[Hub]/) : Traits : Impedance of whole body :

chr2:240,826,197-242,812,080

Best TWAS P=1.92e-14 · Best GWAS P=1.99e-14 conditioned to 2.2e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PASK 0.17 0.09 enet 13 0.09 8.3e-08 5.6 -6.0 2.3e-09 -0.66 0.92 0.08 FALSE
2 GTEx Artery Aorta CAPN10-AS1 0.14 0.00 lasso 5 0.00 2.6e-01 5.6 5.6 2.3e-08 -0.04 0.06 0.05 TRUE
3 GTEx Esophagus Mucosa PASK 0.19 0.13 lasso 6 0.14 1.1e-09 5.7 -6.0 1.6e-09 -0.59 1.00 0.00 FALSE
4 GTEx Heart Left Ventricle PASK 0.10 0.03 lasso 6 0.03 9.4e-03 -5.0 -7.0 3.3e-12 -0.62 0.03 0.81 FALSE
5 GTEx Lung PASK 0.09 0.02 lasso 2 0.03 3.7e-03 -3.5 -5.7 1.1e-08 -0.47 0.44 0.05 FALSE
6 GTEx Muscle Skeletal PASK 0.06 0.00 enet 13 0.01 8.6e-02 5.6 -6.2 7.2e-10 -0.58 0.02 0.70 FALSE
7 GTEx Nerve Tibial PASK 0.26 0.18 enet 12 0.22 1.0e-15 5.6 -6.8 8.5e-12 -0.59 1.00 0.00 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic PASK 0.28 0.16 enet 17 0.19 1.9e-10 5.0 -6.3 3.3e-10 -0.69 0.96 0.03 FALSE
9 GTEx Skin Sun Exposed Lower leg PASK 0.27 0.18 enet 10 0.18 4.5e-15 5.0 -5.5 3.2e-08 -0.58 1.00 0.00 FALSE
10 GTEx Small Intestine Terminal Ileum MTERFD2 0.37 0.24 lasso 3 0.18 7.3e-05 6.9 -7.1 1.5e-12 -0.57 0.08 0.57 FALSE
11 GTEx Testis MTERFD2 0.43 0.17 enet 32 0.25 1.4e-11 6.9 6.5 6.6e-11 0.58 0.10 0.90 FALSE
12 GTEx Thyroid PASK 0.22 0.04 enet 41 0.09 1.2e-07 5.9 -5.5 5.1e-08 -0.49 0.44 0.51 FALSE
13 GTEx Thyroid MTERFD2 0.12 0.09 lasso 2 0.08 1.8e-06 7.1 -6.1 9.3e-10 -0.47 0.07 0.93 FALSE
14 GTEx Whole Blood PASK 0.25 0.15 enet 10 0.21 4.4e-19 6.8 -7.7 1.9e-14 -0.57 0.16 0.84 TRUE
15 GTEx Whole Blood MTERFD2 0.10 0.06 enet 16 0.06 3.0e-06 7.2 -6.5 8.1e-11 -0.48 0.05 0.94 FALSE
16 METSIM Adipose PASK 0.09 0.03 bslmm 441 0.08 9.4e-12 7.7 -6.0 2.3e-09 -0.71 0.00 1.00 FALSE
17 NTR Blood PASK 0.08 0.09 bslmm 437 0.09 1.0e-26 6.9 -6.9 3.9e-12 -0.60 0.22 0.78 FALSE
18 ROSMAP Brain Pre-frontal Cortex PPP1R7 0.08 0.06 enet 18 0.08 1.6e-10 -3.2 5.2 2.5e-07 0.47 1.00 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex SNED1 0.17 0.12 lasso 4 0.14 5.2e-18 4.4 6.0 2.4e-09 0.54 1.00 0.00 FALSE
20 YFS Blood PASK 0.31 0.46 lasso 11 0.48 1.8e-181 7.1 -7.5 4.4e-14 -0.62 0.10 0.90 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PASK 0.04 0.00 blup 92 0.01 3.2e-02 7.0 -6.6 5.1e-11 -0.50 0.04 0.21 FALSE