2.0e-08	5.6	5.8	9.2e-09	0.61	0.04	0.96	FALSE
8	GTEx	Adrenal Gland	AF131215.2	0.20	0.16	enet	12	0.13	2.2e-05	5.5	5.7	9.6e-09	0.61	0.04	0.96	FALSE
33	GTEx	Nerve Tibial	AF131215.2	0.19	0.18	lasso	12	0.23	3.5e-16	-4.9	5.7	9.8e-09	0.60	0.19	0.81	FALSE
31	GTEx	Lung	AF131215.2	0.12	0.08	lasso	5	0.08	1.0e-06	-5.5	5.7	1.0e-08	0.53	0.09	0.91	FALSE
5	GTEx	Adipose Visceral Omentum	AF131215.2	0.12	0.08	lasso	6	0.06	4.6e-04	5.6	5.7	1.3e-08	0.61	0.09	0.89	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FAM86B1	0.02	0.02	lasso	3	0.01	1.3e-02	4.9	5.7	1.6e-08	0.59	0.01	0.96	FALSE
10	GTEx	Artery Aorta	ERI1	0.11	0.08	lasso	5	0.10	5.1e-06	6.2	-5.7	1.6e-08	-0.92	0.00	1.00	FALSE
37	GTEx	Prostate	AF131215.2	0.18	0.02	lasso	6	0.02	9.6e-02	3.7	5.6	1.8e-08	0.57	0.07	0.54	FALSE
13	GTEx	Brain Cerebellar Hemisphere	AF131215.2	0.15	0.17	lasso	3	0.09	3.0e-03	-5.5	5.6	1.9e-08	0.56	0.08	0.74	FALSE
47	GTEx	Uterus	AF131215.2	0.17	0.07	enet	13	0.09	7.1e-03	5.5	5.6	1.9e-08	0.62	0.07	0.76	FALSE
54	ROSMAP	Brain Pre-frontal Cortex	AF131215.2	0.49	0.57	lasso	7	0.57	9.0e-89	-5.5	5.6	2.0e-08	0.53	0.08	0.92	FALSE
32	GTEx	Lung	AF131215.9	0.15	0.18	lasso	4	0.15	1.5e-11	-5.5	5.6	2.2e-08	0.52	0.09	0.91	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.9	0.17	0.14	lasso	8	0.19	9.4e-11	-5.5	5.6	2.7e-08	0.59	0.10	0.90	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FAM90A25P	0.11	0.08	lasso	3	0.08	1.4e-09	5.2	5.6	2.8e-08	0.54	0.00	1.00	FALSE
51	ROSMAP	Brain Pre-frontal Cortex	FAM66A	0.23	0.26	enet	29	0.30	4.7e-39	5.5	5.6	2.8e-08	0.53	0.00	1.00	FALSE
21	GTEx	Colon Sigmoid	AF131215.9	0.11	0.17	enet	5	0.09	4.9e-04	-5.5	5.5	3.4e-08	0.56	0.09	0.80	FALSE
58	The Cancer Genome Atlas	Lung Adenocarcinoma	ERI1	0.06	0.04	blup	72	0.04	1.5e-05	4.9	-5.5	3.6e-08	-0.89	0.04	0.96	FALSE
40	GTEx	Skin Sun Exposed Lower leg	AF131215.2	0.14	0.11	lasso	9	0.16	4.3e-13	-4.9	5.5	3.7e-08	0.58	0.36	0.64	FALSE
3	GTEx	Adipose Subcutaneous	AF131215.2	0.24	0.15	lasso	7	0.14	3.5e-11	-5.2	5.5	3.9e-08	0.59	0.20	0.80	FALSE
22	GTEx	Colon Transverse	AF131215.9	0.12	0.14	enet	18	0.12	4.0e-06	-5.5	5.5	4.1e-08	0.55	0.08	0.92	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	AF131215.2	0.20	0.10	enet	14	0.11	1.5e-04	-5.5	5.5	4.8e-08	0.61	0.14	0.83	FALSE
