Best TWAS P=1.46e-09 · Best GWAS P=3.72e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PPP2R3C | 0.21 | 0.12 | lasso | 10 | 0.14 | 2.6e-11 | 5.8 | -5.5 | 2.9e-08 | -0.57 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-85K15.2 | 0.06 | 0.01 | lasso | 6 | 0.02 | 2.1e-02 | 5.3 | 5.4 | 7.6e-08 | 0.59 | 0.07 | 0.61 | FALSE |
| 3 | GTEx | Brain Cerebellum | FAM177A1 | 0.13 | 0.04 | lasso | 3 | 0.04 | 1.9e-02 | 5.9 | -6.0 | 1.5e-09 | -0.99 | 0.01 | 0.92 | TRUE |
| 4 | GTEx | Esophagus Mucosa | SRP54 | 0.13 | 0.05 | lasso | 5 | 0.05 | 1.6e-04 | 5.8 | -6.0 | 2.2e-09 | -0.83 | 0.00 | 0.99 | FALSE |
| 5 | GTEx | Nerve Tibial | FAM177A1 | 0.23 | 0.07 | enet | 37 | 0.10 | 1.1e-07 | 5.9 | -5.2 | 2.2e-07 | -0.77 | 0.01 | 0.99 | FALSE |
| 6 | GTEx | Testis | FAM177A1 | 0.30 | 0.16 | lasso | 5 | 0.23 | 1.2e-10 | 2.7 | 5.3 | 1.4e-07 | 0.83 | 0.02 | 0.98 | FALSE |
| 7 | NTR | Blood | KIAA0391 | 0.05 | 0.05 | lasso | 10 | 0.05 | 2.4e-15 | 5.8 | 5.6 | 1.9e-08 | 0.63 | 0.00 | 1.00 | FALSE |
| 8 | YFS | Blood | KIAA0391 | 0.29 | 0.36 | lasso | 7 | 0.38 | 5.8e-132 | 5.8 | 5.8 | 7.7e-09 | 0.62 | 0.00 | 1.00 | FALSE |