[Hub]/) : Traits : Impedance of whole body :

chr9:126,321,003-129,961,152

Best TWAS P=3.28e-11 · Best GWAS P=2.51e-11 conditioned to 0.00276

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP6C 0.06 0.10 lasso 3 0.07 3.2e-06 -5.4 5.3 9.9e-08 0.04 0.69 0.30 FALSE
2 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 -4.3 5.8 8.1e-09 0.57 0.10 0.88 FALSE
3 GTEx Artery Aorta PSMB7 0.15 0.03 enet 16 0.05 1.4e-03 5.6 5.3 1.5e-07 0.51 0.15 0.31 FALSE
4 GTEx Artery Tibial GAPVD1 0.11 0.16 enet 19 0.16 6.4e-13 6.1 6.6 3.3e-11 0.04 0.03 0.97 TRUE
5 GTEx Artery Tibial PRPS1P2 0.06 0.06 enet 6 0.05 9.2e-05 -5.5 -5.5 4.1e-08 -0.02 0.64 0.33 FALSE
6 GTEx Brain Cerebellum PRPS1P2 0.09 0.08 enet 16 0.04 2.8e-02 6.3 -5.5 4.3e-08 -0.05 0.06 0.76 FALSE
7 GTEx Breast Mammary Tissue PSMB7 0.11 0.03 lasso 7 0.04 4.7e-03 -6.6 6.3 2.8e-10 0.69 0.03 0.90 TRUE
8 GTEx Breast Mammary Tissue (Male) PPP6C 0.12 0.03 enet 12 0.03 6.5e-02 -5.4 5.3 1.3e-07 0.02 0.07 0.11 FALSE
9 GTEx Breast Mammary Tissue (Female) PPP6C 0.14 0.04 lasso 4 0.04 3.1e-02 -5.5 5.8 5.8e-09 0.04 0.08 0.78 FALSE
10 GTEx Cells Transformed fibroblasts PPP6C 0.07 0.05 enet 20 0.06 5.2e-05 -5.6 5.2 2.0e-07 0.01 0.51 0.47 FALSE
11 GTEx Cells Transformed fibroblasts PSMB7 0.09 0.07 enet 11 0.06 2.1e-05 5.6 5.6 2.8e-08 0.75 0.34 0.64 FALSE
12 GTEx Cells Transformed fibroblasts PRPS1P2 0.09 0.11 enet 8 0.13 9.6e-10 -5.6 -5.6 1.9e-08 -0.01 0.65 0.35 FALSE
13 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 -5.1 5.3 1.2e-07 0.49 0.30 0.40 FALSE
14 GTEx Colon Transverse PSMB7 0.13 0.02 lasso 3 0.03 1.8e-02 -6.6 5.5 3.2e-08 0.61 0.02 0.82 FALSE
15 GTEx Colon Transverse PRPS1P2 0.11 0.10 lasso 1 0.08 1.8e-04 -5.7 -5.7 1.1e-08 -0.01 0.47 0.30 FALSE
16 GTEx Esophagus Mucosa PPP6C 0.07 0.07 enet 21 0.08 7.1e-06 -5.3 5.4 8.2e-08 0.04 0.68 0.31 FALSE
17 GTEx Esophagus Mucosa PRPS1P2 0.07 0.08 lasso 3 0.07 1.5e-05 -5.5 -5.7 1.4e-08 -0.02 0.42 0.51 FALSE
18 GTEx Esophagus Muscularis OLFML2A 0.08 0.00 enet 27 0.00 4.9e-01 -5.3 -5.5 4.8e-08 -0.13 0.08 0.23 FALSE
19 GTEx Muscle Skeletal PPP6C 0.03 0.03 enet 6 0.01 3.0e-02 -5.5 5.3 1.3e-07 0.02 0.40 0.28 FALSE
20 GTEx Muscle Skeletal GAPVD1 0.13 0.10 lasso 3 0.09 4.7e-09 6.3 -6.4 2.1e-10 -0.05 0.02 0.98 FALSE
21 GTEx Nerve Tibial NEK6 0.11 0.02 enet 40 0.03 3.9e-03 -6.1 5.1 2.7e-07 0.52 0.03 0.80 FALSE
22 GTEx Nerve Tibial GAPVD1 0.17 0.08 lasso 10 0.10 9.3e-08 -5.3 6.5 9.7e-11 0.05 0.10 0.90 FALSE
23 GTEx Pancreas PRPS1P2 0.16 0.13 lasso 6 0.12 8.7e-06 -5.5 -5.6 2.0e-08 -0.02 0.60 0.37 FALSE
24 GTEx Skin Sun Exposed Lower leg GAPVD1 0.04 0.01 lasso 4 0.01 3.8e-02 -5.4 5.2 1.9e-07 0.04 0.21 0.69 FALSE
25 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 -4.9 5.6 1.8e-08 0.64 0.90 0.10 FALSE
26 GTEx Thyroid GAPVD1 0.05 0.05 enet 13 0.01 6.6e-02 6.2 6.5 8.1e-11 0.04 0.02 0.97 FALSE
27 GTEx Thyroid PRPS1P2 0.08 0.09 enet 18 0.07 4.0e-06 -5.5 -5.4 5.9e-08 -0.03 0.68 0.32 FALSE
28 GTEx Whole Blood MVB12B 0.09 0.04 lasso 4 0.03 7.2e-04 4.7 -5.3 9.0e-08 0.02 0.10 0.55 TRUE
29 The Cancer Genome Atlas Breast Invasive Carcinoma NEK6 0.04 0.02 blup 87 0.02 2.5e-05 6.0 5.5 3.2e-08 0.78 0.01 0.98 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPP6C 0.07 0.08 lasso 3 0.09 5.4e-10 -5.4 5.4 8.3e-08 0.03 0.03 0.97 FALSE
31 The Cancer Genome Atlas Brain Lower Grade Glioma PPP6C 0.02 0.02 lasso 2 0.01 1.5e-02 -5.6 5.6 2.4e-08 0.01 0.02 0.72 FALSE
32 The Cancer Genome Atlas Lung Adenocarcinoma PPP6C 0.02 0.02 lasso 4 0.02 7.6e-04 -5.5 5.5 3.0e-08 0.02 0.02 0.96 FALSE
33 The Cancer Genome Atlas Prostate Adenocarcinoma GAPVD1 0.02 0.04 enet 4 0.01 9.8e-03 6.0 -6.1 1.0e-09 -0.02 0.03 0.87 FALSE
34 The Cancer Genome Atlas Prostate Adenocarcinoma NEK6 0.06 0.01 blup 87 0.04 1.0e-04 6.0 5.9 3.0e-09 0.71 0.04 0.89 FALSE
35 The Cancer Genome Atlas Prostate Adenocarcinoma PPP6C 0.06 0.08 lasso 7 0.07 1.8e-07 -5.5 5.2 1.6e-07 0.01 0.02 0.98 FALSE
36 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB7 0.03 0.04 lasso 4 0.04 1.2e-04 -5.4 5.5 3.7e-08 0.50 0.09 0.83 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma PPP6C 0.05 0.04 blup 46 0.03 3.8e-03 -5.5 5.4 8.7e-08 0.01 0.03 0.95 FALSE
38 The Cancer Genome Atlas Thyroid Carcinoma PPP6C 0.08 0.13 enet 9 0.13 5.5e-13 -5.5 5.4 6.9e-08 0.01 0.02 0.98 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma PSMB7 0.06 0.06 lasso 4 0.04 3.7e-05 -5.3 5.3 9.3e-08 0.56 0.17 0.82 FALSE