Best TWAS P=4.86e-14 · Best GWAS P=6.83e-10 conditioned to 0.000142
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | EVI5L | 0.17 | 0.10 | lasso | 7 | 0.12 | 7.9e-10 | 4.3 | 5.4 | 8.3e-08 | -0.03 | 0.02 | 0.92 | TRUE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | MARCH2 | 0.42 | 0.33 | enet | 27 | 0.35 | 5.6e-20 | 4.6 | 5.3 | 1.0e-07 | -0.17 | 0.82 | 0.18 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MYO1F | 0.05 | 0.01 | blup | 42 | 0.03 | 2.2e-04 | -4.9 | -7.5 | 4.9e-14 | 0.32 | 0.03 | 0.37 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | PRAM1 | 0.05 | 0.02 | blup | 44 | 0.01 | 3.4e-02 | -4.4 | -5.3 | 1.1e-07 | 0.01 | 0.01 | 0.49 | FALSE |