[Hub]/) : Traits : Impedance of whole body : ← →

chr9:126,321,003-129,961,152

Best TWAS P=3.28e-11 · Best GWAS P=2.51e-11 conditioned to 0.00276

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	6.1	6.6	3.3e-11	0.04	0.03	0.97	TRUE
7	GTEx	Breast Mammary Tissue	PSMB7	0.11	0.03	lasso	7	0.04	4.7e-03	-6.6	6.3	2.8e-10	0.69	0.03	0.90	TRUE
28	GTEx	Whole Blood	MVB12B	0.09	0.04	lasso	4	0.03	7.2e-04	4.7	-5.3	9.0e-08	0.02	0.10	0.55	TRUE
26	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	6.2	6.5	8.1e-11	0.04	0.02	0.97	FALSE
22	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	-5.3	6.5	9.7e-11	0.05	0.10	0.90	FALSE
20	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	6.3	-6.4	2.1e-10	-0.05	0.02	0.98	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	6.0	-6.1	1.0e-09	-0.02	0.03	0.87	FALSE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	NEK6	0.06	0.01	blup	87	0.04	1.0e-04	6.0	5.9	3.0e-09	0.71	0.04	0.89	FALSE
9	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	-5.5	5.8	5.8e-09	0.04	0.08	0.78	FALSE
2	GTEx	Adipose Subcutaneous	PSMB7	0.08	0.04	lasso	6	0.04	3.4e-04	-4.3	5.8	8.1e-09	0.57	0.10	0.88	FALSE
15	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	-5.7	-5.7	1.1e-08	-0.01	0.47	0.30	FALSE
17	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	-5.5	-5.7	1.4e-08	-0.02	0.42	0.51	FALSE
25	GTEx	Thyroid	NEK6	0.20	0.21	lasso	4	0.20	1.3e-15	-4.9	5.6	1.8e-08	0.64	0.90	0.10	FALSE
12	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	-5.6	-5.6	1.9e-08	-0.01	0.65	0.35	FALSE
23	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	-5.5	-5.6	2.0e-08	-0.02	0.60	0.37	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	-5.6	5.6	2.4e-08	0.01	0.02	0.72	FALSE
11	GTEx	Cells Transformed fibroblasts	PSMB7	0.09	0.07	enet	11	0.06	2.1e-05	5.6	5.6	2.8e-08	0.75	0.34	0.64	FALSE
32	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	-5.5	5.5	3.0e-08	0.02	0.02	0.96	FALSE
14	GTEx	Colon Transverse	PSMB7	0.13	0.02	lasso	3	0.03	1.8e-02	-6.6	5.5	3.2e-08	0.61	0.02	0.82	FALSE
29	The Cancer Genome Atlas	Breast Invasive Carcinoma	NEK6	0.04	0.02	blup	87	0.02	2.5e-05	6.0	5.5	3.2e-08	0.78	0.01	0.98	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB7	0.03	0.04	lasso	4	0.04	1.2e-04	-5.4	5.5	3.7e-08	0.50	0.09	0.83	FALSE
5	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	-5.5	-5.5	4.1e-08	-0.02	0.64	0.33	FALSE
6	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	6.3	-5.5	4.3e-08	-0.05	0.06	0.76	FALSE
18	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	-5.3	-5.5	4.8e-08	-0.13	0.08	0.23	FALSE
27	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	-5.5	-5.4	5.9e-08	-0.03	0.68	0.32	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	-5.5	5.4	6.9e-08	0.01	0.02	0.98	FALSE
16	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	-5.3	5.4	8.2e-08	0.04	0.68	0.31	FALSE
30	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	-5.4	5.4	8.3e-08	0.03	0.03	0.97	FALSE
37	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	-5.5	5.4	8.7e-08	0.01	0.03	0.95	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB7	0.06	0.06	lasso	4	0.04	3.7e-05	-5.3	5.3	9.3e-08	0.56	0.17	0.82	FALSE
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	-5.4	5.3	9.9e-08	0.04	0.69	0.30	FALSE
13	GTEx	Colon Sigmoid	PSMB7	0.15	0.10	lasso	3	0.09	3.3e-04	-5.1	5.3	1.2e-07	0.49	0.30	0.40	FALSE
8	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	-5.4	5.3	1.3e-07	0.02	0.07	0.11	FALSE
19	GTEx	Muscle Skeletal	PPP6C	0.03	0.03	enet	6	0.01	3.0e-02	-5.5	5.3	1.3e-07	0.02	0.40	0.28	FALSE
3	GTEx	Artery Aorta	PSMB7	0.15	0.03	enet	16	0.05	1.4e-03	5.6	5.3	1.5e-07	0.51	0.15	0.31	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	-5.5	5.2	1.6e-07	0.01	0.02	0.98	FALSE
24	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	-5.4	5.2	1.9e-07	0.04	0.21	0.69	FALSE
10	GTEx	Cells Transformed fibroblasts	PPP6C	0.07	0.05	enet	20	0.06	5.2e-05	-5.6	5.2	2.0e-07	0.01	0.51	0.47	FALSE
21	GTEx	Nerve Tibial	NEK6	0.11	0.02	enet	40	0.03	3.9e-03	-6.1	5.1	2.7e-07	0.52	0.03	0.80	FALSE