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chr22:38,447,444-41,004,384

Best TWAS P=1.04e-09 · Best GWAS P=2.42e-10 conditioned to 0.00585

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADSL	0.09	0.03	lasso	3	0.01	7.7e-02	-6.3	-6.1	1.0e-09	0.91	0.00	0.76	TRUE
6	GTEx	Skin Sun Exposed Lower leg	MGAT3	0.13	0.05	lasso	3	0.02	4.7e-03	-5.7	5.8	7.4e-09	0.01	0.01	0.98	TRUE
4	GTEx	Pituitary	APOBEC3G	0.34	0.04	enet	11	0.11	1.2e-03	4.9	5.7	1.5e-08	0.04	0.14	0.15	TRUE
5	GTEx	Skin Not Sun Exposed Suprapubic	SUN2	0.13	0.00	enet	36	0.02	2.9e-02	3.1	-5.1	2.8e-07	-0.01	0.27	0.04	TRUE
13	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ADSL	0.06	0.02	lasso	2	0.03	6.6e-03	-6.1	-6.1	1.4e-09	0.97	0.00	0.81	FALSE
2	GTEx	Heart Atrial Appendage	MGAT3	0.14	0.14	lasso	2	0.12	3.5e-06	-5.7	5.8	9.0e-09	0.02	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	ADSL	0.03	0.00	blup	33	0.01	8.9e-03	-6.0	-5.7	1.3e-08	0.82	0.01	0.61	FALSE
3	GTEx	Nerve Tibial	SYNGR1	0.26	0.18	enet	27	0.21	3.6e-15	-4.5	-5.5	3.0e-08	-0.04	0.07	0.93	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADSL	0.04	0.03	enet	6	0.03	1.6e-04	-6.2	-5.5	3.1e-08	0.86	0.00	0.94	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	TNRC6B	0.02	0.01	blup	92	0.01	2.7e-03	-4.7	-5.5	4.8e-08	0.82	0.02	0.78	FALSE
1	GTEx	Adipose Subcutaneous	MGAT3	0.08	0.04	lasso	4	0.04	4.3e-04	-5.7	5.4	7.6e-08	0.04	0.02	0.98	FALSE
9	NTR	Blood	SYNGR1	0.03	0.03	enet	6	0.03	1.0e-10	5.2	5.2	1.6e-07	0.01	0.15	0.84	FALSE
8	GTEx	Vagina	APOBEC3G	0.23	0.07	lasso	5	0.06	1.8e-02	4.6	5.2	1.7e-07	0.05	0.11	0.08	FALSE
7	GTEx	Spleen	SYNGR1	0.36	0.41	lasso	2	0.36	3.4e-10	5.2	5.2	2.5e-07	0.01	0.13	0.86	FALSE