46	GTEx	Thyroid	AF131215.9	0.11	0.08	enet	16	0.17	4.7e-13	-5.5	5.5	4.8e-08	0.59	0.10	0.90	FALSE
34	GTEx	Nerve Tibial	AF131215.9	0.17	0.17	lasso	4	0.18	5.0e-13	-5.5	5.4	5.6e-08	0.53	0.10	0.90	FALSE
18	GTEx	Cells EBV-transformed lymphocytes	AF131215.9	0.20	0.15	enet	19	0.13	5.6e-05	-5.5	5.4	5.7e-08	0.59	0.13	0.83	FALSE
23	GTEx	Esophagus Mucosa	AF131215.2	0.15	0.14	enet	15	0.18	4.3e-12	-4.9	5.4	5.7e-08	0.62	0.44	0.55	FALSE
53	ROSMAP	Brain Pre-frontal Cortex	RP11-481A20.11	0.06	0.04	blup	286	0.04	2.2e-06	5.2	5.4	5.9e-08	0.60	0.01	0.99	FALSE
25	GTEx	Esophagus Muscularis	ERI1	0.12	0.09	enet	13	0.08	7.7e-06	5.4	-5.4	6.1e-08	-0.86	0.06	0.94	FALSE
4	GTEx	Adipose Subcutaneous	AF131215.9	0.20	0.12	enet	60	0.17	1.1e-13	-5.2	5.4	7.7e-08	0.47	0.08	0.92	FALSE
15	GTEx	Breast Mammary Tissue	AF131215.9	0.10	0.10	lasso	8	0.12	8.7e-07	-4.4	5.4	7.9e-08	0.64	0.17	0.82	FALSE
14	GTEx	Breast Mammary Tissue	AF131215.2	0.16	0.15	lasso	6	0.12	1.1e-06	-5.2	5.4	8.5e-08	0.64	0.25	0.74	FALSE
7	GTEx	Adrenal Gland	FAM86B3P	0.16	0.00	enet	18	0.03	2.2e-02	4.5	-5.3	9.0e-08	-0.43	0.05	0.16	FALSE
38	GTEx	Skin Not Sun Exposed Suprapubic	AF131215.2	0.16	0.11	enet	21	0.20	3.9e-11	-4.9	5.3	9.8e-08	0.61	0.10	0.90	FALSE
57	The Cancer Genome Atlas	Breast Invasive Carcinoma	RP1L1	0.02	0.01	lasso	2	0.01	4.1e-03	5.2	5.3	1.3e-07	0.49	0.01	0.84	FALSE
41	GTEx	Skin Sun Exposed Lower leg	FAM85A	0.09	0.04	enet	28	0.04	1.4e-04	-4.1	5.2	1.5e-07	0.44	0.08	0.83	FALSE
43	GTEx	Spleen	AF131215.2	0.16	0.08	enet	14	0.06	1.1e-02	-5.5	5.2	1.5e-07	0.60	0.05	0.87	FALSE
55	ROSMAP	Brain Pre-frontal Cortex	FAM85A	0.11	0.07	enet	23	0.11	4.3e-14	5.5	5.2	1.7e-07	0.56	0.00	1.00	FALSE
20	GTEx	Colon Sigmoid	AF131215.2	0.10	0.00	enet	7	0.02	5.0e-02	5.3	5.2	1.9e-07	0.64	0.13	0.52	FALSE
59	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ZNF705D	0.23	0.20	lasso	3	0.24	4.7e-09	5.5	-5.2	2.4e-07	-0.51	0.00	1.00	FALSE
26	GTEx	Esophagus Muscularis	FAM85A	0.10	0.01	enet	20	0.04	2.7e-03	-4.0	5.2	2.6e-07	0.46	0.06	0.86	FALSE
16	GTEx	Breast Mammary Tissue (Female)	AF131215.9	0.04	-0.01	enet	6	0.02	7.3e-02	-3.8	5.2	2.7e-07	0.62	0.07	0.22	FALSE
28	GTEx	Heart Atrial Appendage	AF131215.2	0.39	0.13	enet	26	0.21	6.6e-10	-4.9	5.1	3.0e-07	0.59	0.40	0.60	FALSE