[Hub]/) : Traits : Basal metabolic rate :

chr19:9,637,688-11,873,382

Best TWAS P=4.51e-16 · Best GWAS P=1.07e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex S1PR2 0.07 0.02 bslmm 369 0.03 5.3e-05 -5.0 5.3 1.2e-07 0.31 0.33 0.12 FALSE
2 GTEx Esophagus Mucosa SLC44A2 0.13 0.00 lasso 6 0.02 1.4e-02 4.8 -6.1 1.2e-09 -0.46 0.07 0.56 FALSE
3 GTEx Esophagus Mucosa ILF3-AS1 0.11 0.00 lasso 4 0.00 2.5e-01 7.9 -6.2 6.2e-10 -0.77 0.02 0.85 FALSE
4 GTEx Muscle Skeletal SLC44A2 0.19 0.18 lasso 5 0.19 5.1e-18 6.9 7.4 1.5e-13 0.79 0.83 0.17 FALSE
5 GTEx Nerve Tibial ILF3-AS1 0.14 0.04 lasso 3 0.08 3.8e-06 7.9 -6.5 6.1e-11 -0.77 0.01 0.98 FALSE
6 GTEx Skin Sun Exposed Lower leg SMARCA4 0.15 0.10 enet 25 0.15 1.4e-12 2.3 -5.2 1.6e-07 -0.61 1.00 0.00 FALSE
7 GTEx Testis PDE4A 0.20 0.02 enet 39 0.04 6.4e-03 5.5 6.3 2.9e-10 0.06 0.06 0.04 TRUE
8 GTEx Vagina CTD-2369P2.2 0.50 -0.01 lasso 9 0.01 2.0e-01 5.0 5.3 1.3e-07 0.01 0.22 0.12 TRUE
9 GTEx Whole Blood CTD-2369P2.8 0.12 0.11 lasso 3 0.10 9.2e-10 5.9 6.4 1.3e-10 0.06 1.00 0.00 TRUE
10 NTR Blood SMARCA4 0.07 0.06 lasso 11 0.06 9.0e-18 5.0 -5.3 9.9e-08 -0.43 1.00 0.00 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma S1PR2 0.02 0.00 blup 32 0.01 1.5e-02 -5.5 5.5 4.0e-08 0.04 0.00 0.61 TRUE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FDX1L 0.06 0.02 lasso 3 0.04 2.4e-05 -4.3 -5.4 8.6e-08 -0.04 0.15 0.33 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC147727 0.13 0.02 blup 28 0.04 7.2e-05 7.9 -5.8 7.7e-09 -0.76 0.01 0.88 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma FDX1L 0.06 0.00 blup 53 0.02 5.1e-03 -4.3 -5.9 4.4e-09 0.05 0.01 0.31 TRUE
15 The Cancer Genome Atlas Brain Lower Grade Glioma LOC147727 0.07 0.02 lasso 2 0.02 5.4e-03 7.9 -8.1 4.5e-16 -0.99 0.01 0.85 TRUE
16 The Cancer Genome Atlas Thyroid Carcinoma SLC44A2 0.32 0.22 enet 14 0.25 3.8e-24 7.8 6.2 5.8e-10 0.85 0.05 0.95 FALSE