[Hub]/) : Traits : Basal metabolic rate :

chr22:38,447,444-41,004,384

Best TWAS P=1.04e-09 · Best GWAS P=2.42e-10 conditioned to 0.00585

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MGAT3 0.08 0.04 lasso 4 0.04 4.3e-04 -5.7 5.4 7.6e-08 0.04 0.02 0.98 FALSE
2 GTEx Heart Atrial Appendage MGAT3 0.14 0.14 lasso 2 0.12 3.5e-06 -5.7 5.8 9.0e-09 0.02 0.01 0.99 FALSE
3 GTEx Nerve Tibial SYNGR1 0.26 0.18 enet 27 0.21 3.6e-15 -4.5 -5.5 3.0e-08 -0.04 0.07 0.93 FALSE
4 GTEx Pituitary APOBEC3G 0.34 0.04 enet 11 0.11 1.2e-03 4.9 5.7 1.5e-08 0.04 0.14 0.15 TRUE
5 GTEx Skin Not Sun Exposed Suprapubic SUN2 0.13 0.00 enet 36 0.02 2.9e-02 3.1 -5.1 2.8e-07 -0.01 0.27 0.04 TRUE
6 GTEx Skin Sun Exposed Lower leg MGAT3 0.13 0.05 lasso 3 0.02 4.7e-03 -5.7 5.8 7.4e-09 0.01 0.01 0.98 TRUE
7 GTEx Spleen SYNGR1 0.36 0.41 lasso 2 0.36 3.4e-10 5.2 5.2 2.5e-07 0.01 0.13 0.86 FALSE
8 GTEx Vagina APOBEC3G 0.23 0.07 lasso 5 0.06 1.8e-02 4.6 5.2 1.7e-07 0.05 0.11 0.08 FALSE
9 NTR Blood SYNGR1 0.03 0.03 enet 6 0.03 1.0e-10 5.2 5.2 1.6e-07 0.01 0.15 0.84 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma TNRC6B 0.02 0.01 blup 92 0.01 2.7e-03 -4.7 -5.5 4.8e-08 0.82 0.02 0.78 FALSE
11 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 1.6e-04 -6.2 -5.5 3.1e-08 0.86 0.00 0.94 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 8.9e-03 -6.0 -5.7 1.3e-08 0.82 0.01 0.61 FALSE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 6.6e-03 -6.1 -6.1 1.4e-09 0.97 0.00 0.81 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 7.7e-02 -6.3 -6.1 1.0e-09 0.91 0.00 0.76 TRUE